DK0566601T4 - Ekkokontrastmiddel - Google Patents

Ekkokontrastmiddel

Info

Publication number
DK0566601T4
DK0566601T4 DK92901804T DK92901804T DK0566601T4 DK 0566601 T4 DK0566601 T4 DK 0566601T4 DK 92901804 T DK92901804 T DK 92901804T DK 92901804 T DK92901804 T DK 92901804T DK 0566601 T4 DK0566601 T4 DK 0566601T4
Authority
DK
Denmark
Prior art keywords
contrast medium
echo contrast
echo
stabilisation
demonstration
Prior art date
Application number
DK92901804T
Other languages
Danish (da)
English (en)
Other versions
DK0566601T3 (da
Inventor
Klaus-Dieter Beller
Rudolf Linder
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6422745&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0566601(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Application granted granted Critical
Publication of DK0566601T3 publication Critical patent/DK0566601T3/da
Publication of DK0566601T4 publication Critical patent/DK0566601T4/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/227—Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Acoustics & Sound (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Graft Or Block Polymers (AREA)
  • Fish Paste Products (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Radiation-Therapy Devices (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
DK92901804T 1991-01-09 1992-01-04 Ekkokontrastmiddel DK0566601T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4100470A DE4100470A1 (de) 1991-01-09 1991-01-09 Echokontrastmittel
PCT/EP1992/000012 WO1992011873A1 (de) 1991-01-09 1992-01-04 Echokontrastmittel

Publications (2)

Publication Number Publication Date
DK0566601T3 DK0566601T3 (da) 1995-12-18
DK0566601T4 true DK0566601T4 (da) 2007-05-29

Family

ID=6422745

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92901804T DK0566601T4 (da) 1991-01-09 1992-01-04 Ekkokontrastmiddel

Country Status (25)

