ZA906341B - Omega-phenylamino alkanoic acids substituted on the aromatic nucleus by a radical derived from 19-nor steroids,their salts,their preparation process and the intermediates of this process,their use as medicaments and the compositions containing them - Google Patents
Omega-phenylamino alkanoic acids substituted on the aromatic nucleus by a radical derived from 19-nor steroids,their salts,their preparation process and the intermediates of this process,their use as medicaments and the compositions containing themInfo
- Publication number
- ZA906341B ZA906341B ZA906341A ZA906341A ZA906341B ZA 906341 B ZA906341 B ZA 906341B ZA 906341 A ZA906341 A ZA 906341A ZA 906341 A ZA906341 A ZA 906341A ZA 906341 B ZA906341 B ZA 906341B
- Authority
- ZA
- South Africa
- Prior art keywords
- denotes
- salts
- phenylamino
- steroids
- omega
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/42—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of mineralocorticosteroids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8911173A FR2651233B1 (fr) | 1989-08-23 | 1989-08-23 | Nouveaux acides omega-phenylamino alcanouiques substitues sur le noyau aromatique par un radical derive de 19-norsterouides, leur procede de preparation, leur application a titre de medicaments et les compositions les renfermant. |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA906341B true ZA906341B (en) | 1991-10-30 |
Family
ID=9384880
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA906341A ZA906341B (en) | 1989-08-23 | 1990-08-10 | Omega-phenylamino alkanoic acids substituted on the aromatic nucleus by a radical derived from 19-nor steroids,their salts,their preparation process and the intermediates of this process,their use as medicaments and the compositions containing them |
Country Status (19)
Country | Link |
---|---|
US (1) | US5166146A (pt) |
EP (1) | EP0414606B1 (pt) |
JP (1) | JP3026997B2 (pt) |
KR (1) | KR910004655A (pt) |
CN (1) | CN1033808C (pt) |
AT (1) | ATE113605T1 (pt) |
AU (1) | AU634569B2 (pt) |
CA (1) | CA2022648A1 (pt) |
DE (1) | DE69013815T2 (pt) |
DK (1) | DK0414606T3 (pt) |
ES (1) | ES2063313T3 (pt) |
FR (1) | FR2651233B1 (pt) |
HU (1) | HU208154B (pt) |
IE (1) | IE65922B1 (pt) |
IL (1) | IL95451A (pt) |
MX (1) | MX22020A (pt) |
PT (1) | PT95066B (pt) |
RU (1) | RU2041236C1 (pt) |
ZA (1) | ZA906341B (pt) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5780220A (en) * | 1994-05-19 | 1998-07-14 | Trustees Of The University Of Pennsylvania | Methods and compositions for inhibiting HIV replication |
US5639598A (en) * | 1994-05-19 | 1997-06-17 | The Trustees Of The University Of Pennsylvania | Method and kit for identification of antiviral agents capable of abrogating HIV Vpr-Rip-1 binding interactions |
US6090798A (en) * | 1997-12-19 | 2000-07-18 | Alcon Laboratories, Inc. | Treatment of GLC1A glaucoma with glucocorticoid antagonists |
ES2762243T3 (es) | 2010-05-26 | 2020-05-22 | Corcept Therapeutics Inc | Tratamiento de distrofia muscular |
EP3265127B1 (en) | 2015-03-02 | 2024-02-21 | Corcept Therapeutics, Inc. | Mifepristone and octreotide for use in the treatment of cushing's syndrome in a patient having an adrenocorticotropic hormone (acth)-secreting pancreatic neuroendocrine tumor |
WO2016160969A1 (en) | 2015-03-30 | 2016-10-06 | Corcept Therapeutics, Inc. | Use of glucocorticoid receptor antagonists in combination with glucocorticoids to treat adrenal insufficiency |
