DK0841923T3 - 1H-4(5)-substituerede imidazolderivater - Google Patents
1H-4(5)-substituerede imidazolderivaterInfo
- Publication number
- DK0841923T3 DK0841923T3 DK96921378T DK96921378T DK0841923T3 DK 0841923 T3 DK0841923 T3 DK 0841923T3 DK 96921378 T DK96921378 T DK 96921378T DK 96921378 T DK96921378 T DK 96921378T DK 0841923 T3 DK0841923 T3 DK 0841923T3
- Authority
- DK
- Denmark
- Prior art keywords
- formula
- present
- lower alkyl
- disorders
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Luminescent Compositions (AREA)
- Liquid Crystal Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47992595A | 1995-06-07 | 1995-06-07 | |
| PCT/US1996/009498 WO1996040126A1 (en) | 1995-06-07 | 1996-06-06 | 1h-4(5)-substituted imidazole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0841923T3 true DK0841923T3 (da) | 2003-01-27 |
Family
ID=23905996
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96921378T DK0841923T3 (da) | 1995-06-07 | 1996-06-06 | 1H-4(5)-substituerede imidazolderivater |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0841923B1 (pt) |
| JP (1) | JPH11507631A (pt) |
| AT (1) | ATE224193T1 (pt) |
| AU (1) | AU713166B2 (pt) |
| CA (1) | CA2222652A1 (pt) |
| DE (1) | DE69623784T2 (pt) |
| DK (1) | DK0841923T3 (pt) |
| ES (1) | ES2184876T3 (pt) |
| NZ (1) | NZ311318A (pt) |
| PT (1) | PT841923E (pt) |
| WO (1) | WO1996040126A1 (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6133291A (en) * | 1998-10-16 | 2000-10-17 | Schering Corporation | N-(imidazolylalkyl)substituted cyclic amines as histamine-H3 agonists or antagonists |
| EP1147092A1 (en) * | 1999-01-18 | 2001-10-24 | Novo Nordisk A/S | Substituted imidazoles, their preparation and use |
| US6908926B1 (en) | 1999-04-16 | 2005-06-21 | Novo Nordisk A/S | Substituted imidazoles, their preparation and use |
| US6437147B1 (en) | 2000-03-17 | 2002-08-20 | Novo Nordisk | Imidazole compounds |
| US6610721B2 (en) | 2000-03-17 | 2003-08-26 | Novo Nordisk A/S | Imidazo heterocyclic compounds |
| JP2004506012A (ja) | 2000-08-17 | 2004-02-26 | グリアテツク・インコーポレイテツド | Ｈ３剤としての新規脂環式イミダゾール |
| AU2005247808B2 (en) * | 2004-05-31 | 2011-02-10 | Msd K.K. | Quinazoline derivative |
| EP1707203A1 (en) | 2005-04-01 | 2006-10-04 | Bioprojet | Treatment of parkinson's disease obstructive sleep apnea, dementia with lewy bodies, vascular dementia with non-imidazole alkylamines histamine H3- receptor ligands |
| EP1717233A1 (en) | 2005-04-29 | 2006-11-02 | Bioprojet | Histamine H3-receptor ligands and their therapeutic application |
| EP1717235A3 (en) | 2005-04-29 | 2007-02-28 | Bioprojet | Phenoxypropylpiperidines and -pyrrolidines and their use as histamine H3-receptor ligands |
| WO2013151982A1 (en) | 2012-04-03 | 2013-10-10 | Arena Pharmaceuticals, Inc. | Methods and compounds useful in treating pruritus, and methods for identifying such compounds |
| EP2740474A1 (en) | 2012-12-05 | 2014-06-11 | Instituto Europeo di Oncologia S.r.l. | Cyclopropylamine derivatives useful as inhibitors of histone demethylases kdm1a |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2586562B1 (fr) * | 1985-09-02 | 1989-03-10 | Inst Nat Sante Rech Med | Composition pharmaceutique contenant de l'a-methylhistamine |
| DK0618905T3 (da) * | 1991-12-18 | 1995-12-04 | Schering Corp | Imidazolyl-alkyl-piperazin- og -diazepinderivater som histamin H3-agonister/antagonister |
-
1996
- 1996-06-06 JP JP9501805A patent/JPH11507631A/ja not_active Ceased
- 1996-06-06 DK DK96921378T patent/DK0841923T3/da active
- 1996-06-06 PT PT96921378T patent/PT841923E/pt unknown
