MX9206157A - Derivados de imidazol y composiciones farmaceuticas que contienen a los mismos. - Google Patents

Derivados de imidazol y composiciones farmaceuticas que contienen a los mismos.

Info

Publication number
MX9206157A
MX9206157A MX9206157A MX9206157A MX9206157A MX 9206157 A MX9206157 A MX 9206157A MX 9206157 A MX9206157 A MX 9206157A MX 9206157 A MX9206157 A MX 9206157A MX 9206157 A MX9206157 A MX 9206157A
Authority
MX
Mexico
Prior art keywords
contain
pharmaceutical compositions
imidazole
derivatives
compounds
Prior art date
Application number
MX9206157A
Other languages
English (en)
Inventor
Hiroshi Kushida
Osamu Morita
Hiroyoshi Yamada
Kiyotaka Munesada
Kazuo Tsuzuki
Mineo Kunihara Joshiji Fujita
Keiko Koh
Mikio Taniguchi
Noriie Itoh
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of MX9206157A publication Critical patent/MX9206157A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La presente invención proporciona derivados de imidazol novedoso que tienen la fórmula química (I), estos compuestos son útiles para la prevención o el tratamiento de la hipertensión o fallas del corazón congestionadas, y que tienen buena actividad, acción rápida, en la inyección intravenosa, buena absorción oral, baja toxicidad, y acción prolongada. También se proporciona composiciones farmacéuticas, que contienen estos compuestos.
MX9206157A 1991-10-24 1992-10-26 Derivados de imidazol y composiciones farmaceuticas que contienen a los mismos. MX9206157A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP27753791 1991-10-24
JP32347491 1991-12-07
JP9519192 1992-04-15
JP4216809A JPH06107661A (ja) 1991-10-24 1992-08-14 イミダゾール誘導体およびこれを有効成分とする医薬組成物

Publications (1)

Publication Number Publication Date
MX9206157A true MX9206157A (es) 1994-05-31

Family

ID=27468309

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9206157A MX9206157A (es) 1991-10-24 1992-10-26 Derivados de imidazol y composiciones farmaceuticas que contienen a los mismos.

Country Status (11)

Country Link
EP (2) EP0540209A1 (es)
JP (2) JPH06107661A (es)
AT (1) ATE140458T1 (es)
AU (1) AU661346B2 (es)
CA (1) CA2118802A1 (es)
DE (1) DE69212331T2 (es)
DK (1) DK0609289T3 (es)
ES (1) ES2091489T3 (es)
GR (1) GR3021143T3 (es)
MX (1) MX9206157A (es)
WO (1) WO1993008193A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06271576A (ja) * 1993-03-19 1994-09-27 Upjohn Co:The イミダゾール誘導体の製法
US6005105A (en) * 1993-06-21 1999-12-21 Pharmacia & Upjohn Company Process for producing imidazole derivative
JPH0710879A (ja) * 1993-06-21 1995-01-13 Upjohn Co:The イミダゾール誘導体の製法
AUPN236595A0 (en) 1995-04-11 1995-05-11 Rescare Limited Monitoring of apneic arousals
SE9903028D0 (sv) * 1999-08-27 1999-08-27 Astra Ab New use
PL353199A1 (en) 1999-08-30 2003-11-03 Aventis Pharma Deutschland Gmbh Use of inhibitors of the renin-angiotensin system in the prevention of cardiovascular events
EP2170930B3 (en) 2007-06-04 2013-10-02 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
JP2011522828A (ja) 2008-06-04 2011-08-04 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
AU2009270833B2 (en) 2008-07-16 2015-02-19 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
WO2014151206A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
EP3004138B1 (en) 2013-06-05 2024-03-13 Bausch Health Ireland Limited Ultra-pure agonists of guanylate cyclase c, method of making and using same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4250180A (en) * 1979-07-16 1981-02-10 Ortho Pharmaceutical Corporation Method of treating arrhythmia
GB2128984B (en) * 1982-05-12 1985-05-22 Hoffmann La Roche Diaza-bicyclic compounds
DE3347290A1 (de) * 1983-12-28 1985-07-11 Dr. Karl Thomae Gmbh, 7950 Biberach Neue 2-phenyl-imidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel
IE64514B1 (en) * 1989-05-23 1995-08-09 Zeneca Ltd Azaindenes
IL96019A0 (en) * 1989-10-31 1991-07-18 Fujisawa Pharmaceutical Co Imidazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same

Also Published As

Publication number Publication date
ATE140458T1 (de) 1996-08-15
ES2091489T3 (es) 1996-11-01
DK0609289T3 (da) 1996-11-25
CA2118802A1 (en) 1993-04-29
JPH07500336A (ja) 1995-01-12
EP0540209A1 (en) 1993-05-05
GR3021143T3 (en) 1996-12-31
EP0609289A1 (en) 1994-08-10
WO1993008193A1 (en) 1993-04-29
AU661346B2 (en) 1995-07-20
EP0609289B1 (en) 1996-07-17
JPH06107661A (ja) 1994-04-19
DE69212331T2 (de) 1997-01-09
AU2759292A (en) 1993-05-21
DE69212331D1 (de) 1996-08-22

Similar Documents

Publication Publication Date Title
FI924397A (fi) Substituerade pyrimidiner
ES2175624T3 (es) Derivados de pirazolo(4,3-d)pirimidina y composiciones farmaceuticas que los contienen.
NO922147L (no) Heterocykliske derivater
DE69725978D1 (de) Chalcon-derivate und medikamente die diese enthalten
EA200100755A1 (ru) 4-оксо-1,4-дигидро-3-хинолинкарбоксамиды как антивирусные агенты
ES2091489T3 (es) Derivados de imidazol y composiciones farmaceuticas que los contienen.
DE69205327T2 (de) Harnstoffderivate, Verfahren zu ihrer Herstellung und diese enthaltende Medikamente.
DK0622361T3 (da) Heterocykliske forbindelser som bradykininantagonister
ATE260255T1 (de) 5-oxo-pyrrolidine-2-carbonsäure- hydroxamidderivate
ATE243697T1 (de) Substitutierte heterozyclische derivate als crf antagonisten
DK0928788T3 (da) Imidazolidin-4-on-derivater, der er nyttige som anticancer-midler
DE69108138T2 (de) Imidazopyridinderivate und ihre Verwendung.
PT976748E (pt) Derivados de pirrolidina com actividade inibidora de fosfolipase a2
DE69524246T2 (de) 1,2,3,4-Tetrahydroquinoxalindion Derivate und ihre Verwendung als Glutamat Rezeptor Antagonisten
DE69122418D1 (de) Arzneimittellösung enhaltend Derivate von FK506
DE69200160D1 (de) Angiotensin-II-Antagonisten.
WO1992019211A3 (en) Imidazobenzoquinones and composition for preventing or treating hypertension or congestive heart failure containing the same
DK0412940T3 (da) Hydantoin eller imidazolidintrionderivater til forebyggelse eller behandling af nyresvigt.
DE69202166T2 (de) Verwendung von Tetrahydrothienopyridinderivate als Angiogenese-Inhibitoren.
NO961236L (no) Pyrrolodiazin-derivater som stabilisatorer for klorholdige polymerisater
DK360388A (da) Laegemiddel til behandling af hjerteinsufficiens