DK0634400T3 - Pyridincarboxyimidamidforbindelse og anvendelse deraf - Google Patents
Pyridincarboxyimidamidforbindelse og anvendelse derafInfo
- Publication number
- DK0634400T3 DK0634400T3 DK93902543.3T DK93902543T DK0634400T3 DK 0634400 T3 DK0634400 T3 DK 0634400T3 DK 93902543 T DK93902543 T DK 93902543T DK 0634400 T3 DK0634400 T3 DK 0634400T3
- Authority
- DK
- Denmark
- Prior art keywords
- pyridinecarboxyimidamide
- compound
- effect
- bisalkylsulfonylamino
- nitroxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1334292 | 1992-01-28 | ||
JP6622192 | 1992-03-24 | ||
JP32576092 | 1992-12-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0634400T3 true DK0634400T3 (da) | 1997-04-28 |
Family
ID=27280214
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK93902543.3T DK0634400T3 (da) | 1992-01-28 | 1993-01-28 | Pyridincarboxyimidamidforbindelse og anvendelse deraf |
Country Status (18)
Country | Link |
---|---|
US (1) | US5508293A (no) |
EP (1) | EP0634400B1 (no) |
JP (1) | JP2648395B2 (no) |
KR (1) | KR100249755B1 (no) |
CN (1) | CN1043760C (no) |
AT (1) | ATE151073T1 (no) |
AU (1) | AU674839B2 (no) |
CA (1) | CA2129013C (no) |
DE (1) | DE69309454T2 (no) |
DK (1) | DK0634400T3 (no) |
ES (1) | ES2100522T3 (no) |
FI (1) | FI105399B (no) |
HK (1) | HK1000094A1 (no) |
HU (1) | HU218487B (no) |
MX (1) | MX9300433A (no) |
NO (1) | NO302070B1 (no) |
TW (1) | TW232009B (no) |
WO (1) | WO1993015057A1 (no) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6075024A (en) | 1991-11-27 | 2000-06-13 | Sepracor Inc. | Methods for treating infection using optically pure (S)-lomefloxacin |
WO1997000239A1 (fr) * | 1995-06-14 | 1997-01-03 | Sankyo Company, Limited | Medicament contre l'angine contenant un derive nitroxy comme ingredient actif |
AU5880198A (en) * | 1997-02-14 | 1998-09-08 | Kirin Beer Kabushiki Kaisha | Drugs for relieving peripheral circulation disorder |
US20060293266A1 (en) * | 2000-05-10 | 2006-12-28 | The Trustees Of Columbia | Phosphodiesterase 4D in the ryanodine receptor complex protects against heart failure |
US7393652B2 (en) * | 2000-05-10 | 2008-07-01 | The Trustees Of Columbia University In The City Of New York | Methods for identifying a chemical compound that directly enhances binding of FKBP12.6 to PKA-phosphorylated type 2 ryanodine receptor (RyR2) |
US7718644B2 (en) * | 2004-01-22 | 2010-05-18 | The Trustees Of Columbia University In The City Of New York | Anti-arrhythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) and uses thereof |
US7879840B2 (en) * | 2005-08-25 | 2011-02-01 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
US6489125B1 (en) * | 2000-05-10 | 2002-12-03 | The Trustees Of Columbia University In The City Of New York | Methods for identifying chemical compounds that inhibit dissociation of FKBP12.6 binding protein from type 2 ryanodine receptor |
US20040229781A1 (en) * | 2000-05-10 | 2004-11-18 | Marks Andrew Robert | Compounds and methods for treating and preventing exercise-induced cardiac arrhythmias |
US20040048780A1 (en) * | 2000-05-10 | 2004-03-11 | The Trustees Of Columbia University In The City Of New York | Method for treating and preventing cardiac arrhythmia |
US8022058B2 (en) | 2000-05-10 | 2011-09-20 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
JP2003321329A (ja) * | 2002-04-25 | 2003-11-11 | Kirin Brewery Co Ltd | 育毛剤 |
US7544678B2 (en) * | 2002-11-05 | 2009-06-09 | The Trustees Of Columbia University In The City Of New York | Anti-arrythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) |
