DK0397269T3 - Fremgangsmåde til syntese af ribonukleinsyre (RNA) - Google Patents

Fremgangsmåde til syntese af ribonukleinsyre (RNA)

Info

Publication number
DK0397269T3
DK0397269T3 DK90201162.6T DK90201162T DK0397269T3 DK 0397269 T3 DK0397269 T3 DK 0397269T3 DK 90201162 T DK90201162 T DK 90201162T DK 0397269 T3 DK0397269 T3 DK 0397269T3
Authority
DK
Denmark
Prior art keywords
synthesis
ribonucleic acid
rna
target sequence
sequence
Prior art date
Application number
DK90201162.6T
Other languages
English (en)
Inventor
Lawrence T Malek
Cheryl Davey
Peter Franklin Lens
Frits Wielaard
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Application granted granted Critical
Publication of DK0397269T3 publication Critical patent/DK0397269T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/705—Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
DK90201162.6T 1989-05-10 1990-05-08 Fremgangsmåde til syntese af ribonukleinsyre (RNA) DK0397269T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8901172 1989-05-10

Publications (1)

Publication Number Publication Date
DK0397269T3 true DK0397269T3 (da) 1995-05-29

Family

ID=19854626

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90201162.6T DK0397269T3 (da) 1989-05-10 1990-05-08 Fremgangsmåde til syntese af ribonukleinsyre (RNA)

Country Status (13)

Country Link
US (1) US5466586A (da)
EP (1) EP0397269B1 (da)
JP (1) JP2839639B2 (da)
KR (1) KR0185376B1 (da)
AT (1) ATE118549T1 (da)
AU (1) AU641159B2 (da)
CA (1) CA2016358C (da)
DE (1) DE69016826T2 (da)
DK (1) DK0397269T3 (da)
ES (1) ES2070995T3 (da)
FI (1) FI102387B (da)
IE (1) IE66597B1 (da)
ZA (1) ZA903453B (da)

