DK0428486T3 - Polymyxin-konjugater - Google Patents
Polymyxin-konjugaterInfo
- Publication number
- DK0428486T3 DK0428486T3 DK90810872.3T DK90810872T DK0428486T3 DK 0428486 T3 DK0428486 T3 DK 0428486T3 DK 90810872 T DK90810872 T DK 90810872T DK 0428486 T3 DK0428486 T3 DK 0428486T3
- Authority
- DK
- Denmark
- Prior art keywords
- polymyxin
- conjugates
- polymyxin conjugates
- bloodstream
- potent
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43748789A | 1989-11-15 | 1989-11-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0428486T3 true DK0428486T3 (da) | 1995-01-09 |
Family
ID=23736660
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90810872.3T DK0428486T3 (da) | 1989-11-15 | 1990-11-13 | Polymyxin-konjugater |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0428486B1 (ko) |
| JP (1) | JPH082917B2 (ko) |
| KR (1) | KR0184858B1 (ko) |
| AT (1) | ATE111746T1 (ko) |
| AU (1) | AU639952B2 (ko) |
| CA (1) | CA2029997A1 (ko) |
| CY (1) | CY2052B1 (ko) |
| DE (1) | DE69012747T2 (ko) |
| DK (1) | DK0428486T3 (ko) |
| ES (1) | ES2063326T3 (ko) |
| HK (1) | HK49696A (ko) |
| HU (1) | HU210901A9 (ko) |
| IE (1) | IE65268B1 (ko) |
| IL (1) | IL96326A (ko) |
| MY (1) | MY104520A (ko) |
| NZ (1) | NZ236050A (ko) |
| ZA (1) | ZA909187B (ko) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5545721A (en) * | 1992-12-21 | 1996-08-13 | Ophidian Pharmaceuticals, Inc. | Conjugates for the prevention and treatment of sepsis |
| JPH08504824A (ja) * | 1992-12-21 | 1996-05-28 | オフィディアン ファーマシューティカルズ，インコーポレーテッド | 敗血症の予防および治療 |
| US6660267B1 (en) | 1992-12-21 | 2003-12-09 | Promega Corporation | Prevention and treatment of sepsis |
| US6579696B1 (en) * | 1992-12-21 | 2003-06-17 | Promega Corporation | Polymyxin B conjugates |
| US6180134B1 (en) | 1993-03-23 | 2001-01-30 | Sequus Pharmaceuticals, Inc. | Enhanced ciruclation effector composition and method |
| EP0720485B1 (en) * | 1993-09-22 | 2003-11-19 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Method of activating soluble carbohydrate using novel cyanylating reagents for the production of immunogenic constructs |
| US5849301A (en) * | 1993-09-22 | 1998-12-15 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Producing immunogenic constructs using soluable carbohydrates activated via organic cyanylating reagents |
| JP2581425B2 (ja) * | 1993-11-12 | 1997-02-12 | 株式会社島津製作所 | ペプチド合成用支持体及びそれを用いて製造されたペプチド |
| DE122009000056I1 (de) * | 1995-03-22 | 2010-01-28 | Jackson H M Found Military Med | Herstellung von immunogenen konstrukten unter verwendung von löslichen kohlehydraten, die durch organische cyanylierungs-reagenzien aktiviert wurden |
| EP0814833B1 (en) * | 1995-03-22 | 2003-05-28 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Producing immunogenic constructs using soluble carbohydrates activated via organic cyanylating reagents |
| US5691304A (en) * | 1995-05-25 | 1997-11-25 | Novartis Ag | Improved process for preparing polymyxin B/dextran conjugates |
| US6309646B1 (en) | 1996-05-09 | 2001-10-30 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine | Protein-polysaccharide conjugate vaccines and other immunological reagents prepared using homobifunctional and heterobifunctional vinylsulfones, and processes for preparing the conjugates |