JP2007525165A (ja) | 2003-03-07 | 2007-09-06 | トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク | タイプ1ライアノジン受容体に基づく方法 |
US8710045B2 (en) * | 2004-01-22 | 2014-04-29 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the ryanodine receptors |
US7704990B2 (en) * | 2005-08-25 | 2010-04-27 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
TW200908984A (en) | 2007-08-07 | 2009-03-01 | Piramal Life Sciences Ltd | Pyridyl derivatives, their preparation and use |
EP3088390A1 (en) | 2015-04-30 | 2016-11-02 | Bayer CropScience AG | Catalytic hydrogenation of substituted cyanopyridines |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI95244C (fi) * | 1988-12-27 | 1996-01-10 | Kirin Brewery | Analogiamenetelmä valmistaa lääkeaineina käyttökelpoisia uusia karboksimidiamidijohdannaisia tai niiden farmaseuttisesti sopivia happoadditiosuoloja |
JPH0662567B2 (ja) * | 1988-12-27 | 1994-08-17 | 麒麟麦酒株式会社 | ピリジンカルボキシイミダミド誘導体、その製造中間体、製造法および用途 |
JP2846070B2 (ja) * | 1989-11-29 | 1999-01-13 | 麒麟麦酒株式会社 | カルボキシイミダミド誘導体 |
-
1993
- 1993-01-27 MX MX9300433A patent/MX9300433A/es not_active IP Right Cessation
- 1993-01-28 HU HU9402218A patent/HU218487B/hu not_active IP Right Cessation
- 1993-01-28 DE DE69309454T patent/DE69309454T2/de not_active Expired - Fee Related
- 1993-01-28 KR KR1019940702577A patent/KR100249755B1/ko not_active IP Right Cessation
- 1993-01-28 ES ES93902543T patent/ES2100522T3/es not_active Expired - Lifetime
- 1993-01-28 CA CA002129013A patent/CA2129013C/en not_active Expired - Fee Related
- 1993-01-28 US US08/256,625 patent/US5508293A/en not_active Expired - Lifetime
- 1993-01-28 JP JP5513093A patent/JP2648395B2/ja not_active Expired - Fee Related
- 1993-01-28 AT AT93902543T patent/ATE151073T1/de not_active IP Right Cessation
- 1993-01-28 AU AU33677/93A patent/AU674839B2/en not_active Ceased
- 1993-01-28 TW TW082100471A patent/TW232009B/zh active
- 1993-01-28 WO PCT/JP1993/000103 patent/WO1993015057A1/ja active IP Right Grant
- 1993-01-28 EP EP93902543A patent/EP0634400B1/en not_active Expired - Lifetime
- 1993-01-28 DK DK93902543.3T patent/DK0634400T3/da active
- 1993-01-28 CN CN93102390A patent/CN1043760C/zh not_active Expired - Fee Related
-
1994
- 1994-07-22 NO NO942740A patent/NO302070B1/no unknown
- 1994-07-26 FI FI943508A patent/FI105399B/fi active
-
1997
- 1997-07-08 HK HK97101521A patent/HK1000094A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
FI105399B (fi) | 2000-08-15 |
FI943508A (fi) | 1994-09-22 |
CN1077949A (zh) | 1993-11-03 |
KR100249755B1 (ko) | 2000-04-01 |
NO942740L (no) | 1994-09-27 |
CA2129013C (en) | 2001-08-14 |
US5508293A (en) | 1996-04-16 |
EP0634400B1 (en) | 1997-04-02 |
HU9402218D0 (en) | 1994-09-28 |
HU218487B (hu) | 2000-09-28 |
KR950700255A (ko) | 1995-01-16 |
DE69309454D1 (de) | 1997-05-07 |
NO302070B1 (no) | 1998-01-19 |
EP0634400A1 (en) | 1995-01-18 |
CN1043760C (zh) | 1999-06-23 |
FI943508A0 (fi) | 1994-07-26 |
DE69309454T2 (de) | 1997-08-14 |
ATE151073T1 (de) | 1997-04-15 |
TW232009B (no) | 1994-10-11 |
MX9300433A (es) | 1994-07-29 |
AU674839B2 (en) | 1997-01-16 |
WO1993015057A1 (en) | 1993-08-05 |
ES2100522T3 (es) | 1997-06-16 |
NO942740D0 (no) | 1994-07-22 |
AU3367793A (en) | 1993-09-01 |
HK1000094A1 (en) | 1997-11-21 |
CA2129013A1 (en) | 1993-07-29 |
JP2648395B2 (ja) | 1997-08-27 |
EP0634400A4 (en) | 1995-06-14 |
HUT70506A (en) | 1995-10-30 |
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