DK0589898T3 - Produktion af polyhydroxyalkanoat i planter - Google Patents

Produktion af polyhydroxyalkanoat i planter

Info

Publication number
DK0589898T3
DK0589898T3 DK92908920T DK92908920T DK0589898T3 DK 0589898 T3 DK0589898 T3 DK 0589898T3 DK 92908920 T DK92908920 T DK 92908920T DK 92908920 T DK92908920 T DK 92908920T DK 0589898 T3 DK0589898 T3 DK 0589898T3
Authority
DK
Denmark
Prior art keywords
polyhydroxyalkanoate
plant
plants
production
organisms
Prior art date
Application number
DK92908920T
Other languages
Danish (da)
English (en)
Inventor
Simon William Jonathan Bright
David Byrom
Philip Anthony Fentem
Original Assignee
Metabolix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolix Inc filed Critical Metabolix Inc
Application granted granted Critical
Publication of DK0589898T3 publication Critical patent/DK0589898T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C12P7/625—Polyesters of hydroxy carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Biological Depolymerization Polymers (AREA)
DK92908920T 1991-04-24 1992-04-23 Produktion af polyhydroxyalkanoat i planter DK0589898T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919108756A GB9108756D0 (en) 1991-04-24 1991-04-24 Production of polyalkanoate in plants
PCT/GB1992/000742 WO1992019747A1 (en) 1991-04-24 1992-04-23 Production of polyhydroxyalkanoate in plants

Publications (1)

Publication Number Publication Date
DK0589898T3 true DK0589898T3 (da) 2002-11-18

Family

ID=10693835

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92908920T DK0589898T3 (da) 1991-04-24 1992-04-23 Produktion af polyhydroxyalkanoat i planter

Country Status (11)

Country Link
US (2) US5502273A (de)
EP (2) EP1176207B1 (de)
JP (1) JPH06510422A (de)
AT (2) ATE435295T1 (de)
AU (1) AU655816B2 (de)
CA (1) CA2109221C (de)
DE (2) DE69232694T2 (de)
DK (1) DK0589898T3 (de)
ES (2) ES2182819T3 (de)
GB (1) GB9108756D0 (de)
WO (1) WO1992019747A1 (de)

Families Citing this family (64)

