DE69936186T2 - Dihydroartemisinin-Formulierung zur Behandlung von verschiedenen Typen von Malaria - Google Patents

Dihydroartemisinin-Formulierung zur Behandlung von verschiedenen Typen von Malaria Download PDF

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Publication number
DE69936186T2
DE69936186T2 DE69936186T DE69936186T DE69936186T2 DE 69936186 T2 DE69936186 T2 DE 69936186T2 DE 69936186 T DE69936186 T DE 69936186T DE 69936186 T DE69936186 T DE 69936186T DE 69936186 T2 DE69936186 T2 DE 69936186T2
Authority
DE
Germany
Prior art keywords
formulation according
formulation
dihydroartemisinin
malaria
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69936186T
Other languages
German (de)
English (en)
Other versions
DE69936186D1 (de
Inventor
Dharam Chand Lucknow 226 015 Jain
Rajendra Singh Lucknow 226 015 Bhakuni
Ram Prakash Lucknow 226 015 Sharma
Sushil Lucknow 226 015 Kumar
Guru Prakash Lucknow 226 001 Dutta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Council of Scientific and Industrial Research
Original Assignee
Council of Scientific and Industrial Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Council of Scientific and Industrial Research filed Critical Council of Scientific and Industrial Research
Application granted granted Critical
Publication of DE69936186D1 publication Critical patent/DE69936186D1/de
Publication of DE69936186T2 publication Critical patent/DE69936186T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69936186T 1999-02-12 1999-03-12 Dihydroartemisinin-Formulierung zur Behandlung von verschiedenen Typen von Malaria Expired - Lifetime DE69936186T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
INDE23699 1999-02-12
IN236DE1999 IN191696B (enExample) 1999-02-12 1999-02-12

Publications (2)

Publication Number Publication Date
DE69936186D1 DE69936186D1 (de) 2007-07-12
DE69936186T2 true DE69936186T2 (de) 2008-01-24

Family

ID=11088855

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69936186T Expired - Lifetime DE69936186T2 (de) 1999-02-12 1999-03-12 Dihydroartemisinin-Formulierung zur Behandlung von verschiedenen Typen von Malaria

Country Status (9)

Country Link
US (2) US6214864B1 (enExample)
EP (1) EP1034794B1 (enExample)
JP (1) JP3686281B2 (enExample)
CN (1) CN1197568C (enExample)
AU (1) AU763680B2 (enExample)
DE (1) DE69936186T2 (enExample)
IN (1) IN191696B (enExample)
MY (1) MY129619A (enExample)
ZA (1) ZA992354B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN191696B (enExample) * 1999-02-12 2003-12-20 Council Scient Ind Res
WO2001074353A1 (en) * 2000-03-31 2001-10-11 Council Of Scientific And Industrial Research A synergistic anti-malarial formulation
JP2005529938A (ja) * 2002-06-06 2005-10-06 ユニバーシティ オブ ワシントン 癌の発症を予防または遅延するためのアルテミシニン様化合物を使用する方法
ATE536887T1 (de) * 2002-06-06 2011-12-15 Univ Washington Kovalente konjugate zwischen mit artemisinin verwandten endoperoxiden und eisentragenden proteinen und anwendungsverfahren
CN1814601A (zh) * 2005-02-04 2006-08-09 中国科学院上海药物研究所 具有免疫抑制作用的青蒿素衍生物及药物组合物
WO2007105048A1 (en) * 2006-03-10 2007-09-20 Council Of Scientific And Industrial Research A process for one pot conversion of artemisinin into artelinic acid
EP3065796B1 (en) 2013-11-08 2020-04-15 ExThera Medical Corporation Methods for diagnosing infectious diseases using adsorption media
CN106265481B (zh) * 2016-08-31 2020-06-19 昆药集团股份有限公司 一种蒿甲醚栓剂及其制备方法
CN113552274B (zh) * 2021-07-23 2022-11-29 重庆市中药研究院 一种青蒿素副产物高效液相指纹图谱的建立及含量测定方法
CN114617842A (zh) * 2022-01-05 2022-06-14 沈阳农业大学 一种双氢青蒿素-羧甲基纤维素钠溶液的制备方法及其应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN166154B (enExample) * 1987-05-08 1990-03-24 Hoechst India
US4816478A (en) * 1987-08-24 1989-03-28 Thornfeldt Carl R Treatment of acquired immunodeficiency syndrome
US5225427A (en) * 1988-10-04 1993-07-06 Hoechst Aktiengesellschaft 10-substituted ether derivatives of dihydroartemisinin, process for their preparation and their use as antiprotozoal agents
CN1041595A (zh) * 1988-10-04 1990-04-25 赫彻斯特股份公司 新蒿属素衍生物，其制法及其作为抗原虫剂的应用，
TW198722B (enExample) * 1990-05-07 1993-01-21 Hoechst Ag
US5486535A (en) * 1990-06-26 1996-01-23 Regents Of The University Of Colorado Method for treating toxoplasmosis
CN1058717A (zh) * 1990-08-08 1992-02-19 中国人民解放军军事医学科学院微生物流行病研究所 抗疟新药—复方蒿甲醚及其制备方法
JPH09512794A (ja) * 1994-04-07 1997-12-22 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー マラリアの治療用のハロファントリン遊離塩基および組成物
GB9622427D0 (en) * 1996-10-28 1997-01-08 Pharma Mar Sa Antimalarial drugs
IN188174B (enExample) * 1997-03-17 2002-08-31 Council Scient Ind Res
IN191696B (enExample) * 1999-02-12 2003-12-20 Council Scient Ind Res

Also Published As

Publication number Publication date
JP2000239165A (ja) 2000-09-05
US6214864B1 (en) 2001-04-10
IN191696B (enExample) 2003-12-20
EP1034794B1 (en) 2007-05-30
CN1197568C (zh) 2005-04-20
AU763680B2 (en) 2003-07-31
AU2250799A (en) 2000-08-17
CN1262927A (zh) 2000-08-16
US6362219B1 (en) 2002-03-26
JP3686281B2 (ja) 2005-08-24
EP1034794A1 (en) 2000-09-13
ZA992354B (en) 2000-10-10
DE69936186D1 (de) 2007-07-12
MY129619A (en) 2007-04-30

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