DK0804591T3 - Serumparaoxonase - Google Patents
SerumparaoxonaseInfo
- Publication number
- DK0804591T3 DK0804591T3 DK95925340T DK95925340T DK0804591T3 DK 0804591 T3 DK0804591 T3 DK 0804591T3 DK 95925340 T DK95925340 T DK 95925340T DK 95925340 T DK95925340 T DK 95925340T DK 0804591 T3 DK0804591 T3 DK 0804591T3
- Authority
- DK
- Denmark
- Prior art keywords
- serum paraoxonase
- polypeptide
- disclosed
- present
- polypeptides
- Prior art date
Links
- 102000006996 Aryldialkylphosphatase Human genes 0.000 title abstract 3
- 108010008184 Aryldialkylphosphatase Proteins 0.000 title abstract 3
- 210000002966 serum Anatomy 0.000 title abstract 3
- 229920001184 polypeptide Polymers 0.000 abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 4
- 108020004414 DNA Proteins 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 208000007964 Organophosphate Poisoning Diseases 0.000 abstract 1
- 239000000729 antidote Substances 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
- 230000016273 neuron death Effects 0.000 abstract 1
- 150000007523 nucleic acids Chemical group 0.000 abstract 1
- 238000010188 recombinant method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
- Y10S530/809—Fused cells, e.g. hybridoma
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Plant Pathology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/270,583 US5629193A (en) | 1994-07-05 | 1994-07-05 | Paraoxonase |
| PCT/US1995/008111 WO1996001322A1 (en) | 1994-07-05 | 1995-06-28 | Serum paraoxonase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0804591T3 true DK0804591T3 (da) | 2003-01-20 |
Family
ID=23031914
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95925340T DK0804591T3 (da) | 1994-07-05 | 1995-06-28 | Serumparaoxonase |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US5629193A (da) |
| EP (2) | EP0804591B1 (da) |
| JP (2) | JPH10502255A (da) |
| KR (1) | KR970704887A (da) |
| CN (1) | CN1151760A (da) |
| AT (1) | ATE224953T1 (da) |
| CA (1) | CA2194390A1 (da) |
| DE (1) | DE69528379T2 (da) |
| DK (1) | DK0804591T3 (da) |
| ES (1) | ES2180648T3 (da) |
| NZ (1) | NZ289607A (da) |
| PT (1) | PT804591E (da) |
| WO (1) | WO1996001322A1 (da) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5629193A (en) | 1994-07-05 | 1997-05-13 | Human Genome Sciences, Inc. | Paraoxonase |
| GB9511412D0 (en) * | 1995-06-06 | 1995-08-02 | Johnson Matthey Plc | Improvements in emission control |
| US7541519B2 (en) * | 1995-12-14 | 2009-06-02 | Cargill, Incorporated | Fatty acid desaturases and mutant sequences thereof |
| EP0998484B1 (en) * | 1997-06-30 | 2004-03-03 | Glaxo Group Limited | Method of identifying compounds having reduced systemic effects |
| US6414223B1 (en) * | 1998-08-03 | 2002-07-02 | Cargill, Incorporated | Plants, seeds and oils having an elevated total monounsaturated fatty acid content |
| US6391298B1 (en) * | 1998-11-25 | 2002-05-21 | Bayer Corporation | Method of using PON-1 to decrease atheroma formation |
| JP2000333674A (ja) * | 1999-05-24 | 2000-12-05 | Bml Inc | パラオキソナーゼに対するモノクローナル抗体及びこれを用いる動脈硬化の判定方法 |
| US6573370B1 (en) | 2000-05-19 | 2003-06-03 | Regents Of The University Of Michigan | PON3 and uses thereof |
| US20020151068A1 (en) * | 2001-01-03 | 2002-10-17 | Board Of Regents, The University Of Texas System | Compositions and methods for the diagnosis and treatment of organophosphate toxicity |
