DK0632033T3 - Nye benzopyranderivater - Google Patents
Nye benzopyranderivaterInfo
- Publication number
- DK0632033T3 DK0632033T3 DK93902526T DK93902526T DK0632033T3 DK 0632033 T3 DK0632033 T3 DK 0632033T3 DK 93902526 T DK93902526 T DK 93902526T DK 93902526 T DK93902526 T DK 93902526T DK 0632033 T3 DK0632033 T3 DK 0632033T3
- Authority
- DK
- Denmark
- Prior art keywords
- benzopyran derivatives
- represent
- hydroxy
- new benzopyran
- hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1081992 | 1992-01-24 | ||
| PCT/JP1993/000086 WO1993015068A1 (en) | 1992-01-24 | 1993-01-25 | Novel benzopyran derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0632033T3 true DK0632033T3 (da) | 1999-10-18 |
Family
ID=11760967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93902526T DK0632033T3 (da) | 1992-01-24 | 1993-01-25 | Nye benzopyranderivater |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5646308A (es) |
| EP (1) | EP0632033B1 (es) |
| JP (1) | JP3260458B2 (es) |
| KR (1) | KR100217167B1 (es) |
| CN (1) | CN1036918C (es) |
| AT (1) | ATE178601T1 (es) |
| AU (1) | AU3367393A (es) |
| CA (1) | CA2128603A1 (es) |
| DE (1) | DE69324354T2 (es) |
| DK (1) | DK0632033T3 (es) |
| ES (1) | ES2132217T3 (es) |
| GR (1) | GR3030581T3 (es) |
| SG (1) | SG52734A1 (es) |
| WO (1) | WO1993015068A1 (es) |
| ZA (1) | ZA93436B (es) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5428031A (en) * | 1991-12-03 | 1995-06-27 | Merck & Co., Inc. | Methods of treating cardiac arrhythmia |
| ATE187331T1 (de) * | 1993-04-23 | 1999-12-15 | Chugai Pharmaceutical Co Ltd | Benzopyranderivate |
| US5719155A (en) * | 1993-11-10 | 1998-02-17 | Japan Tobacco Inc. | Chroman derivative and pharmaceutical use thereof |
| ES2139933T3 (es) * | 1994-08-18 | 2000-02-16 | Merck & Co Inc | 2,3-dihidro-1-(2,2,2-trifluoroetil)-2-oxo-5-fenil-1h-1,4-benzodiacepinas. |
| JPH11506760A (ja) * | 1995-06-07 | 1999-06-15 | メルク エンド カンパニー インコーポレーテッド | 新規なｎ−（２，４−ジオキソ−２，３，４，５−テトラヒドロ−１ｈ−１，５−ベンゾジアゼピン−３イル）−３−アミド |
| US5726171A (en) * | 1995-06-07 | 1998-03-10 | Merck & Co Inc | N-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo B! 1,4!diazepin-3yl)-acetamides |
| US5631251A (en) * | 1995-06-07 | 1997-05-20 | Merck & Co., Inc. | 5-cyclopropyl-1,4 benzodiazepine-2-ones |
| US5700797A (en) * | 1995-06-07 | 1997-12-23 | Merck & Co, Inc. | N-(2,4-dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3-yl)-3-amides |
| US5691331A (en) * | 1995-06-07 | 1997-11-25 | Merck & Co., Inc. | N-(2,4-Dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3yl) -3- amides |
| JP3076066B2 (ja) * | 1996-08-27 | 2000-08-14 | 塩野義製薬株式会社 | クロメン−３−カルボン酸誘導体 |
| FR2756284B1 (fr) * | 1996-11-26 | 2000-04-28 | Adir | Nouveaux derives du benzopyrane, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| TW533073B (en) * | 1997-03-03 | 2003-05-21 | Chugai Pharmaceutical Co Ltd | Therapeutic agents for peripheral vascular disease |
| EP1004316B1 (en) * | 1997-08-08 | 2005-11-02 | Chugai Seiyaku Kabushiki Kaisha | Therapeutics for diabetic complications |
| WO2000018754A1 (fr) * | 1998-09-30 | 2000-04-06 | Chugai Seiyaku Kabushiki Kaisha | Procedes de preparation de derives de benzopyranne 4-substitue |
| CZ20013076A3 (cs) * | 2000-08-29 | 2002-04-17 | Kuraray Co., Ltd. | Způsob výroby chromankarboxylové kyseliny |
| KR100602191B1 (ko) * | 2004-03-10 | 2006-07-19 | 한국화학연구원 | 5-라이폭시게네이즈 저해활성을 가지는2,2'-이중치환-3,4-디하이드로-7,8-이중치환-6-알킬아미노벤조피란 유도체 |
| WO2005105776A1 (en) * | 2004-05-05 | 2005-11-10 | F. Hoffmann-La Roche Ag | Arylsulfonyl benzodioxanes useful for modulation the 5-ht6 receptor, the 5-ht2areceptor or both |
