DK0645389T3 - Fremgangsmåde til fremstilling af imidazopyridinderivater - Google Patents
Fremgangsmåde til fremstilling af imidazopyridinderivaterInfo
- Publication number
- DK0645389T3 DK0645389T3 DK94114551.8T DK94114551T DK0645389T3 DK 0645389 T3 DK0645389 T3 DK 0645389T3 DK 94114551 T DK94114551 T DK 94114551T DK 0645389 T3 DK0645389 T3 DK 0645389T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- image
- imidazopyridine derivatives
- imidazopyridines
- general formula
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 125000004857 imidazopyridinyl group Chemical class N1C(=NC2=C1C=CC=N2)* 0.000 title 1
- 150000005232 imidazopyridines Chemical class 0.000 abstract 2
- 229940123413 Angiotensin II antagonist Drugs 0.000 abstract 1
- DFNYGALUNNFWKJ-UHFFFAOYSA-N aminoacetonitrile Chemical compound NCC#N DFNYGALUNNFWKJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002333 angiotensin II receptor antagonist Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH281693 | 1993-09-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0645389T3 true DK0645389T3 (da) | 1997-03-10 |
Family
ID=4242236
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94114551.8T DK0645389T3 (da) | 1993-09-17 | 1994-09-15 | Fremgangsmåde til fremstilling af imidazopyridinderivater |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5446160A (cs) |
| EP (1) | EP0645389B1 (cs) |
| JP (1) | JP3713724B2 (cs) |
| KR (1) | KR950008512A (cs) |
| AT (1) | ATE148702T1 (cs) |
| AU (1) | AU680025B2 (cs) |
| BR (1) | BR9403594A (cs) |
| CA (1) | CA2131680C (cs) |
| CZ (1) | CZ285489B6 (cs) |
| DE (1) | DE59401760D1 (cs) |
| DK (1) | DK0645389T3 (cs) |
| ES (1) | ES2098089T3 (cs) |
| GR (1) | GR3022500T3 (cs) |
| HU (1) | HU218488B (cs) |
| IL (1) | IL110994A (cs) |
| PL (1) | PL305067A1 (cs) |
| RU (1) | RU94033473A (cs) |
| SI (1) | SI0645389T1 (cs) |
| SK (1) | SK111494A3 (cs) |
| TR (1) | TR27788A (cs) |
| TW (1) | TW410225B (cs) |
| ZA (1) | ZA947189B (cs) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9312853D0 (en) | 1993-06-22 | 1993-08-04 | Euro Celtique Sa | Chemical compounds |
| US5922751A (en) | 1994-06-24 | 1999-07-13 | Euro-Celtique, S.A. | Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same |
| US5591776A (en) | 1994-06-24 | 1997-01-07 | Euro-Celtique, S.A. | Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV |
| US6166041A (en) | 1995-10-11 | 2000-12-26 | Euro-Celtique, S.A. | 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma |
| US6075016A (en) | 1996-04-10 | 2000-06-13 | Euro-Celtique S.A. | 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity |
| EE04280B1 (et) | 1997-07-03 | 2004-04-15 | Dupont Pharmaceuticals Company | Imidasopürimidiinid ja imidasopüridiinid neuroloogiliste häirete käitlemiseks |
| US6365589B1 (en) | 1998-07-02 | 2002-04-02 | Bristol-Myers Squibb Pharma Company | Imidazo-pyridines, -pyridazines, and -triazines as corticotropin releasing factor antagonists |
| US6124463A (en) * | 1998-07-02 | 2000-09-26 | Dupont Pharmaceuticals | Benzimidazoles as corticotropin release factor antagonists |
| WO2001044248A1 (en) * | 1999-12-17 | 2001-06-21 | Bristol-Myers Squibb Pharma Company | Imidazopyrimidinyl and imidazopyridinyl derivatives |
| CA2535120A1 (en) | 2003-08-12 | 2005-03-03 | 3M Innovative Properties Company | Hydroxylamine substituted imidazo-containing compounds |
