DE69941261D1 - Herstellung von il-10 in einen pflanzenbioreaktor aus pflanzen, die nicht zur ernährung verwendet werden - Google Patents

Herstellung von il-10 in einen pflanzenbioreaktor aus pflanzen, die nicht zur ernährung verwendet werden

Info

Publication number
DE69941261D1
DE69941261D1 DE69941261T DE69941261T DE69941261D1 DE 69941261 D1 DE69941261 D1 DE 69941261D1 DE 69941261 T DE69941261 T DE 69941261T DE 69941261 T DE69941261 T DE 69941261T DE 69941261 D1 DE69941261 D1 DE 69941261D1
Authority
DE
Germany
Prior art keywords
interest
crop plant
food crop
csf
oral administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69941261T
Other languages
English (en)
Inventor
Jim Brandle
Peter L Davies
Kimberley D Kenward
Rima Menassa
Tony Jevnikar
Terry Delovitch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Canada, As Re Ca
Original Assignee
Agriculture and Agri Food Canada AAFC
London Health Services Centre
Queens University at Kingston
London Health Sciences Centre Research Inc
John P Robarts Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agriculture and Agri Food Canada AAFC, London Health Services Centre, Queens University at Kingston, London Health Sciences Centre Research Inc, John P Robarts Research Institute filed Critical Agriculture and Agri Food Canada AAFC
Application granted granted Critical
Publication of DE69941261D1 publication Critical patent/DE69941261D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Nutrition Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Fertilizers (AREA)
DE69941261T 1998-06-22 1999-06-21 Herstellung von il-10 in einen pflanzenbioreaktor aus pflanzen, die nicht zur ernährung verwendet werden Expired - Lifetime DE69941261D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10205098A 1998-06-22 1998-06-22
PCT/CA1999/000577 WO1999067401A2 (en) 1998-06-22 1999-06-21 Non-food crop plant bioreactor

Publications (1)

Publication Number Publication Date
DE69941261D1 true DE69941261D1 (de) 2009-09-24

Family

ID=22287857

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69941261T Expired - Lifetime DE69941261D1 (de) 1998-06-22 1999-06-21 Herstellung von il-10 in einen pflanzenbioreaktor aus pflanzen, die nicht zur ernährung verwendet werden

Country Status (6)

Country Link
EP (1) EP1090133B8 (de)
AT (1) ATE439446T1 (de)
AU (1) AU4355099A (de)
DE (1) DE69941261D1 (de)
ES (1) ES2336861T3 (de)
WO (1) WO1999067401A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7361331B2 (en) * 1996-10-18 2008-04-22 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food Plant bioreactors
GB2364705A (en) * 2000-07-14 2002-02-06 Icgeb Fusion protein expression in plastids
US20050287647A9 (en) 2001-05-30 2005-12-29 Carl Perez Plant artificial chromosomes, uses thereof and methods of preparing plant artificial chromosomes
US7329798B2 (en) 2002-06-28 2008-02-12 University Of Guelph Harvest-inducible regulatory elements and methods of using same
WO2004002216A2 (en) 2002-06-28 2004-01-08 University Of Guelph Harvest-inducible genes from alfalfa (medicago sativa) and methods of use thereof
US7951557B2 (en) 2003-04-27 2011-05-31 Protalix Ltd. Human lysosomal proteins from plant cell culture
AU2012241058B2 (en) * 2005-07-18 2014-04-17 Protalix Ltd. Mucosal or Enteral Administration of Biologically Active Macromolecules
KR20080038131A (ko) * 2005-07-18 2008-05-02 프로탈릭스 리미티드 생물학적으로 활성인 거대분자의 점막 또는 장관 투여
US9194011B2 (en) 2009-11-17 2015-11-24 Protalix Ltd. Stabilized alpha-galactosidase and uses thereof
WO2012045334A1 (en) 2010-10-05 2012-04-12 Synthon Bv Biologically active il-10 fusion proteins
EP2809780B1 (de) 2012-02-01 2018-05-02 Protalix Ltd. Inhalierbare flüssige formulierungen der dnase i
US20160017021A1 (en) 2013-03-06 2016-01-21 Protalix Ltd. TNF alpha INHIBITOR POLYPEPTIDES, POLYNUCLEOTIDES ENCODING SAME, CELLS EXPRESSING SAME AND METHODS OF PRODUCING SAME
AU2014224174B2 (en) 2013-03-06 2018-08-30 Hadasit Medical Research Services And Development Ltd. Use of plant cells expressing a TNFalpha polypeptide inhibitor in therapy
US10000551B2 (en) 2014-09-11 2018-06-19 Protalix Ltd. Chimeric polypeptides, polynucleotides encoding same, cells expressing same and methods of producing same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0596979B1 (de) * 1991-08-01 2002-01-30 Large Scale Biology Corporation Rekombinierte virale nukleinsäure aus pflanzen
CA2188220A1 (en) * 1996-10-18 1998-04-18 Kimberley Kenward Non-food crop plant bioreactor

Also Published As

Publication number Publication date
AU4355099A (en) 2000-01-10
ATE439446T1 (de) 2009-08-15
ES2336861T3 (es) 2010-04-16
EP1090133A2 (de) 2001-04-11
EP1090133B8 (de) 2009-11-25
WO1999067401A2 (en) 1999-12-29
WO1999067401A3 (en) 2000-03-23
EP1090133B1 (de) 2009-08-12

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Owner name: HER MAJESTY THE QUEEN IN RIGHT OF CANADA AS RE, CA