DK0550550T3 - 3,9-Diazabicyclo(3.3.1)nonan-7-yl-derivater, fremgangsmåde og intermediater til fremstilling af disse, og farmaceutiske præparater, hvori de er indeholdt - Google Patents

3,9-Diazabicyclo(3.3.1)nonan-7-yl-derivater, fremgangsmåde og intermediater til fremstilling af disse, og farmaceutiske præparater, hvori de er indeholdt

Info

Publication number
DK0550550T3
DK0550550T3 DK91916973T DK91916973T DK0550550T3 DK 0550550 T3 DK0550550 T3 DK 0550550T3 DK 91916973 T DK91916973 T DK 91916973T DK 91916973 T DK91916973 T DK 91916973T DK 0550550 T3 DK0550550 T3 DK 0550550T3
Authority
DK
Denmark
Prior art keywords
alkyl
phenyl
nonan
diazabicyclo
intermediates
Prior art date
Application number
DK91916973T
Other languages
Danish (da)
English (en)
Inventor
Julian Anthony C Oglax Gregory
F D King
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Application granted granted Critical
Publication of DK0550550T3 publication Critical patent/DK0550550T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK91916973T 1990-09-26 1991-09-23 3,9-Diazabicyclo(3.3.1)nonan-7-yl-derivater, fremgangsmåde og intermediater til fremstilling af disse, og farmaceutiske præparater, hvori de er indeholdt DK0550550T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909020927A GB9020927D0 (en) 1990-09-26 1990-09-26 Pharmaceuticals
PCT/GB1991/001629 WO1992005174A1 (en) 1990-09-26 1991-09-23 3,9-diazabicyclo (3.3.1) nonan-7-yl derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
DK0550550T3 true DK0550550T3 (da) 2003-09-08

Family

ID=10682769

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91916973T DK0550550T3 (da) 1990-09-26 1991-09-23 3,9-Diazabicyclo(3.3.1)nonan-7-yl-derivater, fremgangsmåde og intermediater til fremstilling af disse, og farmaceutiske præparater, hvori de er indeholdt

Country Status (18)

Country Link
EP (1) EP0550550B1 (https=)
JP (1) JP2831464B2 (https=)
KR (1) KR100200438B1 (https=)
AT (1) ATE245157T1 (https=)
AU (1) AU652187B2 (https=)
CA (1) CA2092431C (https=)
CY (1) CY2387B1 (https=)
DE (1) DE69133295T2 (https=)
DK (1) DK0550550T3 (https=)
ES (1) ES2203609T3 (https=)
GB (1) GB9020927D0 (https=)
IE (1) IE913352A1 (https=)
MX (1) MX9101236A (https=)
NZ (1) NZ239915A (https=)
PT (1) PT99028B (https=)
TW (1) TW240227B (https=)
WO (1) WO1992005174A1 (https=)
ZA (1) ZA917606B (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9121170D0 (en) * 1991-10-05 1991-11-20 Smithkline Beecham Plc Pharmaceuticals
US5344831A (en) * 1992-01-31 1994-09-06 Nisshin Flour Milling Co., Ltd. Diazabicyclo derivatives
GB9214184D0 (en) * 1992-07-03 1992-08-12 Smithkline Beecham Plc Pharmaceuticals
US5514690A (en) * 1992-11-17 1996-05-07 E. R. Squibb & Sons, Inc. Aminocarbonyl (thiocarbonyl) and cyanoguanidine derivatives of quinoline and indoline
US5869478A (en) * 1995-06-07 1999-02-09 Bristol-Myers Squibb Company Sulfonamido substituted benzopyran derivatives
US5629429A (en) * 1995-06-07 1997-05-13 Bristol-Myers Squibb Company Process for preparing 4-arylamino-benzopyran and related compounds
US5612370A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phenylglycine and phenylalaninen amido benzopyran derivatives
US5612323A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phosphinic ester substituted benzopyran derivatives
GB9721139D0 (en) 1997-10-07 1997-12-03 Glaxo Group Ltd Medicaments
HRP20041132A2 (en) 2002-04-29 2006-07-31 Actelion Pharmaceuticals Ltd. 7-aryl-3, 9-diazabicyclo (3.3.1) non-6-ene derivatives and their use as renin inhibitors in the treatment of hypertension, cardiovascular or renal diseases
EP1678176A1 (en) * 2003-10-13 2006-07-12 Actelion Pharmaceuticals Ltd. Diazabicyclononene derivatives and their use as renin inhibitors
US7737163B2 (en) 2004-06-15 2010-06-15 Pfizer Inc. Benzimidazolone carboxylic acid derivatives
WO2005123718A2 (en) 2004-06-15 2005-12-29 Pfizer Japan Inc. Benzimidazolone carboxylic acid derivatives
AP2007004067A0 (en) 2005-02-22 2007-08-31 Pfizer Oxyindole derivatives as 5HT4 receptor agonists
US8129538B1 (en) 2007-03-28 2012-03-06 Takeda Pharmaceutical Company Limited Renin inhibitors
GB201511382D0 (en) 2015-06-29 2015-08-12 Imp Innovations Ltd Novel compounds and their use in therapy
JP2025530213A (ja) 2022-09-09 2025-09-11 ミリックス ファーマ リミテッド Nmt阻害剤を含む抗体薬物コンジュゲート及びその使用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3687080T2 (de) * 1985-04-27 1993-03-25 Beecham Group Plc Azabicyclononyl-indazol-carboxamid mit 5-ht-antagonistischer wirkung.
HU895334D0 (en) * 1986-07-30 1990-01-28 Sandoz Ag Process for the preparation of nasal pharmaceutical compositions
US4920227A (en) * 1988-11-29 1990-04-24 Rorer Pharmaceutical Corp. Benzobicyclic carboxamide 5-HT3 antagonists
US4920219A (en) * 1988-11-29 1990-04-24 Rorer Pharmaceutical Corp. Substituted saturated and unsaturated indole quinoline and benzazepine carboxamides and their use as pharmacological agents

Also Published As

Publication number Publication date
DE69133295T2 (de) 2004-03-18
ES2203609T3 (es) 2004-04-16
JP2831464B2 (ja) 1998-12-02
IE913352A1 (en) 1992-04-08
CA2092431A1 (en) 1992-03-27
EP0550550B1 (en) 2003-07-16
AU652187B2 (en) 1994-08-18
AU8624491A (en) 1992-04-15
CY2387B1 (en) 2004-09-10
HK1012356A1 (en) 1999-07-30
MX9101236A (es) 1992-05-04
ATE245157T1 (de) 2003-08-15
WO1992005174A1 (en) 1992-04-02
NZ239915A (en) 1993-11-25
PT99028B (pt) 1999-02-26
JPH06501256A (ja) 1994-02-10
GB9020927D0 (en) 1990-11-07
TW240227B (https=) 1995-02-11
EP0550550A1 (en) 1993-07-14
KR100200438B1 (ko) 1999-06-15
PT99028A (pt) 1993-10-29
CA2092431C (en) 2002-12-10
KR930702345A (ko) 1993-09-08
DE69133295D1 (de) 2003-08-21
ZA917606B (en) 1992-09-30

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