DK0817858T3 - Vektorer, som indeholder terapeutiske gener for antimikrobielle peptider, til anvendelse ved genterapi - Google Patents

Vektorer, som indeholder terapeutiske gener for antimikrobielle peptider, til anvendelse ved genterapi

Info

Publication number
DK0817858T3
DK0817858T3 DK96907398T DK96907398T DK0817858T3 DK 0817858 T3 DK0817858 T3 DK 0817858T3 DK 96907398 T DK96907398 T DK 96907398T DK 96907398 T DK96907398 T DK 96907398T DK 0817858 T3 DK0817858 T3 DK 0817858T3
Authority
DK
Denmark
Prior art keywords
vectors
relates
present
antimicrobial peptides
gene therapy
Prior art date
Application number
DK96907398T
Other languages
Danish (da)
English (en)
Inventor
Walter H Guenzburg
David Winder
Robert Michael Saller
Original Assignee
Gsf Forschungszentrum Umwelt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gsf Forschungszentrum Umwelt filed Critical Gsf Forschungszentrum Umwelt
Application granted granted Critical
Publication of DK0817858T3 publication Critical patent/DK0817858T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • C07K14/43572—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from bees
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Insects & Arthropods (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK96907398T 1995-03-09 1996-03-08 Vektorer, som indeholder terapeutiske gener for antimikrobielle peptider, til anvendelse ved genterapi DK0817858T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK24395 1995-03-09
PCT/EP1996/001001 WO1996028563A1 (en) 1995-03-09 1996-03-08 Vectors carrying therapeutic genes encoding antimicrobial peptides for gene therapy

Publications (1)

Publication Number Publication Date
DK0817858T3 true DK0817858T3 (da) 2003-08-11

Family

ID=8091353

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96907398T DK0817858T3 (da) 1995-03-09 1996-03-08 Vektorer, som indeholder terapeutiske gener for antimikrobielle peptider, til anvendelse ved genterapi

Country Status (10)

Country Link
US (1) US7022319B1 (ja)
EP (1) EP0817858B1 (ja)
JP (1) JP3908274B2 (ja)
AT (1) ATE238427T1 (ja)
AU (1) AU5103996A (ja)
DE (1) DE69627644T2 (ja)
DK (1) DK0817858T3 (ja)
ES (1) ES2198479T3 (ja)
PT (1) PT817858E (ja)
WO (1) WO1996028563A1 (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2198210C (en) * 1994-09-02 2006-07-11 Walter Henry Gunzburg Non self-inactivating, expression targeted retroviral vectors
GB9621680D0 (en) 1996-10-17 1996-12-11 Oxford Biomedica Ltd Lentiviral vectors
US6924123B2 (en) 1996-10-29 2005-08-02 Oxford Biomedica (Uk) Limited Lentiviral LTR-deleted vector
GB9720465D0 (en) * 1997-09-25 1997-11-26 Oxford Biomedica Ltd Dual-virus vectors
JP2001517433A (ja) 1997-09-24 2001-10-09 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 非霊長類レンチウイルスベクターおよびパッケージングシステム
GB2344592B (en) * 1997-09-25 2002-09-11 Oxford Biomedica Ltd Retroviral vectors comprising a functional splice donor site and a functional splice acceptor site
ES2229674T3 (es) 1998-01-06 2005-04-16 Institut Fur Virologie Teilrechtsfahiges Institut An Der Veterinarmedizinischen Universitat Wien Verctor retroviral reconstituyente (vector re con) para la expresion de genes dirigidos.
GB9817693D0 (en) * 1998-08-14 1998-10-07 Bridgehead Technologies Limite Virally-mediated targeting of drugs and genetic material
DE19910650A1 (de) * 1999-03-10 2000-09-21 Gsf Forschungszentrum Umwelt Auf HERV-LTR-Sequenzen basierende retrovirale Expressionsvektoren
GB9906615D0 (en) * 1999-03-22 1999-05-19 Oxford Biomedica Ltd Vector
WO2008154644A1 (en) * 2007-06-12 2008-12-18 Case Western Reserve University Targeted cell death
JP2012533521A (ja) 2008-07-17 2012-12-27 ニュートリペップ・ピーティーワイ・リミテッド 治療剤

