DK0623588T3 - Forbedret fremgangsmåde til fremstilling af L-(-)-carnitin fra affaldsprodukter med modsat konfigur ation - Google Patents
Forbedret fremgangsmåde til fremstilling af L-(-)-carnitin fra affaldsprodukter med modsat konfigur ationInfo
- Publication number
- DK0623588T3 DK0623588T3 DK94830152.8T DK94830152T DK0623588T3 DK 0623588 T3 DK0623588 T3 DK 0623588T3 DK 94830152 T DK94830152 T DK 94830152T DK 0623588 T3 DK0623588 T3 DK 0623588T3
- Authority
- DK
- Denmark
- Prior art keywords
- carnitine
- preparing
- improved method
- waste products
- opposite configuration
- Prior art date
Links
- PHIQHXFUZVPYII-UHFFFAOYSA-N carnitine Chemical compound C[N+](C)(C)CC(O)CC([O-])=O PHIQHXFUZVPYII-UHFFFAOYSA-N 0.000 title abstract 4
- 239000002699 waste material Substances 0.000 title 1
- 150000002596 lactones Chemical class 0.000 abstract 2
- PHIQHXFUZVPYII-LURJTMIESA-N (S)-carnitine Chemical compound C[N+](C)(C)C[C@@H](O)CC([O-])=O PHIQHXFUZVPYII-LURJTMIESA-N 0.000 abstract 1
- 238000005903 acid hydrolysis reaction Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/32—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/02—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D305/10—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having one or more double bonds between ring members or between ring members and non-ring members
- C07D305/12—Beta-lactones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Processing Of Solid Wastes (AREA)
- Fertilizers (AREA)
- Switches Operated By Changes In Physical Conditions (AREA)
- Lighting Device Outwards From Vehicle And Optical Signal (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITRM930226A IT1261230B (it) | 1993-04-08 | 1993-04-08 | Procedimento migliorato per la preparazione di l-(-)-carnitina a partire da suoi precursori aventi opposta configurazione. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0623588T3 true DK0623588T3 (da) | 1997-07-21 |
Family
ID=11401703
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94830152.8T DK0623588T3 (da) | 1993-04-08 | 1994-03-31 | Forbedret fremgangsmåde til fremstilling af L-(-)-carnitin fra affaldsprodukter med modsat konfigur ation |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5491260A (enExample) |
| EP (1) | EP0623588B1 (enExample) |
| JP (1) | JP3502657B2 (enExample) |
| KR (1) | KR100301951B1 (enExample) |
| AT (1) | ATE150003T1 (enExample) |
| CA (1) | CA2120811C (enExample) |
| DE (1) | DE69401979T2 (enExample) |
| DK (1) | DK0623588T3 (enExample) |
| ES (1) | ES2099563T3 (enExample) |
| GR (1) | GR3023594T3 (enExample) |
| HK (1) | HK1005867A1 (enExample) |
| IT (1) | IT1261230B (enExample) |
| TW (1) | TW275613B (enExample) |
| ZA (1) | ZA942428B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1261828B (it) | 1993-07-14 | 1996-06-03 | Sigma Tau Ind Farmaceuti | Esteri di acil l-carnitine e composizioni farmaceutiche che li contengono per il trattamento dello shock endotossico. |
| IT1276207B1 (it) * | 1995-09-29 | 1997-10-27 | Sigma Tau Ind Farmaceuti | Procedimento per la preparazione del (s)-b-idrossi-gamma- butirrolattone |
| KR100255039B1 (ko) * | 1997-07-28 | 2000-05-01 | 박영구 | L-카르니틴의제조방법 |
| IT1297120B1 (it) * | 1997-12-16 | 1999-08-03 | Sigma Tau Ind Farmaceuti | Procedimento per la produzione di (r)-3-idrossi-4-butirrolattone utile nella preparazione della (r)-carnitina |
| DE10027391B4 (de) * | 2000-06-02 | 2006-05-04 | Wella Ag | Oligomere und Polymere aus Crotonbetain oder Crotonbetainderivaten |
| EP2409972A1 (en) * | 2010-07-21 | 2012-01-25 | Lonza Ltd. | A process for the production of carnitine from B-lactones |
| JP6034287B2 (ja) * | 2010-07-21 | 2016-11-30 | ロンザ リミテッドＬｏｎｚａ Ｌｉｍｉｔｅｄ | β−ラクトンからのカルニチンの製造のためのプロセス |
| EP2468739A1 (en) * | 2010-12-22 | 2012-06-27 | Lonza Ltd. | A process for the production of carnitine from B-lactones |
| EP2409965A1 (en) * | 2010-07-21 | 2012-01-25 | Lonza Ltd. | A process for the production of carnitine by cycloaddition |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE664500A (enExample) * | ||||