| AU2004268625B2 (en) | 2003-08-27 | 2011-03-31 | 3M Innovative Properties Company | Aryloxy and arylalkyleneoxy substituted imidazoquinolines |
| AU2004270201A1 (en) | 2003-09-05 | 2005-03-17 | 3M Innovative Properties Company | Treatment for CD5+ B cell lymphoma |
| US7544697B2 (en) | 2003-10-03 | 2009-06-09 | Coley Pharmaceutical Group, Inc. | Pyrazolopyridines and analogs thereof |
| CN1897948A (zh) | 2003-10-03 | 2007-01-17 | 3M创新有限公司 | 烷氧基取代的咪唑并喹啉 |
| EP1685129A4 (en) | 2003-11-14 | 2008-10-22 | 3M Innovative Properties Co | OXIMSUBSTITUTED IMIDAZORING CONNECTIONS |
| AU2004291122A1 (en) | 2003-11-14 | 2005-06-02 | 3M Innovative Properties Company | Hydroxylamine substituted imidazo ring compounds |
| NZ547467A (en) | 2003-11-25 | 2010-06-25 | 3M Innovative Properties Co | Substituted imidazo ring system and methods |
| JP2007517035A (ja) | 2003-12-29 | 2007-06-28 | スリーエム イノベイティブ プロパティズ カンパニー | アリールアルケニルおよびアリールアルキニル置換されたイミダゾキノリン |
| WO2005066169A2 (en) | 2003-12-30 | 2005-07-21 | 3M Innovative Properties Company | Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamides |
| TW200612932A (en) | 2004-03-24 | 2006-05-01 | 3M Innovative Properties Co | Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines |
| US8017779B2 (en) | 2004-06-15 | 2011-09-13 | 3M Innovative Properties Company | Nitrogen containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines |
| WO2006065280A2 (en) | 2004-06-18 | 2006-06-22 | 3M Innovative Properties Company | Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and methods |
| US8026366B2 (en) | 2004-06-18 | 2011-09-27 | 3M Innovative Properties Company | Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines |
| US7897609B2 (en) | 2004-06-18 | 2011-03-01 | 3M Innovative Properties Company | Aryl substituted imidazonaphthyridines |
| WO2006074003A2 (en) | 2004-12-30 | 2006-07-13 | 3M Innovative Properties Company | CHIRAL FUSED [1,2]IMIDAZO[4,5-c] RING COMPOUNDS |
| JP5313502B2 (ja) | 2004-12-30 | 2013-10-09 | スリーエム イノベイティブ プロパティズ カンパニー | 置換キラル縮合［１，２］イミダゾ［４，５−ｃ］環状化合物 |
| AU2006210392A1 (en) | 2005-02-04 | 2006-08-10 | Coley Pharmaceutical Group, Inc. | Aqueous gel formulations containing immune response modifiers |
| US7968563B2 (en) | 2005-02-11 | 2011-06-28 | 3M Innovative Properties Company | Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods |
| JP2008535831A (ja) * | 2005-04-01 | 2008-09-04 | コーリー ファーマシューティカル グループ，インコーポレーテッド | 環閉鎖および関連する方法および中間体 |
| CA2602683A1 (en) | 2005-04-01 | 2006-10-12 | Coley Pharmaceutical Group, Inc. | Pyrazolopyridine-1,4-diamines and analogs thereof |
| US7943636B2 (en) | 2005-04-01 | 2011-05-17 | 3M Innovative Properties Company | 1-substituted pyrazolo (3,4-C) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases |
| BRPI0616338A2 (pt) * | 2005-09-23 | 2011-06-14 | Coley Pharm Group Inc | mÉtodo para 1h-imidazo[4,5-c] piridinas e anÁlogos da mesma |
| WO2008008432A2 (en) | 2006-07-12 | 2008-01-17 | Coley Pharmaceutical Group, Inc. | Substituted chiral fused( 1,2) imidazo (4,5-c) ring compounds and methods |
| US20080139608A1 (en) * | 2006-12-06 | 2008-06-12 | Universiteit Leiden | 2,6,8, Trisubstituted 1-deazapurines and their different uses |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3324115A1 (de) * | 1983-07-05 | 1985-01-17 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel |
| FR2643903A1 (fr) * | 1989-03-03 | 1990-09-07 | Union Pharma Scient Appl | Nouveaux derives de benzimidazole, leurs procedes de preparation, intermediaires de synthese, compositions pharmaceutiques les contenant, utiles notamment pour le traitement des maladies cardiovasculaires, et des ulceres duodenaux |
