ES2127726T3 - Un metodo para la preparacion de hemoglobina piridoxilada. - Google Patents
Un metodo para la preparacion de hemoglobina piridoxilada.Info
- Publication number
- ES2127726T3 ES2127726T3 ES91908403T ES91908403T ES2127726T3 ES 2127726 T3 ES2127726 T3 ES 2127726T3 ES 91908403 T ES91908403 T ES 91908403T ES 91908403 T ES91908403 T ES 91908403T ES 2127726 T3 ES2127726 T3 ES 2127726T3
- Authority
- ES
- Spain
- Prior art keywords
- hemoglobin
- preparation
- pyridoxylated hemoglobin
- hemogen
- agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
- C07K14/805—Haemoglobins; Myoglobins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
SE PRESENTA UN METODO PARA PREPARAR HEMOGLOBINA PIRIDOXILADA EN UN PROCESO DE UN SOLO PASO EN UN UNICO ENVASE A PARTIR DE GLOBULOS ROJOS O A PARTIR DE HEMOGLOBINA ESENCIALMENTE LIBRE DE ESTROMA MEDIANTE LA SUSPENSION DE LAS CELULAS O DE LA HEMOGLOBINA EN UN MEDIO ACUOSO, LA ADICION DE UN AGENTE DE REDUCCION QUIMICA Y UN AGENTE PIRIDOXILANTE, Y EL CALENTAMIENTO DE LA MEZCLA DE REACCION OBTENIDA HASTA UNA CIERTA TEMPERATURA DURANTE UN CIERTO TIEMPO, MIENTRAS SE MANTIENEN LAS CONDICIONES DE REDUCCION EN EL MEDIO DE REACCION.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9001378A SE9001378D0 (sv) | 1990-04-18 | 1990-04-18 | A method for the preparation of pyridoxylated hemoglobin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2127726T3 true ES2127726T3 (es) | 1999-05-01 |
Family
ID=20379201
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES91908403T Expired - Lifetime ES2127726T3 (es) | 1990-04-18 | 1991-03-21 | Un metodo para la preparacion de hemoglobina piridoxilada. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5380824A (es) |
| EP (1) | EP0528841B1 (es) |
| JP (1) | JPH05506656A (es) |
| AT (1) | ATE175425T1 (es) |
| AU (1) | AU7741791A (es) |
| CA (1) | CA2079006A1 (es) |
| DE (1) | DE69130736T2 (es) |
| DK (1) | DK0528841T3 (es) |
| ES (1) | ES2127726T3 (es) |
| FI (1) | FI104722B (es) |
| GR (1) | GR3029872T3 (es) |
| NO (1) | NO302949B1 (es) |
| SE (1) | SE9001378D0 (es) |
| WO (1) | WO1991016352A1 (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6911427B1 (en) | 1995-09-15 | 2005-06-28 | Duke University | No-modified hemoglobins and uses therefore |
| US5891735A (en) * | 1995-09-15 | 1999-04-06 | Duke University Medical Center | Method for measuring nitric oxide in nitrosyl (FeII)-hemoglobin and S-nitrosohemoglobin |
| US6627738B2 (en) | 1995-09-15 | 2003-09-30 | Duke University | No-modified hemoglobins and uses therefor |
| ATE241646T1 (de) * | 1996-03-28 | 2003-06-15 | Northfield Lab | Verfahren und vorrichtung zur herstellung eines zellfreien ersatzes roter blutzellen |
| US6894150B1 (en) * | 1999-10-01 | 2005-05-17 | Ross Walden Tye | Non-pyrogenic, endotoxin-free, stroma-free tetrameric hemoglobin |
| DE10031744A1 (de) | 2000-06-29 | 2002-01-17 | Sanguibio Tech Ag | Mit Blutplasma verträgliche, vernetzte und mit Polyalkylenoxiden konjugierte Säugetierhämoglobine als künstliche medizinische Sauerstoffträger, ihre Herstellung und ihre Verwendung |
| DE10031740A1 (de) * | 2000-06-29 | 2002-02-14 | Sanguibio Tech Ag | Künstliche Sauerstoffträger aus vernetztem modifizierten Human- oder Schweinehämoglobin mit verbesserten Eigenschaften, Verfahren zu ihrer technisch einfachen Herstellung aus gereinigtem Material in hohen Ausbeuten, sowie deren Verwendung |
| JP2006516994A (ja) * | 2003-01-29 | 2006-07-13 | ノースフィールド ラボラトリーズ、インコーポレイテッド | テトラマーの量を低下させた重合ヘモグロビン溶液及び調製するための方法 |
