DK0428486T3 - Polymyxin-konjugater - Google Patents
Polymyxin-konjugaterInfo
- Publication number
- DK0428486T3 DK0428486T3 DK90810872.3T DK90810872T DK0428486T3 DK 0428486 T3 DK0428486 T3 DK 0428486T3 DK 90810872 T DK90810872 T DK 90810872T DK 0428486 T3 DK0428486 T3 DK 0428486T3
- Authority
- DK
- Denmark
- Prior art keywords
- polymyxin
- conjugates
- polymyxin conjugates
- bloodstream
- potent
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43748789A | 1989-11-15 | 1989-11-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0428486T3 true DK0428486T3 (da) | 1995-01-09 |
Family
ID=23736660
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90810872.3T DK0428486T3 (da) | 1989-11-15 | 1990-11-13 | Polymyxin-konjugater |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0428486B1 (da) |
| JP (1) | JPH082917B2 (da) |
| KR (1) | KR0184858B1 (da) |
| AT (1) | ATE111746T1 (da) |
| AU (1) | AU639952B2 (da) |
| CA (1) | CA2029997A1 (da) |
| CY (1) | CY2052B1 (da) |
| DE (1) | DE69012747T2 (da) |
| DK (1) | DK0428486T3 (da) |
| ES (1) | ES2063326T3 (da) |
| HK (1) | HK49696A (da) |
| HU (1) | HU210901A9 (da) |
| IE (1) | IE65268B1 (da) |
| IL (1) | IL96326A (da) |
| MY (1) | MY104520A (da) |
| NZ (1) | NZ236050A (da) |
| ZA (1) | ZA909187B (da) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6660267B1 (en) | 1992-12-21 | 2003-12-09 | Promega Corporation | Prevention and treatment of sepsis |
| US6579696B1 (en) * | 1992-12-21 | 2003-06-17 | Promega Corporation | Polymyxin B conjugates |
| US5545721A (en) * | 1992-12-21 | 1996-08-13 | Ophidian Pharmaceuticals, Inc. | Conjugates for the prevention and treatment of sepsis |
| EP0679083A4 (en) * | 1992-12-21 | 1999-03-24 | Ophidian Pharm Inc | PREVENTION AND TREATMENT OF SEPTICEMIA. |
| US6180134B1 (en) | 1993-03-23 | 2001-01-30 | Sequus Pharmaceuticals, Inc. | Enhanced ciruclation effector composition and method |
| ATE254475T1 (de) * | 1993-09-22 | 2003-12-15 | Jackson H M Found Military Med | Verfahren zur aktivierung von löslichem kohlenhydraten durch verwendung von neuen cyanylierungsreagenzien, zur herstellung von immunogenischen konstrukten |
| US5849301A (en) * | 1993-09-22 | 1998-12-15 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Producing immunogenic constructs using soluable carbohydrates activated via organic cyanylating reagents |
| JP2581425B2 (ja) * | 1993-11-12 | 1997-02-12 | 株式会社島津製作所 | ペプチド合成用支持体及びそれを用いて製造されたペプチド |
| ES2200059T3 (es) * | 1995-03-22 | 2004-03-01 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Produccion de construcciones inmunogenicas usando carbohidratos solubles activados mediante reactivos cianilados organicos. |
| DE122009000056I1 (de) * | 1995-03-22 | 2010-01-28 | Jackson H M Found Military Med | Herstellung von immunogenen konstrukten unter verwendung von löslichen kohlehydraten, die durch organische cyanylierungs-reagenzien aktiviert wurden |
| US5691304A (en) * | 1995-05-25 | 1997-11-25 | Novartis Ag | Improved process for preparing polymyxin B/dextran conjugates |
| US6309646B1 (en) | 1996-05-09 | 2001-10-30 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine | Protein-polysaccharide conjugate vaccines and other immunological reagents prepared using homobifunctional and heterobifunctional vinylsulfones, and processes for preparing the conjugates |