| US5223499A (en) * | 1989-05-30 | 1993-06-29 | Merck & Co., Inc. | 6-amino substituted imidazo[4,5-bipyridines as angiotensin II antagonists |
| US5240938A (en) * | 1991-02-13 | 1993-08-31 | Merck & Co., Inc. | Angiotensin II antagonists incorporating a substituted pyridoimidazolyl ring |
| US5066654A (en) * | 1990-10-22 | 1991-11-19 | A. H. Robins Company, Incorporated | 2-aryl-3-heterocyclicmethyl-3H-imidazo[4,5-b]pyridines as anxiolytics and anticonvulsants |
| US5128327A (en) * | 1991-03-25 | 1992-07-07 | Merck & Co., Inc. | Angiotensin II antagonists incorporating a nitrogen containing six membered ring heterocycle |
-
1994
- 1994-09-08 CA CA002131680A patent/CA2131680C/en not_active Expired - Fee Related
- 1994-09-13 JP JP21837194A patent/JP3713724B2/ja not_active Expired - Fee Related
- 1994-09-15 DE DE59401760T patent/DE59401760D1/de not_active Expired - Fee Related
- 1994-09-15 KR KR1019940023449A patent/KR950008512A/ko not_active Withdrawn
- 1994-09-15 TR TR00943/94A patent/TR27788A/xx unknown
- 1994-09-15 EP EP94114551A patent/EP0645389B1/de not_active Expired - Lifetime
- 1994-09-15 ES ES94114551T patent/ES2098089T3/es not_active Expired - Lifetime
- 1994-09-15 SI SI9430048T patent/SI0645389T1/xx not_active IP Right Cessation
- 1994-09-15 DK DK94114551.8T patent/DK0645389T3/da active
- 1994-09-15 AT AT94114551T patent/ATE148702T1/de not_active IP Right Cessation
- 1994-09-16 BR BR9403594A patent/BR9403594A/pt not_active Application Discontinuation
- 1994-09-16 RU RU94033473/04A patent/RU94033473A/ru unknown
- 1994-09-16 HU HU9402662A patent/HU218488B/hu not_active IP Right Cessation
- 1994-09-16 CZ CZ942266A patent/CZ285489B6/cs not_active IP Right Cessation
- 1994-09-16 SK SK1114-94A patent/SK111494A3/sk unknown
- 1994-09-16 PL PL94305067A patent/PL305067A1/xx unknown
- 1994-09-16 AU AU73058/94A patent/AU680025B2/en not_active Ceased
- 1994-09-16 ZA ZA947189A patent/ZA947189B/xx unknown
- 1994-09-18 IL IL110994A patent/IL110994A/en not_active IP Right Cessation
- 1994-09-19 US US08/308,448 patent/US5446160A/en not_active Expired - Lifetime
- 1994-10-08 TW TW083109361A patent/TW410225B/zh not_active IP Right Cessation
-
1997
- 1997-02-06 GR GR970400075T patent/GR3022500T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU9402662D0 (en) | 1994-11-28 |
| RU94033473A (ru) | 1996-08-10 |
| JPH07179465A (ja) | 1995-07-18 |
| CZ285489B6 (cs) | 1999-08-11 |
| SK111494A3 (en) | 1995-06-07 |
| PL305067A1 (en) | 1995-03-20 |
| GR3022500T3 (en) | 1997-05-31 |
| US5446160A (en) | 1995-08-29 |
| HU218488B (hu) | 2000-09-28 |
| SI0645389T1 (en) | 1997-10-31 |
| IL110994A (en) | 1998-02-08 |
| IL110994A0 (en) | 1994-11-28 |
| EP0645389B1 (de) | 1997-02-05 |
| JP3713724B2 (ja) | 2005-11-09 |
| BR9403594A (pt) | 1995-05-16 |
| TR27788A (tr) | 1995-08-29 |
| ZA947189B (en) | 1995-05-12 |
| ATE148702T1 (de) | 1997-02-15 |
| CZ226694A3 (en) | 1995-04-12 |
| DE59401760D1 (de) | 1997-03-20 |
| HUT68250A (en) | 1995-06-28 |
| CA2131680C (en) | 2006-11-07 |
| EP0645389A1 (de) | 1995-03-29 |
| AU680025B2 (en) | 1997-07-17 |
| CA2131680A1 (en) | 1995-03-18 |
| KR950008512A (ko) | 1995-04-17 |
| TW410225B (en) | 2000-11-01 |
| ES2098089T3 (es) | 1997-04-16 |
| AU7305894A (en) | 1995-03-30 |
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