DE78642T1 - Radiopharmazeutische zubereitung auf grund von technetium-99m und reagenz zur herstellung derselben. - Google Patents

Radiopharmazeutische zubereitung auf grund von technetium-99m und reagenz zur herstellung derselben.

Info

Publication number
DE78642T1
DE78642T1 DE198282305639T DE82305639T DE78642T1 DE 78642 T1 DE78642 T1 DE 78642T1 DE 198282305639 T DE198282305639 T DE 198282305639T DE 82305639 T DE82305639 T DE 82305639T DE 78642 T1 DE78642 T1 DE 78642T1
Authority
DE
Germany
Prior art keywords
acid
composition
technetium
agent
reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE198282305639T
Other languages
German (de)
English (en)
Inventor
John Amersham Buckinghamshire Hp7 9Ll Rimmer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare Ltd
Original Assignee
Amersham International PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amersham International PLC filed Critical Amersham International PLC
Publication of DE78642T1 publication Critical patent/DE78642T1/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0489—Phosphates or phosphonates, e.g. bone-seeking phosphonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE198282305639T 1981-10-30 1982-10-22 Radiopharmazeutische zubereitung auf grund von technetium-99m und reagenz zur herstellung derselben. Pending DE78642T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8132778 1981-10-30

Publications (1)

Publication Number Publication Date
DE78642T1 true DE78642T1 (de) 1983-10-27

Family

ID=10525506

Family Applications (2)

Application Number Title Priority Date Filing Date
DE198282305639T Pending DE78642T1 (de) 1981-10-30 1982-10-22 Radiopharmazeutische zubereitung auf grund von technetium-99m und reagenz zur herstellung derselben.
DE8282305639T Expired DE3274621D1 (en) 1981-10-30 1982-10-22 Radiopharmaceutical composition based on technetium-99m and reagent for making it

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8282305639T Expired DE3274621D1 (en) 1981-10-30 1982-10-22 Radiopharmaceutical composition based on technetium-99m and reagent for making it

Country Status (8)

Country Link
US (1) US4451451A (OSRAM)
EP (1) EP0078642B1 (OSRAM)
JP (1) JPS5885823A (OSRAM)
AU (1) AU560024B2 (OSRAM)
CA (1) CA1190473A (OSRAM)
DE (2) DE78642T1 (OSRAM)
FI (1) FI78839C (OSRAM)
NO (1) NO159342C (OSRAM)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4707353A (en) * 1982-12-08 1987-11-17 Mallinckrodt, Inc. Radiographic imaging agents
DE3331159A1 (de) * 1983-08-30 1985-03-14 Hoechst Ag, 6230 Frankfurt N-(4-aminobenzoyl)-aminodicarbonsaeuren zur stabilisierung von technetium-99m-praeparaten, stabilisierte injektionspraeparate und verfahren zu ihrer herstellung
DE3577274D1 (de) * 1984-01-23 1990-05-31 Inst Energiteknik Zusammensetzung zur technetium-99m-markierung von proteinhaltigem material.
GB8510726D0 (en) * 1985-04-26 1985-06-26 Amersham Int Plc Stabilised radio-labelled compounds
DE3780820D1 (OSRAM) * 1987-10-30 1992-09-03 Sorin Biomedica S.P.A., Saluggia, Vercelli, It
US5306482A (en) * 1991-04-09 1994-04-26 Merck Frosst Canada, Inc. Radiopharmaceutical bacteriostats
US5686058A (en) * 1992-04-30 1997-11-11 Amersham International Plc Radiolabelled nucleotide formulations stored in an unfrozen state
CA2105402C (en) * 1992-04-30 2000-04-04 Roger M. Price Radiolabelled compound formulations
DE69617685T2 (de) * 1995-06-28 2002-06-13 Nen Life Science Products, Inc.(N.D.Ges.Des Staates Delaware) Zusammensetzung und verfahren zur stabilisierung von radiomarkierten organischen verbindungen
RU2132681C1 (ru) * 1998-10-21 1999-07-10 Севиндж Исмаил кызы Акберова Индуктор интерферона
GB0015242D0 (en) * 2000-06-22 2000-08-16 Nycomed Amersham Plc Stabiliser for radiopharmaceuticals
ATE445418T1 (de) * 2000-10-19 2009-10-15 Bracco Imaging Spa Radiopharmazeutische formulierungen
US6989138B2 (en) 2000-10-24 2006-01-24 Diatide, Inc. Stabilization of radiopharmaceutical compositions using hydrophilic thioethers and hydrophilic 6-hydroxy chromans
US6881396B2 (en) * 2000-10-24 2005-04-19 Diatide, Inc. Stabilization of radiopharmaceutical compositions using hydrophilic 6-hydroxy-chromans
US6902718B2 (en) * 2000-10-24 2005-06-07 Diatide, Inc. Stabilization of radiopharmaceutical compositions using hydrophilic thioethers
GB0031592D0 (en) * 2000-12-28 2001-02-07 Nycomed Amersham Plc Stabilised radiopharmaceutical compositions
CN100471523C (zh) * 2002-05-03 2009-03-25 伯拉考成像股份公司 放射性药物制剂
EP1444990A1 (en) * 2003-02-07 2004-08-11 Amersham plc Improved Radiometal Complex Compositions
SG177216A1 (en) * 2003-07-24 2012-01-30 Bracco Imaging Spa Stable radiopharmaceutical compositions and methods for their preparation
ES2804509T3 (es) 2010-07-27 2021-02-08 Serac Healthcare Ltd Composiciones radiofarmacéuticas
BR112013015580A2 (pt) * 2010-12-21 2016-10-04 Ge Healthcare Ltd método de radioestabilização
AU2018372768B2 (en) * 2017-11-23 2021-07-01 Jubilant Draximage Inc. Pharmaceutical composition comprising tetrofosmin and pharmaceutically acceptable salts thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4364920A (en) * 1975-04-30 1982-12-21 Medi-Physics, Inc. Stable diagnostic reagents
US4048296A (en) * 1975-05-27 1977-09-13 Mallinckrodt, Inc. Radiopharmaceutical scanning agents
US4042676A (en) * 1975-10-09 1977-08-16 Union Carbide Corporation Technetium-99m labeled radiodiagnostic agents for liver and bone marrow scanning and method of preparation
US4233284A (en) * 1978-03-31 1980-11-11 The Procter & Gamble Company Stabilized radiographic scanning agents
US4232000A (en) * 1978-06-28 1980-11-04 The Procter & Gamble Company Radioactive scanning agents with stabilizer
US4229427A (en) * 1978-06-28 1980-10-21 The Procter & Gamble Company Radioactive scanning agents with hydroquinone stabilizer
US4247534A (en) * 1978-07-31 1981-01-27 The Procter & Gamble Company Radiographic scanning agent

Also Published As

Publication number Publication date
AU8988882A (en) 1983-05-05
NO159342B (no) 1988-09-12
FI78839C (fi) 1989-10-10
EP0078642A2 (en) 1983-05-11
AU560024B2 (en) 1987-03-26
US4451451A (en) 1984-05-29
DE3274621D1 (en) 1987-01-22
NO159342C (no) 1988-12-21
EP0078642A3 (en) 1984-02-22
JPS6132291B2 (OSRAM) 1986-07-25
CA1190473A (en) 1985-07-16
FI823657L (fi) 1983-05-01
FI78839B (fi) 1989-06-30
JPS5885823A (ja) 1983-05-23
FI823657A0 (fi) 1982-10-26
NO823609L (no) 1983-05-02
EP0078642B1 (en) 1986-12-10

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