JP6768789B2 (ja) | 2015-08-13 | 2020-10-14 | コーセプト セラピューティクス, インコーポレイテッド | Acth依存性クッシング症候群を鑑別診断する方法 |
EP3405101B1 (en) | 2016-01-19 | 2020-12-23 | Corcept Therapeutics, Inc. | Differential diagnosis of ectopic cushing's syndrome |
US20180148471A1 (en) | 2016-11-30 | 2018-05-31 | Arno Therapeutics, Inc. | Methods for onapristone synthesis dehydration and deprotection |
US10413540B2 (en) | 2017-03-31 | 2019-09-17 | Corcept Therapeutics, Inc. | Glucocorticoid receptor modulators to treat cervical cancer |
EP3641780A4 (en) | 2017-06-20 | 2021-02-24 | Corcept Therapeutics, Inc. | TREATMENT METHODS OF NEURO-EPITHELIAL TUMORS USING SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS |
JP2024500748A (ja) | 2020-12-18 | 2024-01-10 | インスティル バイオ (ユーケイ) リミテッド | 腫瘍浸潤リンパ球の処理 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2566779B2 (fr) * | 1984-06-29 | 1987-03-06 | Roussel Uclaf | Nouveaux derives steroides substitues en 11b, leur procede de preparation et leur application comme medicaments |
FR2596395B1 (fr) * | 1986-03-26 | 1989-05-26 | Roussel Uclaf | Nouveaux steroides comportant un cycle spirannique en position 17, leur procede de preparation, leur application comme medicaments et les compositions les renfermant |
DE3619413C2 (de) * | 1986-06-10 | 2000-04-06 | Schering Ag | 9alpha, 10alpha-Methylen-Estrene, deren Herstellung und diese enthaltende pharmazeutische Präparate |
FR2620707B1 (fr) * | 1987-09-18 | 1989-12-08 | Roussel Uclaf | Nouveaux steroides comportant un cycle spirannique a 3, 4 ou 6 chainons en position 17, leur procede et des intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant |
-
1989
- 1989-08-23 FR FR8911173A patent/FR2651233B1/fr not_active Expired - Fee Related
-
1990
- 1990-08-03 CA CA002022648A patent/CA2022648A1/fr not_active Abandoned
- 1990-08-10 ZA ZA906341A patent/ZA906341B/xx unknown
- 1990-08-16 US US07/568,597 patent/US5166146A/en not_active Expired - Lifetime
- 1990-08-20 MX MX2202090A patent/MX22020A/es unknown
- 1990-08-20 JP JP02217281A patent/JP3026997B2/ja not_active Expired - Lifetime
- 1990-08-21 IL IL9545190A patent/IL95451A/en not_active IP Right Cessation
- 1990-08-22 ES ES90402328T patent/ES2063313T3/es not_active Expired - Lifetime
- 1990-08-22 IE IE303190A patent/IE65922B1/en not_active IP Right Cessation
- 1990-08-22 HU HU905275A patent/HU208154B/hu not_active IP Right Cessation
- 1990-08-22 PT PT95066A patent/PT95066B/pt not_active IP Right Cessation
- 1990-08-22 DK DK90402328.0T patent/DK0414606T3/da active
- 1990-08-22 DE DE69013815T patent/DE69013815T2/de not_active Expired - Lifetime
- 1990-08-22 AU AU61189/90A patent/AU634569B2/en not_active Ceased
- 1990-08-22 KR KR1019900012958A patent/KR910004655A/ko active IP Right Grant
- 1990-08-22 EP EP90402328A patent/EP0414606B1/fr not_active Expired - Lifetime
- 1990-08-22 AT AT90402328T patent/ATE113605T1/de not_active IP Right Cessation
- 1990-08-23 CN CN90107161A patent/CN1033808C/zh not_active Expired - Fee Related
-
1992
- 1992-05-18 RU SU925011511A patent/RU2041236C1/ru active
Also Published As
Publication number | Publication date |
---|---|
DE69013815T2 (de) | 1995-03-16 |
FR2651233A1 (fr) | 1991-03-01 |
HU905275D0 (en) | 1991-02-28 |
AU634569B2 (en) | 1993-02-25 |
RU2041236C1 (ru) | 1995-08-09 |
IE903031A1 (en) | 1991-02-27 |
