DE69940848D1 - (-)-strang rns virusvektor für nervenzellen - Google Patents

(-)-strang rns virusvektor für nervenzellen

Info

Publication number
DE69940848D1
DE69940848D1 DE69940848T DE69940848T DE69940848D1 DE 69940848 D1 DE69940848 D1 DE 69940848D1 DE 69940848 T DE69940848 T DE 69940848T DE 69940848 T DE69940848 T DE 69940848T DE 69940848 D1 DE69940848 D1 DE 69940848D1
Authority
DE
Germany
Prior art keywords
nerve cells
virus vector
rna virus
string
string rna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69940848T
Other languages
English (en)
Inventor
Masayuki Fukumura
Makoto Asakawa
Mamoru Hasegawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dnavec Research Inc
Original Assignee
Dnavec Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dnavec Research Inc filed Critical Dnavec Research Inc
Application granted granted Critical
Publication of DE69940848D1 publication Critical patent/DE69940848D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01031Beta-glucuronidase (3.2.1.31)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/50Fibroblast growth factors [FGF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18811Sendai virus
    • C12N2760/18841Use of virus, viral particle or viral elements as a vector
    • C12N2760/18843Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18811Sendai virus
    • C12N2760/18871Demonstrated in vivo effect
DE69940848T 1998-07-03 1999-07-01 (-)-strang rns virusvektor für nervenzellen Expired - Lifetime DE69940848D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP20433398 1998-07-03
PCT/JP1999/003552 WO2000001837A1 (fr) 1998-07-03 1999-07-01 Vecteur de virus a arn a brin negatif

Publications (1)

Publication Number Publication Date
DE69940848D1 true DE69940848D1 (de) 2009-06-18

Family

ID=16488770

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69940848T Expired - Lifetime DE69940848D1 (de) 1998-07-03 1999-07-01 (-)-strang rns virusvektor für nervenzellen

Country Status (12)

Country Link
US (1) US20050158279A1 (de)
EP (1) EP1094115B1 (de)
JP (1) JP3883213B2 (de)
KR (1) KR20010074631A (de)
CN (1) CN1249248C (de)
AT (1) ATE430806T1 (de)
AU (1) AU4395599A (de)
CA (1) CA2336472C (de)
DE (1) DE69940848D1 (de)
ES (1) ES2326101T3 (de)
HK (1) HK1039792B (de)
WO (1) WO2000001837A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4791651B2 (ja) * 2000-05-18 2011-10-12 株式会社ディナベック研究所 外来遺伝子導入用パラミクソウイルスベクター
WO2002000264A1 (fr) * 2000-06-27 2002-01-03 Dnavec Research Inc. Vecteur de virus pour transfert de gene dans des cellules renales
CA2553377A1 (en) 2004-01-13 2005-07-28 Dnavec Research Inc. Gene therapy for tumors using minus-strand rna viral vectors encoding immunostimaulatory cytokines

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6015686A (en) * 1993-09-15 2000-01-18 Chiron Viagene, Inc. Eukaryotic layered vector initiation systems
US5824655A (en) * 1995-02-15 1998-10-20 The University Of Utah Anti-transforming growth factor-β gene therapy
KR100754091B1 (ko) * 1995-10-31 2007-08-31 가부시끼가이샤 디나벡 겡뀨쇼 자율 복제 능력을 갖는 (-)쇄 rna 바이러스 벡터
WO1997016539A1 (fr) * 1995-11-01 1997-05-09 Dnavec Research Inc. Virus sendai recombinant
EP1066395B1 (de) * 1998-03-27 2005-09-14 Cytos Biotechnology AG Induzierendes alphavirengen- expressionssystem
US6740524B1 (en) * 1998-06-18 2004-05-25 Dnavec Research, Inc. Nucleic acid transfer phage
EP1100545A4 (de) * 1998-07-29 2002-03-20 Invitrogen Corp Regulierte expression von rekombinanten proteinen unter verwendung von rns-viren
US6723938B1 (en) * 1999-03-22 2004-04-20 Peter Jon Gates Electrostatic conductive induction separator
JP3602058B2 (ja) * 1999-05-18 2004-12-15 株式会社ディナベック研究所 エンベロープ遺伝子欠損パラミクソ科ウイルスベクター
ATE393235T1 (de) * 2000-11-27 2008-05-15 Dnavec Research Inc Für fibroblasten-wachstumsfaktor 2 (fgf2) kodierender paramyxovirus-vektor und dessen verwendung

Also Published As

Publication number Publication date
ATE430806T1 (de) 2009-05-15
AU4395599A (en) 2000-01-24
HK1039792A1 (en) 2002-05-10
US20050158279A1 (en) 2005-07-21
EP1094115B1 (de) 2009-05-06
ES2326101T3 (es) 2009-09-30
CA2336472C (en) 2010-08-31
HK1039792B (zh) 2006-08-18
CN1314949A (zh) 2001-09-26
CN1249248C (zh) 2006-04-05
WO2000001837A1 (fr) 2000-01-13
EP1094115A4 (de) 2005-11-02
CA2336472A1 (en) 2000-01-13
JP3883213B2 (ja) 2007-02-21
KR20010074631A (ko) 2001-08-04
EP1094115A1 (de) 2001-04-25

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