DK0533845T3 - Anvendelse af 5,10,15,20-tetrakis(r-carboxyphenyl)porphin til detektion og behandling af lungecancer - Google Patents

Anvendelse af 5,10,15,20-tetrakis(r-carboxyphenyl)porphin til detektion og behandling af lungecancer

Info

Publication number
DK0533845T3
DK0533845T3 DK91913465T DK91913465T DK0533845T3 DK 0533845 T3 DK0533845 T3 DK 0533845T3 DK 91913465 T DK91913465 T DK 91913465T DK 91913465 T DK91913465 T DK 91913465T DK 0533845 T3 DK0533845 T3 DK 0533845T3
Authority
DK
Denmark
Prior art keywords
porphine
carboxyphenyl
tetrakis
treatment
radiotracer
Prior art date
Application number
DK91913465T
Other languages
Danish (da)
English (en)
Inventor
Dean A Cole
David C Moody Iii
L Edward Ellinwood
M Gerard Klein
Original Assignee
Sisters Of Charity Of Leavenwo
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sisters Of Charity Of Leavenwo, Univ California filed Critical Sisters Of Charity Of Leavenwo
Application granted granted Critical
Publication of DK0533845T3 publication Critical patent/DK0533845T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0485—Porphyrins, texaphyrins wherein the nitrogen atoms forming the central ring system complex the radioactive metal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0036—Porphyrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1206—Administration of radioactive gases, aerosols or breath tests
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57423—Specifically defined cancers of lung
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Optics & Photonics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Dispersion Chemistry (AREA)
  • Atmospheric Sciences (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK91913465T 1990-06-15 1991-06-17 Anvendelse af 5,10,15,20-tetrakis(r-carboxyphenyl)porphin til detektion og behandling af lungecancer DK0533845T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/539,999 US5162231A (en) 1989-10-25 1990-06-15 Method of using 5,10,15,20-tetrakis(carboxyphenyl)porphine for detecting cancers of the lung
PCT/US1991/004132 WO1991019977A1 (en) 1990-06-15 1991-06-17 USING 5,10,15,20-TETRAKIS(r-CARBOXYPHENYL)PORPHINE FOR DETECTING AND TREATING LUNG CANCER

Publications (1)

Publication Number Publication Date
DK0533845T3 true DK0533845T3 (da) 2004-02-16

Family

ID=24153544

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91913465T DK0533845T3 (da) 1990-06-15 1991-06-17 Anvendelse af 5,10,15,20-tetrakis(r-carboxyphenyl)porphin til detektion og behandling af lungecancer

Country Status (15)