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0383770B1 (en) * 1987-07-06 1995-09-13 Louisiana State University and Agricultural and Mechanical College Inhibition of eucaryotic pathogens and neoplasms with lytic peptides
US4822608A (en) 1987-09-14 1989-04-18 Vespa Laboratories, Inc. Methods and compositions for the treatment of mammalian infections employing medicaments comprising hymenoptera venom or proteinaceous or polypeptide components thereof
EP0371119B1 (en) 1988-05-17 1996-09-04 Sloan-Kettering Institute For Cancer Research Retroviral vector
US5658775A (en) * 1988-05-17 1997-08-19 Sloan-Kettering Institute For Cancer Research Double copy retroviral vector
US5124263A (en) * 1989-01-12 1992-06-23 Wisconsin Alumni Research Foundation Recombination resistant retroviral helper cell and products produced thereby
GB8919607D0 (en) 1989-08-30 1989-10-11 Wellcome Found Novel entities for cancer therapy
DE69011870T2 (de) * 1989-12-07 1994-12-15 Strahlen Umweltforsch Gmbh Verfahren und zubereitung für die behandlung von hiv-infizierten säugetieren.
US6027722A (en) * 1990-10-25 2000-02-22 Nature Technology Corporation Vectors for gene transfer
NZ244306A (en) * 1991-09-30 1995-07-26 Boehringer Ingelheim Int Composition for introducing nucleic acid complexes into eucaryotic cells, complex containing nucleic acid and endosomolytic agent, peptide with endosomolytic domain and nucleic acid binding domain and preparation
JP3524918B2 (ja) * 1991-10-25 2004-05-10 サン ディエゴ リージョナル キャンサー センター 癌のリンホカイン遺伝子療法
WO1995006415A1 (en) 1993-08-30 1995-03-09 Baylor College Of Medicine Senescent cell-derived inhibitors of dna synthesis
US5302706A (en) 1991-12-16 1994-04-12 Baylor College Of Medicine Senescent cell derived inhibitors of DNA synthesis
WO1994029437A1 (en) 1993-06-07 1994-12-22 University Of Medicine & Dentistry Of New Jersey Highly-efficient, self-inactivating, recombination-free, u3-free retroviral vectors
WO1995000178A1 (en) 1993-06-25 1995-01-05 Board Of Regents, The University Of Texas System Pore-forming and superantigen encoding toxin cassettes for gene therapy
AU7321294A (en) * 1993-06-30 1995-01-24 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College, The Transformed eukaryotic cells, and transposon-based transformation vectors
WO1995013375A1 (en) 1993-11-10 1995-05-18 The Johns Hopkins University Tumor suppressor waf1
CA2198210C (en) * 1994-09-02 2006-07-11 Walter Henry Gunzburg Non self-inactivating, expression targeted retroviral vectors
JPH11508441A (ja) 1995-03-09 1999-07-27 ババリアン・ノルディック・リサーチ・インスティテュート・アクティーゼルスカブ 遺伝子治療用の新規組換えｄｎａベクター
GB9510272D0 (en) 1995-05-22 1995-07-19 Isis Innovation Retroviral vectors
PT835137E (pt) 1995-06-27 2004-12-31 Gsf Forschungszentrum Umwelt U Celulas encapsuladas produtoras de particulas virais
AU6987696A (en) 1995-09-06 1997-03-27 Bavarian Nordic Research Institute A/S The use of the wap of mmtv regulatory sequences for targeted expression of linked heterologous genes in human mammary cells, including human mammary carcinoma cells
US5863904A (en) 1995-09-26 1999-01-26 The University Of Michigan Methods for treating cancers and restenosis with P21
AU1334999A (en) 1997-10-20 1999-05-10 Universita Degli Studi Di Padova A packaging cell line producing siv-pseudotyped mlv
ES2229674T3 (es) 1998-01-06 2005-04-16 Institut Fur Virologie Teilrechtsfahiges Institut An Der Veterinarmedizinischen Universitat Wien Verctor retroviral reconstituyente (vector re con) para la expresion de genes dirigidos.

Also Published As

Publication number Publication date
ES2198479T3 (es) 2004-02-01
WO1996028563A1 (en) 1996-09-19
JPH11503305A (ja) 1999-03-26
ATE238427T1 (de) 2003-05-15
US7022319B1 (en) 2006-04-04
PT817858E (pt) 2003-09-30
JP3908274B2 (ja) 2007-04-25
EP0817858B1 (en) 2003-04-23
EP0817858A1 (en) 1998-01-14
DE69627644D1 (de) 2003-05-28
AU5103996A (en) 1996-10-02
DE69627644T2 (de) 2004-02-19

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