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US5245023A (en) 1987-06-29 1993-09-14 Massachusetts Institute Of Technology Method for producing novel polyester biopolymers
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US5610041A (en) * 1991-07-19 1997-03-11 Board Of Trustees Operating Michigan State University Processes for producing polyhydroxybutyrate and related polyhydroxyalkanoates in the plastids of higher plants
ATE295891T1 (de) * 1991-07-19 2005-06-15 Univ Michigan State Transgene pflanzen die polyhydroxyalkanoate produzieren
AU5676394A (en) * 1992-11-20 1994-06-22 Agracetus, Inc. Transgenic cotton plants producing heterologous bioplastic
EP0728213B2 (de) * 1993-11-09 2008-12-10 E.I. Du Pont De Nemours And Company Transgene fruktan - anreichernde nutzpflanzen und verfahren zu ihrer herstellung
ZA95627B (en) * 1994-01-28 1995-10-05 Procter & Gamble Biodegradable copolymers and plastic articles comprising biodegradable copolymers
SG49096A1 (en) * 1994-01-28 1998-05-18 Procter & Gamble Biodegradable 3-polyhydtoxybuyrate/3- polyhydroxyhexanoate copolymer films
ID23491A (id) * 1994-01-28 1995-09-07 Procter & Gamble Kopolimer-kopolimer yang dapat dibiodegradasi dan baha-bahan plastik yang terdiri dari kopolimer-kopolimer yang dapat dibiodegradasi
PL181098B1 (pl) * 1994-01-28 2001-05-31 Procter & Gamble Wyrób absorbujący i kopolimer ulegający biodegradacji
CN1079835C (zh) * 1994-06-01 2002-02-27 普罗克特和甘保尔公司 利用空气分级作用回收聚羟基链烷酸酯的方法
HU9603303D0 (en) * 1994-06-01 1997-01-28 Procter & Gamble Process for recovering polyhydroxyalkanoates using centrifugal fractionation
GB9414506D0 (en) * 1994-07-18 1994-09-07 Zeneca Ltd Improved production of polyhydroxyalkanoate
US6127606A (en) * 1995-02-08 2000-10-03 University Of Warwick Method of using transactivation proteins to control expression in transgenic plants
GB9502456D0 (en) * 1995-02-08 1995-03-29 Univ Warwick Control of genes in transgenic plants
US6083729A (en) * 1995-10-26 2000-07-04 Metabolix, Inc. Methods for isolating polyhydroxyalkanoates from plants
US5849894A (en) * 1995-11-29 1998-12-15 Monsanto Company Rhodospirillum rubrum poly-β-hydroxyalkanoate synthase
WO1997022711A1 (en) 1995-12-19 1997-06-26 Regents Of The University Of Minnesota Metabolic engineering of polyhydroxyalkanoate monomer synthases
US6143947A (en) * 1996-01-29 2000-11-07 The Procter & Gamble Company Fibers, nonwoven fabrics and absorbent articles comprising a biodegradable polyhydroxyalkanoate comprising 3-hydroxybutyrate and 3-hydroxyhexanoate
US5958745A (en) * 1996-03-13 1999-09-28 Monsanto Company Methods of optimizing substrate pools and biosynthesis of poly-β-hydroxybutyrate-co-poly-β-hydroxyvalerate in bacteria and plants
US6091002A (en) 1996-03-13 2000-07-18 Monsanto Company Polyhydroxyalkanoates of narrow molecular weight distribution prepared in transgenic plants
US5959179A (en) * 1996-03-13 1999-09-28 Monsanto Company Method for transforming soybeans
US6946588B2 (en) 1996-03-13 2005-09-20 Monsanto Technology Llc Nucleic acid encoding a modified threonine deaminase and methods of use
US5750848A (en) * 1996-08-13 1998-05-12 Monsanto Company DNA sequence useful for the production of polyhydroxyalkanoates
WO1999000505A1 (en) 1997-06-30 1999-01-07 The Curators Of The University Of Missouri Use of dna encoding plastid pyruvate dehydrogenase and branched chain oxoacid dehydrogenase components to enhance polyhydroxyalkanoate biosynthesis in plants
ATE328035T1 (de) 1997-07-25 2006-06-15 Metabolix Inc Pha-zusammensetzungen und deren verwendung zur herstellung von pha-filmen
AU725516B2 (en) * 1997-09-19 2000-10-12 Metabolix, Inc. Biological systems for manufacture of polyhydroxyalkanoate polymers containing 4-hydroxyacids
AU5907198A (en) * 1998-01-05 1999-07-26 Monsanto Company Biosynthesis of medium chain length polyhydroxyalkanoates
CA2317314C (en) 1998-01-07 2003-12-30 Metabolix, Inc. Animal nutrition compositions
JP3524495B2 (ja) * 1998-01-19 2004-05-10 エルジ ケミカル リミテッド アルカリゲネスラタス由来のポリヒドロキシアルカノエート生合成関連遺伝子
US6586658B1 (en) 1998-03-06 2003-07-01 Metabolix, Inc. Modification of fatty acid metabolism in plants
JP2002510747A (ja) 1998-04-08 2002-04-09 メタボリックス，インコーポレイテッド バイオポリマーの分離および精製のための方法
US6323010B1 (en) * 1998-05-22 2001-11-27 Metabolix, Inc. Polyhydroxyalkanoate biopolymer compositions
EP1100928B1 (de) * 1998-07-30 2006-02-01 Metabolix, Inc. Bifunktionelle enzyme zur biopolymerherstellung
MXPA01001111A (es) 1998-08-04 2002-04-24 Metabolix Inc Produccion de polihidroxialcanoato a partir de polioles.
US6174990B1 (en) 1998-12-21 2001-01-16 The Procter & Gamble Company Films comprising biodegradable PHA copolymers
US6077931A (en) * 1998-12-21 2000-06-20 The Procter & Gamble Company Biodegradable PHA copolymers
US6160199A (en) * 1998-12-21 2000-12-12 The Procter & Gamble Company Absorbent articles comprising biodegradable PHA copolymers
US6835820B2 (en) 1999-01-07 2004-12-28 The University Of Massachusetts Polyhydroxyalkanoate biosynthesis associated proteins and coding region in bacillus megaterium
EP1141317A1 (de) * 1999-01-07 2001-10-10 University of Massachusetts Polyhydroxyalkansäureesterbiosynthese assoziierte proteine und kodierende regionen in i(bacillus megaterium)
WO2000052183A1 (en) * 1999-03-05 2000-09-08 Monsanto Technology Llc Multigene expression vectors for the biosynthesis of products via multienzyme biological pathways
ES2243235T3 (es) 1999-03-15 2005-12-01 Universite Laval Metodo para la produccion de polihidroxialcanoatos en organismos recombinantes.
US6451564B1 (en) 1999-07-02 2002-09-17 Massachusetts Institute Of Technology Methods for producing L-isoleucine
EP1076095B1 (de) * 1999-08-09 2008-09-03 Riken Verfahren zur Transformierung von Pflanzen, transformierte Pflanzen und Verfahren zur Herstellung von Polyestern
US7700074B2 (en) * 2002-02-07 2010-04-20 Pettegrew Jay W Method and system for diagnosis of neuropsychiatric disorders including chronic alcoholism
US7407778B2 (en) 2002-02-07 2008-08-05 Pettegrew Jay W Compounds, compositions and methods for treating neuropsychiatric disorders
CN1795198B (zh) * 2003-05-29 2011-08-17 杰伊·W·佩特格尤 对神经精神疾病进行医学成像所用的甘油磷酸胆碱及其衍生物
US20060257842A1 (en) * 2003-05-29 2006-11-16 Pettegrew Jay W Cryopreservation media and molecules
US7666636B2 (en) * 2006-03-22 2010-02-23 National Research Council Of Canada Process for producing poly-β-hydroxybutyrate
JP5500823B2 (ja) 2006-09-01 2014-05-21 株式会社カネカ 熱可塑性エラストマー組成物
EP3214179B1 (de) 2007-03-16 2021-03-03 Genomatica, Inc. Zusammensetzungen und verfahren für die biosynthese von 1,4-butandiol und dessen vorläufern
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
EP3514242A3 (de) 2008-09-10 2019-08-28 Genomatica, Inc. Mikroorganismen zur herstellung von 1,4-butandiol
EP3199511B1 (de) * 2009-06-04 2020-01-29 Genomatica, Inc. Verfahren zur trennung von komponenten einer fermentierungsbrühe
WO2010141920A2 (en) 2009-06-04 2010-12-09 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol and related methods
CN105441374A (zh) * 2009-10-13 2016-03-30 基因组股份公司 生产1,4-丁二醇、4-羟基丁醛、4-羟基丁酰-coa、腐胺和相关化合物的微生物及其相关方法
US8530210B2 (en) 2009-11-25 2013-09-10 Genomatica, Inc. Microorganisms and methods for the coproduction 1,4-butanediol and gamma-butyrolactone
CA2788596A1 (en) 2010-02-11 2011-08-18 Metabolix, Inc. Process for producing a monomer component from a genetically modified polyhydroxyalkanoate biomass
US8445244B2 (en) * 2010-02-23 2013-05-21 Genomatica, Inc. Methods for increasing product yields
US8048661B2 (en) * 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
US20130052682A1 (en) 2011-02-14 2013-02-28 Xyleco, Inc. Processing biomass
CN104685058B (zh) 2012-06-04 2020-07-07 基因组股份公司 制造4-羟基丁酸酯、1，4-丁二醇和相关化合物的微生物和方法
CA3080669A1 (en) 2017-10-27 2019-05-02 Xyleco, Inc. Processing biomass
CA3141340A1 (en) * 2019-06-10 2020-12-17 Yield10 Bioscience, Inc. Transgenic land plants that express a polyhydroxyalkanoate synthase seed specifically with cytosolic localization

