DK0773924T3 - Fremgangsmåde til fremstilling af et dicarboxylsyredichlorid - Google Patents
Fremgangsmåde til fremstilling af et dicarboxylsyredichloridInfo
- Publication number
- DK0773924T3 DK0773924T3 DK96916098T DK96916098T DK0773924T3 DK 0773924 T3 DK0773924 T3 DK 0773924T3 DK 96916098 T DK96916098 T DK 96916098T DK 96916098 T DK96916098 T DK 96916098T DK 0773924 T3 DK0773924 T3 DK 0773924T3
- Authority
- DK
- Denmark
- Prior art keywords
- acid dichloride
- preparing
- dicarboxylic acid
- triiodo
- amino
- Prior art date
Links
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- DKPFZGUDAPQIHT-UHFFFAOYSA-N butyl acetate Chemical compound CCCCOC(C)=O DKPFZGUDAPQIHT-UHFFFAOYSA-N 0.000 abstract 2
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
- UOCLXMDMGBRAIB-UHFFFAOYSA-N 1,1,1-trichloroethane Chemical compound CC(Cl)(Cl)Cl UOCLXMDMGBRAIB-UHFFFAOYSA-N 0.000 abstract 1
- FBJVWRITWDYUAC-UHFFFAOYSA-N 5-amino-2,4,6-triiodobenzene-1,3-dicarbonyl chloride Chemical compound NC1=C(I)C(C(Cl)=O)=C(I)C(C(Cl)=O)=C1I FBJVWRITWDYUAC-UHFFFAOYSA-N 0.000 abstract 1
- JEZJSNULLBSYHV-UHFFFAOYSA-N 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid Chemical compound NC1=C(I)C(C(O)=O)=C(I)C(C(O)=O)=C1I JEZJSNULLBSYHV-UHFFFAOYSA-N 0.000 abstract 1
- 150000004945 aromatic hydrocarbons Chemical class 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- SBZXBUIDTXKZTM-UHFFFAOYSA-N diglyme Chemical compound COCCOCCOC SBZXBUIDTXKZTM-UHFFFAOYSA-N 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 150000002430 hydrocarbons Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 150000003512 tertiary amines Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C381/00—Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
- C07C381/10—Compounds containing sulfur atoms doubly-bound to nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI951044A IT1274546B (it) | 1995-05-23 | 1995-05-23 | Processo per la preparazione del dicloruro dell'acido 5-ammino-2,4,- 6-triiodoisoftalico |
IT95RM000550 IT1281320B1 (it) | 1995-08-04 | 1995-08-04 | Procedimento di preparazione di dicloruro dell'acido 5-ammino-2,4,6- triiodo-1,3-benzendicarbossilico per reazione dell'acido |
PCT/EP1996/002103 WO1996037459A1 (en) | 1995-05-23 | 1996-05-17 | Process for the preparation of a dicarboxylic acid dichloride |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0773924T3 true DK0773924T3 (da) | 1999-09-20 |
Family
ID=26331277
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK96916098T DK0773924T3 (da) | 1995-05-23 | 1996-05-17 | Fremgangsmåde til fremstilling af et dicarboxylsyredichlorid |
Country Status (22)
Country | Link |
---|---|
US (1) | US5616795A (de) |
EP (1) | EP0773924B1 (de) |
JP (1) | JP4012566B2 (de) |
KR (1) | KR100255914B1 (de) |
CN (1) | CN1157367C (de) |
AT (1) | ATE176663T1 (de) |
AU (1) | AU702895B2 (de) |
BR (1) | BR9606488A (de) |
CA (1) | CA2195636C (de) |
CZ (1) | CZ290345B6 (de) |
DE (2) | DE773924T1 (de) |
DK (1) | DK0773924T3 (de) |
ES (1) | ES2103252T3 (de) |
GR (1) | GR970300027T1 (de) |
HU (1) | HU216548B (de) |
IL (1) | IL118359A (de) |
MX (1) | MX9700548A (de) |
NO (1) | NO313696B1 (de) |
PL (1) | PL182447B1 (de) |
SI (1) | SI9620012A (de) |