Country Link
US (2) US5162231A (ru)
EP (1) EP0533845B1 (ru)
JP (1) JP3047468B2 (ru)
KR (1) KR0171393B1 (ru)
AT (1) ATE251750T1 (ru)
AU (2) AU8061491A (ru)
BR (1) BR9106563A (ru)
CA (1) CA2085464C (ru)
DE (1) DE69133325T2 (ru)
DK (1) DK0533845T3 (ru)
FI (1) FI925673A (ru)
HU (1) HUT63499A (ru)
NO (1) NO924820L (ru)
RU (1) RU2114430C1 (ru)
WO (2) WO1991019978A1 (ru)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622685A (en) * 1990-05-30 1997-04-22 Deutches Krebsforchunszentrum Stiftung Des Offentlichen Rechts Polyether-substituted porphyrin anti-tumor agents
US5252698A (en) * 1992-10-09 1993-10-12 Sri International Metal ion porphyrin-containing poly(azine)
US5464741A (en) * 1993-10-08 1995-11-07 Henwell, Inc. Palladium (II) octaethylporphine alpha-isothiocyanate as a phosphorescent label for immunoassays
US6490330B1 (en) * 1994-04-12 2002-12-03 The Regents Of The University Of California Production of high specific activity copper -67
US5716958A (en) * 1994-10-27 1998-02-10 Tobishi Pharmaceutical Co., Ltd. Amino acid derivative having anti-CCK activity
US5756726A (en) * 1995-06-02 1998-05-26 Pharmacyclics, Inc. Methods of producing singlet oxygen using compounds having improved functionalization
AU737650B2 (en) 1997-11-03 2001-08-23 Duke University Substituted porphyrins
US6703050B1 (en) * 1998-09-04 2004-03-09 The Regents Of The University Of Michigan Methods and compositions for the prevention or treatment of cancer
ATE552260T1 (de) 1999-01-25 2012-04-15 Nat Jewish Health Substituierte porphyrine und deren therapeutische verwendung
US6984498B2 (en) * 1999-12-27 2006-01-10 Adair Edwin L Method of cancer screening primarily utilizing non-invasive cell collection, fluorescence detection techniques, and radio tracing detection techniques
US6190877B1 (en) * 1999-12-27 2001-02-20 Edwin L. Adair Method of cancer screening primarily utilizing non-invasive cell collection and fluorescence detection techniques
US6750037B2 (en) * 1999-12-27 2004-06-15 Edwin L. Adair Method of cancer screening primarily utilizing non-invasive cell collection, fluorescence detection techniques, and radio tracing detection techniques
US6575888B2 (en) * 2000-01-25 2003-06-10 Biosurface Engineering Technologies, Inc. Bioabsorbable brachytherapy device
KR100390771B1 (ko) * 2000-08-31 2003-07-10 한국화학연구원 광역학 치료(ｐｄｔ)용 광민감성 물질로 유용한 포르피린유도체
DK1364044T3 (da) 2000-11-17 2012-05-07 Biomoda Inc Sammensætninger og fremgangsmåder til påvisning af præcancerøse tilstande i celle- og vævsprøver under anvendelse af 5,10,15,20-tetrakis(carboxyphenyl)porphin
AU2002248366B2 (en) 2001-01-19 2006-10-26 Aeolus Sciences, Inc. Cancer therapy
AU2002312194B8 (en) 2001-06-01 2008-05-15 Aeolus Sciences, Inc. Oxidant scavengers for treatment of diabetes or use in transplantation or induction of immune tolerance
US6566517B2 (en) 2001-06-06 2003-05-20 Brookhaven Science Associates, Llc Metalloporphyrins and their uses as imageable tumor-targeting agents for radiation therapy
EP1487983A4 (en) * 2002-03-01 2007-08-15 Sloan Kettering Inst Cancer PREVENTING THE REPEAT AND METASTASIS OF CANCER
CA2488500A1 (en) 2002-06-07 2003-12-18 Duke University Substituted porphyrins
ATE336266T1 (de) * 2002-06-21 2006-09-15 Adair Edwin Lloyd Anwendung von metalloporphyrinen zur behandlung von arteriosklerose
JP2005538093A (ja) 2002-07-23 2005-12-15 ザ リージェンツ オブ ザ ユニバーシティー オブ ミシガン 抗血管形成療法のための、テトラポリアンモニウムテトラチオモリブデートおよび関連化合物
US20070149496A1 (en) * 2003-10-31 2007-06-28 Jack Tuszynski Water-soluble compound
US6989443B2 (en) * 2004-06-28 2006-01-24 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
US6995260B2 (en) * 2004-05-20 2006-02-07 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
US20060094682A1 (en) * 2004-10-29 2006-05-04 Odyssey Thera, Inc. Kinase inhibitors for the treatment of diabetes and obesity
CA2651994C (en) * 2006-05-17 2016-04-19 Koninklijke Philips Electronics N.V. Retrospective sorting of 4d ct into breathing phases based on geometric analysis of imaging fiducials
US9957293B2 (en) * 2006-08-23 2018-05-01 Yeda Research And Development Company Ltd. Conjugates of RGD peptides and porphyrin or (bacterio)chlorophyll photosynthesizers and their uses
US8287839B2 (en) * 2006-12-04 2012-10-16 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
US8444953B2 (en) * 2007-03-22 2013-05-21 Brookhaven Science Associates, Llc Symmetric and asymmetric halogen-containing metallocarboranylporphyrins and uses thereof
US20080279781A1 (en) * 2007-05-10 2008-11-13 Brookhaven Science Associates, Llc Glycosylated Carboranylporphyrins and Uses Thereof
RU2506083C2 (ru) 2008-05-23 2014-02-10 Нэшнл Джуиш Хелт Способ лечения поражений, ассоциированных с воздействием алкилирующих веществ
ES2651068T3 (es) * 2009-07-17 2018-01-24 Bioaffinity Technologies, Inc. Sistema y procedimiento de análisis de muestras marcadas con 5,10,15,20 tetraquis(4 carboxifenil)porfirina (TCPP)
MX2018015916A (es) 2016-06-16 2019-03-28 Oncoselect Therapeutics Llc Compuestos de porfirina y composiciones útiles para el tratamiento de cáncer.
CN107589189B (zh) * 2017-09-06 2018-07-10 中国农业科学院饲料研究所 一种氟甲喹的手性对映体的检测方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4930516B1 (en) * 1985-11-13 1998-08-04 Laser Diagnostic Instr Inc Method for detecting cancerous tissue using visible native luminescence
US4783529A (en) * 1985-12-03 1988-11-08 Research Corporation Technologies Rapid synthesis of radiolabeled porphyrin complexes for medical application
US4857300A (en) * 1987-07-27 1989-08-15 Cytocorp, Inc. Cytological and histological fixative formulation and methods for using same