| ES332080A1 (es) * | 1965-10-15 | 1967-10-01 | Otsuka Pharma Co Ltd | Procedimiento para obtencion de complejos de sales opticamente activas de hidroxido de nitrilo,carnitina y acidos glutamicos n-acilos. |
| IT1156852B (it) * | 1978-07-10 | 1987-02-04 | Sigma Tau Ind Farmaceuti | Procedimento industriale per la preparazione del d'canforato della l carnitinammide e del d canforato della d carnitinammide e sue applicazioni |
| IT1136945B (it) * | 1981-03-18 | 1986-09-03 | Anic Spa | Processo per la preparazione di l-carnitina |
| JPS59183694A (ja) * | 1983-04-05 | 1984-10-18 | Hamari Yakuhin Kogyo Kk | 光学活性なカルニチンの生化学的製造法 |
| JPS59192095A (ja) * | 1983-04-13 | 1984-10-31 | Ajinomoto Co Inc | Ｌ−カルニチンの製造法 |
| DD221905B1 (de) * | 1983-11-03 | 1987-03-18 | Univ Leipzig | Verfahren zur herstellung von l(-)-carnitin und seinen derivaten |
| CH664374A5 (de) * | 1985-02-27 | 1988-02-29 | Lonza Ag | Verfahren zur herstellung von l-carnitin auf mikrobiologischem weg. |
| US5200526A (en) * | 1987-04-27 | 1993-04-06 | The Governors Of The University Of Alberta | Syntheses of optically pure α-amino acids from 3-amino-2-oxetanone salts |
| JPH0291049A (ja) * | 1988-09-21 | 1990-03-30 | Lonza Ag | ｒ―ブチロベタインの製造方法 |
| IT1231751B (it) * | 1989-04-12 | 1991-12-21 | Sigma Tau Ind Farmaceuti | Procedimento per la produzione di r(+) amminocarnitina e s(-) amminocarnitina |
| MX170707B (es) * | 1989-07-28 | 1993-09-08 | Lonza Ag | Procedimiento para la produccion discontinua de l-carnitina por transformacion microbiologica de crotonobetaina y gama-butirobetaina |
| IT1240833B (it) * | 1990-05-14 | 1993-12-17 | Sigma Tau Ind Farmaceuti | Procedimento biocatalitico per la produzione di l-(-)- carnitina da crotonilbetaina e ceppi di proteeae per l'uso in tale procedimento |
| IT1245699B (it) * | 1991-05-29 | 1994-10-14 | Sigma Tau Ind Farmaceuti | Derivati della l-carnitina quali agenti terapeutici per il trattamento delle miopatie, della degenarazione neuronale e per inibire la proteolisi |
| IT1256705B (it) * | 1992-12-21 | 1995-12-12 | Sigma Tau Ind Farmaceuti | Procedimento per la preparazione di l-(-)-carnitina a partire da un prodotto di scarto avente opposta configurazione. |
-
1993
- 1993-04-08 IT ITRM930226A patent/IT1261230B/it active IP Right Grant
-
1994
- 1994-03-31 AT AT94830152T patent/ATE150003T1/de active
- 1994-03-31 ES ES94830152T patent/ES2099563T3/es not_active Expired - Lifetime
- 1994-03-31 DK DK94830152.8T patent/DK0623588T3/da active
- 1994-03-31 DE DE69401979T patent/DE69401979T2/de not_active Expired - Lifetime
- 1994-03-31 EP EP94830152A patent/EP0623588B1/en not_active Expired - Lifetime
- 1994-04-07 JP JP06928994A patent/JP3502657B2/ja not_active Expired - Fee Related
- 1994-04-07 US US08/224,522 patent/US5491260A/en not_active Expired - Lifetime
- 1994-04-07 CA CA002120811A patent/CA2120811C/en not_active Expired - Fee Related
- 1994-04-08 ZA ZA942428A patent/ZA942428B/xx unknown
- 1994-04-08 KR KR1019940007343A patent/KR100301951B1/ko not_active Expired - Fee Related
- 1994-04-19 TW TW083103475A patent/TW275613B/zh not_active IP Right Cessation
-
1997
- 1997-05-30 GR GR970401237T patent/GR3023594T3/el unknown
-
1998
- 1998-06-05 HK HK98104946A patent/HK1005867A1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0623588A1 (en) | 1994-11-09 |
| DE69401979T2 (de) | 1997-06-26 |
| IT1261230B (it) | 1996-05-09 |
| ES2099563T3 (es) | 1997-05-16 |
| ITRM930226A0 (it) | 1993-04-08 |
| ATE150003T1 (de) | 1997-03-15 |
| TW275613B (enExample) | 1996-05-11 |
| EP0623588B1 (en) | 1997-03-12 |
| HK1005867A1 (en) | 1999-01-29 |
| JP3502657B2 (ja) | 2004-03-02 |
| US5491260A (en) | 1996-02-13 |
| JPH06311888A (ja) | 1994-11-08 |
| ITRM930226A1 (it) | 1994-10-08 |
| ZA942428B (en) | 1994-11-29 |
| KR100301951B1 (ko) | 2001-10-22 |
| CA2120811C (en) | 2004-10-26 |
| CA2120811A1 (en) | 1994-10-09 |
| DE69401979D1 (de) | 1997-04-17 |
| GR3023594T3 (en) | 1997-08-29 |
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