DK0706370T4 - Anvendelse af nonioniske overfladeaktive stoffer i stabile topiske retinoidsammensætninger - Google Patents

Anvendelse af nonioniske overfladeaktive stoffer i stabile topiske retinoidsammensætninger

Info

Publication number
DK0706370T4
DK0706370T4 DK94923832T DK94923832T DK0706370T4 DK 0706370 T4 DK0706370 T4 DK 0706370T4 DK 94923832 T DK94923832 T DK 94923832T DK 94923832 T DK94923832 T DK 94923832T DK 0706370 T4 DK0706370 T4 DK 0706370T4
Authority
DK
Denmark
Prior art keywords
pct
nonionic surfactants
retinoid
sec
stable topical
Prior art date
Application number
DK94923832T
Other languages
Danish (da)
English (en)
Other versions
DK0706370T3 (da
Inventor
Harrewijn Antoon Van
Aart Muehlenbruch
Vringer Tom De
Original Assignee
Yamanouchi Europ Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8213946&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0706370(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yamanouchi Europ Bv filed Critical Yamanouchi Europ Bv
Publication of DK0706370T3 publication Critical patent/DK0706370T3/da
Application granted granted Critical
Publication of DK0706370T4 publication Critical patent/DK0706370T4/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/90—Block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Toxicology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK94923832T 1993-07-01 1994-07-01 Anvendelse af nonioniske overfladeaktive stoffer i stabile topiske retinoidsammensætninger DK0706370T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP93201931 1993-07-01
PCT/NL1994/000151 WO1995001160A1 (en) 1993-07-01 1994-07-01 Stable topical retinoid compositions

Publications (2)

Publication Number Publication Date
DK0706370T3 DK0706370T3 (da) 2001-09-17
DK0706370T4 true DK0706370T4 (da) 2005-04-18

Family

ID=8213946

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94923832T DK0706370T4 (da) 1993-07-01 1994-07-01 Anvendelse af nonioniske overfladeaktive stoffer i stabile topiske retinoidsammensætninger

Country Status (23)

Country Link
US (1) US5690923A (cs)
EP (1) EP0706370B2 (cs)
JP (2) JP3947215B2 (cs)
AT (1) ATE202694T1 (cs)
AU (1) AU678039B2 (cs)
BG (1) BG61713B1 (cs)
CA (1) CA2166062C (cs)
CZ (1) CZ285679B6 (cs)
DE (1) DE69427639T3 (cs)
DK (1) DK0706370T4 (cs)
ES (1) ES2160631T5 (cs)
FI (1) FI115607B (cs)
GR (1) GR3036761T3 (cs)
HU (1) HU217869B (cs)
MD (1) MD1587C2 (cs)
NO (1) NO311066B1 (cs)
PT (1) PT706370E (cs)
RO (1) RO115109B1 (cs)
RU (1) RU2134101C1 (cs)
SI (1) SI0706370T2 (cs)
SK (1) SK279919B6 (cs)
UA (1) UA41937C2 (cs)
WO (1) WO1995001160A1 (cs)

Families Citing this family (42)