| US8604222B2 (en) | 2004-07-30 | 2013-12-10 | Forest Laboratories Holdings Limited | Nebivolol and its pharmaceutically acceptable salts, process for preparation and pharmaceutical compositions of nebivolol |
| BRPI0519709A2 (pt) * | 2004-12-21 | 2009-03-10 | Hoffmann La Roche | derivados de tetralina e indano e usos dos mesmos como antagonistas de 5-ht |
| WO2006066745A1 (en) * | 2004-12-21 | 2006-06-29 | F.Hoffmann-La Roche Ag | Tetralin and indane derivatives and uses thereof |
| CN101119965B (zh) * | 2004-12-21 | 2012-09-26 | 弗·哈夫曼-拉罗切有限公司 | 萘满和茚满衍生物及其用途 |
| JP4738418B2 (ja) | 2004-12-21 | 2011-08-03 | エフ．ホフマン−ラ ロシュ アーゲー | クロマン誘導体及びｃｎｓ障害の処置におけるその使用 |
| CA2592001A1 (en) * | 2004-12-21 | 2006-06-29 | F. Hoffmann-La Roche Ag | Chroman derivatives and their use as 5-ht receptor ligands |
| KR100704009B1 (ko) * | 2005-08-30 | 2007-04-04 | 한국화학연구원 | 염증억제 활성을 가지는6-알킬아미노-2-메틸-2'-(ｎ-메틸치환술폰아미도)메틸-2ｈ-1-벤조피란 유도체 |
| KR100984897B1 (ko) * | 2005-11-03 | 2010-10-01 | 에프. 호프만-라 로슈 아게 | 5-ｈｔ6 억제제로서 아릴설포닐 크로만 |
| WO2007147763A1 (en) * | 2006-06-20 | 2007-12-27 | F. Hoffmann-La Roche Ag | Arylsulfonyl naphthalene derivatives and uses thereof |
| BRPI0713502A2 (pt) * | 2006-06-20 | 2012-03-13 | F. Hoffmann-La Roche Ag | derivados de tetralina de arilsulfonamidil e empregos destes |
| AU2007263084A1 (en) * | 2006-06-20 | 2007-12-27 | F. Hoffmann-La Roche Ag | Tetralin and indane derivatives and uses thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH619701A5 (es) * | 1975-08-07 | 1980-10-15 | Bayer Ag | |
| JPS57167981A (en) * | 1981-04-08 | 1982-10-16 | Kowa Co | Benzopyran derivative |
| GB8911280D0 (en) * | 1989-05-17 | 1989-07-05 | Beecham Group Plc | Novel compounds |
| AU8230891A (en) * | 1990-07-27 | 1992-03-02 | Chugai Seiyaku Kabushiki Kaisha | Novel benzopyran derivative |
-
1993
- 1993-01-21 ZA ZA93436A patent/ZA93436B/xx unknown
- 1993-01-22 CN CN93102056A patent/CN1036918C/zh not_active Expired - Fee Related
- 1993-01-22 JP JP00942193A patent/JP3260458B2/ja not_active Expired - Fee Related
- 1993-01-25 DK DK93902526T patent/DK0632033T3/da active
- 1993-01-25 ES ES93902526T patent/ES2132217T3/es not_active Expired - Lifetime
- 1993-01-25 WO PCT/JP1993/000086 patent/WO1993015068A1/ja active IP Right Grant
- 1993-01-25 AU AU33673/93A patent/AU3367393A/en not_active Abandoned
- 1993-01-25 KR KR1019940702541A patent/KR100217167B1/ko not_active IP Right Cessation
- 1993-01-25 US US08/256,580 patent/US5646308A/en not_active Expired - Fee Related
- 1993-01-25 AT AT93902526T patent/ATE178601T1/de not_active IP Right Cessation
- 1993-01-25 SG SG1996008501A patent/SG52734A1/en unknown
- 1993-01-25 EP EP93902526A patent/EP0632033B1/en not_active Expired - Lifetime
- 1993-01-25 CA CA002128603A patent/CA2128603A1/en not_active Abandoned
- 1993-01-25 DE DE69324354T patent/DE69324354T2/de not_active Expired - Fee Related
-
1999
- 1999-06-22 GR GR990401664T patent/GR3030581T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH05294954A (ja) | 1993-11-09 |
| ZA93436B (en) | 1993-08-25 |
| GR3030581T3 (en) | 1999-10-29 |
| SG52734A1 (en) | 1998-09-28 |
| CA2128603A1 (en) | 1993-08-05 |
| DE69324354D1 (de) | 1999-05-12 |
| KR950700277A (ko) | 1995-01-16 |
| WO1993015068A1 (en) | 1993-08-05 |
| CN1036918C (zh) | 1998-01-07 |
| CN1077954A (zh) | 1993-11-03 |
| DE69324354T2 (de) | 1999-11-25 |
| KR100217167B1 (ko) | 1999-09-01 |
| EP0632033A1 (en) | 1995-01-04 |
| US5646308A (en) | 1997-07-08 |
| AU3367393A (en) | 1993-09-01 |
| EP0632033B1 (en) | 1999-04-07 |
| JP3260458B2 (ja) | 2002-02-25 |
| EP0632033A4 (es) | 1995-02-01 |
| ES2132217T3 (es) | 1999-08-16 |
| ATE178601T1 (de) | 1999-04-15 |
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