Also Published As

Publication number Publication date
AU8061491A (en) 1992-01-07
AU8190691A (en) 1992-01-07
RU2114430C1 (ru) 1998-06-27
EP0533845B1 (en) 2003-10-08
CA2085464A1 (en) 1991-12-16
DE69133325T2 (de) 2004-07-29
CA2085464C (en) 2002-12-17
BR9106563A (pt) 1993-06-22
EP0533845A4 (en) 1993-11-18
NO924820D0 (no) 1992-12-14
ATE251750T1 (de) 2003-10-15
EP0533845A1 (en) 1993-03-31
WO1991019977A1 (en) 1991-12-26
HU9203923D0 (en) 1993-03-29
JPH06500164A (ja) 1994-01-06
KR0171393B1 (ko) 1999-05-15
WO1991019978A1 (en) 1991-12-26
FI925673A0 (fi) 1992-12-14
US5162231A (en) 1992-11-10
FI925673A (fi) 1992-12-14
NO924820L (no) 1993-02-12
HUT63499A (en) 1993-08-30
AU670743B2 (en) 1996-08-01
DE69133325D1 (de) 2003-11-13
US5391547A (en) 1995-02-21
JP3047468B2 (ja) 2000-05-29

Similar Documents

Publication Publication Date Title
DK0533845T3 (da) Anvendelse af 5,10,15,20-tetrakis(r-carboxyphenyl)porphin til detektion og behandling af lungecancer
RU92016479A (ru) Применение 5,10,15,20-тетракис (4-карбоксифенил) порфина для обнаружения и лечения рака легких
Spiess et al. Bone cancers induced by 224Ra (Th X) in children and adults
Hambright et al. The distribution of various water soluble radioactive metalloporphyrins in tumor bearing mice
DeRiemer et al. BLEDTA: tumor localization by a bleomycin analog containing a metal-chelating group
Carpenter et al. Cerenkov luminescence endoscopy: improved molecular sensitivity with β−-emitting radiotracers
ATE60134T1 (de) System zur kohlenanalyse und gammastrahlendetektor.
NL7600104A (nl) Dragermateriaal voor plaatsbepaling met radio-ak- tieve isotopen in medisch onderzoek en werkwijze voor de bereiding daarvan.
Celentano et al. Preliminary tests of a prototype system for optical and radionuclide imaging in small animals
de Lima Radioisotopes in medicine
Lawrence Artificial radio-activity and neutron rays in biology and medicine
Moore Porphyrin Localisation and Treatment of Tumors
Cameron et al. A final summary of measurements of cosmogenic AI26 in stone meteorites
Son Radiation carcinogenesis
Liukkonen et al. Levels of 82Kr from the decay of 35 h 82Br
Parsa et al. Decay scheme of 2.71 h 92Sr
SE7908576L (sv) Apparat for legesbestemning av ett omrade i menniskokroppen med upptag av ett radioaktivt emne, serskilt av en ventrombos med upptag av 125 i
Cole et al. Method of using 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine for detecting cancers of the lung
MacDonald et al. Short term tissue distribution of several radionuclides useful in bone scanning.
Pai et al. F-18-FDG whole body scan using gamma camera equipped with ultra high energy collimator in cancer patients: comparison with FDG coincidence PET
Gottschalk Semiannual Report to THE ATOMIC ENERGY COMMISSION. MARCH 1968
Fujiwara et al. Triple-labeled Whole-body Autoradiography of Tumor Bearing Rat using 18F-FDG, 67Ga-Citrate and 75Se-Selenomethionine
Yang et al. “Clear Plate” Technique for Localization and Orientation in Rectilinear Scanning
Dennis The Assessment of Radioactive Contamination in Man 1984
IN652 MANILA PHILIPPINES^