DK0594772T3 - - Google Patents

Info

Publication number
DK0594772T3
DK0594772T3 DK92916161.0T DK92916161T DK0594772T3 DK 0594772 T3 DK0594772 T3 DK 0594772T3 DK 92916161 T DK92916161 T DK 92916161T DK 0594772 T3 DK0594772 T3 DK 0594772T3
Authority
DK
Denmark
Prior art keywords
carrier molecule
attached
group
reagents
divinyl sulfone
Prior art date
Application number
DK92916161.0T
Other languages
Danish (da)
English (en)
Inventor
Allan Otto Fog Lihme
Thomas Boenisch
Original Assignee
Immunodex K S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26065568&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0594772(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DK911309A external-priority patent/DK130991D0/da
Application filed by Immunodex K S filed Critical Immunodex K S
Application granted granted Critical
Publication of DK0594772T3 publication Critical patent/DK0594772T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
DK92916161.0T 1991-07-04 1992-06-29 DK0594772T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK911309A DK130991D0 (da) 1991-07-04 1991-07-04 Polymere konjugater
US07/789,757 US5543332A (en) 1991-07-04 1991-11-08 Water-soluble, polymer-based reagents and conjugates comprising moieties derived from divinyl sulfone

Publications (1)

Publication Number Publication Date
DK0594772T3 true DK0594772T3 (es) 1997-02-24

Family

ID=26065568

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92916161.0T DK0594772T3 (es) 1991-07-04 1992-06-29

Country Status (12)

