DE69935085T2 - Verfahren und Zusammensetzung zur Hemmung des neoplastischen Zellwachstums - Google Patents
Verfahren und Zusammensetzung zur Hemmung des neoplastischen Zellwachstums Download PDFInfo
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- DE69935085T2 DE69935085T2 DE69935085T DE69935085T DE69935085T2 DE 69935085 T2 DE69935085 T2 DE 69935085T2 DE 69935085 T DE69935085 T DE 69935085T DE 69935085 T DE69935085 T DE 69935085T DE 69935085 T2 DE69935085 T2 DE 69935085T2
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- 208000013013 vulvar carcinoma Diseases 0.000 description 1
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- 238000001262 western blot Methods 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
- 229910052727 yttrium Inorganic materials 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Toxicology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (18)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11329698P | 1998-12-22 | 1998-12-22 | |
| US113296P | 1998-12-22 | ||
| PCT/US1999/005028 WO1999046281A2 (en) | 1998-03-10 | 1999-03-08 | Novel polypeptides and nucleic acids encoding the same |
| WOPCT/US99/05028 | 1999-03-08 | ||
| US13023299P | 1999-04-21 | 1999-04-21 | |
| US130232P | 1999-04-21 | ||
| US13144599P | 1999-04-28 | 1999-04-28 | |
| US131445P | 1999-04-28 | ||
| US13428799P | 1999-05-14 | 1999-05-14 | |
| US134287P | 1999-05-14 | ||
| US14475899P | 1999-07-20 | 1999-07-20 | |
| US144758P | 1999-07-20 | ||
| US14569899P | 1999-07-26 | 1999-07-26 | |
| US145698P | 1999-07-26 | ||
| WOPCT/US99/21090 | 1999-09-15 | ||
| PCT/US1999/021090 WO2000015796A2 (en) | 1998-09-16 | 1999-09-15 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| WOPCT/US99/21547 | 1999-09-15 | ||
| PCT/US1999/021547 WO2000015797A2 (en) | 1998-09-17 | 1999-09-15 | Compositions and methods for the treatment of immune related diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69935085D1 DE69935085D1 (de) | 2007-03-22 |
| DE69935085T2 true DE69935085T2 (de) | 2007-08-23 |
Family
ID=27557838
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69935085T Expired - Lifetime DE69935085T2 (de) | 1998-12-22 | 1999-12-02 | Verfahren und Zusammensetzung zur Hemmung des neoplastischen Zellwachstums |
| DE69940964T Expired - Lifetime DE69940964D1 (de) | 1998-12-22 | 1999-12-02 | Verfahren und Zusammensetzungen zur Hemmung des neoplastischen Zellenwachstums |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69940964T Expired - Lifetime DE69940964D1 (de) | 1998-12-22 | 1999-12-02 | Verfahren und Zusammensetzungen zur Hemmung des neoplastischen Zellenwachstums |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1141284A2 (enExample) |
| JP (5) | JP3993746B2 (enExample) |
| KR (1) | KR100499600B1 (enExample) |
| AT (2) | ATE432987T1 (enExample) |
| AU (1) | AU768230B2 (enExample) |
| CA (1) | CA2353799A1 (enExample) |
| DE (2) | DE69935085T2 (enExample) |
| DK (1) | DK1484338T3 (enExample) |
| ES (2) | ES2281704T3 (enExample) |
| IL (3) | IL143031A0 (enExample) |
| MX (1) | MXPA01006330A (enExample) |
| PT (1) | PT1484338E (enExample) |
| WO (1) | WO2000037638A2 (enExample) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO1999066041A1 (en) | 1998-06-16 | 1999-12-23 | Human Genome Sciences, Inc. | 94 human secreted proteins |
