DK0528841T3 - Fremgangsmåde til fremstilling af pyridoxyleret hæmoglobin - Google Patents

Fremgangsmåde til fremstilling af pyridoxyleret hæmoglobin

Info

Publication number
DK0528841T3
DK0528841T3 DK91908403T DK91908403T DK0528841T3 DK 0528841 T3 DK0528841 T3 DK 0528841T3 DK 91908403 T DK91908403 T DK 91908403T DK 91908403 T DK91908403 T DK 91908403T DK 0528841 T3 DK0528841 T3 DK 0528841T3
Authority
DK
Denmark
Prior art keywords
pct
hemoglobin
sec
date
preparation
Prior art date
Application number
DK91908403T
Other languages
Danish (da)
English (en)
Inventor
Rainer Eketorp
Robert Marschall
Original Assignee
Pharmacia & Upjohn Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Ab filed Critical Pharmacia & Upjohn Ab
Application granted granted Critical
Publication of DK0528841T3 publication Critical patent/DK0528841T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
DK91908403T 1990-04-18 1991-03-21 Fremgangsmåde til fremstilling af pyridoxyleret hæmoglobin DK0528841T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9001378A SE9001378D0 (sv) 1990-04-18 1990-04-18 A method for the preparation of pyridoxylated hemoglobin
PCT/SE1991/000221 WO1991016352A1 (en) 1990-04-18 1991-03-21 A method for the preparation of pyridoxylated hemoglobin

Publications (1)

Publication Number Publication Date
DK0528841T3 true DK0528841T3 (da) 1999-08-30

Family

ID=20379201

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91908403T DK0528841T3 (da) 1990-04-18 1991-03-21 Fremgangsmåde til fremstilling af pyridoxyleret hæmoglobin

Country Status (14)

Country Link
US (1) US5380824A (de)
EP (1) EP0528841B1 (de)
JP (1) JPH05506656A (de)
AT (1) ATE175425T1 (de)
AU (1) AU7741791A (de)
CA (1) CA2079006A1 (de)
DE (1) DE69130736T2 (de)
DK (1) DK0528841T3 (de)
ES (1) ES2127726T3 (de)
FI (1) FI104722B (de)
GR (1) GR3029872T3 (de)
NO (1) NO302949B1 (de)
SE (1) SE9001378D0 (de)
WO (1) WO1991016352A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5891735A (en) * 1995-09-15 1999-04-06 Duke University Medical Center Method for measuring nitric oxide in nitrosyl (FeII)-hemoglobin and S-nitrosohemoglobin
US6911427B1 (en) 1995-09-15 2005-06-28 Duke University No-modified hemoglobins and uses therefore
US6627738B2 (en) * 1995-09-15 2003-09-30 Duke University No-modified hemoglobins and uses therefor
US6498141B2 (en) * 1996-03-28 2002-12-24 Northfield Laboratories, Inc. Method and apparatus for preparing an acellular red blood cell substitute
US6894150B1 (en) * 1999-10-01 2005-05-17 Ross Walden Tye Non-pyrogenic, endotoxin-free, stroma-free tetrameric hemoglobin
DE10031740A1 (de) * 2000-06-29 2002-02-14 Sanguibio Tech Ag Künstliche Sauerstoffträger aus vernetztem modifizierten Human- oder Schweinehämoglobin mit verbesserten Eigenschaften, Verfahren zu ihrer technisch einfachen Herstellung aus gereinigtem Material in hohen Ausbeuten, sowie deren Verwendung
DE10031744A1 (de) 2000-06-29 2002-01-17 Sanguibio Tech Ag Mit Blutplasma verträgliche, vernetzte und mit Polyalkylenoxiden konjugierte Säugetierhämoglobine als künstliche medizinische Sauerstoffträger, ihre Herstellung und ihre Verwendung
CN100431602C (zh) * 2003-01-29 2008-11-12 北原实验室有限公司 具有低量四聚体的聚合血红蛋白溶液及制备方法
US20090004159A1 (en) * 2006-01-24 2009-01-01 The Board Of Trustees Of The University Of Illinoi Polymerized Hemoglobin Media and Its Use in Isolation and Transplantation of Islet Cells
WO2008021577A2 (en) * 2006-01-24 2008-02-21 The Board Of Trustees Of The University Of Illinois Polymerized hemoglobin media and its use in isolation and transplantation of islet cells
US7494974B2 (en) * 2006-10-24 2009-02-24 Ikor, Inc. Carboxymethylated cross-linked tetrameric hemoglobin
US7504377B2 (en) * 2006-10-23 2009-03-17 Ikor, Inc. Nitric oxide-blocked cross-linked tetrameric hemoglobin
CN105073801B (zh) * 2013-02-15 2017-03-08 和光纯药工业株式会社 着色组合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2449885C3 (de) * 1974-10-21 1980-04-30 Biotest-Serum-Institut Gmbh, 6000 Frankfurt Verfahren zur Herstellung von chemisch modifizierten haltbaren Hämoglobinpräparaten sowie das nach diesem Verfahren hergestellte modifizierte Hämoglobinpräparat
US4136093A (en) * 1976-04-23 1979-01-23 Biotest-Serum-Institut Gmbh Hemoglobin preparation with increased oxygen release
JPS5716815A (en) * 1980-07-02 1982-01-28 Ajinomoto Co Inc Oxygen transporting agent for artificial blood
US4529719A (en) * 1983-05-04 1985-07-16 Tye Ross W Modified crosslinked stroma-free tetrameric hemoglobin
US4831012A (en) * 1984-03-23 1989-05-16 Baxter International Inc. Purified hemoglobin solutions and method for making same
EP0179075B2 (de) * 1984-03-23 1997-10-15 BAXTER INTERNATIONAL INC. (a Delaware corporation) Hämoglobin mit reduziertem virusrisiko und dessen herstellung

Also Published As

Publication number Publication date
NO302949B1 (no) 1998-05-11
EP0528841A1 (de) 1993-03-03
GR3029872T3 (en) 1999-07-30
EP0528841B1 (de) 1999-01-07
SE9001378D0 (sv) 1990-04-18
NO923724L (no) 1992-09-24
ES2127726T3 (es) 1999-05-01
US5380824A (en) 1995-01-10
DE69130736T2 (de) 1999-07-22
FI104722B (fi) 2000-03-31
AU7741791A (en) 1991-11-11
CA2079006A1 (en) 1991-10-19
NO923724D0 (no) 1992-09-24
FI924710A (fi) 1992-10-16
WO1991016352A1 (en) 1991-10-31
FI924710A0 (fi) 1992-10-16
JPH05506656A (ja) 1993-09-30
DE69130736D1 (de) 1999-02-18
ATE175425T1 (de) 1999-01-15

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