SK (1) | SK8797A3 (de) |
WO (1) | WO1996037459A1 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1271107B (it) * | 1994-11-29 | 1997-05-26 | Zambon Spa | Processo per la preparazione di un intermedio utile nella sintesi di composti organici |
IT1292037B1 (it) * | 1997-05-30 | 1999-01-25 | Bracco Spa | Processo per la preparazione di 5-(acetil 62,3-diidrossipropil)- ammino)-n,n'-bis(2,3-diidrossipropil)-2,4,6-triiodo-1,3-benzen- |
EP1966110B1 (de) | 2005-12-19 | 2013-04-24 | Ge Healthcare As | Verfahren zur aufreinigung von iodixanol |
GB0717189D0 (en) * | 2007-09-04 | 2007-10-17 | Syngenta Participations Ag | Novel processes and compounds |
US8445725B2 (en) * | 2008-01-14 | 2013-05-21 | Mallinckrodt Llc | Process for the preparation of iosimenol |
EP2230227A1 (de) | 2009-03-20 | 2010-09-22 | Bracco Imaging S.p.A | Verfahren zur Herstellung von aromatischen Trijodid-Carboxyl- Derivaten |
EP2243767A1 (de) * | 2009-04-21 | 2010-10-27 | Bracco Imaging S.p.A | Verfahren zur Iodierung aromatischer Verbindungen |
US7999135B2 (en) | 2009-07-21 | 2011-08-16 | Ge Healthcare As | Crystallization of iodixanol using ultrasound |
US7999134B2 (en) | 2009-07-21 | 2011-08-16 | Ge Healthcare As | Crystallization of iodixanol using milling |
AU2009355814B2 (en) | 2009-11-26 | 2016-06-30 | Imax Diagnostic Imaging Holding Ltd | Preparation and purification of iodixanol |
EP2394984A1 (de) | 2010-06-10 | 2011-12-14 | Bracco Imaging S.p.A | Verfahren zur Iodinierung von Phenol-Derivaten |
CN111548268A (zh) | 2012-12-11 | 2020-08-18 | 伯拉考成像股份公司 | 制备(s)-2-乙酰氧基丙酰氯的连续方法 |
SI3369724T1 (sl) | 2013-11-05 | 2021-04-30 | Bracco Imaging Spa | Postopek za pripravo iopamidola |
MX2016015676A (es) | 2014-06-10 | 2017-02-27 | Bracco Imaging Spa | Metodo para la preparacion de acido (s)-2-acetiloxipropionico y derivados del mismo. |
CN104230731B (zh) * | 2014-09-24 | 2016-01-20 | 武汉理工大学 | 造影剂中间体三碘异酞酰氯的制备方法 |
CN110023279B (zh) | 2016-12-05 | 2022-03-11 | 伯拉考成像股份公司 | 放射照相剂中间体的机械化学合成 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH608189A5 (de) * | 1974-12-13 | 1978-12-29 | Savac Ag | |
IT1193211B (it) * | 1979-08-09 | 1988-06-15 | Bracco Ind Chimica Spa | Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono |
IT1207226B (it) * | 1979-08-09 | 1989-05-17 | Bracco Ind Chimica Spa | Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono. |
US4396598A (en) * | 1982-01-11 | 1983-08-02 | Mallinckrodt, Inc. | Triiodoisophthalamide X-ray contrast agent |
FR2541676A1 (fr) * | 1983-02-25 | 1984-08-31 | Guerbet Sa | Composes non-ioniques a structures benzenique iodee ou bromee et produits opacifiants en contenant |
US5075502A (en) * | 1989-12-13 | 1991-12-24 | Mallinckrodt, Inc. | Nonionic x-ray contrast agents, compositions and methods |
US5191120A (en) * | 1989-12-13 | 1993-03-02 | Mallinckrodt Medical, Inc. | Process for preparing nonionic X-ray contrast agents |
IT1271107B (it) * | 1994-11-29 | 1997-05-26 | Zambon Spa | Processo per la preparazione di un intermedio utile nella sintesi di composti organici |
-
1996
- 1996-05-17 JP JP53534596A patent/JP4012566B2/ja not_active Expired - Lifetime
- 1996-05-17 DE DE0773924T patent/DE773924T1/de active Pending
