DK0767634T3 - Mikrokapsler til administration af neuroaktive midler - Google Patents
Mikrokapsler til administration af neuroaktive midlerInfo
- Publication number
- DK0767634T3 DK0767634T3 DK95924078T DK95924078T DK0767634T3 DK 0767634 T3 DK0767634 T3 DK 0767634T3 DK 95924078 T DK95924078 T DK 95924078T DK 95924078 T DK95924078 T DK 95924078T DK 0767634 T3 DK0767634 T3 DK 0767634T3
- Authority
- DK
- Denmark
- Prior art keywords
- mum
- microspheres
- microcapsules
- administration
- nervous system
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0085—Brain, e.g. brain implants; Spinal cord
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
- A61K9/5068—Cell membranes or bacterial membranes enclosing drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
- Y10S977/907—Liposome
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Molecular Biology (AREA)
- Botany (AREA)
- Zoology (AREA)
- Virology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/268,177 US6517859B1 (en) | 1990-05-16 | 1994-06-29 | Microcapsules for administration of neuroactive agents |
PCT/US1995/008123 WO1996000537A1 (en) | 1994-06-29 | 1995-06-28 | Microcapsules for administration of neuroactive agents |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0767634T3 true DK0767634T3 (da) | 2004-07-19 |
Family
ID=23021810
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK95924078T DK0767634T3 (da) | 1994-06-29 | 1995-06-28 | Mikrokapsler til administration af neuroaktive midler |
Country Status (8)
Country | Link |
---|---|
US (2) | US6517859B1 (da) |
EP (1) | EP0767634B1 (da) |
JP (1) | JPH10506373A (da) |
AT (1) | ATE261278T1 (da) |
DE (1) | DE69532673T2 (da) |
DK (1) | DK0767634T3 (da) |
ES (1) | ES2217281T3 (da) |
WO (1) | WO1996000537A1 (da) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5827819A (en) * | 1990-11-01 | 1998-10-27 | Oregon Health Sciences University | Covalent polar lipid conjugates with neurologically active compounds for targeting |
US5543390A (en) | 1990-11-01 | 1996-08-06 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University | Covalent microparticle-drug conjugates for biological targeting |
US6123956A (en) * | 1997-07-10 | 2000-09-26 | Keith Baker | Methods for universally distributing therapeutic agents to the brain |
US7045543B2 (en) | 2001-11-05 | 2006-05-16 | Enzrel Inc. | Covalent conjugates of biologically-active compounds with amino acids and amino acid derivatives for targeting to physiologically-protected sites |
US7378111B2 (en) * | 2002-02-20 | 2008-05-27 | The Trustees Of The University Of Pennsylvania | Regulation of GSK-3α activity for the treatment or prevention of Alzheimer's disease |
US20080121141A1 (en) * | 2006-11-16 | 2008-05-29 | Haggquist Gregory W | Exothermic-enhanced articles and methods for making the same |
EP2286893B1 (en) * | 2002-06-12 | 2013-06-05 | Cocona, Inc. | Encapsulated active particles and methods for making and using the same |
PL1610791T3 (pl) | 2003-03-31 | 2011-07-29 | Titan Pharmaceuticals Inc | Wszczepialne urządzenie polimerowe do przedłużonego uwalniania agonisty dopaminy |
WO2005095950A1 (en) * | 2004-03-30 | 2005-10-13 | Pfizer Products Inc. | Method and device for evaluation of pharmaceutical compositions |
CA2592320C (en) | 2004-12-22 | 2015-11-24 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
WO2006097725A2 (en) * | 2005-03-15 | 2006-09-21 | Queen Mary & Westfield College | Pharmaceutical compositions comprising microparticles for delivery into neurons |