Country Link
EP (1) EP0594772B1 (es)
JP (1) JP3340434B2 (es)
AT (1) ATE142021T1 (es)
AU (1) AU667051B2 (es)
CA (1) CA2112992C (es)
DE (1) DE69213240T2 (es)
DK (1) DK0594772T3 (es)
ES (1) ES2094920T3 (es)
FI (1) FI115413B (es)
GR (1) GR3021806T3 (es)
NO (1) NO315443B1 (es)
WO (1) WO1993001498A1 (es)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6552170B1 (en) * 1990-04-06 2003-04-22 Amgen Inc. PEGylation reagents and compounds formed therewith
US5773227A (en) * 1993-06-23 1998-06-30 Molecular Probes, Inc. Bifunctional chelating polysaccharides
US5446090A (en) * 1993-11-12 1995-08-29 Shearwater Polymers, Inc. Isolatable, water soluble, and hydrolytically stable active sulfones of poly(ethylene glycol) and related polymers for modification of surfaces and molecules
WO1995032305A1 (en) 1994-05-19 1995-11-30 Dako A/S Pna probes for detection of neisseria gonorrhoeae and chlamydia trachomatis
US5888733A (en) * 1995-11-16 1999-03-30 Dako A/S In situ hybridization to detect specific nucleic acid sequences in eucaryotic samples
US5747639A (en) * 1996-03-06 1998-05-05 Amgen Boulder Inc. Use of hydrophobic interaction chromatography to purify polyethylene glycols
US6309646B1 (en) * 1996-05-09 2001-10-30 The Henry M. Jackson Foundation For The Advancement Of Military Medicine Protein-polysaccharide conjugate vaccines and other immunological reagents prepared using homobifunctional and heterobifunctional vinylsulfones, and processes for preparing the conjugates
TW555765B (en) 1996-07-09 2003-10-01 Amgen Inc Low molecular weight soluble tumor necrosis factor type-I and type-II proteins
GB9624165D0 (en) 1996-11-19 1997-01-08 Amdex A S Use of nucleic acids bound to carrier macromolecules
ES2207759T3 (es) 1996-12-06 2004-06-01 Amgen Inc. Terapia de combinacion que utiliza una proteina de union del factor de necrosis tumoral (tnf) en el tratamiento de enfermedades inducidas por el tnf.
US6709873B1 (en) * 1997-04-09 2004-03-23 Isodiagnostika Inc. Method for production of antibodies to specific sites of rapamycin
US5994089A (en) * 1997-05-16 1999-11-30 Coulter International Corp. Simultaneous analyses of white blood cell subsets using multi-color, multi-intensity fluorescent markers in flow cytometry
US6066446A (en) * 1997-12-19 2000-05-23 Nen Life Science Products, Inc. Assay member and method for its manufacture
WO1999040438A1 (en) * 1998-02-03 1999-08-12 Synbiotics Corporation Device and method to detect immunoprotective antibody titers
ATE268905T1 (de) * 1998-07-30 2004-06-15 Oakville Trading Hong Kong Ltd Verfahren zur herstellung von wasserlöslichen vernetzten conjugate
WO2000022000A1 (en) * 1998-10-09 2000-04-20 Isotechnika, Inc. Methods for the production of antibodies to specific regions of cyclosporine and cyclosporine metabolites
US6686454B1 (en) * 1998-10-09 2004-02-03 Isotechnika, Inc. Antibodies to specific regions of cyclosporine related compounds
JP3781934B2 (ja) 1999-12-22 2006-06-07 株式会社ニチレイバイオサイエンス 酵素−タンパク質複合体
DE10039112A1 (de) * 2000-08-07 2002-03-07 Pe Diagnostik Gmbh Verfahren zum Herstellen von Antikörper aus einer verunreinigten Antigenlösung
GB0029617D0 (en) * 2000-12-05 2001-01-17 Norchip As Ligand detection method
WO2002072631A2 (en) 2001-03-14 2002-09-19 Dakocytomation Denmark A/S Mhc molecule constructs and their usesfor diagnosis and therapy
US7034127B2 (en) * 2002-07-02 2006-04-25 Genzyme Corporation Hydrophilic biopolymer-drug conjugates, their preparation and use
EP1405907A3 (en) * 2002-07-22 2004-10-13 Roche Diagnostics GmbH Conjugate of a tissue non-specific alkaline phosphatase and dextran, process for its production and use thereof
CA2433479A1 (en) 2002-07-22 2004-01-22 F. Hoffmann-La Roche Ag Conjugate of a tissue non-specific alkaline phosphatase and dextran, process for its production and use thereof
JP2007512542A (ja) * 2003-12-01 2007-05-17 デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング 複合体、及び検出方法におけるそれらの使用
CA2547351A1 (en) 2003-12-01 2005-07-07 Dade Behring Marburg Gmbh Homogeneous detection method
JP4949038B2 (ja) 2003-12-01 2012-06-06 ダコ デンマーク アクティーゼルスカブ 免疫組織化学的検出のための方法および組成物
GB0426823D0 (en) 2004-12-07 2005-01-12 Precisense As Sensor for detection of glucose
GB0426822D0 (en) 2004-12-07 2005-01-12 Precisense As Sensor for detection of glucose
CA2612227C (en) 2005-06-14 2014-04-22 Taigen Biotechnology Co., Ltd. Pyrimidine compounds
US8193206B2 (en) 2005-06-14 2012-06-05 Taigen Biotechnology Co., Ltd. Pyrimidine compounds
DE112006003813T5 (de) 2006-03-20 2009-01-22 Inverness Medical Switzerland Gmbh Wasserlösliche Konjugate zur elektrochemischen Detektion
EP2361930A3 (en) * 2007-03-26 2011-10-26 Dako Denmark A/S Multimers of MHC-peptide complexes and uses thereof in Borrelia infectious diseases
EP2167536A1 (en) 2007-07-03 2010-03-31 Dako Denmark A/S Mhc multimers, methods for their generation, labeling and use
EP2197908A2 (en) 2007-09-27 2010-06-23 Dako Denmark A/S Mhc multimers in tuberculosis diagnostics, vaccine and therapeutics
US10968269B1 (en) 2008-02-28 2021-04-06 Agilent Technologies, Inc. MHC multimers in borrelia diagnostics and disease
US8372849B2 (en) 2008-04-21 2013-02-12 Taigen Biotechnology Co., Ltd. Heterocyclic compounds
WO2010009735A2 (en) 2008-07-23 2010-01-28 Dako Denmark A/S Combinatorial analysis and repair
WO2010031749A1 (en) 2008-09-17 2010-03-25 Innate Pharma Compositions and methods for detecting tlr3
GB0817244D0 (en) 2008-09-20 2008-10-29 Univ Cardiff Use of a protein kinase inhibitor to detect immune cells, such as T cells
