DK0513351T3 - 2-Nitroimidazolderivat, fremstilling deraf og strålingssensibilisator indeholdende samme som aktiv bestanddel - Google Patents

2-Nitroimidazolderivat, fremstilling deraf og strålingssensibilisator indeholdende samme som aktiv bestanddel

Info

Publication number
DK0513351T3
DK0513351T3 DK91902775.5T DK91902775T DK0513351T3 DK 0513351 T3 DK0513351 T3 DK 0513351T3 DK 91902775 T DK91902775 T DK 91902775T DK 0513351 T3 DK0513351 T3 DK 0513351T3
Authority
DK
Denmark
Prior art keywords
active ingredient
preparation
containing same
nitroimidazole derivative
radiation sensitizer
Prior art date
Application number
DK91902775.5T
Other languages
Danish (da)
English (en)
Inventor
Toshimitsu Suzuki
Masakazu Sakaguchi
Yoshiyuki Miyata
Akira Suzuki
Tomoyuki Mori
Original Assignee
Pola Chem Ind Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pola Chem Ind Inc filed Critical Pola Chem Ind Inc
Application granted granted Critical
Publication of DK0513351T3 publication Critical patent/DK0513351T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK91902775.5T 1990-01-26 1991-01-24 2-Nitroimidazolderivat, fremstilling deraf og strålingssensibilisator indeholdende samme som aktiv bestanddel DK0513351T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2016721A JP2626727B2 (ja) 1990-01-26 1990-01-26 ２―ニトロイミダゾール誘導体、その製造法及びこれを有効成分とする放射線増感剤

Publications (1)

Publication Number Publication Date
DK0513351T3 true DK0513351T3 (da) 1996-11-25

Family

ID=11924130

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91902775.5T DK0513351T3 (da) 1990-01-26 1991-01-24 2-Nitroimidazolderivat, fremstilling deraf og strålingssensibilisator indeholdende samme som aktiv bestanddel

Country Status (10)

Country Link
US (1) US5270330A (es)
EP (1) EP0513351B1 (es)
JP (1) JP2626727B2 (es)
KR (2) KR927003539A (es)
AT (1) ATE143950T1 (es)
CA (1) CA2074533C (es)
DE (1) DE69122605T2 (es)
DK (1) DK0513351T3 (es)
ES (1) ES2094218T3 (es)
WO (1) WO1991011440A1 (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994014778A1 (en) * 1992-12-18 1994-07-07 Pola Chemical Industries, Inc. Optically active 2-nitroimidazole derivative, process for producing the same, and intermediate for producing the same
US5700825A (en) * 1995-03-31 1997-12-23 Florida State University Radiosensitizing diamines and their pharmaceutical preparations
US6060604A (en) * 1995-03-31 2000-05-09 Florida State University Pharmaceutical compounds comprising polyamines substituted with electron-affinic groups
US6331286B1 (en) 1998-12-21 2001-12-18 Photogen, Inc. Methods for high energy phototherapeutics
US5929104A (en) * 1997-04-02 1999-07-27 Pola Chemical Industries, Inc. Method for inducing apoptosis of cancer cell
US8974363B2 (en) 1997-12-11 2015-03-10 Provectus Pharmatech, Inc. Topical medicaments and methods for photodynamic treatment of disease
US8557298B2 (en) 1998-08-06 2013-10-15 Provectus Pharmatech, Inc. Medicaments for chemotherapeutic treatment of disease
US20020001567A1 (en) * 1998-12-21 2002-01-03 Photogen, Inc. Intracorporeal medicaments for high energy phototherapeutic treatment of disease
US8470296B2 (en) * 1998-12-21 2013-06-25 Provectus Pharmatech, Inc. Intracorporeal medicaments for high energy phototherapeutic treatment of disease
US7384623B1 (en) 1998-12-21 2008-06-10 Provectus Pharmatech, Inc. High energy phototherapeutic agents
WO2004060346A2 (en) 2002-12-30 2004-07-22 Angiotech International Ag Drug delivery from rapid gelling polymer composition
EP1590440A4 (en) * 2003-02-03 2009-03-18 Palo Alto Inst Of Molecular Me CELL-KILLING MOLECULES AND METHODS FOR THEIR USE
ZA200507752B (en) * 2003-03-28 2007-01-31 Threshold Pharmaceuticals Inc Compositions and methods for treating cancer
WO2005086951A2 (en) * 2004-03-10 2005-09-22 Threshold Pharmaceuticals, Inc. Hypoxia-activated anti-cancer agents
KR100832167B1 (ko) * 2004-06-24 2008-05-23 토요 수이산 가부시키가이샤 방사선치료 증감제
WO2006078903A1 (en) * 2005-01-21 2006-07-27 Matthews Richard H Radiosensitizer formulations comprising nitrohistidine derivatives
WO2007002931A2 (en) 2005-06-29 2007-01-04 Threshold Pharmaceuticals, Inc. Phosphoramidate alkylator prodrugs
WO2008083101A1 (en) * 2006-12-26 2008-07-10 Threshold Pharmaceuticals, Inc. Phosphoramidate alkylator prodrugs for the treatment of cancer
EP2128140B1 (en) 2007-01-23 2012-03-14 Pola Pharma Inc. Method for producing 2-nitroimidazole derivative
DK2116241T3 (en) 2007-01-26 2016-06-06 Pola Pharma Inc pharmaceutical composition
WO2008152764A1 (ja) 2007-06-14 2008-12-18 Pola Pharma Inc. 医薬組成物
US20090118031A1 (en) * 2007-11-01 2009-05-07 Qualizza Gregory K Shaft Structure with Configurable Bending Profile
JP6082644B2 (ja) * 2013-03-22 2017-02-15 株式会社ポーラファルマ ドラニダゾール構成光学異性体の製造方法
JP6071715B2 (ja) * 2013-03-22 2017-02-01 株式会社ポーラファルマ ドラニダゾール構成光学異性体の製造方法
JP7353606B2 (ja) 2017-10-02 2023-10-02 慶應義塾 癌幹細胞インヒビター

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4462992A (en) * 1982-02-08 1984-07-31 Research Corporation Nitroimidazole radiosensitizers for hypoxic tumor cells and compositions thereof
JPS59139363A (ja) * 1983-01-31 1984-08-10 Kayaku:Kk ２−ニトロイミダゾ−ル誘導体およびその製造法
JPS6075430A (ja) * 1983-08-31 1985-04-27 Kayaku:Kk 放射線増感剤
JPH0819111B2 (ja) * 1987-10-22 1996-02-28 ポーラ化成工業株式会社 ２―ニトロイミダゾール誘導体及びこれを有効成分とする放射線増感剤
JP3291590B2 (ja) * 1992-08-26 2002-06-10 キヤノン株式会社 カラートナー、カラー現像剤及び画像形成方法

Also Published As

Publication number Publication date
DE69122605T2 (de) 1997-02-13
ATE143950T1 (de) 1996-10-15
JPH03223258A (ja) 1991-10-02
ES2094218T3 (es) 1997-01-16
US5270330A (en) 1993-12-14
CA2074533C (en) 2000-10-17
KR0145333B1 (en) 1998-07-15
JP2626727B2 (ja) 1997-07-02
DE69122605D1 (de) 1996-11-14
EP0513351A1 (en) 1992-11-19
WO1991011440A1 (fr) 1991-08-08
KR927003539A (ko) 1992-12-18
EP0513351B1 (en) 1996-10-09
EP0513351A4 (en) 1993-11-10
CA2074533A1 (en) 1991-07-27

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