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US4266855A (en) * 1979-09-24 1981-05-12 Quantor Corporation Quick change lens system
ATE93542T1 (de) * 1984-12-28 1993-09-15 Plant Genetic Systems Nv Rekombinante dna, die in pflanzliche zellen eingebracht werden kann.
US5229279A (en) 1987-06-29 1993-07-20 Massachusetts Institute Of Technology Method for producing novel polyester biopolymers
US5250430A (en) 1987-06-29 1993-10-05 Massachusetts Institute Of Technology Polyhydroxyalkanoate polymerase
US5245023A (en) * 1987-06-29 1993-09-14 Massachusetts Institute Of Technology Method for producing novel polyester biopolymers
JPH05500751A (ja) * 1989-07-10 1993-02-18 マサチューセッツ インスティテュート オブ テクノロジー 新規なポリエステルバイオポリマー
GB9108756D0 (en) 1991-04-24 1991-06-12 Ici Plc Production of polyalkanoate in plants
GB9115245D0 (en) * 1991-07-16 1991-08-28 Ici Plc Production of polyalkanoate
ATE295891T1 (de) 1991-07-19 2005-06-15 Univ Michigan State Transgene pflanzen die polyhydroxyalkanoate produzieren
GB9223332D0 (en) 1992-11-06 1992-12-23 Ici Plc Production of polyhydroxyalkanoate in plants

Also Published As

Publication number Publication date
ATE435295T1 (de) 2009-07-15
GB9108756D0 (en) 1991-06-12
DE69233763D1 (de) 2009-08-13
CA2109221A1 (en) 1992-10-25
ATE221126T1 (de) 2002-08-15
EP1176207B1 (de) 2009-07-01
ES2182819T3 (es) 2003-03-16
EP0589898B1 (de) 2002-07-24
EP0589898A1 (de) 1994-04-06
EP1176207A3 (de) 2003-01-08
CA2109221C (en) 2007-03-06
DE69232694D1 (de) 2002-08-29
US6175061B1 (en) 2001-01-16
US5502273A (en) 1996-03-26
AU1579792A (en) 1992-12-21
WO1992019747A1 (en) 1992-11-12
DE69232694T2 (de) 2003-03-06
JPH06510422A (ja) 1994-11-24
ES2327897T3 (es) 2009-11-05
AU655816B2 (en) 1995-01-12
EP1176207A2 (de) 2002-01-30

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