IL95451A (en) | 1995-07-31 |
DK0414606T3 (da) | 1995-02-27 |
CN1051362A (zh) | 1991-05-15 |
CA2022648A1 (fr) | 1991-02-24 |
KR910004655A (ko) | 1991-03-29 |
PT95066A (pt) | 1991-04-18 |
CN1033808C (zh) | 1997-01-15 |
EP0414606A3 (en) | 1991-07-24 |
ES2063313T3 (es) | 1995-01-01 |
IE65922B1 (en) | 1995-11-29 |
PT95066B (pt) | 1997-05-28 |
IL95451A0 (en) | 1991-06-30 |
HUT54706A (en) | 1991-03-28 |
EP0414606A2 (fr) | 1991-02-27 |
US5166146A (en) | 1992-11-24 |
ATE113605T1 (de) | 1994-11-15 |
FR2651233B1 (fr) | 1991-12-13 |
MX22020A (es) | 1993-11-01 |
AU6118990A (en) | 1991-02-28 |
DE69013815D1 (de) | 1994-12-08 |
JPH0390097A (ja) | 1991-04-16 |
EP0414606B1 (fr) | 1994-11-02 |
HU208154B (en) | 1993-08-30 |
JP3026997B2 (ja) | 2000-03-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ZA906341B (en) | Omega-phenylamino alkanoic acids substituted on the aromatic nucleus by a radical derived from 19-nor steroids,their salts,their preparation process and the intermediates of this process,their use as medicaments and the compositions containing them | |
ES8502129A1 (es) | Un procedimiento para la preparacion de compuestos de acidos biliares | |
DE3260262D1 (en) | (2-oxo-3-tetrahydrothienylcarbamoyl)-alkylthio acids, their salts and esters, their preparation and pharmaceutical compositions containing them | |
ZA882595B (en) | Derivatives of 1,2,5,6-tetrahydropyridine,the process for preparing them,their use as medicaments and the compositions containing them | |
IL75206A (en) | Estriol 3,17beta-diesters,process for the preparation thereof and pharmaceutical compositions containing the same | |
IL72682A0 (en) | New derivatives of 4-phenyl-4-oxo-buten-2-oic acid,the process for preparing them,their application as medicaments and the compositions containing them | |
ES8307716A1 (es) | Procedimiento para la preparacion de bis-betainas. | |
ES8607986A1 (es) | Derivados de androsteno nuevos | |
IL110530A0 (en) | 15, 15-Dialkyl-substituted derivatives of estradiol and pharmaceutical compositions thereof | |
ATE104313T1 (de) | Neue 9-g(a)-hydroxy-3-oxo-4,24(25)-stigmastadien26-s|urederivate,verfahren zur herstellung und heilmittel daraus. | |
ES8801805A1 (es) | Procedimiento para la obtencion de nuevos derivados de isoxazol | |
DE3060096D1 (en) | 16-alpha-alkyl steroids, process for their preparation and pharmaceutical compositions containing them | |
JPS57149341A (en) | Colorant for polyolefin | |
ES8504187A1 (es) | Procedimiento para la preparacion de nuevos derivados de acidos apovincaminicos racemicos y opticamente activos, y de sus sales de adicion acidas | |
DE3361150D1 (en) | Steroid esters of n-(2-halogen-ethyl)-n-nitroso-carbamoyl amino acids and their peptides, and process for their preparation | |
GR3000773T3 (en) | 2,2;6,6-diethylene-3-oxo-17-alpha-pregn-4-ene-21,17-carbolactones, process for their preparation and pharmaceutical compositions containing them | |
ES8206468A1 (es) | Procedimiento de preparacion de derivados del acido 2-pirrol-acetico. | |
CA2008638A1 (fr) | Procede de preparation de tensio-actifs non-ioniques a partir de l'isopropyliene-1,2 epoxypropyl-3 glycrol et d'un acide carboxylique, nouveaux tensio-actifs non-ioniques et leur utilisation | |
EP0345719A3 (en) | Compounds containing at least three functional ester groups, and process for their preparation | |
GB1114584A (en) | 13-alkyl gonane esters |