DK0487071T3 - Kondenserede heterocykliske forbindelser, deres fremstilling og anvendelse - Google Patents
Kondenserede heterocykliske forbindelser, deres fremstilling og anvendelseInfo
- Publication number
- DK0487071T3 DK0487071T3 DK91119818.2T DK91119818T DK0487071T3 DK 0487071 T3 DK0487071 T3 DK 0487071T3 DK 91119818 T DK91119818 T DK 91119818T DK 0487071 T3 DK0487071 T3 DK 0487071T3
- Authority
- DK
- Denmark
- Prior art keywords
- substituted
- condensed heterocyclic
- preparation
- whole number
- heterocyclic compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Containers Having Bodies Formed In One Piece (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP31989790 | 1990-11-22 | ||
| JP7028691 | 1991-01-14 | ||
| JP20935891 | 1991-08-21 | ||
| JP24376891 | 1991-09-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0487071T3 true DK0487071T3 (da) | 1995-10-30 |
Family
ID=27465225
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91119818.2T DK0487071T3 (da) | 1990-11-22 | 1991-11-21 | Kondenserede heterocykliske forbindelser, deres fremstilling og anvendelse |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5273974A (enExample) |
| EP (1) | EP0487071B1 (enExample) |
| JP (1) | JP2650537B2 (enExample) |
| KR (1) | KR100211437B1 (enExample) |
| CN (1) | CN1036458C (enExample) |
| AT (1) | ATE124695T1 (enExample) |
| AU (1) | AU643337B2 (enExample) |
| CA (1) | CA2055947C (enExample) |
| DE (1) | DE69111029T2 (enExample) |
| DK (1) | DK0487071T3 (enExample) |
| ES (1) | ES2074205T3 (enExample) |
| FI (2) | FI102965B1 (enExample) |
| GR (1) | GR3017366T3 (enExample) |
| HU (2) | HU214573B (enExample) |
| IE (1) | IE68346B1 (enExample) |
| NO (1) | NO179868C (enExample) |
| NZ (1) | NZ240676A (enExample) |
| RU (1) | RU2095361C1 (enExample) |
| TW (1) | TW197435B (enExample) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW263504B (enExample) | 1991-10-03 | 1995-11-21 | Pfizer | |
| US5965574A (en) * | 1996-08-13 | 1999-10-12 | Chen; Yuhpyng Liang | Heteroaryl amines as novel acetylcholinesterase inhibitors |
| TW218875B (enExample) * | 1992-03-09 | 1994-01-11 | Takeda Pharm Industry Co Ltd | |
| US5462934A (en) * | 1992-03-09 | 1995-10-31 | Takeda Chemical Industries | Condensed heterocyclic ketone derivatives and their use |
| EP0567090B1 (en) | 1992-04-24 | 2000-07-26 | Takeda Chemical Industries, Ltd. | Benzoxazepine derivatives as cholinesterase inhibitors |
| TW248556B (enExample) * | 1993-01-18 | 1995-06-01 | Takeda Pharm Industry Co | |
| US5620973A (en) * | 1993-11-30 | 1997-04-15 | Takeda Chemical Industries, Ltd. | Tetracyclic condensed heterocyclic compounds and their use |
| BR9508436A (pt) * | 1994-07-27 | 1998-07-14 | Procter & Gamble | Dihidro benzofurando e compostos correlacionados úteis como agentes anti-inflamatórios |
| US5674891A (en) * | 1994-07-27 | 1997-10-07 | The Procter & Gamble Company | Dihydrobenzothiophene compounds useful as anti-inflammatory agents |
| US5684031A (en) * | 1996-02-01 | 1997-11-04 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
| US5672620A (en) * | 1996-02-01 | 1997-09-30 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
