DK0662076T3 - 2-aminoalkyl-5-aminoalkylamino-substituerede isoquinoindazol-6(2H)-oner med antitumorvikning - Google Patents

2-aminoalkyl-5-aminoalkylamino-substituerede isoquinoindazol-6(2H)-oner med antitumorvikning

Info

Publication number
DK0662076T3
DK0662076T3 DK93921290T DK93921290T DK0662076T3 DK 0662076 T3 DK0662076 T3 DK 0662076T3 DK 93921290 T DK93921290 T DK 93921290T DK 93921290 T DK93921290 T DK 93921290T DK 0662076 T3 DK0662076 T3 DK 0662076T3
Authority
DK
Denmark
Prior art keywords
alkyl
group
phenylalkyl
hydrogen
substituted
Prior art date
Application number
DK93921290T
Other languages
Danish (da)
English (en)
Inventor
A Paul Krapcho
Ernesto Via Baracca Menta
Ambrogio Via I Maggio Oliva
Silvano Spinelli
Original Assignee
Univ Vermont
Novuspharma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/103,641 external-priority patent/US5519029A/en
Application filed by Univ Vermont, Novuspharma Spa filed Critical Univ Vermont
Application granted granted Critical
Publication of DK0662076T3 publication Critical patent/DK0662076T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK93921290T 1992-09-08 1993-09-08 2-aminoalkyl-5-aminoalkylamino-substituerede isoquinoindazol-6(2H)-oner med antitumorvikning DK0662076T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94160792A 1992-09-08 1992-09-08
US08/103,641 US5519029A (en) 1992-09-08 1993-08-11 2-aminoalkyl-5-aminoalkylamino substituted-isoquinoindazole-6(2H)-ones
PCT/US1993/008241 WO1994006795A1 (en) 1992-09-08 1993-09-08 2-aminoalkyl-5-aminoalkylamino substituted isoquinoindazole-6-(2h)-ones with antitumour activity

Publications (1)

Publication Number Publication Date
DK0662076T3 true DK0662076T3 (da) 2001-05-07

Family

ID=26800681

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93921290T DK0662076T3 (da) 1992-09-08 1993-09-08 2-aminoalkyl-5-aminoalkylamino-substituerede isoquinoindazol-6(2H)-oner med antitumorvikning

Country Status (17)

Country Link
EP (1) EP0662076B1 (fi)
JP (1) JP3497168B2 (fi)
CN (1) CN1051549C (fi)
AT (1) ATE200491T1 (fi)
AU (1) AU680431B2 (fi)
CZ (1) CZ288366B6 (fi)
DE (1) DE69330131T2 (fi)
DK (1) DK0662076T3 (fi)
ES (1) ES2155452T3 (fi)
FI (1) FI109538B (fi)
GR (1) GR3036175T3 (fi)
HU (1) HU220616B1 (fi)
NO (1) NO302618B1 (fi)
PT (1) PT662076E (fi)
RU (1) RU2130937C1 (fi)
SG (1) SG52494A1 (fi)
WO (1) WO1994006795A1 (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5596097A (en) * 1994-03-08 1997-01-21 The University Of Vermont Hetero-annulated indazoles
EP0837861A1 (en) * 1995-07-06 1998-04-29 The University Of Vermont New pyrido-thiopyranoindazoles with antitumor activity
IT1277576B1 (it) * 1995-09-13 1997-11-11 Boehringer Mannheim Italia 2-2-(2-idrossietil) ammino etil -5- 2-metilammino etil ammino indazolo 4,3-gh isochinolin-6 (2h)-one come agente antitumorale
IT1286509B1 (it) * 1996-11-29 1998-07-15 Boehringer Mannheim Italia Derivati 2, 3, 4, 7-tetraidropiridoindazolo-(1,4)benzodiazepinici aventi attivita' antitumorale
US6747039B2 (en) 2002-03-12 2004-06-08 Albany Molecular Research, Inc. Aza-benzothiopyranoindazoles with antitumor activity
CN103787970A (zh) * 2014-01-14 2014-05-14 北京万全德众医药生物技术有限公司 一锅煮法制备6，9-二氟苯并异喹啉-5，10-二酮的工艺

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE56782B1 (en) * 1982-07-23 1991-12-18 Warner Lambert Co Substituted anthra(1,9-cd)pyrazol-6(2h)-ones

Also Published As

Publication number Publication date
HU9500676D0 (en) 1995-04-28
NO302618B1 (no) 1998-03-30
ATE200491T1 (de) 2001-04-15
RU2130937C1 (ru) 1999-05-27
CN1051549C (zh) 2000-04-19
FI951023A0 (fi) 1995-03-06
CZ59895A3 (en) 1995-11-15
JP3497168B2 (ja) 2004-02-16
AU4844193A (en) 1994-04-12
EP0662076A1 (en) 1995-07-12
FI951023A (fi) 1995-03-31
CZ288366B6 (en) 2001-06-13
SG52494A1 (en) 1998-09-28
WO1994006795A1 (en) 1994-03-31
RU95110932A (ru) 1996-12-27
HU220616B1 (hu) 2002-03-28
JPH08503933A (ja) 1996-04-30
ES2155452T3 (es) 2001-05-16
DE69330131D1 (de) 2001-05-17
AU680431B2 (en) 1997-07-31
HUT70145A (en) 1995-09-28
DE69330131T2 (de) 2001-08-30
EP0662076B1 (en) 2001-04-11
CN1101046A (zh) 1995-04-05
GR3036175T3 (en) 2001-10-31
NO950877L (no) 1995-05-08
PT662076E (pt) 2001-09-28
NO950877D0 (no) 1995-03-07
FI109538B (fi) 2002-08-30

Similar Documents

Publication Publication Date Title
WO1998003505A3 (en) Heterocyclic compounds, their production and use
FI943561A0 (fi) Uudet ainekoostumukset
NO20015446D0 (no) Kinolin-derivater som inhibitorer for MEK-enzymer
SE8307133D0 (sv) Carboxamido-derivatives of 5h-1,3,4-thiadiazolo(3,2-a)pyrimidines and process for their preparation
MX9201020A (es) 6,9-bis(amino-substituidas)benzo[g]isoquinolin-5,10-dionas.
DK657988D0 (da) Substituerede alkylaminderivater, deres fremstilling og anvendelse
DK0662076T3 (da) 2-aminoalkyl-5-aminoalkylamino-substituerede isoquinoindazol-6(2H)-oner med antitumorvikning
ES402755A1 (es) Procedimiento para la preparacion de 5-nitro-pirimidinas.
DE69416683T2 (de) Benzolactam-derivate
NO920619L (no) Oxazinobenzazolforbindelser
DE69120348T4 (de) Cyclopropachromenderivate
MY104630A (en) 4(1h) ouinoline derivatives
YU47071B (sh) Spiro jedinjenje