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CA2166062C (en) * 1993-07-01 2008-09-16 Tom De Vringer The use of non-ionic surfactants in stable topical retinoid compositions
WO1998018492A1 (en) * 1996-10-25 1998-05-07 Yoshitomi Pharmaceutical Industries Ltd. Method of inhibiting drug precipitation
DE19903729A1 (de) * 1999-01-30 2000-08-03 Beiersdorf Ag Verwendung von oberflächenaktiven Citronensäureestern zur Stabilisierung von Retinoiden, synergistische Gemische aus Retinoiden und oberflächenaktiven Substanzen sowie kosmetische und dermatologische Zubereitungen mit einem Gehalt an solchen Gemischen
AU6439400A (en) * 1999-08-20 2001-03-19 Unilever Plc Skin cosmetic compositions for reducing skin irritation from weak carboxylic acids
DE10025756C2 (de) * 2000-05-25 2003-02-20 Cognis Deutschland Gmbh Lösungsvermittler
RU2166309C1 (ru) * 2000-06-26 2001-05-10 Разумова Татьяна Николаевна Лечебно-профилактическая и косметическая композиция
US6387383B1 (en) 2000-08-03 2002-05-14 Dow Pharmaceutical Sciences Topical low-viscosity gel composition
US7060732B2 (en) * 2000-12-12 2006-06-13 Imaginative Research Associates, Inc. Antibiotic/benzoyl peroxide dispenser
US20060189552A1 (en) * 2000-12-12 2006-08-24 Mohan Vishnupad Dispenser for dispensing three or more actives
RU2197235C1 (ru) * 2002-04-05 2003-01-27 Фармацевтическое научно-производственное предприятие "Ретиноиды" (акционерное общество закрытого типа) Раствор для лечения заболеваний кожи, способ его получения и способ лечения заболеваний кожи
US20030215493A1 (en) * 2002-04-30 2003-11-20 Patel Pravin M. Composition and method for dermatological treatment
US20110142922A1 (en) * 2002-04-30 2011-06-16 Ferndale Ip, Inc. Stabilized composition and method for dermatological treatment
US7939489B2 (en) * 2002-12-23 2011-05-10 Avon Products, Inc. Oil absorbent topical compositions and methods for using same
US7141237B2 (en) 2003-01-24 2006-11-28 Connetics Australia Pty Ltd. Pharmaceutical foam
US20060014834A1 (en) * 2004-05-11 2006-01-19 Mohan Vishnupad Retinoid solutions and formulations made therefrom
US7662855B2 (en) * 2004-05-11 2010-02-16 Imaginative Research Associates, Inc. Retinoid solutions and formulations made therefrom
ATE467411T1 (de) 2004-11-09 2010-05-15 Imaginative Res Associates Inc Retinoidlösungen und formulierungen daraus
WO2006055869A2 (en) * 2004-11-19 2006-05-26 Aventis Pharmaceuticals Inc. Antibiotic compounds, compositions and medical uses
WO2006089070A2 (en) * 2005-02-17 2006-08-24 Connetics Corporation Acne gel
AR054805A1 (es) * 2005-06-29 2007-07-18 Stiefel Laboratories Composiciones topicas para el tratamiento de la piel
US9107844B2 (en) * 2006-02-03 2015-08-18 Stiefel Laboratories Inc. Topical skin treating compositions
NZ571818A (en) * 2006-03-08 2011-10-28 Nihon Nohyaku Co Ltd External pharmaceutical composition comprising luliconazole and an alpha-hydroxycarboxylic acid such as lactic acid, glycolic acid or malic acid.
JP5160409B2 (ja) * 2006-03-08 2013-03-13 日本農薬株式会社 外用の医薬組成物
ES2582654T3 (es) 2006-03-31 2016-09-14 Stiefel Research Australia Pty Ltd Gel en suspensión espumable
US20080287373A1 (en) * 2007-05-17 2008-11-20 Popp Karl F Topical skin treating kits
EP2170254A2 (en) * 2007-06-21 2010-04-07 Dow Global Technologies Inc. Stabilizers for hydrophobic components in personal care compositions
KR20100075476A (ko) 2007-09-05 2010-07-02 가부시키가이샤 폴라 파마 항진균 조성물
WO2009031644A1 (ja) * 2007-09-05 2009-03-12 Pola Pharma Inc. 抗真菌医薬組成物
WO2009031642A1 (ja) * 2007-09-05 2009-03-12 Pola Pharma Inc. 医薬組成物
EP2214661A4 (en) * 2007-10-18 2012-10-03 Medicis Pharmaceutical Corp AQUEOUS RETINOID AND DIBENZOYL PEROXIDE GEL
FR2939683B1 (fr) * 2008-12-17 2012-04-20 Oreal Composition cosmetique comprenant un polyester sulfonique ramifie et un tensioactif particulier et utilisations en coiffage
JP5688406B2 (ja) * 2009-04-09 2015-03-25 株式会社ポーラファルマ 抗真菌医薬組成物
KR101409789B1 (ko) 2009-04-09 2014-06-19 니혼노야쿠가부시키가이샤 항진균성 약제학적 조성물
EP2470178B1 (en) 2009-08-25 2018-10-17 Pola Pharma Inc. Antimycotic pharmaceutical composition
US11071878B2 (en) * 2009-12-31 2021-07-27 Sol-Gel Technologies Ltd. Core stabilized microcapsules, method of their preparation and uses thereof
EP2726067B1 (en) 2011-06-29 2020-02-19 Sol-Gel Technologies Ltd. Stabilized topical formulations containing core-shell microcapsules
JP5865624B2 (ja) * 2011-08-01 2016-02-17 昭和電工株式会社 皮膚外用剤およびその製造方法
JP5865623B2 (ja) * 2011-08-01 2016-02-17 昭和電工株式会社 皮膚外用剤およびその製造方法
FR2991175B1 (fr) * 2012-06-01 2014-12-19 Galderma Res & Dev Compositions pharmaceutiques topiques de type emulsion h/e contenant un retinoide
MD4479C1 (ro) * 2015-02-12 2017-12-31 Валериу НИКУШОР Compoziţie de erbicide şi procedeu de combatere a buruienilor şi ierburilor în culturile de sfeclă de zahăr cu utilizarea acesteia
JP2020527140A (ja) 2017-07-12 2020-09-03 ソル − ゲル テクノロジーズ リミテッド カプセル化トレチノインを含む組成物
AU2021274996A1 (en) 2020-05-22 2023-02-02 Sol-Gel Technologies Ltd. Stabilized microcapsules, method of their preparation and uses thereof