| US5998381A (en) * | 1996-12-06 | 1999-12-07 | Ophidian Pharmaceuticals, Inc. | Compounds that bind bacterial pili |
| IT1312110B1 (it) | 1999-05-18 | 2002-04-04 | Istituto Biochimico Pavese Pha | Addotti antibiotico-polimero polisaccaridico naturale |
| DE10129369C1 (de) * | 2001-06-21 | 2003-03-06 | Fresenius Kabi De Gmbh | Wasserlösliches, einen Aminozucker aufweisendes Antibiotikum in Form eines Pol ysaccharid-Konjugats |
| AT507846B1 (de) * | 2009-01-22 | 2011-12-15 | Fresenius Medical Care De Gmbh | Sorptionsmittel für endotoxine |
| PT3200827T (pt) * | 2014-10-03 | 2020-10-08 | Xellia Pharmaceuticals Aps | Composições |
| CN109843315A (zh) * | 2016-10-21 | 2019-06-04 | 阿尔吉法玛公司 | 多粘菌素-藻酸盐低聚物缀合物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE7702261L (sv) * | 1976-03-02 | 1977-09-07 | Pharmaco Inc | Forfarande for att immobilisera antimikrobiella emnen |
| JPS5813519A (ja) * | 1981-07-16 | 1983-01-26 | Seikagaku Kogyo Co Ltd | エンドトキシン吸着材及びそれを用いるエンドトキシンの除去方法 |
| US4496689A (en) * | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
-
1990
- 1990-11-13 AU AU66555/90A patent/AU639952B2/en not_active Ceased
- 1990-11-13 DE DE69012747T patent/DE69012747T2/de not_active Expired - Fee Related
- 1990-11-13 ES ES90810872T patent/ES2063326T3/es not_active Expired - Lifetime
- 1990-11-13 IL IL9632690A patent/IL96326A/en unknown
- 1990-11-13 MY MYPI90002000A patent/MY104520A/en unknown
- 1990-11-13 NZ NZ236050A patent/NZ236050A/xx unknown
- 1990-11-13 JP JP2304230A patent/JPH082917B2/ja not_active Expired - Lifetime
- 1990-11-13 AT AT90810872T patent/ATE111746T1/de not_active IP Right Cessation
- 1990-11-13 EP EP90810872A patent/EP0428486B1/en not_active Expired - Lifetime
- 1990-11-13 DK DK90810872.3T patent/DK0428486T3/da active
- 1990-11-14 CA CA002029997A patent/CA2029997A1/en not_active Abandoned
- 1990-11-14 KR KR1019900018434A patent/KR0184858B1/ko not_active IP Right Cessation
- 1990-11-14 IE IE410590A patent/IE65268B1/en not_active IP Right Cessation
- 1990-11-15 ZA ZA909187A patent/ZA909187B/xx unknown
-
1995
- 1995-06-02 HU HU95P/P00162P patent/HU210901A9/hu unknown
-
1996
- 1996-03-21 HK HK49696A patent/HK49696A/xx not_active IP Right Cessation
-
1998
- 1998-04-30 CY CY9802052A patent/CY2052B1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2029997A1 (en) | 1991-05-16 |
| IL96326A0 (en) | 1991-08-16 |
| AU6655590A (en) | 1991-05-23 |
| EP0428486A1 (en) | 1991-05-22 |
| JPH082917B2 (ja) | 1996-01-17 |
| AU639952B2 (en) | 1993-08-12 |
| NZ236050A (en) | 1993-04-28 |
| KR0184858B1 (ko) | 1999-05-01 |
| ATE111746T1 (de) | 1994-10-15 |
| EP0428486B1 (en) | 1994-09-21 |
| ES2063326T3 (es) | 1995-01-01 |
| IE904105A1 (en) | 1991-05-22 |
| MY104520A (en) | 1994-04-30 |
| HU210901A9 (en) | 1995-09-28 |
| CY2052B1 (en) | 1998-04-30 |
| KR910009274A (ko) | 1991-06-28 |
| IL96326A (en) | 1995-07-31 |
| IE65268B1 (en) | 1995-10-18 |
| JPH03220198A (ja) | 1991-09-27 |
| DE69012747D1 (de) | 1994-10-27 |
| ZA909187B (en) | 1992-07-29 |
| HK49696A (en) | 1996-03-29 |
| DE69012747T2 (de) | 1995-03-16 |
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