| US6251938B1 (en) | 1996-12-18 | 2001-06-26 | Teva Pharmaceutical Industries, Ltd., | Phenylethylamine derivatives |
| WO1998027055A1 (en) | 1996-12-18 | 1998-06-25 | Teva Pharmaceutical Industries, Ltd. | Aminoindan derivatives |
| US5962535A (en) * | 1997-01-17 | 1999-10-05 | Takeda Chemical Industries, Ltd. | Composition for alzheimer's disease |
| EP0952826B1 (en) * | 1997-01-17 | 2001-11-14 | Takeda Chemical Industries, Ltd. | Idebenone containing combination agent for treating alzheimer's disease |
| CA2282390A1 (en) | 1997-04-17 | 1998-10-22 | Yukio Fujisawa | Thermogenic composition and benzazepine thermogenics |
| RU2222815C2 (ru) * | 1997-10-09 | 2004-01-27 | Дексел Фарма Текнолоджис Элтиди. | Лекарственная форма для доставки и непосредственного локализованного освобождения желаемого агента в желудочно-кишечном тракте животного и способ доставки желаемого агента в желудочно-кишечный тракт животного (варианты) |
| BR9814300A (pt) * | 1997-12-19 | 2002-02-05 | Searle & Co | Método de preparação de óxidos de tetraidrobenzotiepina enanciomericamente enriquecidos |
| AU3534799A (en) | 1998-04-23 | 1999-11-08 | Takeda Chemical Industries Ltd. | Pharmaceutical composition for neurotrophic action |
| EP1118322A4 (en) | 1998-09-30 | 2004-10-20 | Takeda Chemical Industries Ltd | MEDICINES THAT IMPROVE BLADDER DRAINING POWER |
| KR100694682B1 (ko) * | 1999-03-03 | 2007-03-13 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 4-치환 피페리딘 유도체 불화물 |
| WO2002002530A1 (en) * | 2000-07-04 | 2002-01-10 | Takeda Chemical Industries, Ltd. | Gpr14 antagonist |
| EP1308513A4 (en) * | 2000-08-10 | 2008-07-09 | Takeda Pharmaceutical | APPLICATION OF POLYPEPTIDES |
| CN1317276C (zh) * | 2000-09-29 | 2007-05-23 | 中国科学院上海药物研究所 | 一类吲哚基哌啶类化合物及其制备方法和用途 |
| CN1589153A (zh) | 2001-12-28 | 2005-03-02 | 武田药品工业株式会社 | 排尿紊乱的预防或治疗 |
| US20040010038A1 (en) * | 2002-02-27 | 2004-01-15 | Eran Blaugrund | Propargylamino indan derivatives and propargylamino tetralin derivatives as brain-selective MAO inhibitors |
| MXPA04010308A (es) * | 2002-04-16 | 2005-02-03 | Schering Corp | Antagonistas del receptor de trombina triciclico. |
| IL165589A (en) | 2002-06-14 | 2012-04-30 | Toyama Chemical Co Ltd | Pharmaceutical preparation to improve brain function and use |
| PL220722B1 (pl) | 2002-12-20 | 2015-12-31 | Glaxo Group Ltd | Benzoazepinowe pochodne, zawierająca je kompozycja farmaceutyczna i ich zastosowania do wytwarzania leku i do leczenia chorób neurologicznych |
| WO2006004201A1 (ja) * | 2004-07-01 | 2006-01-12 | Eisai R & D Management Co., Ltd. | 神経再生促進剤 |
| US20080188510A1 (en) * | 2005-05-23 | 2008-08-07 | Eisai R & D Management Co., Ltd. | Novel methods using zonisamide |
| WO2007070425A2 (en) * | 2005-12-09 | 2007-06-21 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Use of low-dose ladostigil for neuroprotection |
| TW200744576A (en) * | 2006-02-24 | 2007-12-16 | Teva Pharma | Propargylated aminoindans, processes for preparation, and uses thereof |
| WO2010007382A1 (en) * | 2008-07-18 | 2010-01-21 | Takeda Pharmaceutical Company Limited. | Benzazepine derivatives and their use as hstamine h3 antagonists |
| CA2789014C (en) | 2010-02-09 | 2019-01-15 | Michela Gallagher | Methods and compositions for improving cognitive function |
