SI0746556T1 - Tricyclic compounds having affinity for the 5-ht1a receptor - Google Patents

Tricyclic compounds having affinity for the 5-ht1a receptor

Info

Publication number
SI0746556T1
SI0746556T1 SI9430418T SI9430418T SI0746556T1 SI 0746556 T1 SI0746556 T1 SI 0746556T1 SI 9430418 T SI9430418 T SI 9430418T SI 9430418 T SI9430418 T SI 9430418T SI 0746556 T1 SI0746556 T1 SI 0746556T1
Authority
SI
Slovenia
Prior art keywords
affinity
tricyclic compounds
ht1a receptor
ht1a
receptor
Prior art date
Application number
SI9430418T
Other languages
English (en)
Slovenian (sl)
Inventor
Ellen W. Baxter
Allen B. Reitz
Original Assignee
Ortho-Mcneil Pharmaceutical, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho-Mcneil Pharmaceutical, Inc. filed Critical Ortho-Mcneil Pharmaceutical, Inc.
Publication of SI0746556T1 publication Critical patent/SI0746556T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
SI9430418T 1993-10-25 1994-10-11 Tricyclic compounds having affinity for the 5-ht1a receptor SI0746556T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/142,748 US5512566A (en) 1993-10-25 1993-10-25 Tricyclic compounds having affinity for the 5-HT1A receptor
PCT/US1994/011544 WO1995011903A1 (en) 1993-10-25 1994-10-11 Tricyclic compounds having affinity for the 5-ht1a receptor
EP94930720A EP0746556B1 (en) 1993-10-25 1994-10-11 Tricyclic compounds having affinity for the 5-ht1a receptor

Publications (1)

Publication Number Publication Date
SI0746556T1 true SI0746556T1 (en) 2003-02-28

Family

ID=22501119

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9430418T SI0746556T1 (en) 1993-10-25 1994-10-11 Tricyclic compounds having affinity for the 5-ht1a receptor

Country Status (15)

Country Link
US (1) US5512566A (ja)
EP (1) EP0746556B1 (ja)
JP (1) JP3709203B2 (ja)
AT (1) ATE224895T1 (ja)
AU (1) AU680562B2 (ja)
CA (1) CA2174850A1 (ja)
DE (1) DE69431441T2 (ja)
DK (1) DK0746556T3 (ja)
ES (1) ES2183843T3 (ja)
IL (1) IL111246A (ja)
NZ (1) NZ275689A (ja)
PT (1) PT746556E (ja)
SI (1) SI0746556T1 (ja)
WO (1) WO1995011903A1 (ja)
ZA (1) ZA948354B (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688950A (en) * 1996-04-23 1997-11-18 Neurogen Corporation Tricyclic aminoalkylcarboxamides; novel dopamine D3 receptor subtype specific ligands

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3755584A (en) * 1972-04-03 1973-08-28 Abbott Lab Tranquilizers
IT1052009B (it) * 1975-12-30 1981-06-20 Erba Carlo Spa Imidazo 4.3 c 1.4 benzossazino imidazo 4.3 c 1.4 benzotiazino pirazo 2.1 c 1.4 benzossazino e pirazo 2.1 c 1.4 benzotiazino derivati
US5049564A (en) * 1989-11-17 1991-09-17 Abbott Laboratories 5-HT selective agents
AU626621B2 (en) * 1988-12-15 1992-08-06 Abbott Laboratories Substituted hexahydro-indenopyrroles, -indenopyridines, and -benzoisoindoles as 5-ht selective agents
US5244888A (en) * 1989-11-17 1993-09-14 Abbott Laboratories 5-HT selective agents
EP0510068B1 (en) * 1990-01-11 1999-04-14 PHARMACIA & UPJOHN COMPANY NEW CENTRALLY ACTING 6,7,8,9-TETRAHYDRO-3H-BENZ(e)INDOLE HETEROCYCLICS
AU639536B2 (en) * 1990-03-15 1993-07-29 Pharmacia & Upjohn Company Therapeutically useful heterocyclic indole compounds
CA2118920A1 (en) * 1991-10-24 1993-04-29 Arthur G. Romero Benzo-isoquinoline derivatives and analogs and their use in therapeutics
EP0539209A1 (en) * 1991-10-24 1993-04-28 The Upjohn Company Benzo-isoquinoline derivatives and analogs and their use in therapeutics

Also Published As

Publication number Publication date
IL111246A0 (en) 1994-12-29
ZA948354B (en) 1996-04-24
IL111246A (en) 1998-01-04
PT746556E (pt) 2002-12-31
JPH09504789A (ja) 1997-05-13
AU680562B2 (en) 1997-07-31
US5512566A (en) 1996-04-30
DK0746556T3 (da) 2002-12-16
DE69431441T2 (de) 2003-10-23
DE69431441D1 (de) 2002-10-31
AU7975794A (en) 1995-05-22
ES2183843T3 (es) 2003-04-01
EP0746556B1 (en) 2002-09-25
EP0746556A1 (en) 1996-12-11
JP3709203B2 (ja) 2005-10-26
WO1995011903A1 (en) 1995-05-04
ATE224895T1 (de) 2002-10-15
NZ275689A (en) 1997-12-19
CA2174850A1 (en) 1995-05-04

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