DK0707566T3 - Hidtil ukendte strukturelle analoger til vitamin D - Google Patents

Hidtil ukendte strukturelle analoger til vitamin D

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Publication number
DK0707566T3
DK0707566T3 DK94924749T DK94924749T DK0707566T3 DK 0707566 T3 DK0707566 T3 DK 0707566T3 DK 94924749 T DK94924749 T DK 94924749T DK 94924749 T DK94924749 T DK 94924749T DK 0707566 T3 DK0707566 T3 DK 0707566T3
Authority
DK
Denmark
Prior art keywords
vitamin
ring
hitherto unknown
structural analogues
analogue
Prior art date
Application number
DK94924749T
Other languages
Danish (da)
English (en)
Inventor
Roger Bouillon
Maurits Vandewalle
Clercq Pierre Jean De
Original Assignee
Theramex
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theramex filed Critical Theramex
Application granted granted Critical
Publication of DK0707566T3 publication Critical patent/DK0707566T3/da

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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/02—Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen
    • C07C47/198—Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen containing ether groups, groups, groups, or groups
    • A—HUMAN NECESSITIES
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    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
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    • A61P17/00—Drugs for dermatological disorders
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    • C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/22—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/22—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
    • C07C35/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
    • C07C35/27—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings the condensed ring system containing six carbon atoms
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    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
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    • C07C47/19—Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen containing hydroxy groups
    • C07C47/192—Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen containing hydroxy groups containing rings
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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/28—Saturated compounds having —CHO groups bound to carbon atoms of rings other than six—membered aromatic rings
    • C07C47/37—Saturated compounds having —CHO groups bound to carbon atoms of rings other than six—membered aromatic rings containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/24—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups
    • C07C49/242—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups containing rings other than six-membered aromatic rings
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    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385—Saturated compounds containing a keto group being part of a ring
    • C07C49/517—Saturated compounds containing a keto group being part of a ring containing ether groups, groups, groups, or groups
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    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
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    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/743—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups having unsaturation outside the rings, e.g. humulones, lupulones
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    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • C07C49/755—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring
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    • C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups

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  • Animal Behavior & Ethology (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK94924749T 1993-07-09 1994-07-07 Hidtil ukendte strukturelle analoger til vitamin D DK0707566T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP93202037 1993-07-09
PCT/EP1994/002294 WO1995001960A1 (fr) 1993-07-09 1994-07-07 Nouveaux analogues structuraux de la vitamine d

Publications (1)

Publication Number Publication Date
DK0707566T3 true DK0707566T3 (da) 2000-09-04

Family

ID=8213977

Family Applications (2)

Application Number Title Priority Date Filing Date
DK99203513T DK0972762T3 (da) 1993-07-09 1994-07-07 Hidtil ukendte strukturelle analoger af vitamin D
DK94924749T DK0707566T3 (da) 1993-07-09 1994-07-07 Hidtil ukendte strukturelle analoger til vitamin D

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK99203513T DK0972762T3 (da) 1993-07-09 1994-07-07 Hidtil ukendte strukturelle analoger af vitamin D

Country Status (16)

Country Link
US (2) US6017907A (fr)
EP (2) EP0972762B1 (fr)
JP (2) JP4235256B2 (fr)
CN (1) CN1103755C (fr)
AT (2) ATE191712T1 (fr)
AU (1) AU699200B2 (fr)
CA (1) CA2166898C (fr)
DE (2) DE69423966T2 (fr)
DK (2) DK0972762T3 (fr)
ES (2) ES2209327T3 (fr)
GR (1) GR3033856T3 (fr)
NO (1) NO314142B1 (fr)
NZ (1) NZ271332A (fr)
PT (2) PT707566E (fr)
RU (1) RU2153491C2 (fr)
WO (1) WO1995001960A1 (fr)

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US5716946A (en) * 1996-02-13 1998-02-10 Wisconsin Alumni Research Foundation Multiple sclerosis treatment
DE19619036A1 (de) 1996-04-30 1997-11-13 Schering Ag Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
EP0983221B1 (fr) * 1997-05-23 2002-04-03 Basilea Pharmaceutica AG Derives cyclohexanediol
AUPO727097A0 (en) * 1997-06-10 1997-07-03 Unisearch Limited Method of treatment of hepatoma and pharmaceutical compositions for use therein
AU735676B2 (en) * 1997-06-10 2001-07-12 Mrc Holdings Pty Limited Method of treatment of liver tumours and pharmaceutical compositions for use therein
WO1999012894A1 (fr) * 1997-09-08 1999-03-18 F. Hoffmann-La Roche Ag Analogues de vitamine d3 de 1,3-dihydroxy-20,20-dialkyle
US5919986A (en) * 1997-10-17 1999-07-06 Hoffmann-La Roche Inc. D-homo vitamin D3 derivatives
EP1061070B1 (fr) * 1998-02-24 2008-07-16 Chugai Seiyaku Kabushiki Kaisha Procédé pour la préparation de ED-71
US6184422B1 (en) 1998-02-26 2001-02-06 Hoffman-La Roche Inc. Cyclohexanediol derivatives
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US5962707A (en) * 1998-08-18 1999-10-05 Wisconsin Alumni Research Foundation 19-nor-vitamin D3 compounds with calcemic activity
US6479474B2 (en) 1999-07-08 2002-11-12 Wisconsin Alumni Research Foundation Dietary calcium as a supplement to vitamin D compound treatment of multiple sclerosis
DE19935771A1 (de) * 1999-07-23 2001-02-01 Schering Ag Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
US6310262B1 (en) * 1999-10-18 2001-10-30 Basilea Pharmaceutica Ag Process for preparing retiferol derivatives
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US6191292B1 (en) * 1999-12-08 2001-02-20 Laboratoire Theramex Precursors of the A-ring of vitamin D and method and intermediates for the preparation thereof
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US7713951B2 (en) * 2004-04-09 2010-05-11 Wisconsin Alumni Research Foundation 2-alkylidene-18,19-dinor-vitamin D compounds
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US6017907A (en) 2000-01-25
ES2209327T3 (es) 2004-06-16
AU699200B2 (en) 1998-11-26
EP0707566A1 (fr) 1996-04-24
DE69423966T2 (de) 2000-11-16
DE69433220D1 (de) 2003-11-06
ATE251133T1 (de) 2003-10-15
DK0972762T3 (da) 2004-02-09
ATE191712T1 (de) 2000-04-15
WO1995001960A1 (fr) 1995-01-19
CA2166898C (fr) 2004-09-07
JPH09500117A (ja) 1997-01-07
JP4235256B2 (ja) 2009-03-11
JP4312183B2 (ja) 2009-08-12
CA2166898A1 (fr) 1995-01-19
ES2147238T3 (es) 2000-09-01
CN1103755C (zh) 2003-03-26
RU2153491C2 (ru) 2000-07-27
EP0707566B1 (fr) 2000-04-12
DE69423966D1 (de) 2000-05-18
US6548715B1 (en) 2003-04-15
DE69433220T2 (de) 2004-08-19
EP0972762A2 (fr) 2000-01-19
NO960099D0 (no) 1996-01-09
GR3033856T3 (en) 2000-10-31
EP0972762B1 (fr) 2003-10-01
NO960099L (no) 1996-03-08
CN1130899A (zh) 1996-09-11
NZ271332A (en) 2001-03-30
NO314142B1 (no) 2003-02-03
JP2006001944A (ja) 2006-01-05
PT972762E (pt) 2004-02-27
AU7492794A (en) 1995-02-06
PT707566E (pt) 2000-09-29

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