Country Link
US (1) US5599523A (es)
EP (2) EP0566601B2 (es)
JP (1) JP3290655B2 (es)
KR (1) KR100203221B1 (es)
AT (1) ATE126708T1 (es)
AU (1) AU652803B2 (es)
BG (1) BG61667B2 (es)
CA (1) CA2098915C (es)
CZ (1) CZ280939B6 (es)
DE (3) DE4100470A1 (es)
DK (1) DK0566601T4 (es)
ES (1) ES2079176T5 (es)
FI (1) FI119913B (es)
GR (1) GR3017925T3 (es)
HK (1) HK1006147A1 (es)
HU (1) HU220763B1 (es)
IE (1) IE70131B1 (es)
IL (1) IL100607A (es)
NZ (1) NZ241246A (es)
PL (1) PL167253B1 (es)
RU (1) RU2091079C1 (es)
SK (1) SK278776B6 (es)
UA (1) UA27121C2 (es)
WO (1) WO1992011873A1 (es)
ZA (1) ZA92118B (es)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
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US5922304A (en) * 1989-12-22 1999-07-13 Imarx Pharmaceutical Corp. Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents
US20040208826A1 (en) * 1990-04-02 2004-10-21 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US5445813A (en) 1992-11-02 1995-08-29 Bracco International B.V. Stable microbubble suspensions as enhancement agents for ultrasound echography
IN172208B (es) * 1990-04-02 1993-05-01 Sint Sa
US20010024638A1 (en) * 1992-11-02 2001-09-27 Michel Schneider Stable microbubble suspensions as enhancement agents for ultrasound echography and dry formulations thereof
US5578292A (en) 1991-11-20 1996-11-26 Bracco International B.V. Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
USRE39146E1 (en) 1990-04-02 2006-06-27 Bracco International B.V. Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
US7083778B2 (en) * 1991-05-03 2006-08-01 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US6989141B2 (en) * 1990-05-18 2006-01-24 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US6613306B1 (en) 1990-04-02 2003-09-02 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US20030194376A1 (en) * 1990-05-18 2003-10-16 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
AU636481B2 (en) * 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
GB9106686D0 (en) * 1991-03-28 1991-05-15 Hafslund Nycomed As Improvements in or relating to contrast agents
GB9107628D0 (en) * 1991-04-10 1991-05-29 Moonbrook Limited Preparation of diagnostic agents
US5993805A (en) * 1991-04-10 1999-11-30 Quadrant Healthcare (Uk) Limited Spray-dried microparticles and their use as therapeutic vehicles
MX9205298A (es) * 1991-09-17 1993-05-01 Steven Carl Quay Medios gaseosos de contraste de ultrasonido y metodo para seleccionar gases para usarse como medios de contraste de ultrasonido
US6875420B1 (en) 1991-09-17 2005-04-05 Amersham Health As Method of ultrasound imaging
DE605477T1 (de) * 1991-09-17 1998-09-24 Sonus Pharma Inc Gasförmige ultraschallkontrastmittel und verfahren zur auswahl von gasen für die verwendung als ultraschallkontrastmittel.
US6723303B1 (en) 1991-09-17 2004-04-20 Amersham Health, As Ultrasound contrast agents including protein stabilized microspheres of perfluoropropane, perfluorobutane or perfluoropentane
US5409688A (en) * 1991-09-17 1995-04-25 Sonus Pharmaceuticals, Inc. Gaseous ultrasound contrast media
GB9200388D0 (en) * 1992-01-09 1992-02-26 Nycomed As Improvements in or relating to contrast agents
IL104084A (en) 1992-01-24 1996-09-12 Bracco Int Bv Sustainable aqueous suspensions of pressure-resistant and gas-filled blisters, their preparation, and contrast agents containing them
US5464696A (en) * 1992-08-13 1995-11-07 Bracco International B.V. Particles for NMR imaging
GB9221329D0 (en) * 1992-10-10 1992-11-25 Delta Biotechnology Ltd Preparation of further diagnostic agents
IL108416A (en) 1993-01-25 1998-10-30 Sonus Pharma Inc Colloids with phase difference as contrast ultrasound agents
DE69427185T2 (de) * 1993-01-25 2001-12-06 Sonus Pharma Inc Phase-Stift Kolloide zur Verwendung als Ultraschallkontrastmittel
US5558855A (en) * 1993-01-25 1996-09-24 Sonus Pharmaceuticals Phase shift colloids as ultrasound contrast agents
US5716597A (en) * 1993-06-04 1998-02-10 Molecular Biosystems, Inc. Emulsions as contrast agents and method of use
US5798091A (en) 1993-07-30 1998-08-25 Alliance Pharmaceutical Corp. Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement
US5605673A (en) 1993-07-30 1997-02-25 Alliance Pharmaceutical Corp. Stabilized microbubble compositions for ultrasound
DE4328642A1 (de) * 1993-08-26 1995-03-02 Byk Gulden Lomberg Chem Fab Ultraschallkontrastmittel
GB9318288D0 (en) * 1993-09-03 1993-10-20 Nycomed Imaging As Improvements in or relating to contrast agents
CN1068229C (zh) * 1993-12-15 2001-07-11 勃勒柯研究有限公司 超声对比介质、含该介质的对比剂及方法
GB9417941D0 (en) * 1994-09-06 1994-10-26 Nycomed Imaging As Improvements in or relating to contrast agents
US5540909A (en) * 1994-09-28 1996-07-30 Alliance Pharmaceutical Corp. Harmonic ultrasound imaging with microbubbles
GB9423419D0 (en) * 1994-11-19 1995-01-11 Andaris Ltd Preparation of hollow microcapsules
WO2004073750A1 (en) 1995-06-07 2004-09-02 Harald Dugstad Improvements in or relating to contrast agents
US5804162A (en) 1995-06-07 1998-09-08 Alliance Pharmaceutical Corp. Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients
PL328406A1 (en) 1996-02-19 1999-01-18 Nycomed Imaging As Improved contrast media
CZ281298A3 (cs) * 1996-03-05 1999-01-13 Acusphere, Inc. Fluorované plyny v mikrokapslích jako zobrazující činidla pro ultrazvukové vyšetření
DE19626530A1 (de) * 1996-07-02 1998-01-15 Byk Gulden Lomberg Chem Fab MR-Kontrastmittelzubereitungen
MXPA99001053A (es) * 1996-08-02 2002-03-11 Nycomed Imaging As Mejoramientos en o que se relacionan con agentes de contraste.
US6017310A (en) * 1996-09-07 2000-01-25 Andaris Limited Use of hollow microcapsules
US6068600A (en) * 1996-12-06 2000-05-30 Quadrant Healthcare (Uk) Limited Use of hollow microcapsules
US6054118A (en) * 1997-01-22 2000-04-25 Nycomed Imaging As Contrast agents comprising two types of gas-containing microparticles
GB9701237D0 (en) * 1997-01-22 1997-03-12 Nycomed Imaging As Improvements in or relating to contrast agents
US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
DE19805012A1 (de) * 1998-02-07 1999-08-12 Thomas Gieselmann Kontrastmittel zur Verwendung als Diagnostikum bei bildgebenden Verfahren sowie seine Herstellung
GB9912356D0 (en) 1999-05-26 1999-07-28 Btg Int Ltd Generation of microfoam
US8512680B2 (en) 2001-08-08 2013-08-20 Btg International Ltd. Injectables in foam, new pharmaceutical applications
PT1694292E (pt) 2003-11-17 2009-10-26 Btg Int Ltd Espuma terapêutica
US8048439B2 (en) 2003-11-17 2011-11-01 Btg International Ltd. Therapeutic foam
US8012457B2 (en) 2004-06-04 2011-09-06 Acusphere, Inc. Ultrasound contrast agent dosage formulation
GB0509824D0 (en) 2005-05-13 2005-06-22 Btg Int Ltd Therapeutic foam
WO2007070827A2 (en) * 2005-12-15 2007-06-21 Bristol-Myers Squibb Pharma Company Contrast agents for myocardium perfusion imaging