US7846445B2 (en) * | 2005-09-27 | 2010-12-07 | Amunix Operating, Inc. | Methods for production of unstructured recombinant polymers and uses thereof |
US7855279B2 (en) * | 2005-09-27 | 2010-12-21 | Amunix Operating, Inc. | Unstructured recombinant polymers and uses thereof |
US20070191272A1 (en) * | 2005-09-27 | 2007-08-16 | Stemmer Willem P | Proteinaceous pharmaceuticals and uses thereof |
US20090099031A1 (en) * | 2005-09-27 | 2009-04-16 | Stemmer Willem P | Genetic package and uses thereof |
US20070142287A1 (en) * | 2005-12-20 | 2007-06-21 | Biomed Solutions, Llc | Compositions And Methods For Treatment Of Cancer |
US20070190127A1 (en) | 2005-12-30 | 2007-08-16 | Mingdong Zhou | Extended release of neuregulin for improved cardiac function |
US20070231360A1 (en) * | 2006-03-28 | 2007-10-04 | Minu, L.L.C. | Neural conduit agent dissemination |
EP2520611B1 (en) * | 2006-05-09 | 2017-06-21 | Cocona, Inc. | Method for producing a water-proof breathable membrane |
CA2666246C (en) | 2006-10-12 | 2013-12-31 | Bellus Health (International) Limited | Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid |
WO2008065502A1 (en) * | 2006-11-29 | 2008-06-05 | Pfizer Products Inc. | Pharmaceutical compositions based on a) nanoparticles comprising enteric polymers and b) casein |
WO2008122044A2 (en) * | 2007-04-02 | 2008-10-09 | Georgia Tech Research Corporation | Implantable device for communicating with biological tissue |
WO2008125940A2 (en) * | 2007-04-17 | 2008-10-23 | Pfizer Products Inc. | Nanoparticles comprising non-crystalline drug |
WO2008135828A2 (en) | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Nanoparticles comprising a drug, ethylcellulose, and a bile salt |
US20100080852A1 (en) * | 2007-05-03 | 2010-04-01 | Ronald Arthur Beyerinck | Phamaceutical composition comprising nanoparticles and casein |
WO2008135855A2 (en) * | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and a nonionizable polymer |
US9545384B2 (en) | 2007-06-04 | 2017-01-17 | Bend Research, Inc. | Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glocol succinate |
WO2008149192A2 (en) * | 2007-06-04 | 2008-12-11 | Pfizer Products Inc. | Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer |
WO2009010842A2 (en) * | 2007-07-13 | 2009-01-22 | Pfizer Products Inc. | Nanoparticles comprising ionizable, poorly water soluble cellulosic polymers |
KR20100058541A (ko) * | 2007-08-15 | 2010-06-03 | 아뮤닉스 인코포레이티드 | 생물학적 활성 폴리펩티드의 특성을 변경하기 위한 조성물 및 방법 |
WO2009073215A1 (en) * | 2007-12-06 | 2009-06-11 | Bend Research, Inc. | Pharmaceutical compositions comprising nanoparticles and a resuspending material |
EP2240162A4 (en) * | 2007-12-06 | 2013-10-09 | Bend Res Inc | NANOTE PARTICLES WITH A NON-IONIZABLE POLYMER AND AN AMIN-FUNCTIONALIZED METHACRYLATE COPOLYMER |
CA2736729A1 (en) | 2008-09-29 | 2010-04-01 | Ben Gurion University Of The Negev Research And Development Authority | Amyloid beta-peptides and methods of use thereof |
ES2730800T3 (es) * | 2009-02-03 | 2019-11-12 | Amunix Pharmaceuticals Inc | Polipéptidos recombinantes extendidos y composiciones que comprenden los mismos |
AU2010290131C1 (en) | 2009-08-24 | 2015-12-03 | Amunix Operating Inc. | Coagulation factor VII compositions and methods of making and using same |
AU2010313456A1 (en) | 2009-10-30 | 2012-05-17 | Ntf Therapeutics, Inc. | Improved neurturin molecules |
SI3564260T1 (sl) | 2012-02-15 | 2023-02-28 | Bioverativ Therapeutics Inc. | Sestavki faktorja VIII in postopki njegove izdelave in uporabe |
