DK0409676T3 - Acetylcholinesterase-inhibitorer - Google Patents

Acetylcholinesterase-inhibitorer

Info

Publication number
DK0409676T3
DK0409676T3 DK90401745.6T DK90401745T DK0409676T3 DK 0409676 T3 DK0409676 T3 DK 0409676T3 DK 90401745 T DK90401745 T DK 90401745T DK 0409676 T3 DK0409676 T3 DK 0409676T3
Authority
DK
Denmark
Prior art keywords
acetylcholinesterase inhibitors
acetylcholinesterase
inhibitors
Prior art date
Application number
DK90401745.6T
Other languages
Danish (da)
English (en)
Inventor
Daniel Schirlin
Jean-Noel Collard
Jean-Marie Hornsperger
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Application granted granted Critical
Publication of DK0409676T3 publication Critical patent/DK0409676T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/0803Compounds with Si-C or Si-Si linkages
    • C07F7/081Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
DK90401745.6T 1989-06-22 1990-06-20 Acetylcholinesterase-inhibitorer DK0409676T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP89401775A EP0403713A1 (en) 1989-06-22 1989-06-22 Novel acetylcholinesterase inhibitors

Publications (1)

Publication Number Publication Date
DK0409676T3 true DK0409676T3 (da) 1995-03-27

Family

ID=8202963

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90401745.6T DK0409676T3 (da) 1989-06-22 1990-06-20 Acetylcholinesterase-inhibitorer

Country Status (19)

Country Link
EP (2) EP0403713A1 (ja)
JP (1) JP2879951B2 (ja)
KR (1) KR0139529B1 (ja)
CN (1) CN1027759C (ja)
AR (1) AR247214A1 (ja)
AT (1) ATE119535T1 (ja)
AU (1) AU626428B2 (ja)
CA (1) CA2019231C (ja)
DE (1) DE69017543T2 (ja)
DK (1) DK0409676T3 (ja)
ES (1) ES2072406T3 (ja)
FI (1) FI97619C (ja)
HU (1) HU210569B (ja)
IE (1) IE66155B1 (ja)
IL (1) IL94779A (ja)
NO (1) NO178374C (ja)
NZ (1) NZ234136A (ja)
PT (1) PT94449B (ja)
ZA (1) ZA904715B (ja)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0611769A1 (en) * 1993-02-16 1994-08-24 Merrell Dow Pharmaceuticals Inc. Silylated acetylcholinesterase inhibitors
US5523442A (en) * 1993-02-16 1996-06-04 Merrell Pharmaceuticals Inc. Silylated acetylcholinesterase inhibitors
EP0627400A1 (en) * 1993-06-04 1994-12-07 Merrell Dow Pharmaceuticals Inc. Aromatic acetylcholinesterase inhibitors
US5554780A (en) * 1994-05-05 1996-09-10 Merrell Pharmaceuticals Inc. Process for the preparation of 1-(3-trialkylsilylphenyl)-2,2,2-trifluoromethyl ethanone derivatives
US5486638A (en) * 1994-11-08 1996-01-23 Marion Merrell Dow Inc. Process for the preparation of 1-halo-3-trialkysilanyl-benzene derivatives
EP0749972A1 (en) * 1995-06-21 1996-12-27 Merrell Pharmaceuticals Inc. A process for preparing 1-(3-trialkylsilylphenyl)-2,2,2-trifluoromethyl ethanone derivatives
US6673784B1 (en) 1996-03-19 2004-01-06 G. D. Searle & Co. Electrophilic ketones for the treatment of herpesvirus infections
CN1059702C (zh) * 1997-12-30 2000-12-20 中国科学院上海细胞生物学研究所 从哺乳类细胞中获得脑型乙酰胆碱酯酶的方法
US6218383B1 (en) 1998-08-07 2001-04-17 Targacept, Inc. Pharmaceutical compositions for the prevention and treatment of central nervous system disorders
US6084117A (en) * 1999-11-22 2000-07-04 Albemarle Corporation Production of silated haloarenes by selective silylation of polyhaloarenes
JP6082250B2 (ja) 2010-02-09 2017-02-15 ザ・ジョンズ・ホプキンス・ユニバーシティー 認知機能を改善するための方法および組成物
CA2891122C (en) 2012-11-14 2021-07-20 The Johns Hopkins University Methods and compositions for treating schizophrenia
ES2663680T3 (es) 2012-12-13 2018-04-16 H. Lundbeck A/S Composiciones que comprenden vortioxetina y donepezilo
CN105142623A (zh) 2013-03-15 2015-12-09 艾吉因生物股份有限公司 用于改善认知功能的方法和组合物
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
NZ738682A (en) 2015-05-22 2022-01-28 Agenebio Inc Extended release pharmaceutical compositions of levetiracetam

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL25820A (en) * 1966-05-22 1971-02-25 Yissum Res Dev Co Silicon containing beta-hydroxy alpha-phenyl carboxylic acids,their amide and ester derivatives and intermediates for their preparation
US4835099A (en) * 1986-11-20 1989-05-30 Becton, Dickinson And Company Signal enhancement in immunoassay by modulation of enzymatic catalysis

Also Published As

Publication number Publication date
DE69017543T2 (de) 1995-07-06
PT94449A (pt) 1991-02-08
NZ234136A (en) 1994-04-27
CA2019231C (en) 2000-07-11
EP0403713A1 (en) 1990-12-27
FI903104A0 (fi) 1990-06-20
ATE119535T1 (de) 1995-03-15
IL94779A (en) 1996-09-12
EP0409676B1 (en) 1995-03-08
IE66155B1 (en) 1995-12-13
JPH0338591A (ja) 1991-02-19
HU210569B (en) 1995-05-29
NO902776D0 (no) 1990-06-21
HU903933D0 (en) 1990-11-28
NO178374C (no) 1996-03-13
AU5758490A (en) 1991-01-03
ZA904715B (en) 1991-04-24
PT94449B (pt) 1997-02-28
FI97619B (fi) 1996-10-15
KR0139529B1 (ko) 1998-07-01
JP2879951B2 (ja) 1999-04-05
IE902252L (en) 1990-12-22
NO902776L (no) 1990-12-27
CA2019231A1 (en) 1990-12-22
CN1027759C (zh) 1995-03-01
IE902252A1 (en) 1991-01-16
CN1048389A (zh) 1991-01-09
KR910000757A (ko) 1991-01-30
HUT54695A (en) 1991-03-28
DE69017543D1 (de) 1995-04-13
ES2072406T3 (es) 1995-07-16
EP0409676A1 (en) 1991-01-23
FI97619C (fi) 1997-01-27
AU626428B2 (en) 1992-07-30
AR247214A1 (es) 1994-11-30
NO178374B (no) 1995-12-04

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