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3141641A1 (de) * 1981-10-16 1983-04-28 Schering Ag, 1000 Berlin Und 4619 Bergkamen Ultraschall-kontrastmittel und dessen herstellung
US4900540A (en) * 1983-06-20 1990-02-13 Trustees Of The University Of Massachusetts Lipisomes containing gas for ultrasound detection
EP0318081B1 (en) * 1987-11-27 1991-07-24 Akzo N.V. Stabilization of antibodies
IN172208B (es) † 1990-04-02 1993-05-01 Sint Sa

Also Published As

Publication number Publication date
DE4290068D2 (de) 1993-10-07
EP0494615A1 (de) 1992-07-15
FI119913B (fi) 2009-05-15
AU652803B2 (en) 1994-09-08
HUT64239A (en) 1993-12-28
DE4100470A1 (de) 1992-07-16
WO1992011873A1 (de) 1992-07-23
ES2079176T3 (es) 1996-01-01
IL100607A0 (en) 1992-09-06
KR930703023A (ko) 1993-11-29
SK72993A3 (en) 1994-04-06
ATE126708T1 (de) 1995-09-15
UA27121C2 (uk) 2000-02-28
DE59203392D1 (de) 1995-09-28
DK0566601T3 (da) 1995-12-18
CZ280939B6 (cs) 1996-05-15
US5599523A (en) 1997-02-04
EP0566601B1 (de) 1995-08-23
AU1154792A (en) 1992-08-17
HK1006147A1 (en) 1999-02-12
CZ178093A3 (en) 1994-04-13
IE70131B1 (en) 1996-10-30
FI933137A (fi) 1993-07-08
PL167253B1 (pl) 1995-08-31
JP2000509363A (ja) 2000-07-25
CA2098915A1 (en) 1992-07-10
BG61667B2 (bg) 1998-02-27
KR100203221B1 (ko) 1999-06-15
GR3017925T3 (en) 1996-01-31
RU2091079C1 (ru) 1997-09-27
IL100607A (en) 1996-07-23
IE920038A1 (en) 1992-07-15
SK278776B6 (sk) 1998-02-04
JP3290655B2 (ja) 2002-06-10
ZA92118B (en) 1992-08-26
FI933137A0 (fi) 1993-07-08
NZ241246A (en) 1994-01-26
EP0566601B2 (de) 2007-02-21
HU220763B1 (hu) 2002-05-28
HU9301703D0 (en) 1993-09-28
CA2098915C (en) 2005-05-17
ES2079176T5 (es) 2007-10-16
EP0566601A1 (de) 1993-10-27

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