HK1009334A1 - New 17(3-imino-2-alkyl-propenyl)-5beta 14beta-androstane derivatives active on the cardiovascular system processes for their preparation and pharmaceutical compositions containing same - Google Patents

New 17(3-imino-2-alkyl-propenyl)-5beta 14beta-androstane derivatives active on the cardiovascular system processes for their preparation and pharmaceutical compositions containing same

Info

Publication number
HK1009334A1
HK1009334A1 HK98109958A HK98109958A HK1009334A1 HK 1009334 A1 HK1009334 A1 HK 1009334A1 HK 98109958 A HK98109958 A HK 98109958A HK 98109958 A HK98109958 A HK 98109958A HK 1009334 A1 HK1009334 A1 HK 1009334A1
Authority
HK
Hong Kong
Prior art keywords
imino
pharmaceutical compositions
14beta
5beta
propenyl
Prior art date
Application number
HK98109958A
Other languages
English (en)
Inventor
Alberto Cerri
Giuseppe Bianchi
Patrizia Ferrari
Piero Melloni
Maria Quadri
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of HK1009334A1 publication Critical patent/HK1009334A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
HK98109958A 1994-11-29 1998-08-15 New 17(3-imino-2-alkyl-propenyl)-5beta 14beta-androstane derivatives active on the cardiovascular system processes for their preparation and pharmaceutical compositions containing same HK1009334A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4442486A DE4442486A1 (de) 1994-11-29 1994-11-29 Neue 17-(3-Imino-2-alkylpropylen)-5ß,14ß-androstan-Derivate, die auf das kardiovaskuläre System wirken, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen

Publications (1)

Publication Number Publication Date
HK1009334A1 true HK1009334A1 (en) 1999-05-28

Family

ID=6534459

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98109958A HK1009334A1 (en) 1994-11-29 1998-08-15 New 17(3-imino-2-alkyl-propenyl)-5beta 14beta-androstane derivatives active on the cardiovascular system processes for their preparation and pharmaceutical compositions containing same

Country Status (9)

Country Link
US (1) US5705662A (xx)
EP (1) EP0714908B1 (xx)
JP (1) JP3899136B2 (xx)
AT (1) ATE163424T1 (xx)
CA (1) CA2163935C (xx)
DE (2) DE4442486A1 (xx)
DK (1) DK0714908T3 (xx)
ES (1) ES2112597T3 (xx)
HK (1) HK1009334A1 (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030083231A1 (en) * 1998-11-24 2003-05-01 Ahlem Clarence N. Blood cell deficiency treatment method
US6764817B1 (en) * 1999-04-20 2004-07-20 Target Discovery, Inc. Methods for conducting metabolic analyses

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4222404C1 (de) * 1992-07-08 1993-12-02 Sigma Tau Ind Farmaceuti Verwendung von Iminoderivaten von Etianaldehyd zur Behandlung von Hypertonie
DE4227605C2 (de) * 1992-08-20 1995-02-16 Sigma Tau Ind Farmaceuti 17-Hydroxyiminomethyl-14beta-hydroxy-5ß-androstan-Derivate, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen, die dieselben enthalten
DE4344236A1 (de) * 1993-12-23 1995-06-29 Sigma Tau Ind Farmaceuti Neue 17-Iminomethylalkenyl-5beta,14beta-androstan- und 17-Iminoalkyl-5beta,14beta-androstan-Derivate , die auf das kardiovaskuläre System wirken, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten
DE4420501A1 (de) * 1994-06-13 1995-12-14 Sigma Tau Ind Farmaceuti Neue Hydrazino- und Hydroxyamino-14beta-hydroxyandrostanderivate mit Aktivität für das cardiovaskuläre System, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen, die diese enthalten

Also Published As

Publication number Publication date
EP0714908A3 (xx) 1996-06-19
CA2163935C (en) 2007-03-06
EP0714908A2 (en) 1996-06-05
DE69501660T2 (de) 1998-07-09
EP0714908B1 (en) 1998-02-25
US5705662A (en) 1998-01-06
DK0714908T3 (da) 1998-09-28
JP3899136B2 (ja) 2007-03-28
JPH08225591A (ja) 1996-09-03
ES2112597T3 (es) 1998-04-01
ATE163424T1 (de) 1998-03-15
DE4442486A1 (de) 1996-05-30
CA2163935A1 (en) 1996-05-30
DE69501660D1 (de) 1998-04-02

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20091103