HK1039792B - 用於神經細胞轉移基因的負鏈rna病毒載體 - Google Patents
用於神經細胞轉移基因的負鏈rna病毒載體Info
- Publication number
- HK1039792B HK1039792B HK02101038.0A HK02101038A HK1039792B HK 1039792 B HK1039792 B HK 1039792B HK 02101038 A HK02101038 A HK 02101038A HK 1039792 B HK1039792 B HK 1039792B
- Authority
- HK
- Hong Kong
- Prior art keywords
- negative
- rna virus
- sense rna
- vetor
- nerve cell
- Prior art date
Links
- 210000002569 neuron Anatomy 0.000 title abstract 3
- 241000700605 Viruses Species 0.000 title 1
- 241001493065 dsRNA viruses Species 0.000 abstract 1
- 238000001415 gene therapy Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000000944 nerve tissue Anatomy 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01031—Beta-glucuronidase (3.2.1.31)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18811—Sendai virus
- C12N2760/18841—Use of virus, viral particle or viral elements as a vector
- C12N2760/18843—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18811—Sendai virus
- C12N2760/18871—Demonstrated in vivo effect
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20433398 | 1998-07-03 | ||
| PCT/JP1999/003552 WO2000001837A1 (fr) | 1998-07-03 | 1999-07-01 | Vecteur de virus a arn a brin negatif |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HK1039792A1 HK1039792A1 (en) | 2002-05-10 |
| HK1039792B true HK1039792B (zh) | 2006-08-18 |
Family
ID=16488770
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK02101038.0A HK1039792B (zh) | 1998-07-03 | 2002-02-09 | 用於神經細胞轉移基因的負鏈rna病毒載體 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20050158279A1 (zh) |
| EP (1) | EP1094115B1 (zh) |
| JP (1) | JP3883213B2 (zh) |
| KR (1) | KR20010074631A (zh) |
| CN (1) | CN1249248C (zh) |
| AT (1) | ATE430806T1 (zh) |
| AU (1) | AU4395599A (zh) |
| CA (1) | CA2336472C (zh) |
| DE (1) | DE69940848D1 (zh) |
| ES (1) | ES2326101T3 (zh) |
| HK (1) | HK1039792B (zh) |
| WO (1) | WO2000001837A1 (zh) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4791651B2 (ja) * | 2000-05-18 | 2011-10-12 | 株式会社ディナベック研究所 | 外来遺伝子導入用パラミクソウイルスベクター |
| WO2002000264A1 (fr) * | 2000-06-27 | 2002-01-03 | Dnavec Research Inc. | Vecteur de virus pour transfert de gene dans des cellules renales |
| CN1929867A (zh) | 2004-01-13 | 2007-03-14 | 株式会社载体研究所 | 肿瘤的基因治疗，即利用编码免疫刺激性细胞因子的单链负链rna病毒载体进行的治疗 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6015686A (en) * | 1993-09-15 | 2000-01-18 | Chiron Viagene, Inc. | Eukaryotic layered vector initiation systems |
| US5824655A (en) * | 1995-02-15 | 1998-10-20 | The University Of Utah | Anti-transforming growth factor-β gene therapy |
| DK0864645T3 (da) * | 1995-10-31 | 2005-10-24 | Dnavec Research Inc | Negativstrenget RNA-virusvektor med autonom replikeringsaktivitet |
| KR100525687B1 (ko) * | 1995-11-01 | 2005-11-25 | 가부시끼가이샤 디나벡 겡뀨쇼 | 재조합체 센다이바이러스 |
| CA2325564A1 (en) * | 1998-03-27 | 1999-10-07 | Cytos Biotechnology Ag | Inducible alphaviral gene expression system |
| WO1999066061A1 (fr) * | 1998-06-18 | 1999-12-23 | Dnavec Research, Inc. | Phage de transfert d'acide nucleique |
| US6451579B1 (en) * | 1998-07-29 | 2002-09-17 | Invitrogen Corporation | Regulated expression of recombinant proteins using RNA viruses |
| US6723938B1 (en) * | 1999-03-22 | 2004-04-20 | Peter Jon Gates | Electrostatic conductive induction separator |
| DE60035589T2 (de) * | 1999-05-18 | 2008-04-17 | Dnavec Research Inc., Tsukuba | Viraler paramyxoviridae vektor mit einem defekten hüllprotein-gen |
| AU2002224113A1 (en) * | 2000-11-27 | 2002-06-03 | Dnavec Research Inc. | Paramyxovirus vector encoding angiogenesis gene and utilization thereof |
-
1999
- 1999-07-01 AT AT99926878T patent/ATE430806T1/de not_active IP Right Cessation
- 1999-07-01 DE DE69940848T patent/DE69940848D1/de not_active Expired - Lifetime
- 1999-07-01 ES ES99926878T patent/ES2326101T3/es not_active Expired - Lifetime
- 1999-07-01 CN CNB998102245A patent/CN1249248C/zh not_active Expired - Fee Related
- 1999-07-01 KR KR1020017000020A patent/KR20010074631A/ko not_active Application Discontinuation
- 1999-07-01 CA CA2336472A patent/CA2336472C/en not_active Expired - Fee Related
- 1999-07-01 WO PCT/JP1999/003552 patent/WO2000001837A1/ja not_active Application Discontinuation
- 1999-07-01 EP EP99926878A patent/EP1094115B1/en not_active Expired - Lifetime
- 1999-07-01 JP JP55151999A patent/JP3883213B2/ja not_active Expired - Fee Related
- 1999-07-01 AU AU43955/99A patent/AU4395599A/en not_active Abandoned
-
2002
- 2002-02-09 HK HK02101038.0A patent/HK1039792B/zh not_active IP Right Cessation
-
2004
- 2004-05-06 US US10/840,800 patent/US20050158279A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN1249248C (zh) | 2006-04-05 |
| HK1039792A1 (en) | 2002-05-10 |
| EP1094115B1 (en) | 2009-05-06 |
| CN1314949A (zh) | 2001-09-26 |
| US20050158279A1 (en) | 2005-07-21 |
| JP3883213B2 (ja) | 2007-02-21 |
| DE69940848D1 (de) | 2009-06-18 |
| CA2336472C (en) | 2010-08-31 |
| EP1094115A4 (en) | 2005-11-02 |
| ES2326101T3 (es) | 2009-09-30 |
| KR20010074631A (ko) | 2001-08-04 |
| AU4395599A (en) | 2000-01-24 |
| CA2336472A1 (en) | 2000-01-13 |
| ATE430806T1 (de) | 2009-05-15 |
| WO2000001837A1 (fr) | 2000-01-13 |
| EP1094115A1 (en) | 2001-04-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20110701 |