DK0460042T3 - Vektor til integrationsstedsuafhængig genekspression i pattedyrværtsceller - Google Patents

Vektor til integrationsstedsuafhængig genekspression i pattedyrværtsceller

Info

Publication number
DK0460042T3
DK0460042T3 DK90903867T DK90903867T DK0460042T3 DK 0460042 T3 DK0460042 T3 DK 0460042T3 DK 90903867 T DK90903867 T DK 90903867T DK 90903867 T DK90903867 T DK 90903867T DK 0460042 T3 DK0460042 T3 DK 0460042T3
Authority
DK
Denmark
Prior art keywords
site
gene
lambda
downstream
vector
Prior art date
Application number
DK90903867T
Other languages
Danish (da)
English (en)
Inventor
Sarah Jane Flat Woodlan Eccles
Franklin Gerardus Grosveld
Original Assignee
Medical Res Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Res Council filed Critical Medical Res Council
Application granted granted Critical
Publication of DK0460042T3 publication Critical patent/DK0460042T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Image Analysis (AREA)
  • Devices For Executing Special Programs (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
DK90903867T 1989-02-22 1990-02-22 Vektor til integrationsstedsuafhængig genekspression i pattedyrværtsceller DK0460042T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898904009A GB8904009D0 (en) 1989-02-22 1989-02-22 Vector
PCT/GB1990/000286 WO1990010077A1 (fr) 1989-02-22 1990-02-22 Vecteur d'integration d'une expression genetique independante du site dans les cellules hotes de mammifere

Publications (1)

Publication Number Publication Date
DK0460042T3 true DK0460042T3 (da) 2000-07-31

Family

ID=10652102

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90903867T DK0460042T3 (da) 1989-02-22 1990-02-22 Vektor til integrationsstedsuafhængig genekspression i pattedyrværtsceller

Country Status (10)