CA2864126A1 (en) | 2012-02-15 | 2013-08-22 | Biogen Idec Ma Inc. | Recombinant factor viii proteins |
EP3033097B1 (en) | 2013-08-14 | 2021-03-10 | Bioverativ Therapeutics Inc. | Factor viii-xten fusions and uses thereof |
CN108472337B (zh) | 2015-08-03 | 2022-11-25 | 比奥贝拉蒂治疗公司 | 因子ix融合蛋白以及其制备和使用方法 |
CN106519205B (zh) * | 2016-10-26 | 2018-04-10 | 河南工程学院 | 一种载药多孔phbv接枝多巴胺微球的制备方法及应用 |
DK3576771T3 (da) | 2017-01-31 | 2022-05-30 | Veru Inc | Sammensætninger og fremgangsmåder til langvarig frigivelse af antagonister for gonadotropin-frigivende hormon (gnrh) |
CN110997693A (zh) | 2017-06-07 | 2020-04-10 | 阿德克斯公司 | τ聚集抑制剂 |
EP3668886A2 (en) | 2017-08-18 | 2020-06-24 | Adrx, Inc. | Tau aggregation peptide inhibitors |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE52535B1 (en) | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
JPS6048923A (ja) | 1983-08-25 | 1985-03-16 | Mitsui Toatsu Chem Inc | 微小粒子の製造方法 |
JPS60100516A (ja) | 1983-11-04 | 1985-06-04 | Takeda Chem Ind Ltd | 徐放型マイクロカプセルの製造法 |
US4962091A (en) * | 1986-05-23 | 1990-10-09 | Syntex (U.S.A.) Inc. | Controlled release of macromolecular polypeptides |
US4832686A (en) | 1986-06-24 | 1989-05-23 | Anderson Mark E | Method for administering interleukin-2 |
JPS63122620A (ja) * | 1986-11-12 | 1988-05-26 | Sanraku Inc | ポリ乳酸マイクロスフエア及びその製造方法 |
US4883666A (en) * | 1987-04-29 | 1989-11-28 | Massachusetts Institute Of Technology | Controlled drug delivery system for treatment of neural disorders |
US4882686A (en) * | 1987-06-22 | 1989-11-21 | Eastman Kodak Company | Printing apparatus with improved data formatting circuitry |
IL92344A0 (en) | 1989-01-04 | 1990-07-26 | Gist Brocades Nv | Microencapsulation of bioactive substances in biocompatible polymers,microcapsules obtained and pharmaceutical preparation comprising said microcapsules |
DK0478671T3 (da) | 1989-06-21 | 1993-10-18 | Univ Brown Res Found | Neurologisk terapeutisk anordning |
CH679207A5 (da) | 1989-07-28 | 1992-01-15 | Debiopharm Sa | |
US5225205A (en) | 1989-07-28 | 1993-07-06 | Debiopharm S.A. | Pharmaceutical composition in the form of microparticles |
JP3187410B2 (ja) | 1989-08-10 | 2001-07-11 | 住友製薬株式会社 | 脳内投与用徐放性製剤 |
JP3359919B2 (ja) | 1990-05-16 | 2002-12-24 | サザン・リサーチ・インスティテュート | 放出制御ドーパミンおよび神経線維成長を刺激するための用途 |
-
1994
- 1994-06-29 US US08/268,177 patent/US6517859B1/en not_active Expired - Fee Related
-
1995
- 1995-06-28 ES ES95924078T patent/ES2217281T3/es not_active Expired - Lifetime
- 1995-06-28 AT AT95924078T patent/ATE261278T1/de not_active IP Right Cessation
- 1995-06-28 WO PCT/US1995/008123 patent/WO1996000537A1/en active IP Right Grant
- 1995-06-28 EP EP95924078A patent/EP0767634B1/en not_active Expired - Lifetime
- 1995-06-28 DE DE69532673T patent/DE69532673T2/de not_active Expired - Fee Related
- 1995-06-28 DK DK95924078T patent/DK0767634T3/da active
- 1995-06-28 JP JP8503413A patent/JPH10506373A/ja not_active Ceased
-
2001
- 2001-08-21 US US09/934,382 patent/US6565875B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US6565875B2 (en) | 2003-05-20 |
EP0767634B1 (en) | 2004-03-10 |
ATE261278T1 (de) | 2004-03-15 |
JPH10506373A (ja) | 1998-06-23 |
EP0767634A1 (en) | 1997-04-16 |
WO1996000537A1 (en) | 1996-01-11 |
EP0767634A4 (en) | 1998-09-30 |
DE69532673T2 (de) | 2005-02-17 |
DE69532673D1 (de) | 2004-04-15 |
US6517859B1 (en) | 2003-02-11 |
ES2217281T3 (es) | 2004-11-01 |
US20020094347A1 (en) | 2002-07-18 |
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