DK0682024T3 - Cyclohexan-derivater, fremgangsmåder til fremstilling og deres anvendelse som glucose-6-phosphatase inhibitorer - Google Patents

Cyclohexan-derivater, fremgangsmåder til fremstilling og deres anvendelse som glucose-6-phosphatase inhibitorer

Info

Publication number
DK0682024T3
DK0682024T3 DK95106760T DK95106760T DK0682024T3 DK 0682024 T3 DK0682024 T3 DK 0682024T3 DK 95106760 T DK95106760 T DK 95106760T DK 95106760 T DK95106760 T DK 95106760T DK 0682024 T3 DK0682024 T3 DK 0682024T3
Authority
DK
Denmark
Prior art keywords
glucose
preparation
methods
phosphatase inhibitors
cyclohexane derivatives
Prior art date
Application number
DK95106760T
Other languages
Danish (da)
English (en)
Inventor
Horst Dr Hemmerle
Gerrit Dr Schubert
Hans-Joerg Dr Burger
Andreas Dr Herling
Suad Prof Dr Efendic
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Application granted granted Critical
Publication of DK0682024T3 publication Critical patent/DK0682024T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK95106760T 1994-05-10 1995-05-04 Cyclohexan-derivater, fremgangsmåder til fremstilling og deres anvendelse som glucose-6-phosphatase inhibitorer DK0682024T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4416433A DE4416433A1 (de) 1994-05-10 1994-05-10 Cyclohexan-Derivate, Verfahren zu ihrer Herstellung und die Verwendung der Verbindungen zur Behandlung von Krankheiten

Publications (1)

Publication Number Publication Date
DK0682024T3 true DK0682024T3 (da) 2000-05-22

Family

ID=6517746

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95106760T DK0682024T3 (da) 1994-05-10 1995-05-04 Cyclohexan-derivater, fremgangsmåder til fremstilling og deres anvendelse som glucose-6-phosphatase inhibitorer

Country Status (23)

Country Link
US (1) US5739147A (no)
EP (1) EP0682024B1 (no)
JP (1) JP3790564B2 (no)
KR (1) KR100355690B1 (no)
CN (1) CN1043643C (no)
AT (1) ATE187454T1 (no)
AU (1) AU683148B2 (no)
CA (1) CA2149007C (no)
CZ (1) CZ288443B6 (no)
DE (2) DE4416433A1 (no)
DK (1) DK0682024T3 (no)
ES (1) ES2141276T3 (no)
FI (1) FI110097B (no)
GR (1) GR3032519T3 (no)
HK (1) HK1011989A1 (no)
HU (1) HU220865B1 (no)
NO (1) NO304314B1 (no)
NZ (1) NZ272082A (no)
PL (1) PL180074B1 (no)
RU (1) RU2140416C1 (no)
TW (1) TW421648B (no)
UA (1) UA41340C2 (no)
ZA (1) ZA953726B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW526202B (en) 1998-11-27 2003-04-01 Shionogi & Amp Co Broad spectrum cephem having benzo[4,5-b]pyridium methyl group of antibiotic activity
DE122008000018I1 (de) 2000-01-21 2008-08-14 Novartis Pharma Ag Zusammensetzungen bestehend aus Dipeptidylpeptidase-IV Inhibitoren und Antidiabetica
EP1385549A2 (en) * 2001-03-12 2004-02-04 Novartis AG Combination of nateglinide or repaglinide with at least one further antidiabetic compound
CA2622608C (en) 2005-09-14 2014-08-19 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors for treating diabetes
WO2011041293A1 (en) 2009-09-30 2011-04-07 Takeda Pharmaceutical Company Limited Pyrazolo [1, 5-a] pyrimidine derivatives as apoptosis signal-regulating kinase 1 inhibitors
CN102834393B (zh) 2010-02-03 2015-07-22 武田药品工业株式会社 细胞凋亡信号调节激酶1抑制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60243016A (ja) * 1984-05-17 1985-12-03 Tsumura Juntendo Inc 抗インフルエンザウイルス剤
TW255880B (no) * 1992-09-09 1995-09-01 Hoechst Ag
TW399041B (en) * 1992-09-09 2000-07-21 Hoechst Ag Substituted cyclohexane derivatives, the preparation and the use for treating diseases
DE4408082A1 (de) * 1994-03-10 1995-09-14 Hoechst Ag Substituierte Propan-Derivate, Verfahren zu ihrer Herstellung und die Anwendung der Verbindungen zur Behandlung von Krankheiten
DE4413402A1 (de) * 1994-04-18 1995-10-19 Hoechst Ag Verfahren zur Herstellung von Zwischenprodukten für die Synthese von Glucose-6-Phosphatase-Inhibitoren sowie neue Zwischenprodukte

Also Published As

Publication number Publication date
PL308521A1 (en) 1995-11-13
PL180074B1 (pl) 2000-12-29
KR950032191A (ko) 1995-12-20
CZ119595A3 (en) 1995-12-13
FI110097B (fi) 2002-11-29
HK1011989A1 (en) 1999-07-23
NO304314B1 (no) 1998-11-30
HU220865B1 (en) 2002-06-29
HUT71797A (en) 1996-02-28
CA2149007C (en) 2005-07-26
NZ272082A (en) 1996-09-25
RU95107147A (ru) 1997-03-20
NO951820L (no) 1995-11-13
EP0682024B1 (de) 1999-12-08
DE4416433A1 (de) 1995-11-16
RU2140416C1 (ru) 1999-10-27
ATE187454T1 (de) 1999-12-15
UA41340C2 (uk) 2001-09-17
ZA953726B (en) 1996-01-11
AU1792395A (en) 1995-11-16
CZ288443B6 (en) 2001-06-13
KR100355690B1 (ko) 2002-12-26
DE59507361D1 (de) 2000-01-13
NO951820D0 (no) 1995-05-09
CN1043643C (zh) 1999-06-16
JPH07330767A (ja) 1995-12-19
EP0682024A1 (de) 1995-11-15
FI952203A (fi) 1995-11-11
CA2149007A1 (en) 1995-11-11
CN1118782A (zh) 1996-03-20
FI952203A0 (fi) 1995-05-08
TW421648B (en) 2001-02-11
US5739147A (en) 1998-04-14
JP3790564B2 (ja) 2006-06-28
AU683148B2 (en) 1997-10-30
ES2141276T3 (es) 2000-03-16
GR3032519T3 (en) 2000-05-31

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