US10369204B2 (en) 2008-10-02 2019-08-06 Dako Denmark A/S Molecular vaccines for infectious disease
WO2010056847A2 (en) 2008-11-13 2010-05-20 Taigen Biotechnology Co., Ltd. Lyophilization formulation
EP2270506A3 (en) * 2009-07-02 2011-03-09 Amic AB Amplified labeled conjugate for use in immunoassays
WO2011050938A1 (de) 2009-10-26 2011-05-05 Genovoxx Gmbh Konjugate von nukleotiden und methoden zu deren anwendung
US10323279B2 (en) 2012-08-14 2019-06-18 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10752949B2 (en) 2012-08-14 2020-08-25 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9701998B2 (en) 2012-12-14 2017-07-11 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9951386B2 (en) 2014-06-26 2018-04-24 10X Genomics, Inc. Methods and systems for processing polynucleotides
US11591637B2 (en) 2012-08-14 2023-02-28 10X Genomics, Inc. Compositions and methods for sample processing
US10273541B2 (en) 2012-08-14 2019-04-30 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10400280B2 (en) 2012-08-14 2019-09-03 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9567631B2 (en) 2012-12-14 2017-02-14 10X Genomics, Inc. Methods and systems for processing polynucleotides
CA3216609A1 (en) 2012-08-14 2014-02-20 10X Genomics, Inc. Microcapsule compositions and methods
US10533221B2 (en) 2012-12-14 2020-01-14 10X Genomics, Inc. Methods and systems for processing polynucleotides
WO2014124338A1 (en) 2013-02-08 2014-08-14 10X Technologies, Inc. Polynucleotide barcode generation
WO2014208776A1 (ja) 2013-06-28 2014-12-31 国立大学法人九州大学 タンパク質－ポリマ複合体、ＴＧａｓｅ基質含有ポリマ、ＴＧａｓｅ基質含有モノマ、タンパク質－ポリマ複合体の製造方法、および固液の界面あるいは界面近傍でタンパク質機能を高める方法
CN114534806B (zh) 2014-04-10 2024-03-29 10X基因组学有限公司 用于封装和分割试剂的流体装置、系统和方法及其应用
EP4270006A3 (en) 2014-06-13 2024-01-10 Immudex ApS General detection and isolation of specific cells by binding of labeled molecules
WO2015200893A2 (en) 2014-06-26 2015-12-30 10X Genomics, Inc. Methods of analyzing nucleic acids from individual cells or cell populations
KR102321863B1 (ko) 2015-01-12 2021-11-08 10엑스 제노믹스, 인크. 핵산 시퀀싱 라이브러리의 제조 방법 및 시스템 및 이를 이용하여 제조한 라이브러리
EP4286516A3 (en) 2015-02-24 2024-03-06 10X Genomics, Inc. Partition processing methods and systems
SG10202108763UA (en) 2015-12-04 2021-09-29 10X Genomics Inc Methods and compositions for nucleic acid analysis
CA3017412A1 (en) 2016-03-15 2017-09-21 Mipsalus Aps A method for qualitative or quantitative determination of the presence of an analyte in a sample
US10011872B1 (en) 2016-12-22 2018-07-03 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10550429B2 (en) 2016-12-22 2020-02-04 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10815525B2 (en) 2016-12-22 2020-10-27 10X Genomics, Inc. Methods and systems for processing polynucleotides
CN117512066A (zh) 2017-01-30 2024-02-06 10X基因组学有限公司 用于基于微滴的单细胞条形编码的方法和系统
US20180340169A1 (en) 2017-05-26 2018-11-29 10X Genomics, Inc. Single cell analysis of transposase accessible chromatin
EP4230746A3 (en) 2017-05-26 2023-11-01 10X Genomics, Inc. Single cell analysis of transposase accessible chromatin
SG11201913654QA (en) 2017-11-15 2020-01-30 10X Genomics Inc Functionalized gel beads
US10829815B2 (en) 2017-11-17 2020-11-10 10X Genomics, Inc. Methods and systems for associating physical and genetic properties of biological particles
EP3752832A1 (en) 2018-02-12 2020-12-23 10X Genomics, Inc. Methods characterizing multiple analytes from individual cells or cell populations
EP3775271A1 (en) 2018-04-06 2021-02-17 10X Genomics, Inc. Systems and methods for quality control in single cell processing
US10871485B2 (en) 2018-04-13 2020-12-22 Rarecyte, Inc. Kits for labeling of biomarkers and methods of using the same
US11965882B2 (en) 2020-01-31 2024-04-23 Cell.Copedia GmbH Methods of isolating a biological entity
CN111965341B (zh) * 2020-08-10 2023-04-11 武汉菲恩生物科技有限公司 一种基于葡聚糖的HRP-羊抗鼠IgG标记抗体及其制备方法
US20230296611A1 (en) 2020-08-10 2023-09-21 Innate Pharma Cell surface mica and micb detection using antibodies
AU2022255908A1 (en) 2021-04-05 2023-10-05 Innate Pharma Immunohistochemistry methods and kir3dl2-specific reagents
CN115537410A (zh) * 2022-09-27 2022-12-30 凯莱英医药化学（阜新）技术有限公司 酶固定化载体及其制备方法、固定化酶及其制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2712344C2 (de) * 1977-03-21 1982-09-23 Hans Dr. 4803 Steinhagen Bünemann Löslicher Komplexbildner für die affinitätsspezifische Trennung von Nukleinsäuren
SE7812237L (sv) * 1978-11-28 1980-05-29 Pharmacia Diagnostics Ab Koncentrationsbestemning av substanser med formaga att biospecifikt binda molekyler med biologiskt ursprung
FR2453847B1 (fr) * 1979-04-13 1985-08-16 Anvar Procede pour l'obtention d'ampholytes porteurs utilisables dans les diverses techniques d'electrofocalisation
US4752339A (en) * 1983-10-31 1988-06-21 Hi-Tek Polymers, Inc. Thixotropic aqueous solutions containing a divinylsulfone-crosslinked polygalactomannan gum
US4780409A (en) * 1985-05-02 1988-10-25 Genetic Systems Corporation Thermally induced phase separation immunoassay
US4778751A (en) * 1986-05-12 1988-10-18 Diagnostic Products Corporation Method for measuring antigens or antibodies in biological fluids using ligand labeled antigens or ligand labeled antibodies
CA1304682C (en) * 1986-11-19 1992-07-07 Nobuo Monji Membrane affinity concentration immunoassay
AU609241B2 (en) * 1988-01-29 1991-04-26 Abbott Laboratories Ion-capture assays and devices
CA1341592C (en) * 1989-07-07 2009-04-14 Abbott Laboratories Ion capture reagents and methods for performing binding assays