| US5998381A (en) * | 1996-12-06 | 1999-12-07 | Ophidian Pharmaceuticals, Inc. | Compounds that bind bacterial pili |
| IT1312110B1 (it) | 1999-05-18 | 2002-04-04 | Istituto Biochimico Pavese Pha | Addotti antibiotico-polimero polisaccaridico naturale |
| DE10129369C1 (de) * | 2001-06-21 | 2003-03-06 | Fresenius Kabi De Gmbh | Wasserlösliches, einen Aminozucker aufweisendes Antibiotikum in Form eines Pol ysaccharid-Konjugats |
| AT507846B1 (de) * | 2009-01-22 | 2011-12-15 | Fresenius Medical Care De Gmbh | Sorptionsmittel für endotoxine |
| JP6633061B2 (ja) * | 2014-10-03 | 2020-01-22 | クセリア ファーマシューティカルズ エーピーエスＸｅｌｌｉａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ ＡｐＳ | 組成物 |
| CA3040795A1 (en) * | 2016-10-21 | 2018-04-26 | Algipharma As | Polymyxin-alginate oligomer conjugates |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE7702261L (sv) * | 1976-03-02 | 1977-09-07 | Pharmaco Inc | Forfarande for att immobilisera antimikrobiella emnen |
| JPS5813519A (ja) * | 1981-07-16 | 1983-01-26 | Seikagaku Kogyo Co Ltd | エンドトキシン吸着材及びそれを用いるエンドトキシンの除去方法 |
| US4496689A (en) * | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
-
1990
- 1990-11-13 AT AT90810872T patent/ATE111746T1/de not_active IP Right Cessation
- 1990-11-13 AU AU66555/90A patent/AU639952B2/en not_active Ceased
- 1990-11-13 JP JP2304230A patent/JPH082917B2/ja not_active Expired - Lifetime
- 1990-11-13 NZ NZ236050A patent/NZ236050A/xx unknown
- 1990-11-13 IL IL9632690A patent/IL96326A/en unknown
- 1990-11-13 ES ES90810872T patent/ES2063326T3/es not_active Expired - Lifetime
- 1990-11-13 EP EP90810872A patent/EP0428486B1/en not_active Expired - Lifetime
- 1990-11-13 MY MYPI90002000A patent/MY104520A/en unknown
- 1990-11-13 DE DE69012747T patent/DE69012747T2/de not_active Expired - Fee Related
- 1990-11-13 DK DK90810872.3T patent/DK0428486T3/da active
- 1990-11-14 IE IE410590A patent/IE65268B1/en not_active IP Right Cessation
- 1990-11-14 KR KR1019900018434A patent/KR0184858B1/ko not_active IP Right Cessation
- 1990-11-14 CA CA002029997A patent/CA2029997A1/en not_active Abandoned
- 1990-11-15 ZA ZA909187A patent/ZA909187B/xx unknown
-
1995
- 1995-06-02 HU HU95P/P00162P patent/HU210901A9/hu unknown
-
1996
- 1996-03-21 HK HK49696A patent/HK49696A/xx not_active IP Right Cessation
-
1998
- 1998-04-30 CY CY9802052A patent/CY2052B1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL96326A0 (en) | 1991-08-16 |
| JPH082917B2 (ja) | 1996-01-17 |
| AU6655590A (en) | 1991-05-23 |
| CY2052B1 (en) | 1998-04-30 |
| IL96326A (en) | 1995-07-31 |
| HK49696A (en) | 1996-03-29 |
| KR0184858B1 (ko) | 1999-05-01 |
| IE65268B1 (en) | 1995-10-18 |
| ATE111746T1 (de) | 1994-10-15 |
| CA2029997A1 (en) | 1991-05-16 |
| DE69012747T2 (de) | 1995-03-16 |
| NZ236050A (en) | 1993-04-28 |
| DE69012747D1 (de) | 1994-10-27 |
| ES2063326T3 (es) | 1995-01-01 |
| JPH03220198A (ja) | 1991-09-27 |
| MY104520A (en) | 1994-04-30 |
| EP0428486B1 (en) | 1994-09-21 |
| AU639952B2 (en) | 1993-08-12 |
| ZA909187B (en) | 1992-07-29 |
| KR910009274A (ko) | 1991-06-28 |
| HU210901A9 (en) | 1995-09-28 |
| IE904105A1 (en) | 1991-05-22 |
| EP0428486A1 (en) | 1991-05-22 |
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