DK0414606T3 - Omega-Phenylaminoalkansyrer, som i den aromatiske ring er substitueret med en gruppe afledt af 19-nor-steroider, deres salte, en fremgangsmåde til deres fremstilling og mellemprodukter ved denne fremgangsmåde, deres anvendelse som lægemidler og præparater med indhold deraf - Google Patents

Omega-Phenylaminoalkansyrer, som i den aromatiske ring er substitueret med en gruppe afledt af 19-nor-steroider, deres salte, en fremgangsmåde til deres fremstilling og mellemprodukter ved denne fremgangsmåde, deres anvendelse som lægemidler og præparater med indhold deraf

Info

Publication number
DK0414606T3
DK0414606T3 DK90402328.0T DK90402328T DK0414606T3 DK 0414606 T3 DK0414606 T3 DK 0414606T3 DK 90402328 T DK90402328 T DK 90402328T DK 0414606 T3 DK0414606 T3 DK 0414606T3
Authority
DK
Denmark
Prior art keywords
denotes
salts
preparation
phenylaminoalkanoic
norsteroids
Prior art date
Application number
DK90402328.0T
Other languages
Danish (da)
English (en)
Inventor
Daniel Philibert
Lucien Nedelec
Martine Moguilewsky
Francois Nique
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Application granted granted Critical
Publication of DK0414606T3 publication Critical patent/DK0414606T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/42—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of mineralocorticosteroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK90402328.0T 1989-08-23 1990-08-22 Omega-Phenylaminoalkansyrer, som i den aromatiske ring er substitueret med en gruppe afledt af 19-nor-steroider, deres salte, en fremgangsmåde til deres fremstilling og mellemprodukter ved denne fremgangsmåde, deres anvendelse som lægemidler og præparater med indhold deraf DK0414606T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8911173A FR2651233B1 (fr) 1989-08-23 1989-08-23 Nouveaux acides omega-phenylamino alcanouiques substitues sur le noyau aromatique par un radical derive de 19-norsterouides, leur procede de preparation, leur application a titre de medicaments et les compositions les renfermant.

Publications (1)

Publication Number Publication Date
DK0414606T3 true DK0414606T3 (da) 1995-02-27

Family

ID=9384880

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90402328.0T DK0414606T3 (da) 1989-08-23 1990-08-22 Omega-Phenylaminoalkansyrer, som i den aromatiske ring er substitueret med en gruppe afledt af 19-nor-steroider, deres salte, en fremgangsmåde til deres fremstilling og mellemprodukter ved denne fremgangsmåde, deres anvendelse som lægemidler og præparater med indhold deraf

Country Status (19)

Country Link
US (1) US5166146A (pt)
EP (1) EP0414606B1 (pt)
JP (1) JP3026997B2 (pt)
KR (1) KR910004655A (pt)
CN (1) CN1033808C (pt)
AT (1) ATE113605T1 (pt)
AU (1) AU634569B2 (pt)
CA (1) CA2022648A1 (pt)
DE (1) DE69013815T2 (pt)
DK (1) DK0414606T3 (pt)
ES (1) ES2063313T3 (pt)
FR (1) FR2651233B1 (pt)
HU (1) HU208154B (pt)
IE (1) IE65922B1 (pt)
IL (1) IL95451A (pt)
MX (1) MX22020A (pt)
PT (1) PT95066B (pt)
RU (1) RU2041236C1 (pt)
ZA (1) ZA906341B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5780220A (en) * 1994-05-19 1998-07-14 Trustees Of The University Of Pennsylvania Methods and compositions for inhibiting HIV replication
US5639598A (en) * 1994-05-19 1997-06-17 The Trustees Of The University Of Pennsylvania Method and kit for identification of antiviral agents capable of abrogating HIV Vpr-Rip-1 binding interactions
US6090798A (en) * 1997-12-19 2000-07-18 Alcon Laboratories, Inc. Treatment of GLC1A glaucoma with glucocorticoid antagonists
US11103514B2 (en) 2010-05-26 2021-08-31 Corcept Therapeutics, Inc. Treatment of muscular dystrophy
AU2016226451B2 (en) 2015-03-02 2019-12-19 Corcept Therapeutics, Inc. Use of glucocorticoid receptor antagonist and somatostatin analogues to treat ACTH-secreting tumors
ES2906778T3 (es) 2015-03-30 2022-04-20 Corcept Therapeutics Inc Uso de antagonistas del receptor de glucocorticoides en combinación con glucocorticoides para tratar la insuficiencia suprarrenal
KR20180052120A (ko) 2015-08-13 2018-05-17 코어셉트 쎄라퓨틱스, 잉크. Acth-의존성 쿠싱 증후군을 감별 진단하는 방법
CA3011728A1 (en) 2016-01-19 2017-07-27 Corcept Therapeutics, Inc. Differential diagnosis of ectopic cushing's syndrome
US20180148471A1 (en) 2016-11-30 2018-05-31 Arno Therapeutics, Inc. Methods for onapristone synthesis dehydration and deprotection
EP3641780A4 (en) 2017-06-20 2021-02-24 Corcept Therapeutics, Inc. TREATMENT METHODS OF NEURO-EPITHELIAL TUMORS USING SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS
WO2022130015A2 (en) 2020-12-18 2022-06-23 Instil Bio (Uk) Limited Processing of tumor infiltrating lymphocytes