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US4532133A (en) * 1983-05-24 1985-07-30 Basf Wyandotte Corporation Low temperature stable, emulsifiable vitamin A concentrates
FR2591105B1 (fr) * 1985-12-11 1989-03-24 Moet Hennessy Rech Composition pharmaceutique, notamment dermatologique, ou cosmetique, a base de phases lamellaires lipidiques hydratees ou de liposomes contenant un retinoide ou un analogue structural dudit retinoide tel qu'un carotenoide.
GB8821129D0 (en) † 1988-09-09 1988-10-12 Unilever Plc Cosmetic composition
MY105521A (en) * 1989-04-17 1994-10-31 Healthpoint Ltd Moisturizing vehicle for topical application of vitamin a acid.
US5721275A (en) * 1989-06-07 1998-02-24 Bazzano; Gail S. Slow release vehicles for minimizing skin irritancy of topical compositions
JP2827295B2 (ja) * 1989-07-04 1998-11-25 大正製薬株式会社 ビタミンａ類含有点眼剤
FI903483A7 (fi) † 1989-07-13 1991-01-14 Bristol Myers Squibb Co Tretinoiinia sisältäviä stabiileja emulsiovoideformuloita
SU1713555A1 (ru) * 1989-10-04 1992-02-23 Научно-производственное объединение "Аэрозоль" Лосьон дл ухода за жирной кожей лица
US5043356A (en) * 1990-01-19 1991-08-27 Fulton Jr James E Composition and method for rejuvenating skin using vitamin A propionate
JP3031990B2 (ja) * 1990-10-19 2000-04-10 同仁医薬化工株式会社 消炎鎮痛クリーム剤組成物
CA2166062C (en) * 1993-07-01 2008-09-16 Tom De Vringer The use of non-ionic surfactants in stable topical retinoid compositions

Also Published As

Publication number Publication date
DE69427639D1 (de) 2001-08-09
MD1587B2 (en) 2001-01-31
CA2166062C (en) 2008-09-16
ES2160631T3 (es) 2001-11-16
NO311066B1 (no) 2001-10-08
RO115109B1 (ro) 1999-11-30
CZ285679B6 (cs) 1999-10-13
JP3947215B2 (ja) 2007-07-18
EP0706370B2 (en) 2005-01-26
SK279919B6 (sk) 1999-05-07
NO955193D0 (no) 1995-12-20
SI0706370T2 (en) 2005-06-30
CZ348395A3 (en) 1996-04-17
FI115607B (fi) 2005-06-15
JP2006328089A (ja) 2006-12-07
GR3036761T3 (en) 2001-12-31
DK0706370T3 (da) 2001-09-17
PT706370E (pt) 2001-11-30
BG61713B1 (bg) 1998-04-30
AU7391394A (en) 1995-01-24
WO1995001160A1 (en) 1995-01-12
RU2134101C1 (ru) 1999-08-10
US5690923A (en) 1997-11-25
HU217869B (hu) 2000-04-28
ES2160631T5 (es) 2005-07-16
MD950443A (en) 1997-09-30
UA41937C2 (uk) 2001-10-15
BG100267A (bg) 1996-07-31
HU9503721D0 (en) 1996-02-28
EP0706370A1 (en) 1996-04-17
NO955193L (no) 1996-02-08
JPH08512049A (ja) 1996-12-17
ATE202694T1 (de) 2001-07-15
CA2166062A1 (en) 1995-01-12
FI956204L (fi) 1995-12-22
HUT74072A (en) 1996-10-28
DE69427639T2 (de) 2001-10-18
FI956204A0 (fi) 1995-12-22
EP0706370B1 (en) 2001-07-04
DE69427639T3 (de) 2005-08-04
MD1587C2 (ro) 2001-06-30
AU678039B2 (en) 1997-05-15
SK159795A3 (en) 1997-03-05
SI0706370T1 (en) 2001-12-31

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