- 1996-06-06 CA CA002222652A patent/CA2222652A1/en not_active Abandoned
- 1996-06-06 EP EP96921378A patent/EP0841923B1/en not_active Expired - Lifetime
- 1996-06-06 ES ES96921378T patent/ES2184876T3/es not_active Expired - Lifetime
- 1996-06-06 DE DE69623784T patent/DE69623784T2/de not_active Expired - Fee Related
- 1996-06-06 AT AT96921378T patent/ATE224193T1/de not_active IP Right Cessation
- 1996-06-06 AU AU62482/96A patent/AU713166B2/en not_active Ceased
- 1996-06-06 NZ NZ311318A patent/NZ311318A/xx unknown
- 1996-06-06 WO PCT/US1996/009498 patent/WO1996040126A1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| DE69623784T2 (de) | 2003-05-15 |
| DE69623784D1 (de) | 2002-10-24 |
| EP0841923A4 (en) | 1999-04-28 |
| NZ311318A (en) | 2000-08-25 |
| ES2184876T3 (es) | 2003-04-16 |
| WO1996040126A1 (en) | 1996-12-19 |
| CA2222652A1 (en) | 1996-12-19 |
| JPH11507631A (ja) | 1999-07-06 |
| ATE224193T1 (de) | 2002-10-15 |
| EP0841923B1 (en) | 2002-09-18 |
| AU713166B2 (en) | 1999-11-25 |
| EP0841923A1 (en) | 1998-05-20 |
| AU6248296A (en) | 1996-12-30 |
| PT841923E (pt) | 2003-01-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE224193T1 (de) | 1h-4(5)-substituierte imidazolderivate. | |
| PE20021005A1 (es) | Quinazolinas como inhibidores de mmp-13 | |
| RU2004109812A (ru) | Ингибиторы цистеинпротеазы 2-циано-4-аминопиримидинового строения с ингибирующим действием на катепсин к для лечения воспалительных и других заболеваний | |
| ATE135701T1 (de) | Imidazolderivate, starke und selektive angiotensin-ii-rezeptor-antagonisten | |
| ATE466860T1 (de) | Cgrp-rezeptorantagonisten | |
| MX9709211A (es) | Derivados de 2-(1h-4(5)-imidazoil) ciclopropilo. | |
| PE20040583A1 (es) | Nuevos derivados de benzimidazol | |
| PE20030226A1 (es) | Compuestos arilicos sustituidos con quinuclidinas para el tratamiento de enfermedades | |
| PE20020917A1 (es) | Derivados de imidazol como bloqueadores del receptor n-metil-d-aspartato | |
| PE20011035A1 (es) | Ureas ciclicas sustituidas como antagonistas de los receptores de neuroquinina | |
| PE20060770A1 (es) | Derivados de n-[(4,5-difenil-3-alquil-2-tienil)metil]amina como antagonistas de los receptores cannabinoides cb1 | |
| MXPA02011418A (es) | 1-aminoalquil-lactamas sustituidas y su uso como antagonistas del receptor muscarinico. | |
| EA200200731A1 (ru) | Производные фенилпиперазинила | |
| ATE316078T1 (de) | 1,3,5-triazine-2,4,6-trione, herstellung und anwendungen als antagonisten der gonadotropin- freisetzenden hormonrezeptoren | |
| UY25864A1 (es) | Derivados de acetamida antagonistas de receptor de nk1 | |
| NZ504316A (en) | Pyrimidine substituted carboxylic acid derivatives which have amido side-chains useful as endothelin receptor antagonists | |
| PE20090967A1 (es) | Derivados de imidazolidina 2,4-diona como moduladores del receptor npy y2 | |
| PE20050475A1 (es) | Antagonistas de la hormona concentradora de melanina | |
| BRPI0510564A (pt) | compostos e tautÈmeros, estereoisÈmeros, e sais farmacologicamente aceitáveis dos mesmos, composições farmacêuticas, método para preparar composições farmacêuticas, e, uso de um composto | |
| RU2002121777A (ru) | Новые производные имидазола | |
| RU2005102586A (ru) | 2,5-замещенные производные пиримидина в качестве антагонистов ix рецептора ccr-3 | |
| DE60224509D1 (de) | Imidazolderivate verwendbar als histamin h3 rezeptorliganden | |
| PT1335928E (pt) | Agonistas selectivos do receptor de glucocorticoides | |
| EA199800062A1 (ru) | Новые гетероциклические соединения для лечения боли и их применение | |
| MX9709210A (es) | Derivados de imidazol ih-4(5)-substituidos. |