PT746556E - Compostos triciclicos com afinidade para o receptor 5-ht1a - Google Patents

Compostos triciclicos com afinidade para o receptor 5-ht1a

Info

Publication number
PT746556E
PT746556E PT94930720T PT94930720T PT746556E PT 746556 E PT746556 E PT 746556E PT 94930720 T PT94930720 T PT 94930720T PT 94930720 T PT94930720 T PT 94930720T PT 746556 E PT746556 E PT 746556E
Authority
PT
Portugal
Prior art keywords
compounds
atricyric
affinity
ht1a receptor
ht1a
Prior art date
Application number
PT94930720T
Other languages
English (en)
Inventor
Ellen W Baxter
Allen B Reitz
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of PT746556E publication Critical patent/PT746556E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT94930720T 1993-10-25 1994-10-11 Compostos triciclicos com afinidade para o receptor 5-ht1a PT746556E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/142,748 US5512566A (en) 1993-10-25 1993-10-25 Tricyclic compounds having affinity for the 5-HT1A receptor

Publications (1)

Publication Number Publication Date
PT746556E true PT746556E (pt) 2002-12-31

Family

ID=22501119

Family Applications (1)

Application Number Title Priority Date Filing Date
PT94930720T PT746556E (pt) 1993-10-25 1994-10-11 Compostos triciclicos com afinidade para o receptor 5-ht1a

Country Status (15)

Country Link
US (1) US5512566A (pt)
EP (1) EP0746556B1 (pt)
JP (1) JP3709203B2 (pt)
AT (1) ATE224895T1 (pt)
AU (1) AU680562B2 (pt)
CA (1) CA2174850A1 (pt)
DE (1) DE69431441T2 (pt)
DK (1) DK0746556T3 (pt)
ES (1) ES2183843T3 (pt)
IL (1) IL111246A (pt)
NZ (1) NZ275689A (pt)
PT (1) PT746556E (pt)
SI (1) SI0746556T1 (pt)
WO (1) WO1995011903A1 (pt)
ZA (1) ZA948354B (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688950A (en) * 1996-04-23 1997-11-18 Neurogen Corporation Tricyclic aminoalkylcarboxamides; novel dopamine D3 receptor subtype specific ligands

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3755584A (en) * 1972-04-03 1973-08-28 Abbott Lab Tranquilizers
IT1052009B (it) * 1975-12-30 1981-06-20 Erba Carlo Spa Imidazo 4.3 c 1.4 benzossazino imidazo 4.3 c 1.4 benzotiazino pirazo 2.1 c 1.4 benzossazino e pirazo 2.1 c 1.4 benzotiazino derivati
ATE139230T1 (de) * 1988-12-15 1996-06-15 Abbott Lab 5-ht-selektive mittel
US5049564A (en) * 1989-11-17 1991-09-17 Abbott Laboratories 5-HT selective agents
US5244888A (en) * 1989-11-17 1993-09-14 Abbott Laboratories 5-HT selective agents
ES2130135T3 (es) * 1990-01-11 1999-07-01 Upjohn Co Nuevos compuestos heterociclicos de 6,7,8,9-tetrahidro-3h-benz(e)indol con actividad terapeutica sobre el sistema nervioso central.
WO1991013872A1 (en) * 1990-03-15 1991-09-19 The Upjohn Company Therapeutically useful heterocyclic indole compounds
EP0539209A1 (en) * 1991-10-24 1993-04-28 The Upjohn Company Benzo-isoquinoline derivatives and analogs and their use in therapeutics
WO1993008166A1 (en) * 1991-10-24 1993-04-29 The Upjohn Company Benzo-isoquinoline derivatives and analogs and their use in therapeutics

Also Published As

Publication number Publication date
IL111246A0 (en) 1994-12-29
EP0746556B1 (en) 2002-09-25
ZA948354B (en) 1996-04-24
DE69431441T2 (de) 2003-10-23
US5512566A (en) 1996-04-30
ES2183843T3 (es) 2003-04-01
JPH09504789A (ja) 1997-05-13
ATE224895T1 (de) 2002-10-15
AU7975794A (en) 1995-05-22
DK0746556T3 (da) 2002-12-16
NZ275689A (en) 1997-12-19
CA2174850A1 (en) 1995-05-04
DE69431441D1 (de) 2002-10-31
JP3709203B2 (ja) 2005-10-26
EP0746556A1 (en) 1996-12-11
SI0746556T1 (en) 2003-02-28
AU680562B2 (en) 1997-07-31
IL111246A (en) 1998-01-04
WO1995011903A1 (en) 1995-05-04

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