- 1996-05-17 KR KR1019970700402A patent/KR100255914B1/ko not_active IP Right Cessation
- 1996-05-17 DK DK96916098T patent/DK0773924T3/da active
- 1996-05-17 SI SI9620012A patent/SI9620012A/sl unknown
- 1996-05-17 BR BR9606488A patent/BR9606488A/pt not_active Application Discontinuation
- 1996-05-17 AT AT96916098T patent/ATE176663T1/de active
- 1996-05-17 WO PCT/EP1996/002103 patent/WO1996037459A1/en active IP Right Grant
- 1996-05-17 PL PL96318311A patent/PL182447B1/pl unknown
- 1996-05-17 HU HU9700188A patent/HU216548B/hu unknown
- 1996-05-17 CA CA002195636A patent/CA2195636C/en not_active Expired - Lifetime
- 1996-05-17 US US08/650,094 patent/US5616795A/en not_active Expired - Lifetime
- 1996-05-17 CN CNB961905271A patent/CN1157367C/zh not_active Expired - Lifetime
- 1996-05-17 DE DE69601525T patent/DE69601525T2/de not_active Expired - Lifetime
- 1996-05-17 ES ES96916098T patent/ES2103252T3/es not_active Expired - Lifetime
- 1996-05-17 AU AU58978/96A patent/AU702895B2/en not_active Expired
- 1996-05-17 MX MX9700548A patent/MX9700548A/es unknown
- 1996-05-17 EP EP96916098A patent/EP0773924B1/de not_active Expired - Lifetime
- 1996-05-17 SK SK87-97A patent/SK8797A3/sk unknown
- 1996-05-17 CZ CZ1997187A patent/CZ290345B6/cs not_active IP Right Cessation
- 1996-05-22 IL IL11835996A patent/IL118359A/xx not_active IP Right Cessation
-
1997
- 1997-01-21 NO NO19970261A patent/NO313696B1/no not_active IP Right Cessation
- 1997-09-30 GR GR970300027T patent/GR970300027T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0773924T3 (da) | Fremgangsmåde til fremstilling af et dicarboxylsyredichlorid | |
BR9809238A (pt) | Processo para a preparação de sais de ácido carboxìlico e catalisadores úteis em tal processo | |
IL118360A (en) | Process for the preparation of 5-amino-2,4,6, triiodo-1,3-benzene dicarboxylic acid | |
HUP9700190A1 (hu) | Eljárás dikarbonsav-diklorid előállítására, izolálására és tisztítására, és az előállított S-(-)-izomer | |
ZA9710862B (en) | A process for the preparation of 5-amino-2,4,6-triiodo-1,3-benzenedicarboxylic acid derivatives. | |
DE69722618D1 (en) | Peptide | |
DE69910609D1 (de) | Verfahren zur herstellung von n,n'-bis,2,3-dihydroxypropyl]-5-[(hydroxyacetyl)methylamino]-2,4,6-triiodo-1,3-benzenedicarboxamide | |
FI972261A0 (fi) | Menetelmä 5-amino-2,4,6-trijodi-isoftaalihappodikloridin valmistamiseksi klooraamalla vastaavaa happoa tertiäärisen amiinisuolan tai kvaternäärisen ammoniumsuolan läsnäollessa | |
DE19681399T1 (de) | Verfahren zur Herstellung von 5-Amino-2,4,6-triiodisophthalsäuredichlorid durch Chlorierung mit Thionylchlorid in Anwesenheit eines Katalysators | |
DE59308903D1 (de) | Aromatische Copolyamide, Verfahren zu ihrer Herstellung und daraus geformte Gebilde | |
IT1274546B (it) | Processo per la preparazione del dicloruro dell'acido 5-ammino-2,4,- 6-triiodoisoftalico | |
MX9700550A (es) | Procedimiento para la preparacion de un dicloruro de acido dicarboxilico. | |
TH21704A (th) | เพพไทด์ชนิดใหม่ที่มีผลปรับภูมิคุ้มกัน | |
ATE163917T1 (de) | Verfahren zur herstellung von sekundären aminen und in diesem verfahren zu verwendenden katalysator | |
TH21704B (th) | เพพไทด์ชนิดใหม่ที่มีผลปรับภูมิคุ้มกัน |