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2566779B2 (fr) * 1984-06-29 1987-03-06 Roussel Uclaf Nouveaux derives steroides substitues en 11b, leur procede de preparation et leur application comme medicaments
FR2596395B1 (fr) * 1986-03-26 1989-05-26 Roussel Uclaf Nouveaux steroides comportant un cycle spirannique en position 17, leur procede de preparation, leur application comme medicaments et les compositions les renfermant
DE3619413C2 (de) * 1986-06-10 2000-04-06 Schering Ag 9alpha, 10alpha-Methylen-Estrene, deren Herstellung und diese enthaltende pharmazeutische Präparate
FR2620707B1 (fr) * 1987-09-18 1989-12-08 Roussel Uclaf Nouveaux steroides comportant un cycle spirannique a 3, 4 ou 6 chainons en position 17, leur procede et des intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant

Also Published As

Publication number Publication date
EP0414606A2 (fr) 1991-02-27
AU6118990A (en) 1991-02-28
CN1033808C (zh) 1997-01-15
IE903031A1 (en) 1991-02-27
KR910004655A (ko) 1991-03-29
EP0414606A3 (en) 1991-07-24
IL95451A0 (en) 1991-06-30
US5166146A (en) 1992-11-24
HU208154B (en) 1993-08-30
DE69013815D1 (de) 1994-12-08
JP3026997B2 (ja) 2000-03-27
AU634569B2 (en) 1993-02-25
FR2651233A1 (fr) 1991-03-01
DE69013815T2 (de) 1995-03-16
HUT54706A (en) 1991-03-28
JPH0390097A (ja) 1991-04-16
PT95066A (pt) 1991-04-18
PT95066B (pt) 1997-05-28
ATE113605T1 (de) 1994-11-15
IE65922B1 (en) 1995-11-29
IL95451A (en) 1995-07-31
MX22020A (es) 1993-11-01
ZA906341B (en) 1991-10-30
EP0414606B1 (fr) 1994-11-02
RU2041236C1 (ru) 1995-08-09
HU905275D0 (en) 1991-02-28
CN1051362A (zh) 1991-05-15
ES2063313T3 (es) 1995-01-01
FR2651233B1 (fr) 1991-12-13
CA2022648A1 (fr) 1991-02-24

Similar Documents

Publication Publication Date Title
PT93502A (pt) Processo para a preparacao de novos derivados de insulina e de composicoes farmaceuticas que os contem
DK0414606T3 (da) Omega-Phenylaminoalkansyrer, som i den aromatiske ring er substitueret med en gruppe afledt af 19-nor-steroider, deres salte, en fremgangsmåde til deres fremstilling og mellemprodukter ved denne fremgangsmåde, deres anvendelse som lægemidler og præparater med indhold deraf
ES8705038A1 (es) Un procedimiento para preparar azatricicloalquenos.
ES2005059A4 (es) Nuevo procedimiento de preparacion de fibratos.
EA199900474A1 (ru) Предупреждение потери и восстановление костной массы некоторыми агонистами простагландина
ES8604565A1 (es) Un derivado de acido 6-fluor-1, 4-dihidro-4-oxo-7-piperazinil-quinolin sustituido-3-carboxilico
DE3260262D1 (en) (2-oxo-3-tetrahydrothienylcarbamoyl)-alkylthio acids, their salts and esters, their preparation and pharmaceutical compositions containing them
EP0090978A3 (en) Imidazolylphenyl-tetrahydropyridazines, process for their preparation and pharmaceutical compositions containing them
PT84424B (pt) Processo para a preparacao de derivados de heteroaril-oxi-beta-carbolina e de composicoes farmaceuticas que os contem
DK629889D0 (da) Aminosyrederivater, deres fremstilling og anvendelse som laegemidler
ES8401068A1 (es) Procedimiento para la preparacion de derivados de corinanteina, asi como de sus sales de adicion acida fisiologicamente inocuas.
EP0134179A3 (en) Derivatives of 4-phenyl-4-oxo-buten-2-oic acid, their preparation, their use as medicines and compositions containing them
DK152048C (da) Analogifremgangsmaade til fremstilling af n-substituerede tetrahydropyridinylindolderivater eller farmaceutisk acceptable salte deraf.
PT84074B (pt) Processo para a preparacao de derivados aminoglicosidicos do acido nor-colanico
DK0424504T3 (da) Nye 9alfa-hydroxy-3-oxo-4,24(25)-stigmastadien-26-syrederivater, fremgangsmåde til fremstilling deraf samt farmaceutiske præparater med indhold deraf
HUT47398A (en) Antiparasitic compositions comprising 2,2-dimethyl-cyclopropanecarboxylic acid derivatives and process for producing the active ingredients and their intermediates
DK61785A (da) 2-alkoxyaminosulfonylbenzensulfonylurinstofderivater, deres fremstilling og anvendelse som herbicider
FI832522A0 (fi) Foerfarande foer framstaellning av nya cefalosporinderivat, anvaendbara som antibiotika
GR3000773T3 (en) 2,2;6,6-diethylene-3-oxo-17-alpha-pregn-4-ene-21,17-carbolactones, process for their preparation and pharmaceutical compositions containing them
DK222087D0 (da) Aeny fremgangsmaade til fremstilling af kemiske for-bindelserae
DK0424248T3 (da) 20,21-dinoreburnamein med substitution i 15-stillingen, fremgangsmåde til deres fremstilling samt mellemprodukter til brug derved, deres anvendelse som lægemidler og præparater med indhold deraf
DK533583A (da) Steroidestere af n-(2-halogenethyl)-n-nitroso-carbamoyl-aminosyrer og deres peptider, samt fremgangsmaade til deres fremstilling
DE3469527D1 (en) Nortropine derivative, process for its preparation and its use
BR9306695A (pt) Processo para a preparação de um composto e uso do composto
DK523482A (da) Oximer af 3'''-dehydro-kardenolid-tridigitoxosider, fremgangsmaade til deres fremstilling og deres anvendelse som laegemiddel