DK0714908T3 - Nye 17-(3-imino-2-alkylproenyl)-5beta, 14beta-androstanderivater, der er aktive i det cardiovaskulære system, fremgansmåder - Google Patents

Nye 17-(3-imino-2-alkylproenyl)-5beta, 14beta-androstanderivater, der er aktive i det cardiovaskulære system, fremgansmåder

Info

Publication number
DK0714908T3
DK0714908T3 DK95117347T DK95117347T DK0714908T3 DK 0714908 T3 DK0714908 T3 DK 0714908T3 DK 95117347 T DK95117347 T DK 95117347T DK 95117347 T DK95117347 T DK 95117347T DK 0714908 T3 DK0714908 T3 DK 0714908T3
Authority
DK
Denmark
Prior art keywords
imino
alkylproenyl
14beta
5beta
new
Prior art date
Application number
DK95117347T
Other languages
English (en)
Inventor
Piero Melloni
Alberto Cerri
Giuseppe Bianchi
Patrizia Ferrari
Maria L Quadri
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Application granted granted Critical
Publication of DK0714908T3 publication Critical patent/DK0714908T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DK95117347T 1994-11-29 1995-11-03 Nye 17-(3-imino-2-alkylproenyl)-5beta, 14beta-androstanderivater, der er aktive i det cardiovaskulære system, fremgansmåder DK0714908T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4442486A DE4442486A1 (de) 1994-11-29 1994-11-29 Neue 17-(3-Imino-2-alkylpropylen)-5ß,14ß-androstan-Derivate, die auf das kardiovaskuläre System wirken, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen

Publications (1)

Publication Number Publication Date
DK0714908T3 true DK0714908T3 (da) 1998-09-28

Family

ID=6534459

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95117347T DK0714908T3 (da) 1994-11-29 1995-11-03 Nye 17-(3-imino-2-alkylproenyl)-5beta, 14beta-androstanderivater, der er aktive i det cardiovaskulære system, fremgansmåder

Country Status (9)

Country Link
US (1) US5705662A (da)
EP (1) EP0714908B1 (da)
JP (1) JP3899136B2 (da)
AT (1) ATE163424T1 (da)
CA (1) CA2163935C (da)
DE (2) DE4442486A1 (da)
DK (1) DK0714908T3 (da)
ES (1) ES2112597T3 (da)
HK (1) HK1009334A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030083231A1 (en) * 1998-11-24 2003-05-01 Ahlem Clarence N. Blood cell deficiency treatment method
US6764817B1 (en) * 1999-04-20 2004-07-20 Target Discovery, Inc. Methods for conducting metabolic analyses

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4222404C1 (de) * 1992-07-08 1993-12-02 Sigma Tau Ind Farmaceuti Verwendung von Iminoderivaten von Etianaldehyd zur Behandlung von Hypertonie
DE4227605C2 (de) * 1992-08-20 1995-02-16 Sigma Tau Ind Farmaceuti 17-Hydroxyiminomethyl-14beta-hydroxy-5ß-androstan-Derivate, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen, die dieselben enthalten
DE4344236A1 (de) * 1993-12-23 1995-06-29 Sigma Tau Ind Farmaceuti Neue 17-Iminomethylalkenyl-5beta,14beta-androstan- und 17-Iminoalkyl-5beta,14beta-androstan-Derivate , die auf das kardiovaskuläre System wirken, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten
DE4420501A1 (de) * 1994-06-13 1995-12-14 Sigma Tau Ind Farmaceuti Neue Hydrazino- und Hydroxyamino-14beta-hydroxyandrostanderivate mit Aktivität für das cardiovaskuläre System, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen, die diese enthalten

Also Published As

Publication number Publication date
EP0714908A2 (en) 1996-06-05
US5705662A (en) 1998-01-06
EP0714908B1 (en) 1998-02-25
DE69501660T2 (de) 1998-07-09
HK1009334A1 (en) 1999-05-28
DE69501660D1 (de) 1998-04-02
EP0714908A3 (da) 1996-06-19
DE4442486A1 (de) 1996-05-30
ES2112597T3 (es) 1998-04-01
JP3899136B2 (ja) 2007-03-28
CA2163935C (en) 2007-03-06
ATE163424T1 (de) 1998-03-15
JPH08225591A (ja) 1996-09-03
CA2163935A1 (en) 1996-05-30

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