Country Link
EP (2) EP0962534A3 (fr)
JP (1) JPH04505552A (fr)
AT (1) ATE192498T1 (fr)
AU (2) AU5161490A (fr)
CA (2) CA2050920A1 (fr)
DE (1) DE69033531T2 (fr)
DK (1) DK0460042T3 (fr)
ES (1) ES2150411T3 (fr)
GB (1) GB8904009D0 (fr)
WO (1) WO1990010077A1 (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9027917D0 (en) * 1990-12-21 1991-02-13 Ici Plc Expression systems
DE4228162C1 (de) 1992-08-25 1994-01-13 Rajewsky Klaus Dr Verfahren zum Ersetzen homologer Genabschnitte aus Säugern in der Keimbahn von nicht-menschlichen Säugern
DE19541450C2 (de) * 1995-11-07 1997-10-02 Gsf Forschungszentrum Umwelt Genkonstrukt und dessen Verwendung
CA2337422C (fr) 1998-08-18 2010-11-02 The Regents Of The University Of California Inhibition de la production de mucus dans les voies respiratoires par l'administration d'antagonistes d'egf-r
EP1305412A2 (fr) 1999-10-14 2003-05-02 Clontech Laboratories Inc. Chromo/fluoro-proteines derivees d'anthozoa et methodes d'utilisation
JP2003000243A (ja) 2001-06-25 2003-01-07 Takachika Azuma 変異体の製造法
JP4700281B2 (ja) 2001-12-19 2011-06-15 ザ・ユニバーシティ・オブ・シカゴ 急速に成熟する蛍光タンパク質およびその使用法
US7585501B2 (en) 2002-06-14 2009-09-08 Stowers Institute For Medical Research Compositions and methods for treating kidney disease
EP2390262A1 (fr) 2003-05-16 2011-11-30 Intermune, Inc. Ligands de récepteur de chimiokine synthétique et leurs procédés d'utilisation
CN102020697B (zh) 2003-10-14 2014-10-29 F·霍夫曼-罗须公司 作为hcv复制抑制剂的巨环羧酸和酰基磺酰胺
EP1732944B1 (fr) 2004-04-07 2012-09-05 The University of Chicago Proteines monomeres fluorescentes rouges
US7597884B2 (en) 2004-08-09 2009-10-06 Alios Biopharma, Inc. Hyperglycosylated polypeptide variants and methods of use
WO2007137163A2 (fr) 2006-05-19 2007-11-29 Georgia Tech Research Corporation Ligand des transporteurs abc
US8324158B2 (en) 2006-07-14 2012-12-04 Georgia Tech Research Corporation Methods for inhibiting CLC-2 channel with GATX2
WO2008094316A2 (fr) 2006-09-22 2008-08-07 Stowers Institute Of Medical Research Nouvelles protéines fluorescentes dérivées du genre branchiostoma
WO2009059305A2 (fr) 2007-11-01 2009-05-07 The University Of Chicago Protéines fluorescentes rouges avec expression bactérienne amplifiée, luminosité accrue et agrégation réduite
EP2341924A4 (fr) 2008-10-02 2013-01-23 David Gladstone Inst Méthodes de traitement d une infection par le virus de l hépatite c
JP5827127B2 (ja) 2008-12-18 2015-12-02 エラスムス・ユニヴァーシティ・メディカル・センター・ロッテルダム ヒト化抗体を発現する非ヒトトランスジェニック動物及びその使用
CN102740887B (zh) 2009-09-30 2015-04-15 斯隆凯特林防癌纪念中心 用于治疗癌症的组合免疫疗法
US10662256B2 (en) 2010-07-26 2020-05-26 Trianni, Inc. Transgenic mammals and methods of use thereof
CA2806233C (fr) 2010-07-26 2021-12-07 Trianni, Inc. Animaux transgeniques et methodes d'utilisation
US10793829B2 (en) 2010-07-26 2020-10-06 Trianni, Inc. Transgenic mammals and methods of use thereof
US9980470B2 (en) 2013-03-14 2018-05-29 Erasmus University Medical Center Antibody production
WO2021003149A1 (fr) 2019-07-01 2021-01-07 Trianni, Inc. Animaux transgéniques et leurs procédés d'utilisation
KR20220025839A (ko) 2019-07-01 2022-03-03 트리아니, 인코포레이티드 유전자이식 포유동물 및 이의 사용 방법
CN111424054B (zh) * 2020-04-21 2021-08-27 鲲石生物科技(深圳)有限公司 改进的大型载体在人类细胞中传递方法的发现及应用
CN114763558B (zh) 2021-01-14 2024-02-20 上海泰槿生物技术有限公司 重组基因组、非人哺乳动物细胞及其产生方法和用途
CA3216988A1 (fr) 2021-05-05 2022-11-10 Werner Mueller Rongeurs transgeniques exprimant des anticorps chimeriques de rongeurs-equins et leurs methodes d'utilisation
CA3235395A1 (fr) 2021-11-10 2023-05-19 Peter Burrows Mammiferes transgeniques et leurs procedes d'utilisation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988005083A1 (fr) * 1986-12-24 1988-07-14 Whitehead Institute For Biomedical Research Methode d'expression de gene inductible
DE3724482C2 (de) * 1987-07-24 1995-12-14 Boehringer Mannheim Gmbh Verfahren zur Erweiterung der Zellspezifität von eukaryotischen Expressionsvektoren

Also Published As

Publication number Publication date
ATE192498T1 (de) 2000-05-15
ES2150411T3 (es) 2000-12-01
WO1990010077A1 (fr) 1990-09-07
EP0460042A1 (fr) 1991-12-11
JPH04505552A (ja) 1992-10-01
AU5161490A (en) 1990-09-26
AU672910B2 (en) 1996-10-17
DE69033531D1 (de) 2000-06-08
EP0962534A3 (fr) 1999-12-22
DE69033531T2 (de) 2001-01-11
GB8904009D0 (en) 1989-04-05
AU6872694A (en) 1994-11-17
CA2050920A1 (fr) 1990-08-23
CA2297385A1 (fr) 1990-08-23
EP0962534A2 (fr) 1999-12-08
EP0460042B1 (fr) 2000-05-03

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