DK0680470T3 - - Google Patents

Info

Publication number
DK0680470T3
DK0680470T3 DK94906446.3T DK94906446T DK0680470T3 DK 0680470 T3 DK0680470 T3 DK 0680470T3 DK 94906446 T DK94906446 T DK 94906446T DK 0680470 T3 DK0680470 T3 DK 0680470T3
Authority
DK
Denmark
Prior art keywords
pct
sec
date
tumors
pub
Prior art date
Application number
DK94906446.3T
Other languages
Danish (da)
English (en)
Inventor
Jules Freedman
Sai P Sunkara
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Application granted granted Critical
Publication of DK0680470T3 publication Critical patent/DK0680470T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/16Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with acylated ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK94906446.3T 1993-01-21 1993-12-17 DK0680470T3 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US656993A 1993-01-21 1993-01-21

Publications (1)

Publication Number Publication Date
DK0680470T3 true DK0680470T3 (no) 1997-04-28

Family

ID=21721516

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94906446.3T DK0680470T3 (no) 1993-01-21 1993-12-17

Country Status (20)

Country Link
US (1) US5648365A (no)
EP (1) EP0680470B1 (no)
JP (1) JP3398748B2 (no)
KR (1) KR100377280B1 (no)
AT (1) ATE150748T1 (no)
AU (1) AU679723B2 (no)
CA (1) CA2152794C (no)
DE (1) DE69309310T2 (no)
DK (1) DK0680470T3 (no)
ES (1) ES2102830T3 (no)
FI (1) FI112474B (no)
GR (1) GR3023188T3 (no)
HU (1) HUT72078A (no)
IL (1) IL108369A (no)
MX (1) MX9400563A (no)
NO (1) NO305166B1 (no)
NZ (1) NZ261414A (no)
TW (1) TW243445B (no)
WO (1) WO1994017040A1 (no)
ZA (1) ZA94317B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU662602B2 (en) * 1992-02-06 1995-09-07 Merrell Dow Pharmaceuticals Inc. Reversal of multi-drug resistance by triphenyl-azacycloalkane derivatives
AU6366000A (en) * 1999-07-23 2001-02-13 Colorado State University Research Foundation Multidrug resistance pump inhibitors and uses thereof
US6693099B2 (en) 2000-10-17 2004-02-17 The Procter & Gamble Company Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
AU2002363523A1 (en) * 2001-11-07 2003-05-19 Pharmacia Corporation Methods of promoting uptake and nuclear accumulation of polyamides in eukaryotic cells
US8153184B2 (en) * 2001-11-26 2012-04-10 Samsung Mobile Display Co., Ltd. Organic EL display device and method of manufacturing the same
KR100656490B1 (ko) 2001-11-26 2006-12-12 삼성에스디아이 주식회사 풀칼라 유기전계 발광표시소자 및 그의 제조방법
ES2704880T3 (es) 2013-02-08 2019-03-20 Gen Mills Inc Productos alimentarios reducidos en sodio
CN110372571B (zh) * 2018-04-12 2022-11-15 中国科学院大连化学物理研究所 一种2-(2,2-二芳基乙基)-环胺衍生物或盐及合成和应用与组合物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1049377B (de) * 1952-04-03 1959-01-29 Abbott Laboratories, North Chicago, 111. (V. St. A.) Verfahren zur Herstellung von substituierten Vinylpiperidinen
US2898339A (en) * 1957-07-29 1959-08-04 Wm S Merrell Co N-substituted benzhydrol, benzhydryl, and benzhydrylidene piperidine
US3956296A (en) * 1974-12-11 1976-05-11 A. H. Robins Company, Incorporated 1-Substituted-4-benzylpiperidines
US4035372A (en) * 1976-08-13 1977-07-12 G. D. Searle & Co. 4-{[4-(Diphenylmethyl)-1-piperidinyl]methyl}benzenamines
EP0235463A3 (en) * 1985-12-20 1990-01-17 A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents
US4851423A (en) * 1986-12-10 1989-07-25 Schering Corporation Pharmaceutically active compounds
US4990511A (en) * 1988-08-03 1991-02-05 Takeda Chemical Industries, Ltd. Amide compounds, their production and use
ATE94061T1 (de) * 1989-06-19 1993-09-15 Wellcome Found Arylsubstituierte aminderivate verwendbar in der krebstherapie.
GB9000305D0 (en) * 1990-01-06 1990-03-07 Pfizer Ltd Anticholinergic agents
EP0467435A3 (en) * 1990-07-19 1992-04-01 Akzo N.V. Benzhydryl derivatives having calmodulin inhibitor properties
EP0471612B1 (fr) * 1990-08-14 1998-01-28 Roussel Uclaf Nouveaux 19-Nor stéroides ayant en position 11béta une chaíne carbonée comportant une fonction amide, leur préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant
AU662602B2 (en) * 1992-02-06 1995-09-07 Merrell Dow Pharmaceuticals Inc. Reversal of multi-drug resistance by triphenyl-azacycloalkane derivatives

Also Published As

Publication number Publication date
ZA94317B (en) 1994-08-18
JP3398748B2 (ja) 2003-04-21
FI953506A0 (fi) 1995-07-20
ES2102830T3 (es) 1997-08-01
KR100377280B1 (ko) 2003-07-18
AU679723B2 (en) 1997-07-10
HU9502195D0 (en) 1995-09-28
HUT72078A (en) 1996-03-28
IL108369A (en) 1999-08-17
EP0680470A1 (en) 1995-11-08
NZ261414A (en) 1997-06-24
IL108369A0 (en) 1994-04-12
GR3023188T3 (en) 1997-07-30
FI112474B (fi) 2003-12-15
NO952885L (no) 1995-09-20
WO1994017040A1 (en) 1994-08-04
ATE150748T1 (de) 1997-04-15
CA2152794A1 (en) 1994-08-04
US5648365A (en) 1997-07-15
JPH08505870A (ja) 1996-06-25
NO305166B1 (no) 1999-04-12
KR960700230A (ko) 1996-01-19
EP0680470B1 (en) 1997-03-26
NO952885D0 (no) 1995-07-20
DE69309310D1 (de) 1997-04-30
AU6014894A (en) 1994-08-15
CA2152794C (en) 1999-04-06
MX9400563A (es) 1994-07-29
FI953506A (fi) 1995-07-20
DE69309310T2 (de) 1997-11-06
TW243445B (no) 1995-03-21

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