| RU2255975C1 (ru) * | 2003-12-19 | 2005-07-10 | Химический факультет МГУ им. М.В. Ломоносова (Химфак МГУ) | Рекомбинантная плазмидная днк ptes-his-oph, кодирующая полипептид со свойствами органофосфатгидролазы, и штамм бактерий e.coli - продуцент полипептида со свойствами органофосфатгидролазы |
| CN1854300B (zh) * | 2005-04-29 | 2013-04-17 | 中国人民解放军军事医学科学院毒物药物研究所 | 含pon基因的重组质粒及其应用 |
| WO2008079185A2 (en) * | 2006-11-13 | 2008-07-03 | Ateris Technologies, Llc | Pesticide biomarker |
| KR20100109899A (ko) * | 2007-11-14 | 2010-10-11 | 아테리스 테크놀로지스, 엘엘씨 | 생물마커 탐지 |
| WO2013040501A1 (en) | 2011-09-16 | 2013-03-21 | Pharmathene, Inc. | Compositions and combinations of organophosphorus bioscavengers and hyaluronan-degrading enzymes, and uses thereof |
| CN108196064A (zh) * | 2017-12-26 | 2018-06-22 | 黑龙江八农垦大学 | 一种牛pon1蛋白的双抗夹心elisa检测试剂盒及检测方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5260203A (en) * | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5629193A (en) | 1994-07-05 | 1997-05-13 | Human Genome Sciences, Inc. | Paraoxonase |
-
1994
- 1994-07-05 US US08/270,583 patent/US5629193A/en not_active Expired - Lifetime
-
1995
- 1995-06-28 CN CN95193978A patent/CN1151760A/zh active Pending
- 1995-06-28 PT PT95925340T patent/PT804591E/pt unknown
- 1995-06-28 NZ NZ289607A patent/NZ289607A/xx not_active IP Right Cessation
- 1995-06-28 KR KR1019970700009A patent/KR970704887A/ko not_active Withdrawn
- 1995-06-28 EP EP95925340A patent/EP0804591B1/en not_active Expired - Lifetime
- 1995-06-28 WO PCT/US1995/008111 patent/WO1996001322A1/en not_active Ceased
- 1995-06-28 ES ES95925340T patent/ES2180648T3/es not_active Expired - Lifetime
- 1995-06-28 DE DE69528379T patent/DE69528379T2/de not_active Expired - Fee Related
- 1995-06-28 JP JP8503904A patent/JPH10502255A/ja not_active Ceased
- 1995-06-28 CA CA002194390A patent/CA2194390A1/en not_active Abandoned
- 1995-06-28 DK DK95925340T patent/DK0804591T3/da active
- 1995-06-28 AT AT95925340T patent/ATE224953T1/de not_active IP Right Cessation
- 1995-06-28 EP EP02000397A patent/EP1217007A2/en not_active Withdrawn
-
1997
- 1997-01-16 US US08/783,889 patent/US5792639A/en not_active Expired - Fee Related
-
1998
- 1998-04-27 US US09/067,089 patent/US6140093A/en not_active Expired - Fee Related
-
2002
- 2002-06-27 JP JP2002187866A patent/JP2003088364A/ja active Pending
-
2004
- 2004-09-02 US US10/932,269 patent/US7026140B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| PT804591E (pt) | 2002-12-31 |
| JPH10502255A (ja) | 1998-03-03 |
| DE69528379T2 (de) | 2003-06-12 |
| US5629193A (en) | 1997-05-13 |
| CN1151760A (zh) | 1997-06-11 |
| EP0804591B1 (en) | 2002-09-25 |
| EP1217007A2 (en) | 2002-06-26 |
| EP0804591A1 (en) | 1997-11-05 |
| US6140093A (en) | 2000-10-31 |
| CA2194390A1 (en) | 1996-01-18 |
| NZ289607A (en) | 1998-11-25 |
| DE69528379D1 (de) | 2002-10-31 |
| EP0804591A4 (en) | 1998-07-29 |
| KR970704887A (ko) | 1997-09-06 |
| ES2180648T3 (es) | 2003-02-16 |
| ATE224953T1 (de) | 2002-10-15 |
| WO1996001322A1 (en) | 1996-01-18 |
| US7026140B2 (en) | 2006-04-11 |
| US5792639A (en) | 1998-08-11 |
| JP2003088364A (ja) | 2003-03-25 |
| AU2950795A (en) | 1996-01-25 |
| US20050026226A1 (en) | 2005-02-03 |
| AU704834B2 (en) | 1999-05-06 |
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