DK0390762T3 - Hidtil ukendte bronchospasmolytiske forbindelser og fremgangsmåde til fremstilling heraf - Google Patents

Hidtil ukendte bronchospasmolytiske forbindelser og fremgangsmåde til fremstilling heraf

Info

Publication number
DK0390762T3
DK0390762T3 DK90850112.5T DK90850112T DK0390762T3 DK 0390762 T3 DK0390762 T3 DK 0390762T3 DK 90850112 T DK90850112 T DK 90850112T DK 0390762 T3 DK0390762 T3 DK 0390762T3
Authority
DK
Denmark
Prior art keywords
preparation
new
methods
bronchospasmolytic
compounds
Prior art date
Application number
DK90850112.5T
Other languages
Danish (da)
English (en)
Inventor
Otto Agne Torsten Olsson
Kjell Ingvar Leopold Wetterlin
Peter Juhan Pedaja
Carl Bertil Waldeck
Leif Ake Svensson
Original Assignee
Draco Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Draco Ab filed Critical Draco Ab
Application granted granted Critical
Publication of DK0390762T3 publication Critical patent/DK0390762T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/60Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/58Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK90850112.5T 1989-03-28 1990-03-23 Hidtil ukendte bronchospasmolytiske forbindelser og fremgangsmåde til fremstilling heraf DK0390762T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8901060A SE8901060D0 (sv) 1989-03-28 1989-03-28 New compounds

Publications (1)

Publication Number Publication Date
DK0390762T3 true DK0390762T3 (da) 1994-05-24

Family

ID=20375454

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90850112.5T DK0390762T3 (da) 1989-03-28 1990-03-23 Hidtil ukendte bronchospasmolytiske forbindelser og fremgangsmåde til fremstilling heraf

Country Status (30)

Country Link
EP (1) EP0390762B1 (is)
JP (1) JPH02286650A (is)
KR (1) KR900014309A (is)
CN (1) CN1045968A (is)
AR (1) AR247197A1 (is)
AT (1) ATE100437T1 (is)
AU (1) AU618171B2 (is)
CA (1) CA2013114A1 (is)
CZ (1) CZ280747B6 (is)
DD (1) DD297805A5 (is)
DE (1) DE69006071T2 (is)
DK (1) DK0390762T3 (is)
EG (1) EG18954A (is)
ES (1) ES2062495T3 (is)
FI (1) FI901528A0 (is)
HK (1) HK123396A (is)
HR (1) HRP920765A2 (is)
HU (1) HUT58043A (is)
IE (1) IE64851B1 (is)
IL (1) IL93799A (is)
IS (1) IS1581B (is)
LT (1) LT3979B (is)
LV (1) LV10708B (is)
NO (1) NO172115C (is)
NZ (1) NZ232765A (is)
PL (1) PL163566B1 (is)
PT (1) PT93576B (is)
SE (1) SE8901060D0 (is)
YU (1) YU47508B (is)
ZA (1) ZA901716B (is)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6040344A (en) * 1996-11-11 2000-03-21 Sepracor Inc. Formoterol process
ZA994264B (en) 1998-07-01 2000-01-25 Warner Lambert Co Stereoisomers with high affinity for adrenergic receptors.
US7232837B2 (en) 1999-06-29 2007-06-19 Mcneil-Ppc, Inc. Stereoisomers with high affinity for adrenergic receptors
US6472563B1 (en) 2001-11-09 2002-10-29 Sepracor Inc. Formoterol tartrate process and polymorph
US7169907B2 (en) * 2002-03-01 2007-01-30 Roche Diagnostics Operations, Inc. Derivatives, immunogens, and antibodies for detecting ecstasy-class drugs
EP2348013A1 (en) * 2010-01-25 2011-07-27 Inke, S.A. Process for preparation of intermediates of arformoterol

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4072720A (en) * 1971-01-19 1978-02-07 Mobil Oil Corporation Production of alcohol
US3700692A (en) * 1971-06-04 1972-10-24 Colgate Palmolive Co 1-(4{40 -hydroxy-3{40 -(hydroxy methyl)-phenyl)-1-hydroxy-2-aralkylaminoethanes
GB1531718A (en) * 1974-11-20 1978-11-08 Pharmacia As Phenylethanolamines

Also Published As

Publication number Publication date
AU5067590A (en) 1990-10-04
HK123396A (en) 1996-07-19
PT93576A (pt) 1990-11-07
IS3567A7 (is) 1990-09-29
LV10708B (en) 1996-02-20
LT3979B (en) 1996-06-25
FI901528A0 (fi) 1990-03-27
IL93799A (en) 1994-12-29
NZ232765A (en) 1992-12-23
LV10708A (lv) 1995-06-20
NO172115C (no) 1993-06-09
LTIP1719A (en) 1995-07-25
CZ151890A3 (en) 1995-12-13
ATE100437T1 (de) 1994-02-15
CA2013114A1 (en) 1990-09-28
CN1045968A (zh) 1990-10-10
EP0390762B1 (en) 1994-01-19
PL163566B1 (pl) 1994-04-29
AU618171B2 (en) 1991-12-12
PT93576B (pt) 1996-03-29
NO172115B (no) 1993-03-01
YU47508B (sh) 1995-10-03
DD297805A5 (de) 1992-01-23
YU46490A (en) 1992-05-28
CZ280747B6 (cs) 1996-04-17
EG18954A (en) 1994-03-30
DE69006071T2 (de) 1994-05-19
JPH02286650A (ja) 1990-11-26
DE69006071D1 (de) 1994-03-03
ZA901716B (en) 1990-12-28
KR900014309A (ko) 1990-10-23
IE64851B1 (en) 1995-09-06
AR247197A1 (es) 1994-11-30
IE901104L (en) 1990-09-28
NO900982D0 (no) 1990-03-01
NO900982L (no) 1990-10-01
HUT58043A (en) 1992-01-28
HU901854D0 (en) 1990-08-28
IS1581B (is) 1996-03-01
EP0390762A1 (en) 1990-10-03
ES2062495T3 (es) 1994-12-16
HRP920765A2 (en) 1995-02-28
SE8901060D0 (sv) 1989-03-28

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