DK0833938T3 - Reduktion af ketongrupper - Google Patents

Reduktion af ketongrupper

Info

Publication number
DK0833938T3
DK0833938T3 DK96920921T DK96920921T DK0833938T3 DK 0833938 T3 DK0833938 T3 DK 0833938T3 DK 96920921 T DK96920921 T DK 96920921T DK 96920921 T DK96920921 T DK 96920921T DK 0833938 T3 DK0833938 T3 DK 0833938T3
Authority
DK
Denmark
Prior art keywords
pct
compound
formula
produced
reduction
Prior art date
Application number
DK96920921T
Other languages
Danish (da)
English (en)
Inventor
Christopher David Reeve
Original Assignee
Avecia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avecia Ltd filed Critical Avecia Ltd
Application granted granted Critical
Publication of DK0833938T3 publication Critical patent/DK0833938T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/002—Nitriles (-CN)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/002—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
DK96920921T 1995-06-23 1996-06-17 Reduktion af ketongrupper DK0833938T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9512837.7A GB9512837D0 (en) 1995-06-23 1995-06-23 reduction of ketone groups
PCT/GB1996/001422 WO1997000968A1 (en) 1995-06-23 1996-06-17 Reduction of ketone groups

Publications (1)

Publication Number Publication Date
DK0833938T3 true DK0833938T3 (da) 2003-07-14

Family

ID=10776577

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96920921T DK0833938T3 (da) 1995-06-23 1996-06-17 Reduktion af ketongrupper

Country Status (12)

Country Link
US (1) US6001615A (ja)
EP (1) EP0833938B1 (ja)
JP (1) JP3580825B2 (ja)
AT (1) ATE234935T1 (ja)
AU (1) AU6230696A (ja)
CA (1) CA2221800C (ja)
CZ (1) CZ291886B6 (ja)
DE (1) DE69626820T2 (ja)
DK (1) DK0833938T3 (ja)
ES (1) ES2194995T3 (ja)
GB (1) GB9512837D0 (ja)
WO (1) WO1997000968A1 (ja)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1077212B1 (en) * 1998-04-30 2003-08-20 Kaneka Corporation Process for producing 6-cyanomethyl-1,3-dioxane-4-acetic acid derivatives
DK1619191T3 (da) 1998-08-05 2011-01-31 Kaneka Corp Fremgangsmåde til fremstilling af optisk aktive 2-[6-hydroxymethyl)-1,3-dioxan-4-yl]-eddikesyre-derivater
DE19857302C2 (de) * 1998-12-14 2000-10-26 Forschungszentrum Juelich Gmbh Verfahren zur enantioselektiven Reduktion von 3,5-Dioxocarbonsäuren, deren Salze und Ester
EP1194582A1 (de) * 1999-07-09 2002-04-10 Forschungszentrum Jülich Gmbh Verfahren zur reduktion von keto-carbonsäuren und deren estern
DE19937825B4 (de) * 1999-07-09 2005-08-11 Forschungszentrum Jülich GmbH Verfahren zur Reduktion von Hydroxyketo-Carbonsäuren und deren Estern
AU1551701A (en) * 1999-12-03 2001-06-12 Kaneka Corporation Novel carbonyl reductase, gene thereof and method of using the same
GB0011120D0 (en) 2000-05-09 2000-06-28 Avecia Ltd Process
WO2002063028A1 (fr) 2001-02-02 2002-08-15 Mitsubishi Chemical Corporation Procede de production d'esters d'acide (3r,5s)-(e)-7-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl]-3,5-dihydroxyhept-6-enique
KR100451413B1 (ko) * 2001-12-28 2004-10-06 한국과학기술연구원 클루이베로마이시스 마르시아누스의 카르보닐 환원효소를이용한 카르보닐 화합물의 환원반응
BR0305767A (pt) * 2002-08-09 2005-05-24 Codexis Inc Métodos e composições para a preparação de derivados de ácido 4-substituìdo 3-hidroxibutìrico
EP1654356A1 (en) * 2003-08-11 2006-05-10 Codexis, Inc. Improved halohydrin dehalogenases and related polynucleotides
BRPI0413492A (pt) * 2003-08-11 2006-10-17 Codexis Inc polipeptìdeo, polinucleotìdeo, sequência de ácido nucleico isolado, vetor de expressão, célula hospedeira, método de preparar um polipeptìdeo de gdh, e, composição
US7588928B2 (en) * 2003-08-11 2009-09-15 Codexis, Inc. Halohydrin dehalogenases and related polynucleotides
AU2004266100A1 (en) 2003-08-11 2005-03-03 Codexis, Inc. Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives and vicinal cyano, hydroxy substituted carboxylic acid esters
US7541171B2 (en) * 2003-08-11 2009-06-02 Codexis, Inc. Halohydrin dehalogenases and related polynucleotides
US7629157B2 (en) * 2003-08-11 2009-12-08 Codexis, Inc. Ketoreductase polypeptides and related polynucleotides
AT503017B1 (de) * 2005-12-19 2007-07-15 Iep Gmbh Verfahren zur enantioselektiven enzymatischen reduktion von hydroxyketoverbindungen
DE102006010994A1 (de) * 2006-03-09 2007-09-13 Wacker Chemie Ag Verfahren zur enzymatischen Herstellung von chiralen Alkoholen
CN101528917B (zh) 2006-10-02 2015-07-29 科德克希思公司 用于制备立体异构纯的他汀类及其合成中间体的组合物和方法
WO2008059366A2 (en) * 2006-11-17 2008-05-22 Pfizer Products Inc. Process for the preparation of cis-1, 3-diols from the corresponding beta-hydroxy ketones employing microbial ketone reductases
US8748143B2 (en) 2007-09-13 2014-06-10 Codexis, Inc. Ketoreductase polypeptides for the reduction of acetophenones
EP2379713A4 (en) * 2008-12-18 2013-07-10 Codexis Inc RECOMBINANT HALOHYDRIN DEHALOGENASE POLYPEPTIDES
MY159487A (en) 2010-02-12 2017-01-13 Gevo Inc Reduced by-product accumulation for improved production of isobutanol
CN102676596A (zh) * 2011-03-16 2012-09-19 苏州国镝医药科技有限公司 生物酶手性合成立普妥中间体ats-7

