DK0746556T3 - Tricycliske forbindelser med affinitet for 5-HT1A-receptoren - Google Patents

Tricycliske forbindelser med affinitet for 5-HT1A-receptoren

Info

Publication number
DK0746556T3
DK0746556T3 DK94930720T DK94930720T DK0746556T3 DK 0746556 T3 DK0746556 T3 DK 0746556T3 DK 94930720 T DK94930720 T DK 94930720T DK 94930720 T DK94930720 T DK 94930720T DK 0746556 T3 DK0746556 T3 DK 0746556T3
Authority
DK
Denmark
Prior art keywords
affinity
tricyclic compounds
ht1a receptor
ht1a
receptor
Prior art date
Application number
DK94930720T
Other languages
Danish (da)
English (en)
Inventor
Allen B Reitz
Ellen W Baxter
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Application granted granted Critical
Publication of DK0746556T3 publication Critical patent/DK0746556T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
DK94930720T 1993-10-25 1994-10-11 Tricycliske forbindelser med affinitet for 5-HT1A-receptoren DK0746556T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/142,748 US5512566A (en) 1993-10-25 1993-10-25 Tricyclic compounds having affinity for the 5-HT1A receptor
PCT/US1994/011544 WO1995011903A1 (en) 1993-10-25 1994-10-11 Tricyclic compounds having affinity for the 5-ht1a receptor

Publications (1)

Publication Number Publication Date
DK0746556T3 true DK0746556T3 (da) 2002-12-16

Family

ID=22501119

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94930720T DK0746556T3 (da) 1993-10-25 1994-10-11 Tricycliske forbindelser med affinitet for 5-HT1A-receptoren

Country Status (15)

Country Link
US (1) US5512566A (ja)
EP (1) EP0746556B1 (ja)
JP (1) JP3709203B2 (ja)
AT (1) ATE224895T1 (ja)
AU (1) AU680562B2 (ja)
CA (1) CA2174850A1 (ja)
DE (1) DE69431441T2 (ja)
DK (1) DK0746556T3 (ja)
ES (1) ES2183843T3 (ja)
IL (1) IL111246A (ja)
NZ (1) NZ275689A (ja)
PT (1) PT746556E (ja)
SI (1) SI0746556T1 (ja)
WO (1) WO1995011903A1 (ja)
ZA (1) ZA948354B (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688950A (en) * 1996-04-23 1997-11-18 Neurogen Corporation Tricyclic aminoalkylcarboxamides; novel dopamine D3 receptor subtype specific ligands

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3755584A (en) * 1972-04-03 1973-08-28 Abbott Lab Tranquilizers
IT1052009B (it) * 1975-12-30 1981-06-20 Erba Carlo Spa Imidazo 4.3 c 1.4 benzossazino imidazo 4.3 c 1.4 benzotiazino pirazo 2.1 c 1.4 benzossazino e pirazo 2.1 c 1.4 benzotiazino derivati
US5049564A (en) * 1989-11-17 1991-09-17 Abbott Laboratories 5-HT selective agents
AU626621B2 (en) * 1988-12-15 1992-08-06 Abbott Laboratories Substituted hexahydro-indenopyrroles, -indenopyridines, and -benzoisoindoles as 5-ht selective agents
US5244888A (en) * 1989-11-17 1993-09-14 Abbott Laboratories 5-HT selective agents
EP0510068B1 (en) * 1990-01-11 1999-04-14 PHARMACIA & UPJOHN COMPANY NEW CENTRALLY ACTING 6,7,8,9-TETRAHYDRO-3H-BENZ(e)INDOLE HETEROCYCLICS
AU639536B2 (en) * 1990-03-15 1993-07-29 Pharmacia & Upjohn Company Therapeutically useful heterocyclic indole compounds
CA2118920A1 (en) * 1991-10-24 1993-04-29 Arthur G. Romero Benzo-isoquinoline derivatives and analogs and their use in therapeutics
EP0539209A1 (en) * 1991-10-24 1993-04-28 The Upjohn Company Benzo-isoquinoline derivatives and analogs and their use in therapeutics

Also Published As

Publication number Publication date
IL111246A0 (en) 1994-12-29
ZA948354B (en) 1996-04-24
IL111246A (en) 1998-01-04
PT746556E (pt) 2002-12-31
JPH09504789A (ja) 1997-05-13
AU680562B2 (en) 1997-07-31
US5512566A (en) 1996-04-30
DE69431441T2 (de) 2003-10-23
DE69431441D1 (de) 2002-10-31
AU7975794A (en) 1995-05-22
SI0746556T1 (en) 2003-02-28
ES2183843T3 (es) 2003-04-01
EP0746556B1 (en) 2002-09-25
EP0746556A1 (en) 1996-12-11
JP3709203B2 (ja) 2005-10-26
WO1995011903A1 (en) 1995-05-04
ATE224895T1 (de) 2002-10-15
NZ275689A (en) 1997-12-19
CA2174850A1 (en) 1995-05-04

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