DE69937369T2 - CCR5 Antikörper PA14 - Google Patents

CCR5 Antikörper PA14 Download PDF

Info

Publication number
DE69937369T2
DE69937369T2 DE69937369T DE69937369T DE69937369T2 DE 69937369 T2 DE69937369 T2 DE 69937369T2 DE 69937369 T DE69937369 T DE 69937369T DE 69937369 T DE69937369 T DE 69937369T DE 69937369 T2 DE69937369 T2 DE 69937369T2
Authority
DE
Germany
Prior art keywords
ccr5
antibody
hiv
cells
mabs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69937369T
Other languages
German (de)
English (en)
Other versions
DE69937369D1 (de
Inventor
William C. Ossining OLSON
Paul J. Scarsdale Maddon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Progenics Pharmaceuticals Inc
Original Assignee
Progenics Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Progenics Pharmaceuticals Inc filed Critical Progenics Pharmaceuticals Inc
Application granted granted Critical
Publication of DE69937369D1 publication Critical patent/DE69937369D1/de
Publication of DE69937369T2 publication Critical patent/DE69937369T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69937369T 1998-12-16 1999-12-16 CCR5 Antikörper PA14 Expired - Lifetime DE69937369T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US21279398A 1998-12-16 1998-12-16
US11253298P 1998-12-16 1998-12-16
US212793 1998-12-16
PCT/US1999/030345 WO2000035409A2 (en) 1998-12-16 1999-12-16 Hiv-i fusion inhibition compounds
US112532P 2008-11-07

Publications (2)

Publication Number Publication Date
DE69937369D1 DE69937369D1 (de) 2007-11-29
DE69937369T2 true DE69937369T2 (de) 2008-07-24

Family

ID=26810060

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69937369T Expired - Lifetime DE69937369T2 (de) 1998-12-16 1999-12-16 CCR5 Antikörper PA14

Country Status (13)

Country Link
EP (2) EP1144006B1 (https=)
JP (1) JP2002538771A (https=)
AT (1) ATE375802T1 (https=)
AU (3) AU773175B2 (https=)
CA (1) CA2355607A1 (https=)
CY (1) CY1107858T1 (https=)
DE (1) DE69937369T2 (https=)
DK (1) DK1144006T3 (https=)
ES (1) ES2296416T3 (https=)
HK (1) HK1041207B (https=)
MX (1) MXPA01006097A (https=)
PT (1) PT1144006E (https=)
WO (1) WO2000035409A2 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0847452B1 (en) 1995-06-07 2009-04-01 Progenics Pharmaceuticals, Inc. Monoclonal antibody for inhibiting hiv-1 envelope glycoprotein mediated membrane fusion
US7118859B2 (en) 1996-01-17 2006-10-10 Progenics Pharmaceuticals, Inc. Methods for inhibiting HIV-1 infection
AU2265701A (en) * 1999-12-16 2001-06-25 Tanox, Inc. Anti-hiv-1 conjugates for treatment of hiv disease
US7138119B2 (en) 2000-09-15 2006-11-21 Progenics Pharmaceuticals, Inc. Compositions and methods for inhibition of HIV-1 infection
US7060273B2 (en) 2001-04-06 2006-06-13 Progenics Pharmaceuticals, Inc. Methods for inhibiting HIV-1 infection
US20020146415A1 (en) * 2001-04-06 2002-10-10 Olson William C. Methods for inhibiting HIV-1 infection
US20060078537A1 (en) * 2001-12-21 2006-04-13 Matthias Mack Mono-and dual chemokine/cytokine constructs
DE60324664D1 (de) * 2002-02-22 2008-12-24 Pdl Biopharma Inc Anti-ccr5 antikörper
US7122185B2 (en) 2002-02-22 2006-10-17 Progenics Pharmaceuticals, Inc. Anti-CCR5 antibody
TW200720289A (en) 2005-04-01 2007-06-01 Hoffmann La Roche Antibodies against CCR5 and uses thereof
JP2009525301A (ja) * 2006-01-30 2009-07-09 エフ．ホフマン−ラ ロシュ アーゲー Ｈｉｖを処置するための相乗的組成物
TW200817438A (en) 2006-08-17 2008-04-16 Hoffmann La Roche A conjugate of an antibody against CCR5 and an antifusogenic peptide
AU2007286451A1 (en) 2006-08-17 2008-02-21 F. Hoffmann-La Roche Ag A conjugate of an antibody against CCR5 and an antifusogenic peptide
KR20090052358A (ko) 2006-09-29 2009-05-25 에프. 호프만-라 로슈 아게 Ｃｃｒ5 에 대한 항체 및 이의 용도
CL2008000707A1 (es) 2007-03-13 2008-09-22 Hoffmann La Roche Conjugado de polipeptidos antifusogenicos y polipeptidos derivados de la cabeza globular del factor del complemento c1q; composicion farmaceutica que lo comprende; su uso para tratar infecciones viricas; y metodo de produccion.
EP2741777B1 (en) 2011-08-12 2017-01-18 INSERM - Institut National de la Santé et de la Recherche Médicale Methods and pharmaceutical compositions for treatment of pulmonary hypertension
US11629196B2 (en) 2020-04-27 2023-04-18 Incelldx, Inc. Method of treating SARS-CoV-2-associated hypercytokinemia by administering a human monoclonal antibody (PRO-140) that inhibits CCR5/CCL5 binding interactions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3375697A (en) * 1996-05-28 1998-01-05 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Cc chemokine receptor 5, antibodies thereto, transgenic animals
AU735460B2 (en) * 1996-06-14 2001-07-12 Aaron Diamond Aids Research Center, The Uses of a chemokine receptor for inhibiting HIV-1 infection
US6528625B1 (en) * 1996-10-28 2003-03-04 Millennium Pharmaceuticals, Inc. Anti-CCR5 antibodies and kits comprising same

Also Published As

Publication number Publication date
AU2004205165A1 (en) 2004-09-16
EP2088158A2 (en) 2009-08-12
CA2355607A1 (en) 2000-06-22
AU2004205164A1 (en) 2004-09-16
JP2002538771A (ja) 2002-11-19
PT1144006E (pt) 2007-12-11
EP1144006A4 (en) 2004-11-24
AU2199600A (en) 2000-07-03
HK1041207B (en) 2007-12-28
EP1144006A2 (en) 2001-10-17
ATE375802T1 (de) 2007-11-15
DK1144006T3 (da) 2007-11-26
DE69937369D1 (de) 2007-11-29
HK1041207A1 (en) 2002-07-05
WO2000035409A3 (en) 2000-09-14
AU773175B2 (en) 2004-05-20
ES2296416T3 (es) 2008-04-16
CY1107858T1 (el) 2013-06-19
EP1144006B1 (en) 2007-10-17
MXPA01006097A (es) 2002-04-15
WO2000035409A2 (en) 2000-06-22
EP2088158A3 (en) 2010-01-20

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Legal Events

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8364 No opposition during term of opposition