DK0756489T3 - Cyclosporinholdigt præparat og fremgangsmåde til fremstillingen af dette - Google Patents

Cyclosporinholdigt præparat og fremgangsmåde til fremstillingen af dette

Info

Publication number
DK0756489T3
DK0756489T3 DK95920275T DK95920275T DK0756489T3 DK 0756489 T3 DK0756489 T3 DK 0756489T3 DK 95920275 T DK95920275 T DK 95920275T DK 95920275 T DK95920275 T DK 95920275T DK 0756489 T3 DK0756489 T3 DK 0756489T3
Authority
DK
Denmark
Prior art keywords
pct
preparation
cyclosporin
sec
composition
Prior art date
Application number
DK95920275T
Other languages
Danish (da)
English (en)
Inventor
Hyun Soo Kim
Jae Yoon Choi
Hye Weon Lee
Young Keun Park
Sung Wook Choi
Original Assignee
Yuhan Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yuhan Corp filed Critical Yuhan Corp
Application granted granted Critical
Publication of DK0756489T3 publication Critical patent/DK0756489T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Cosmetics (AREA)
DK95920275T 1994-06-01 1995-05-19 Cyclosporinholdigt præparat og fremgangsmåde til fremstillingen af dette DK0756489T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR19940012288 1994-06-01
PCT/KR1995/000059 WO1995032726A1 (en) 1994-06-01 1995-05-19 Cyclosporin containing composition and process for the preparation thereof

Publications (1)

Publication Number Publication Date
DK0756489T3 true DK0756489T3 (da) 1999-12-06

Family

ID=19384450

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95920275T DK0756489T3 (da) 1994-06-01 1995-05-19 Cyclosporinholdigt præparat og fremgangsmåde til fremstillingen af dette

Country Status (13)

Country Link
US (1) US5739105A (zh)
EP (1) EP0756489B1 (zh)
JP (1) JP2936209B2 (zh)
KR (1) KR0163212B1 (zh)
CN (1) CN1148224C (zh)
AT (1) ATE183398T1 (zh)
AU (1) AU2577295A (zh)
DE (1) DE69511539T2 (zh)
DK (1) DK0756489T3 (zh)
ES (1) ES2137516T3 (zh)
GR (1) GR3031568T3 (zh)
RU (1) RU2119351C1 (zh)
WO (1) WO1995032726A1 (zh)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9618952D0 (en) * 1996-09-11 1996-10-23 Sandoz Ltd Process
KR100241652B1 (ko) * 1997-07-07 2000-03-02 김충섭 이푸리플라본의 경구 투여용 제제의 제조 방법
EP1023441A1 (en) 1997-10-16 2000-08-02 The Board Of Regents, The University Of Texas System Models and treatments for cardiac hypertrophy in relation with nf-at3 function
TW581681B (en) * 1998-02-20 2004-04-01 Nektar Therapeutics Liquid crystal forms of cyclosporin
WO2000040219A1 (en) 1998-12-30 2000-07-13 Dexcel Ltd. Dispersible concentrate for the delivery of cyclosporin
WO2000040220A1 (en) * 1999-01-06 2000-07-13 Korea Research Institute Of Chemical Technology Method of preparing pharmaceutical active ingredient comprising water-insoluble drug and pharmaceutical composition for oral administration comprising the same
US7732404B2 (en) * 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
DK1142566T3 (da) * 2000-04-07 2004-02-09 Medidom Lab Oftalmologiske formuleringer på basis af ciclosporin, hyaluronsyre og polysorbat
GB0008785D0 (en) * 2000-04-10 2000-05-31 Novartis Ag Organic compounds
EP2116228A1 (en) * 2001-10-19 2009-11-11 Isotechnika Inc. Novel cyclosporin analog microemulsion preconcentrates
US6979672B2 (en) * 2002-12-20 2005-12-27 Polichem, S.A. Cyclosporin-based pharmaceutical compositions
US20050059583A1 (en) 2003-09-15 2005-03-17 Allergan, Inc. Methods of providing therapeutic effects using cyclosporin components
DE602004017477D1 (de) * 2004-11-09 2008-12-11 Novagali Pharma Sa Öl-in-Wasser-Emulsion mit niedriger Konzentration des kationischen Mittels und positivem Zetapotential
US7151085B2 (en) * 2004-11-15 2006-12-19 Allergan, Inc. Therapeutic methods using cyclosporine components
US7135455B2 (en) * 2004-11-15 2006-11-14 Allergan, Inc Methods for the therapeutic use of cyclosporine components
WO2006083913A2 (en) 2005-02-02 2006-08-10 össur hf Sensing systems and methods for monitoring gait dynamics
GB0921528D0 (en) 2009-12-09 2010-01-27 Mast Carbon Internat Ltd Carbon and its use in blood cleansing applications
JP6200698B2 (ja) * 2013-06-18 2017-09-20 ニュートリー株式会社 嚥下造影検査食
JP2023548965A (ja) * 2020-11-09 2023-11-21 スカイ・セラピューティクス・カンパニー・リミテッド 固相の物質及びこれを含む分散組成物
JP2023548966A (ja) * 2020-11-09 2023-11-21 スカイ・セラピューティクス・カンパニー・リミテッド 固相のシクロスポリンａ及びこれを含む分散組成物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8807505D0 (en) * 1988-03-29 1988-05-05 Glaxo Group Ltd Pharmaceutical combinations

Also Published As

Publication number Publication date
ATE183398T1 (de) 1999-09-15
JPH09510733A (ja) 1997-10-28
DE69511539D1 (de) 1999-09-23
KR0163212B1 (ko) 1998-12-01
US5739105A (en) 1998-04-14
RU2119351C1 (ru) 1998-09-27
EP0756489B1 (en) 1999-08-18
GR3031568T3 (en) 2000-01-31
CN1149834A (zh) 1997-05-14
ES2137516T3 (es) 1999-12-16
CN1148224C (zh) 2004-05-05
AU2577295A (en) 1995-12-21
KR960000247A (ko) 1996-01-25
EP0756489A1 (en) 1997-02-05
DE69511539T2 (de) 2000-03-30
JP2936209B2 (ja) 1999-08-23
WO1995032726A1 (en) 1995-12-07

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