| WO2007087570A2 (en) * | 2006-01-24 | 2007-08-02 | Northfield Laboratories, Inc. | Polymerized hemoglobin media and its use in isolation and transplantation of islet cells |
| US20090004159A1 (en) * | 2006-01-24 | 2009-01-01 | The Board Of Trustees Of The University Of Illinoi | Polymerized Hemoglobin Media and Its Use in Isolation and Transplantation of Islet Cells |
| US7504377B2 (en) * | 2006-10-23 | 2009-03-17 | Ikor, Inc. | Nitric oxide-blocked cross-linked tetrameric hemoglobin |
| US7494974B2 (en) * | 2006-10-24 | 2009-02-24 | Ikor, Inc. | Carboxymethylated cross-linked tetrameric hemoglobin |
| WO2014126167A1 (ja) * | 2013-02-15 | 2014-08-21 | 和光純薬工業株式会社 | 着色組成物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2449885C3 (de) * | 1974-10-21 | 1980-04-30 | Biotest-Serum-Institut Gmbh, 6000 Frankfurt | Verfahren zur Herstellung von chemisch modifizierten haltbaren Hämoglobinpräparaten sowie das nach diesem Verfahren hergestellte modifizierte Hämoglobinpräparat |
| US4136093A (en) * | 1976-04-23 | 1979-01-23 | Biotest-Serum-Institut Gmbh | Hemoglobin preparation with increased oxygen release |
| JPS5716815A (en) * | 1980-07-02 | 1982-01-28 | Ajinomoto Co Inc | Oxygen transporting agent for artificial blood |
| US4529719A (en) * | 1983-05-04 | 1985-07-16 | Tye Ross W | Modified crosslinked stroma-free tetrameric hemoglobin |
| DE3587351T3 (de) * | 1984-03-23 | 1998-04-16 | Baxter Int | Hämoglobin mit reduziertem virusrisiko und dessen herstellung. |
| US4831012A (en) * | 1984-03-23 | 1989-05-16 | Baxter International Inc. | Purified hemoglobin solutions and method for making same |
-
1990
- 1990-04-18 SE SE9001378A patent/SE9001378D0/xx unknown
-
1991
- 1991-03-21 WO PCT/SE1991/000221 patent/WO1991016352A1/en not_active Ceased
- 1991-03-21 EP EP91908403A patent/EP0528841B1/en not_active Expired - Lifetime
- 1991-03-21 US US07/927,419 patent/US5380824A/en not_active Expired - Lifetime
- 1991-03-21 AT AT91908403T patent/ATE175425T1/de not_active IP Right Cessation
- 1991-03-21 JP JP91507958A patent/JPH05506656A/ja active Pending
- 1991-03-21 DE DE69130736T patent/DE69130736T2/de not_active Expired - Lifetime
- 1991-03-21 ES ES91908403T patent/ES2127726T3/es not_active Expired - Lifetime
- 1991-03-21 DK DK91908403T patent/DK0528841T3/da active
- 1991-03-21 CA CA002079006A patent/CA2079006A1/en not_active Abandoned
- 1991-03-21 AU AU77417/91A patent/AU7741791A/en not_active Abandoned
-
1992
- 1992-09-24 NO NO923724A patent/NO302949B1/no not_active IP Right Cessation
- 1992-10-16 FI FI924710A patent/FI104722B/fi active
-
1999
- 1999-04-05 GR GR990400961T patent/GR3029872T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69130736D1 (de) | 1999-02-18 |
| NO302949B1 (no) | 1998-05-11 |
| GR3029872T3 (en) | 1999-07-30 |
| DE69130736T2 (de) | 1999-07-22 |
| SE9001378D0 (sv) | 1990-04-18 |
| US5380824A (en) | 1995-01-10 |
| FI924710A0 (fi) | 1992-10-16 |
| EP0528841B1 (en) | 1999-01-07 |
| NO923724L (no) | 1992-09-24 |
| AU7741791A (en) | 1991-11-11 |
| JPH05506656A (ja) | 1993-09-30 |
| DK0528841T3 (da) | 1999-08-30 |
| NO923724D0 (no) | 1992-09-24 |
| ATE175425T1 (de) | 1999-01-15 |
| WO1991016352A1 (en) | 1991-10-31 |
| FI924710L (fi) | 1992-10-16 |
| FI104722B (fi) | 2000-03-31 |
| EP0528841A1 (en) | 1993-03-03 |
| CA2079006A1 (en) | 1991-10-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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