ATE375802T1 - Ccr5 antikörper pa14 - Google Patents

Ccr5 antikörper pa14

Info

Publication number
ATE375802T1
ATE375802T1 AT99966466T AT99966466T ATE375802T1 AT E375802 T1 ATE375802 T1 AT E375802T1 AT 99966466 T AT99966466 T AT 99966466T AT 99966466 T AT99966466 T AT 99966466T AT E375802 T1 ATE375802 T1 AT E375802T1
Authority
AT
Austria
Prior art keywords
monoclonal antibody
binds
fragment
ccr5 antibodies
antibody
Prior art date
Application number
AT99966466T
Other languages
English (en)
Inventor
William Olson
Paul Maddon
Original Assignee
Progenics Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Progenics Pharm Inc filed Critical Progenics Pharm Inc
Application granted granted Critical
Publication of ATE375802T1 publication Critical patent/ATE375802T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • AIDS & HIV (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT99966466T 1998-12-16 1999-12-16 Ccr5 antikörper pa14 ATE375802T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11253298P 1998-12-16 1998-12-16
US21279398A 1998-12-16 1998-12-16

Publications (1)

Publication Number Publication Date
ATE375802T1 true ATE375802T1 (de) 2007-11-15

Family

ID=26810060

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99966466T ATE375802T1 (de) 1998-12-16 1999-12-16 Ccr5 antikörper pa14

Country Status (13)

Country Link
EP (2) EP1144006B1 (de)
JP (1) JP2002538771A (de)
AT (1) ATE375802T1 (de)
AU (3) AU773175B2 (de)
CA (1) CA2355607A1 (de)
CY (1) CY1107858T1 (de)
DE (1) DE69937369T2 (de)
DK (1) DK1144006T3 (de)
ES (1) ES2296416T3 (de)
HK (1) HK1041207B (de)
MX (1) MXPA01006097A (de)
PT (1) PT1144006E (de)
WO (1) WO2000035409A2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6261763B1 (en) 1995-06-07 2001-07-17 Progenics Pharmaceuticals, Inc. Fluorescence resonance energy transfer screening assay for the identification of compounds that are capable of abrogating macrophage-tropic HIV-1 cell fusion
US7118859B2 (en) 1996-01-17 2006-10-10 Progenics Pharmaceuticals, Inc. Methods for inhibiting HIV-1 infection
AU2265701A (en) * 1999-12-16 2001-06-25 Tanox, Inc. Anti-hiv-1 conjugates for treatment of hiv disease
US7138119B2 (en) * 2000-09-15 2006-11-21 Progenics Pharmaceuticals, Inc. Compositions and methods for inhibition of HIV-1 infection
US7060273B2 (en) 2001-04-06 2006-06-13 Progenics Pharmaceuticals, Inc. Methods for inhibiting HIV-1 infection
US20020146415A1 (en) * 2001-04-06 2002-10-10 Olson William C. Methods for inhibiting HIV-1 infection
DE60203324T2 (de) * 2001-12-21 2006-04-06 Micromet Ag Einzelne und duale anti-cd4-rantes chemokin/zytokin konstrukte
US7122185B2 (en) 2002-02-22 2006-10-17 Progenics Pharmaceuticals, Inc. Anti-CCR5 antibody
DK1478738T3 (da) * 2002-02-22 2009-03-09 Pdl Biopharma Inc Anti-CCR5-antistof
TW200720289A (en) 2005-04-01 2007-06-01 Hoffmann La Roche Antibodies against CCR5 and uses thereof
CN101410414A (zh) * 2006-01-30 2009-04-15 弗·哈夫曼-拉罗切有限公司 用于治疗hiv的具有协同作用的组合物
TW200817438A (en) 2006-08-17 2008-04-16 Hoffmann La Roche A conjugate of an antibody against CCR5 and an antifusogenic peptide
KR101105610B1 (ko) 2006-08-17 2012-01-18 에프. 호프만-라 로슈 아게 Ｃｃｒ５ 에 대한 항체 및 항푸소제닉 펩타이드의 컨쥬게이트
WO2008037419A1 (en) 2006-09-29 2008-04-03 F. Hoffmann-La Roche Ag Antibodies against ccr5 and uses thereof
CL2008000707A1 (es) 2007-03-13 2008-09-22 Hoffmann La Roche Conjugado de polipeptidos antifusogenicos y polipeptidos derivados de la cabeza globular del factor del complemento c1q; composicion farmaceutica que lo comprende; su uso para tratar infecciones viricas; y metodo de produccion.
WO2013024022A1 (en) 2011-08-12 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for treatment of pulmonary hypertension
US11629196B2 (en) 2020-04-27 2023-04-18 Incelldx, Inc. Method of treating SARS-CoV-2-associated hypercytokinemia by administering a human monoclonal antibody (PRO-140) that inhibits CCR5/CCL5 binding interactions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3375697A (en) * 1996-05-28 1998-01-05 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Cc chemokine receptor 5, antibodies thereto, transgenic animals
CA2257991A1 (en) * 1996-06-14 1997-12-18 Progenics Pharmaceuticals, Inc. Uses of a chemokine receptor for inhibiting hiv-1 infection
US6528625B1 (en) * 1996-10-28 2003-03-04 Millennium Pharmaceuticals, Inc. Anti-CCR5 antibodies and kits comprising same

Also Published As

Publication number Publication date
JP2002538771A (ja) 2002-11-19
DK1144006T3 (da) 2007-11-26
EP2088158A2 (de) 2009-08-12
EP1144006B1 (de) 2007-10-17
MXPA01006097A (es) 2002-04-15
DE69937369D1 (de) 2007-11-29
DE69937369T2 (de) 2008-07-24
AU2199600A (en) 2000-07-03
AU2004205165A1 (en) 2004-09-16
WO2000035409A2 (en) 2000-06-22
HK1041207A1 (en) 2002-07-05
EP2088158A3 (de) 2010-01-20
AU773175B2 (en) 2004-05-20
HK1041207B (en) 2007-12-28
EP1144006A4 (de) 2004-11-24
ES2296416T3 (es) 2008-04-16
EP1144006A2 (de) 2001-10-17
CY1107858T1 (el) 2013-06-19
PT1144006E (pt) 2007-12-11
CA2355607A1 (en) 2000-06-22
WO2000035409A3 (en) 2000-09-14
AU2004205164A1 (en) 2004-09-16

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Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee