ES2167463T3 - Componentes de un compuesto medicinal que comprenden derivados n-sustituidos de la o-toluidina y preparacion percutaneamente absorbible. - Google Patents

Componentes de un compuesto medicinal que comprenden derivados n-sustituidos de la o-toluidina y preparacion percutaneamente absorbible.

Info

Publication number
ES2167463T3
ES2167463T3 ES95933615T ES95933615T ES2167463T3 ES 2167463 T3 ES2167463 T3 ES 2167463T3 ES 95933615 T ES95933615 T ES 95933615T ES 95933615 T ES95933615 T ES 95933615T ES 2167463 T3 ES2167463 T3 ES 2167463T3
Authority
ES
Spain
Prior art keywords
toluidine
components
absorbable preparation
substituted derivatives
percutaneously absorbable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95933615T
Other languages
English (en)
Inventor
Munehiko Hirano
Mitsuru Kuribayashi
Mitsuhiko Kido
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hisamitsu Pharmaceutical Co Inc
Original Assignee
Hisamitsu Pharmaceutical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co Inc filed Critical Hisamitsu Pharmaceutical Co Inc
Application granted granted Critical
Publication of ES2167463T3 publication Critical patent/ES2167463T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

RESOLVENTE DE MEDICAMENTO Y SORBEFACIENTE DE MEDICAMENTO QUE INCLUYE CADA UNO AL MENOS UN DERIVADO N-SUSTITUTIVO-O-TOLUIDINA REPRESENTADO POR LA FORMULA GENERAL (I), Y UNA PREPARACION ABSORBIBLE PERCUTANEAMENTE QUE CONTIENE UN MEDICAMENTO Y EL RESOLVENTE O SORBEFACIENTE, DONDE R{SUB,1} REPRESENTA C{SUB,1}C{SUB,4} ALQUIL; Y R{SUB,2} REPRESENTA C{SUB,1}-C{SUB,8} ALQUIL.
ES95933615T 1994-10-05 1995-10-04 Componentes de un compuesto medicinal que comprenden derivados n-sustituidos de la o-toluidina y preparacion percutaneamente absorbible. Expired - Lifetime ES2167463T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP26829294 1994-10-05
JP19793895 1995-07-12

Publications (1)

Publication Number Publication Date
ES2167463T3 true ES2167463T3 (es) 2002-05-16

Family

ID=26510665

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95933615T Expired - Lifetime ES2167463T3 (es) 1994-10-05 1995-10-04 Componentes de un compuesto medicinal que comprenden derivados n-sustituidos de la o-toluidina y preparacion percutaneamente absorbible.

Country Status (9)

Country Link
US (1) US5891920A (es)
EP (1) EP0782861B1 (es)
JP (1) JP3184534B2 (es)
KR (1) KR100209469B1 (es)
AU (1) AU3618795A (es)
DE (1) DE69524614T2 (es)
ES (1) ES2167463T3 (es)
TW (1) TW492870B (es)
WO (1) WO1996011022A1 (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19700913C2 (de) * 1997-01-14 2001-01-04 Lohmann Therapie Syst Lts Transdermales therapeutisches System zur Abgabe von Hormonen
DE19830732B4 (de) * 1998-07-09 2008-11-13 Lts Lohmann Therapie-Systeme Ag Zusammensetzung, enthaltend mindestens einen die Blutfettwerte beeinflussenden Wirkstoff und seine Verwendung
IT1309588B1 (it) * 1999-03-05 2002-01-24 Altergon Sa Cerotto con spessore sottile contenente betametasone ed acidoialuronico per il trattamento di psoriasi, dermatite, dermatosi.
JP4584381B2 (ja) * 1999-07-30 2010-11-17 久光製薬株式会社 フェルビナク含有貼付剤
AU2001253782B2 (en) * 2000-04-26 2006-06-29 Allergan Sales, Llc Minimizing adverse experience associated with oxybutynin therapy
US7029694B2 (en) * 2000-04-26 2006-04-18 Watson Laboratories, Inc. Compositions and methods for transdermal oxybutynin therapy
US7179483B2 (en) * 2000-04-26 2007-02-20 Watson Pharmaceuticals, Inc. Compositions and methods for transdermal oxybutynin therapy
US6761900B2 (en) 2001-03-12 2004-07-13 Teikoku Pharma Usa, Inc. Topical patch preparation containing a delayed-type hypersensitivity inducer and methods for using the same
JP4963776B2 (ja) * 2002-03-08 2012-06-27 第一三共ヘルスケア株式会社 抗真菌活性増強型組成物及び抗真菌活性増強方法
DE10236319A1 (de) * 2002-08-08 2004-02-19 Beiersdorf Ag Hautfreundliche Wirkstoffpflaster auf der Basis von SBC mit mindestens einem pharmazeutischen Wirkstoff mit einem Gehalt von mindestens 34 Gew.-% und dessen Herstellung
US20050191339A1 (en) * 2002-08-08 2005-09-01 Beiersdorf Ag Skin friendly active ingredient plaster based on SBC, containing at least 34 WT.% of a pharmaceutical active ingredient and production thereof
TWI327074B (en) * 2003-05-07 2010-07-11 Hisamitsu Pharmaceutical Co Ultra violet shielding patch
US20060140820A1 (en) * 2004-12-28 2006-06-29 Udo Mattern Use of a container of an inorganic additive containing plastic material
AU2005323206C1 (en) * 2005-01-04 2010-01-07 Teikoku Pharma Usa, Inc. Cooling topical patch preparation
US20060263420A1 (en) * 2005-03-10 2006-11-23 Hisamitsu Pharmaceutical Co., Inc. Adhesive and plaster
KR101217407B1 (ko) * 2005-04-20 2013-01-02 센주세이야쿠 가부시키가이샤 경피흡수제제
EP1940377A4 (en) * 2005-10-24 2010-12-08 Teikoku Pharma Usa Inc TOPICAL AEROSPECTIVE COMPOSITIONS OF N, 2,3-TRIMETHYL-2-ISOPROPYLBUTAMIDE AND METHOD OF USE THEREOF
PL2068825T3 (pl) 2006-10-04 2011-06-30 M & P Patent Ag Układ dostarczania o kontrolowanym uwalnianiu do donosowego podawania związków neuroprzekaźnikowych
JP5242950B2 (ja) * 2007-06-15 2013-07-24 日東電工株式会社 ゲル組成物およびその用途
WO2009025854A1 (en) * 2007-08-22 2009-02-26 Burnham Institute For Medical Research Smips: small molecule inhibitors of p27 depletion in cancers and other proliferative diseases
JP4879928B2 (ja) 2008-03-25 2012-02-22 帝國製薬株式会社 ケトプロフェンリジン塩を含有する水性貼付剤
JP5781097B2 (ja) * 2011-01-24 2015-09-16 ニプロパッチ株式会社 含水系貼付剤
US20130040923A1 (en) 2011-05-13 2013-02-14 Trimel Pharmaceuticals Corporation Intranasal lower dosage strength testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder
US9757388B2 (en) 2011-05-13 2017-09-12 Acerus Pharmaceuticals Srl Intranasal methods of treating women for anorgasmia with 0.6% and 0.72% testosterone gels
US20130045958A1 (en) 2011-05-13 2013-02-21 Trimel Pharmaceuticals Corporation Intranasal 0.15% and 0.24% testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder
US9211397B2 (en) * 2012-12-19 2015-12-15 Senju Usa, Inc. Patch for treatment of eyelid disease containing clobetasol
US11744838B2 (en) 2013-03-15 2023-09-05 Acerus Biopharma Inc. Methods of treating hypogonadism with transnasal testosterone bio-adhesive gel formulations in male with allergic rhinitis, and methods for preventing an allergic rhinitis event
WO2019026844A1 (ja) 2017-08-01 2019-02-07 久光製薬株式会社 貼付剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5842168B2 (ja) * 1974-12-20 1983-09-17 トウコウヤクヒンコウギヨウ カブシキガイシヤ 局所用剤の製造方法
DK243084A (da) * 1983-05-26 1984-11-27 Takeda Chemical Industries Ltd Perkutane farmaceutiske praeparater til udvortes brug
US4752612A (en) * 1983-07-01 1988-06-21 Nitto Electrical Industrial Co., Ltd. Method and percutaneously administering physiologically active agents using an alcohol adjuvant and a solvent
JPS62240628A (ja) * 1986-03-26 1987-10-21 Kao Corp 経皮吸収促進剤およびこれを含有する外用剤
US5162315A (en) * 1989-05-08 1992-11-10 Rajadhyaksha Vithal J Penetration enhancers

Also Published As

Publication number Publication date
KR970706021A (ko) 1997-11-03
DE69524614T2 (de) 2002-09-12
DE69524614D1 (de) 2002-01-24
EP0782861A4 (en) 1998-01-14
AU3618795A (en) 1996-05-02
JP3184534B2 (ja) 2001-07-09
WO1996011022A1 (fr) 1996-04-18
US5891920A (en) 1999-04-06
EP0782861A1 (en) 1997-07-09
EP0782861B1 (en) 2001-12-12
TW492870B (en) 2002-07-01
KR100209469B1 (ko) 1999-07-15

Similar Documents

Publication Publication Date Title
ES2167463T3 (es) Componentes de un compuesto medicinal que comprenden derivados n-sustituidos de la o-toluidina y preparacion percutaneamente absorbible.
NL1002835A1 (nl) Synergistisch stabilisatormengsel.
NO914356L (no) Mono n-substituerte 1,4,7,10-tetraazacyklododekanderivater, fremgangsmaater for fremstilling av dem og farmasoeytiskemidler som inneholder dem
DE69528005T2 (de) Prolineamid-Derivate
NO180538C (no) N-sulfonyl-2-oksoindol-derivater som har affinitet for vasopressin- og/eller ocytocin-reseptorer, farmasöytiske blandinger som inneholder dem og mellomprodukter ved fremstilling av derivatene
RU95116357A (ru) Производные пирролидина и тиазолидина, способы их получения, способ разделения энантиомеров и фармацевтическая композиция на основе производных пирролидина и тиазолидина
DE69725608D1 (de) Indolin-2-one derivate, verfahren zu ihrer herstellung und dieseenthaltende arzneimittel
ES2044836T3 (es) Derivado de la piperidina, su utilizacion y compuesto farmaceutico que lo contiene.
EP0201742A3 (en) N-acylpyrrolidine derivatives, processes for preparing them, pharmaceutical composition and use
MY113733A (en) Salts of an anti-migraine indole derivative
ATE338744T1 (de) Hydrazonderivate
EP0630898A4 (en) MEDICINE FOR THROMBOZYTOPENIA.
DK0976748T3 (da) Pyrrolidinderivater med phospholispase A2-hæmmende aktivitet
DK0513351T3 (da) 2-Nitroimidazolderivat, fremstilling deraf og strålingssensibilisator indeholdende samme som aktiv bestanddel
DK0603649T3 (da) Substituerede 4-phenyl-pyridoner og 4-phenyl-2-alkoxypyridiner som HMG-CoA-reduktase-inhibitorer
GEP20002187B (en) Carboxamide Derivatives of Pyrrolidine, Piperidine and Hexahydroazepine, Composition for the Treatment of Thrombosis Disorders Induced by Thrombocytes, Intermediate Compounds and Method for Their Preparation
NO923721L (no) 4-desoksy-4-epipodophyllotoxin-derivat eller farmasoeytiskakseptabelt salt derav
ATE66675T1 (de) Stickstoffhaltige heterozyklische verbindungen.
MD1560F2 (en) Cyclic compounds, pharmaceutical compositions on base thereof and methods of treatment of infections or diseases provoked by retroviruses.
RU94038042A (ru) Производные гексагидроазепинов, фармацевтическая композиция на их основе и антипсихотропный агент
PT91203A (pt) Processo para a preparacao de novos derivados de antibioticos bu-3608 e de composicoes farmaceuticas que os contem
EP0816366A4 (en) IMIDAZOTHIAZOL COMPOUNDS
TW344743B (en) Therapeutic nucleosides
ES2157498T3 (es) Derivados de triazol o sus sales.
DE3880564D1 (de) Arzneimittel zur behandlung von herzinsuffizienz.