| JP6440625B2 (ja) | 2012-11-14 | 2018-12-19 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 精神分裂病を処置するための方法および組成物 |
| HK1218623A1 (zh) | 2013-03-15 | 2017-03-03 | 艾吉因生物股份有限公司 | 用於改善認知功能的方法和組合物 |
| WO2014144663A1 (en) | 2013-03-15 | 2014-09-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| US10925834B2 (en) | 2015-05-22 | 2021-02-23 | Agenebio, Inc. | Extended release pharmaceutical compositions of levetiracetam |
| CN109880635B (zh) * | 2019-03-19 | 2021-02-02 | 石家庄晶奥量新材料有限公司 | 含有二苯并呋喃并含氧杂环类液晶化合物和组合物及应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2334358A1 (fr) * | 1975-12-12 | 1977-07-08 | Sogeras | Nouveaux medicaments derives de l'indole |
| US4208417A (en) * | 1978-06-29 | 1980-06-17 | Pharmindustrie | Indole derivatives and their use as anxiolytics |
| DK623586A (da) * | 1985-12-27 | 1987-06-28 | Eisai Co Ltd | Piperidinderivater eller salte deraf og farmaceutiske kompositioner indeholdende forbindelserne |
| KR910006138B1 (ko) * | 1986-09-30 | 1991-08-16 | 에자이 가부시끼가이샤 | 환상아민 유도체 |
| FI95572C (fi) * | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
| FR2640266B2 (fr) * | 1988-07-12 | 1992-07-10 | Synthelabo | Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2, quinoleinones-2, benzo(b)azepinones-2 et benzimidazolones-2, leur preparation et leur application en therapeutique |
| JP2969359B2 (ja) * | 1989-01-13 | 1999-11-02 | 武田薬品工業株式会社 | 環状アミン化合物 |
| CA2023492A1 (en) * | 1989-08-31 | 1991-03-01 | Barry Clifford Lange | Herbicidal glutarimides |
| US5109002A (en) * | 1989-09-08 | 1992-04-28 | Du Pont Merck Pharmaceutical Company | Antipsychotic 1-cycloalkylpiperidines |
-
1991
- 1991-11-19 TW TW080109059A patent/TW197435B/zh active
- 1991-11-20 JP JP3305062A patent/JP2650537B2/ja not_active Expired - Fee Related
- 1991-11-20 NZ NZ240676A patent/NZ240676A/xx unknown
- 1991-11-21 AT AT91119818T patent/ATE124695T1/de not_active IP Right Cessation
- 1991-11-21 DE DE69111029T patent/DE69111029T2/de not_active Expired - Fee Related
- 1991-11-21 FI FI915488A patent/FI102965B1/fi active
- 1991-11-21 ES ES91119818T patent/ES2074205T3/es not_active Expired - Lifetime
- 1991-11-21 DK DK91119818.2T patent/DK0487071T3/da active
- 1991-11-21 EP EP91119818A patent/EP0487071B1/en not_active Expired - Lifetime
- 1991-11-21 AU AU88045/91A patent/AU643337B2/en not_active Ceased
- 1991-11-21 CA CA002055947A patent/CA2055947C/en not_active Expired - Fee Related
- 1991-11-21 FI FI982436A patent/FI982436A7/fi unknown
- 1991-11-21 HU HU643/91A patent/HU214573B/hu not_active IP Right Cessation
- 1991-11-21 NO NO914558A patent/NO179868C/no not_active IP Right Cessation
- 1991-11-21 IE IE405391A patent/IE68346B1/en not_active IP Right Cessation
- 1991-11-21 RU SU915010491A patent/RU2095361C1/ru active
- 1991-11-22 KR KR1019910020944A patent/KR100211437B1/ko not_active Expired - Fee Related
- 1991-11-22 CN CN 91110950 patent/CN1036458C/zh not_active Expired - Fee Related
- 1991-11-22 US US07/796,430 patent/US5273974A/en not_active Expired - Lifetime
-
1995
- 1995-04-28 HU HU95P/P00115P patent/HU211130A9/hu unknown
- 1995-09-13 GR GR950402483T patent/GR3017366T3/el unknown
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