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3724197A1 (de) * 1987-07-22 1989-02-02 Merck Patent Gmbh Verfahren zur reduktion von ketonen
US5003080A (en) * 1988-02-22 1991-03-26 Warner-Lambert Company Process for trans-6-(2-(substituted-pyrrol-1-yl)alkyl)pryan-2-one inhibitors of cholesterol synthesis
US5155251A (en) * 1991-10-11 1992-10-13 Warner-Lambert Company Process for the synthesis of (5R)-1,1-dimethylethyl-6-cyano-5-hydroxy-3-oxo-hexanoate
US5324662A (en) * 1992-05-15 1994-06-28 E. R. Squibb & Sons, Inc. Stereoselective microbial or enzymatic reduction of 3,5-dioxo esters to 3-hydroxy-5-oxo, 3-oxo-5-hydroxy, and 3,5-dihydroxy esters

Also Published As

Publication number Publication date
AU6230696A (en) 1997-01-22
GB9512837D0 (en) 1995-08-23
DE69626820T2 (de) 2004-02-12
JP3580825B2 (ja) 2004-10-27
CZ291886B6 (cs) 2003-06-18
ATE234935T1 (de) 2003-04-15
CA2221800C (en) 2008-10-28
CA2221800A1 (en) 1997-01-09
CZ412997A3 (cs) 1998-03-18
EP0833938A1 (en) 1998-04-08
DE69626820D1 (de) 2003-04-24
US6001615A (en) 1999-12-14
ES2194995T3 (es) 2003-12-01
WO1997000968A1 (en) 1997-01-09
JPH11507204A (ja) 1999-06-29
EP0833938B1 (en) 2003-03-19

Similar Documents

Publication Publication Date Title
DK0833938T3 (da) Reduktion af ketongrupper
DE69719201D1 (de) Verfahren zur herstellung von ecteinascidin-verbindungen
NO20003111D0 (no) Ortho-anthranilamidderivater som antikoagulanter
DE59108707D1 (de) Verfahren zur Herstellung von Oxetanonen
DE69737683D1 (de) Antikörper gegen die ed-b domäne von fibronektin, ihre herstellung und verwendungen
DE69434696D1 (de) Verfahren zur Herstellung von Verbindungen geeignet als Zwischenprodukte
DE69132318D1 (de) Verfahren zur herstellung von pyrimidinverbindungen
ATE297928T1 (de) Verbesserte verfahren zur herstellung von vernetzt verbrückten macropolycyclen
DK0923568T5 (da) Hidtil ukendte benzofuran-4-carboxamider
AU8979291A (en) 2-(2,4,5-substituted phenyl)hydantoin compounds
DE60326819D1 (de) Verfahren zur herstellung von inhibitoren der hmg-coa-reduktase
DK0874841T3 (da) 1-Benzensulfonylpyrrolidin-derivater som antagonister af bradykinin-receptoren
DE69706382D1 (de) Verfahren zur herstellung von 2,2'-bipyrrolyl-pyrromethen-derivaten (prodigiosine)
ATE256110T1 (de) Piperindinverbindungen als calcium-kanal-blocker
DK1246813T3 (da) Fremgangsmåde til fremstilling af Citalopram
DE59910677D1 (de) Verfahren sowie neue zwischenprodukte zur herstellung von isoxazolin-3-yl-acylbenzolen
ATE210662T1 (de) Verfahren zur herstellung von epoxiden
DE69604050D1 (de) Verfahren zur herstellung von 2-(substituierten benzoyl)-1,3 cyclohexanedionen
DK0852580T3 (da) Fremgangsmåde til fremstilling af dihydroxypyrimidin-derivater
ATE277898T1 (de) Verfahren zu herstellung von taxol
AR008746A1 (es) Metodo para inhibir la adhesion de bacterias a una superficie sumergible, un metodo para controlar la biosuciedad de un sistema acuoso, y una composicionpara controlar la suciedad en un sistema acuoso.
ATE250042T1 (de) Verfahren zur herstellung von cyclen
CO5011110A1 (es) Nuevos derivados de 2-(3h)-oxazolona
ATE322481T1 (de) Zwischenverbindung zur herstellung von carvedilol
DE69828907D1 (de) Synthese von 11-aryl-5,6-dihydro-11h-dibenz(b,e)azepinen