Also Published As

Publication number Publication date
NO940030D0 (no) 1994-01-04
EP0594772A1 (en) 1994-05-04
CA2112992A1 (en) 1993-01-21
EP0594772B1 (en) 1996-08-28
DE69213240T2 (de) 1997-04-24
NO315443B1 (no) 2003-09-01
JPH06509167A (ja) 1994-10-13
JP3340434B2 (ja) 2002-11-05
DE69213240D1 (de) 1996-10-02
WO1993001498A1 (en) 1993-01-21
ES2094920T3 (es) 1997-02-01
CA2112992C (en) 2002-06-11
GR3021806T3 (en) 1997-02-28
AU667051B2 (en) 1996-03-07
NO940030L (no) 1994-03-03
FI115413B (fi) 2005-04-29
AU2348992A (en) 1993-02-11
FI940023A0 (fi) 1994-01-04
ATE142021T1 (de) 1996-09-15
FI940023A (fi) 1994-02-25

Similar Documents

Publication Publication Date Title
DK0594772T3 (es)
EP0154884A2 (en) Nucleic acid-protein conjugate
US5650334A (en) Fluorescent labelling compositions and methods for their use
US5728588A (en) Coating of hydrophobic surfaces to render them protein resistant while permitting covalent attachment of specific ligands
Nakamura et al. Detection and removal of Escherichia coli using fluorescein isothiocyanate conjugated monoclonal antibody immobilized on bacterial magnetic particles
CN1323294C (zh) 制备水溶性交联轭合物的方法
CA1341592C (en) Ion capture reagents and methods for performing binding assays
JP3124018B2 (ja) 結合アッセイ用固相の調製方法
EP0040365B1 (en) An assaying method involving biospecific affinity reactions
US4670380A (en) Assays utilizing labeled nucleic acid probes
EP0397113A3 (de) Verfahren zum Nachweis spezifisch bindefähiger Substanzen in Körperflüssigkeiten
WO2007137418A1 (en) Polymer backbone element tags
Ngo Facile activation of Sepharose hydroxyl groups by 2-fluoro-1 methylpyridinium toluene-4-sulfonate: preparation of affinity and covalent chromatographic matrices
KR920015133A (ko) 숙신이미드함유 중합체로 생물학적 활성 시약을 제조하는 방법, 분석 요소 및 이것의 사용방법
EP0236358A1 (en) Method for enhancing and/or accelerating immunoassay detection of human carcinoma tumor associated antigen in a pathology sample
JPH05504481A (ja) 改良された抗体―酵素直接接合体及びその製造方法
WO2002081739A2 (en) Non-enzymatic liposome-linked closely spaced array electrodes assay (nel-ela) for detecting and quantifying nucleic acids
EP0256117A1 (en) Latex agglutination using avidin/biotin system
US5225516A (en) Polymers
WO1995025282A1 (en) Ion-capture reagents and methods for performing binding assays
Montesano et al. Wheat germ cytoplasmic ribosomes. Localization of 7-methylguanosine and 6-methyladenosine by electron microscopy of immune complexes.
CN116953222A (zh) 一种纳米聚合酶标记抗体及其制备方法和应用
WO1999004042A1 (en) Synthetic oligonucleotide-peptide conjugates and methods of use
WO1988008981A1 (en) Immobilization of receptor molecules to hydrophobic water soluble polymer in separation methods on assays
Wilchek et al. [36] Affinity cytochemistry