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JPH08500722A (ja) * 1992-01-29 1996-01-30 日立化成工業株式会社 ポリヌクレオチド固定化担体
CA2135073C (en) * 1992-05-06 2002-11-19 Daniel L. Kacian Nucleic acid sequence amplification method, composition and kit
MX9300494A (es) * 1992-07-28 1994-07-29 Hitachi Chemical Co Ltd Metodo para la deteccion genetica de organismos, agentes infecciosos o componentes de una celula u organismo en una muestra biologica.
US5712127A (en) * 1996-04-29 1998-01-27 Genescape Inc. Subtractive amplification
DE19633427C2 (de) * 1996-08-20 2001-10-04 Hubert S Bernauer Verfahren zur Synthese von Nukleinsäuremolekülen mit zumindest teilweise vorbestimmter Nukleotidsequenz
DE19812103A1 (de) * 1998-03-19 1999-09-23 Bernauer Annette Verfahren zur Synthese von Nucleinsäuremolekülen
KR20030088035A (ko) * 2001-03-07 2003-11-15 바이오메리욱스 비.브이. 전사 기초한 증폭을 이용하는 ｄｎａ의 증폭 및 검출 방법
US20060051740A1 (en) 2001-03-07 2006-03-09 Deiman Birgit Alberta L M Method for the amplification and detection of hbv dna using a transcription based amplification
US8137911B2 (en) * 2001-05-22 2012-03-20 Cellscript, Inc. Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences
US7838270B2 (en) * 2001-05-22 2010-11-23 The University Of Chicago Target-dependent transcription using deletion mutants of N4 RNA polymerase
US7504215B2 (en) 2002-07-12 2009-03-17 Affymetrix, Inc. Nucleic acid labeling methods
US20050003369A1 (en) * 2002-10-10 2005-01-06 Affymetrix, Inc. Method for depleting specific nucleic acids from a mixture
US20040197802A1 (en) * 2002-11-21 2004-10-07 Dahl Gary A. Methods for using primers that encode one strand of a double-stranded promoter
US7266295B2 (en) * 2003-04-17 2007-09-04 Intel Corporation Modular reconfigurable multi-server system and method for high-speed networking within photonic burst-switched network
US7713697B2 (en) * 2004-08-27 2010-05-11 Gen-Probe Incorporated Methods and kits for amplifying DNA
EP1975242B1 (en) 2004-08-27 2011-03-02 Gen-Probe Incorporated Single-primer nucleic acid amplification methods
EP1882036B1 (en) 2005-05-17 2012-02-15 Ozgene Pty Ltd Sequential cloning system
US8293684B2 (en) * 2006-11-29 2012-10-23 Exiqon Locked nucleic acid reagents for labelling nucleic acids
US8183359B2 (en) * 2007-03-01 2012-05-22 Gen-Probe Incorporated Kits for amplifying DNA
WO2009006438A2 (en) 2007-06-29 2009-01-08 Epicentre Technologies Corporation Copy dna and sense rna
WO2010126913A1 (en) 2009-04-27 2010-11-04 Gen-Probe Incorporated Methods and kits for use in the selective amplification of target sequences
US9732337B2 (en) 2009-06-16 2017-08-15 The United Stated of America, as represented by the Secretary, Department of Health & Human Services RNA nanoparticles and nanotubes
TWI518325B (zh) 2010-02-04 2016-01-21 自治醫科大學 對ａｌｋ抑制劑具有先抗性或後抗性癌症的識別、判斷和治療
EP2600901B1 (en) 2010-08-06 2019-03-27 ModernaTX, Inc. A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof
ES2737960T3 (es) 2010-10-01 2020-01-17 Modernatx Inc Nucleósidos, nucleótidos y ácidos nucleicos modificados y sus usos
AU2012236099A1 (en) 2011-03-31 2013-10-03 Moderna Therapeutics, Inc. Delivery and formulation of engineered nucleic acids
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
EP3682905B1 (en) 2011-10-03 2021-12-01 ModernaTX, Inc. Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
FR2984357B1 (fr) 2011-12-16 2016-11-18 Biomerieux Sa Procede d'amplification transcriptionnelle d'acides nucleiques reunissant des etapes de temperatures differentes
EP2791160B1 (en) 2011-12-16 2022-03-02 ModernaTX, Inc. Modified mrna compositions
US9303079B2 (en) 2012-04-02 2016-04-05 Moderna Therapeutics, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
AU2013243948A1 (en) 2012-04-02 2014-10-30 Moderna Therapeutics, Inc. Modified polynucleotides for the production of proteins associated with human disease
EP4074834A1 (en) 2012-11-26 2022-10-19 ModernaTX, Inc. Terminally modified rna
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
WO2015006344A1 (en) * 2013-07-08 2015-01-15 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Method for synthesizing selectively labeled rna
KR20230074639A (ko) 2013-08-28 2023-05-30 벡톤 디킨슨 앤드 컴퍼니 대량의 동시 단일 세포 분석
JP6669655B2 (ja) 2013-09-17 2020-03-18 ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ 多機能ｒｎａナノ粒子及び使用方法
WO2015048744A2 (en) 2013-09-30 2015-04-02 Moderna Therapeutics, Inc. Polynucleotides encoding immune modulating polypeptides
CA2926218A1 (en) 2013-10-03 2015-04-09 Moderna Therapeutics, Inc. Polynucleotides encoding low density lipoprotein receptor
JP2016539639A (ja) 2013-11-13 2016-12-22 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル キッシング複合体を形成することができる核酸を含むキットオブパーツ及びその使用
WO2015171827A1 (en) 2014-05-06 2015-11-12 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Triggering rna interference with rna-dna and dna-rna nanoparticles
WO2018187373A1 (en) 2017-04-03 2018-10-11 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Functionally-interdependent shape switching nucleic acid nanoparticles

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US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4766072A (en) * 1985-07-17 1988-08-23 Promega Corporation Vectors for in vitro production of RNA copies of either strand of a cloned DNA sequence
IL86724A (en) * 1987-06-19 1995-01-24 Siska Diagnostics Inc Methods and kits for amplification and testing of nucleic acid sequences
EP0359789B1 (en) * 1988-01-21 1993-08-04 Genentech, Inc. Amplification and detection of nucleic acid sequences
CA1340807C (en) * 1988-02-24 1999-11-02 Lawrence T. Malek Nucleic acid amplification process

Also Published As

Publication number Publication date
IE901624L (en) 1990-11-10
EP0397269A1 (en) 1990-11-14
CA2016358C (en) 2000-11-28
CA2016358A1 (en) 1990-11-10
KR0185376B1 (ko) 1999-04-01
FI102387B1 (fi) 1998-11-30
ATE118549T1 (de) 1995-03-15
JP2839639B2 (ja) 1998-12-16
AU5487790A (en) 1990-11-15
US5466586A (en) 1995-11-14
ZA903453B (en) 1991-02-27
DE69016826D1 (de) 1995-03-23
DE69016826T2 (de) 1995-06-08
FI902318A0 (fi) 1990-05-09
EP0397269B1 (en) 1995-02-15
FI102387B (fi) 1998-11-30
KR900018376A (ko) 1990-12-21
ES2070995T3 (es) 1995-06-16
JPH03180184A (ja) 1991-08-06
AU641159B2 (en) 1993-09-16
IE66597B1 (en) 1996-01-24

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