ATE144287T1 - Verfahren zur optischen auftrennung von corey- lactondiolen - Google Patents

Verfahren zur optischen auftrennung von corey- lactondiolen

Info

Publication number
ATE144287T1
ATE144287T1 AT92102842T AT92102842T ATE144287T1 AT E144287 T1 ATE144287 T1 AT E144287T1 AT 92102842 T AT92102842 T AT 92102842T AT 92102842 T AT92102842 T AT 92102842T AT E144287 T1 ATE144287 T1 AT E144287T1
Authority
AT
Austria
Prior art keywords
corey lactone
lactone diols
optical separation
diols
corey
Prior art date
Application number
AT92102842T
Other languages
English (en)
Inventor
Seiichi Takano
Tsutomu Sugahara
Original Assignee
Nissan Chemical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Ind Ltd filed Critical Nissan Chemical Ind Ltd
Application granted granted Critical
Publication of ATE144287T1 publication Critical patent/ATE144287T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Glass Compositions (AREA)
AT92102842T 1991-02-27 1992-02-20 Verfahren zur optischen auftrennung von corey- lactondiolen ATE144287T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP03055839A JP3097145B2 (ja) 1991-02-27 1991-02-27 コーリーラクトンジオールの光学分割方法

Publications (1)

Publication Number Publication Date
ATE144287T1 true ATE144287T1 (de) 1996-11-15

Family

ID=13010168

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92102842T ATE144287T1 (de) 1991-02-27 1992-02-20 Verfahren zur optischen auftrennung von corey- lactondiolen

Country Status (6)

Country Link
US (1) US5219743A (de)
EP (1) EP0501310B1 (de)
JP (1) JP3097145B2 (de)
AT (1) ATE144287T1 (de)
DE (1) DE69214484T2 (de)
HU (1) HU217814B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9108376D0 (en) * 1991-04-19 1991-06-05 Enzymatix Ltd Cyclopentenes
CA2133959A1 (en) * 1992-04-21 1993-10-28 Chirotech Technology Limited Chiral cyclopentene derivatives and their preparation
US5840923A (en) * 1992-04-21 1998-11-24 Chiroscience Limited Chiral cyclopentene derivatives and their preparation
JPH07147994A (ja) * 1993-11-26 1995-06-13 Kureha Chem Ind Co Ltd １，２−ジオール誘導体の光学分割
PE20040991A1 (es) * 2002-08-12 2004-12-27 Lundbeck & Co As H Separacion de intermediarios para la preparacion de escitalopram
ITMI20040717A1 (it) * 2004-04-09 2004-07-09 Adorkem Technology Spa Procedimento chemo-enzimatico per la preparazione dell'escitalopram
EP1853719B1 (de) 2005-03-04 2009-09-02 Teva Pharmaceutical Industries Ltd Enzymatische umwandlung eines prostaglandin (bimatoprost)-zwischenproduktes
EP1736550A1 (de) * 2005-06-22 2006-12-27 Adorkem Technology SpA Chemoenzymatisches Verfahren zur Synthese von Escitalopram
HU226863B1 (en) * 2005-12-09 2009-12-28 Chinoin Gyogyszer Es Vegyeszet Process for separation of optical isomers of "corey-lactone" by liquid chromatography
RU2501793C2 (ru) * 2011-05-20 2013-12-20 Федеральное государственное бюджетное учреждение науки Институт органической химии Уфимского научного центра Российской академии наук (ИОХ УНЦ РАН) Способ получения энантиомерных производных лактона кори
CN102532079B (zh) * 2011-12-29 2014-09-17 北京洛斯顿精细化工有限公司 苯甲酰科里内酯的制备方法
CN105954447B (zh) * 2016-07-21 2018-12-28 吉林百纯化学科技有限公司 一种通过hplc分析分离苯甲酰科立内酯对映异构体的方法
CN112680497A (zh) * 2020-12-31 2021-04-20 南京赛信生物科技有限公司 生物酶拆分前列腺素类药物关键中间体（1S,5R）-Corey内酯的方法
CN113480506A (zh) * 2021-06-23 2021-10-08 四川大学 一种corey内酯二醇的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3818045A (en) * 1970-11-27 1974-06-18 Upjohn Co Certain bicyclic lactone diols
US3778450A (en) * 1971-03-23 1973-12-11 Upjohn Co Certain bicyclic lactones
US4304907A (en) * 1972-05-10 1981-12-08 The Upjohn Company Bicyclo lactone intermediates for prostaglandin analogs
US3943151A (en) * 1973-10-24 1976-03-09 Pfizer Inc. Prostaglandin intermediates
HU173711B (hu) * 1976-02-20 1979-07-28 Chinoin Gyogyszer Es Vegyeszet Sposob poluchenija biciklicheskikh proizvodnykh laktonov ispol'zuemykh intermediarnymi soedineijami v sinteze prostaglandinov
US4659671A (en) * 1983-07-01 1987-04-21 Massachusetts Institute Of Technology Enzymatic separation of racemic mixtures of hydroxy compounds
JPS61227797A (ja) * 1985-04-01 1986-10-09 Kanegafuchi Chem Ind Co Ltd 光学活性グリコ−ル類の製造方法
JPS63152339A (ja) * 1986-06-19 1988-06-24 Nissan Chem Ind Ltd 光学活性なビシクロカルボン酸とその誘導体
US5106750A (en) * 1988-08-30 1992-04-21 G. D. Searle & Co. Enantio- and regioselective synthesis of organic compounds using enol esters as irreversible transacylation reagents

Also Published As

Publication number Publication date
DE69214484D1 (de) 1996-11-21
EP0501310A1 (de) 1992-09-02
HU217814B (hu) 2000-04-28
HUT61337A (en) 1992-12-28
JPH04271797A (ja) 1992-09-28
DE69214484T2 (de) 1997-03-27
JP3097145B2 (ja) 2000-10-10
US5219743A (en) 1993-06-15
EP0501310B1 (de) 1996-10-16
HU9200638D0 (en) 1992-05-28

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