| US6392019B1 (en) | 1997-11-22 | 2002-05-21 | John Ford | Antibodies specific for EGF motif proteins |
| US6808890B2 (en) | 1999-07-28 | 2004-10-26 | Nuvelo, Inc. | Method of detecting a cancerous cell expressing EGFL6, and EGF mutif protein |
| US8088386B2 (en) | 1998-03-20 | 2012-01-03 | Genentech, Inc. | Treatment of complement-associated disorders |
| US8007798B2 (en) | 1997-11-21 | 2011-08-30 | Genentech, Inc. | Treatment of complement-associated disorders |
| US7192589B2 (en) * | 1998-09-16 | 2007-03-20 | Genentech, Inc. | Treatment of inflammatory disorders with STIgMA immunoadhesins |
| US7419663B2 (en) | 1998-03-20 | 2008-09-02 | Genentech, Inc. | Treatment of complement-associated disorders |
| JP2002504308A (ja) | 1997-11-22 | 2002-02-12 | ハイセック インコーポレイテッド | 胎児肝−脾臓のｃＤＮＡライブラリーから得られた新規ＥＧＦモチーフタンパク質 |
| EP1251139A3 (en) * | 1998-04-08 | 2002-12-18 | Genentech, Inc. | Human mindin-like protein and nucleic acids encoding it |
| US6960433B1 (en) | 1998-10-19 | 2005-11-01 | Diadexus, Inc. | Method of diagnosing, monitoring, staging, imaging and treating prostate cancer |
| AU2507700A (en) | 1999-01-15 | 2000-08-01 | Biogen, Inc. | Antagonists of tweak and of tweak receptor and their use to treat immunological disorders |
| AU768694B2 (en) * | 1999-03-08 | 2004-01-08 | Genentech Inc. | Promotion or inhibition of angiogenesis and cardiovascularization |
| AU4011300A (en) * | 1999-07-20 | 2001-02-05 | Genentech Inc. | Compositions and methods for the treatment of immune related diseases |
| MXPA02005758A (es) * | 1999-12-09 | 2002-09-18 | Sankyo Co | Metodo para evaluar un remedio o agente preventivo para hiperlipidemia. |
| PL356887A1 (en) * | 2000-01-12 | 2004-07-12 | Yale University | Nogo receptor-mediated blockade of axonal growth |
| US7119165B2 (en) | 2000-01-12 | 2006-10-10 | Yale University | Nogo receptor-mediated blockade of axonal growth |
| US6943146B2 (en) | 2000-05-08 | 2005-09-13 | Biogen Idec Ma Inc. | Method for promoting neovascularization |
| US7208151B2 (en) | 2001-09-12 | 2007-04-24 | Biogen Idec Ma Inc. | Tweak receptor agonists as anti-angiogenic agents |
| DE60141409D1 (de) | 2000-10-06 | 2010-04-08 | Biogen Idec Inc | Homologe des nogo rezeptors |
| US20020111302A1 (en) * | 2000-11-30 | 2002-08-15 | Y. Tom Tang | Novel nucleic acids and polypeptides |
| SI1997512T1 (sl) | 2002-04-09 | 2014-03-31 | Biogen Idec Ma Inc. | Postopki za zdravljenje stanj, povezanih s TWEAK-om |
| CA2391438A1 (en) * | 2002-05-01 | 2003-11-01 | Procyon Biopharma Inc. | Psp94 diagnostic reagents and assays |
| US7294704B2 (en) | 2003-08-15 | 2007-11-13 | Diadexus, Inc. | Pro108 antibody compositions and methods of use and use of Pro108 to assess cancer risk |
| DK2529619T3 (en) | 2005-02-17 | 2016-01-11 | Biogen Ma Inc | Treatment of neurological disorders |
| CA2607697C (en) | 2005-05-10 | 2015-01-06 | Biogen Idec Ma Inc. | Treating and evaluating inflammatory disorders |
| WO2006138219A2 (en) | 2005-06-13 | 2006-12-28 | Biogen Idec Ma Inc. | Methods of diagnosis / prognosis of inflammatory conditions |
| EP1904091A4 (en) | 2005-07-07 | 2009-12-23 | Univ Yale | COMPOSITIONS AND METHODS FOR SUPPRESSING THE INHIBITION OF AXON GROWTH |
| ES2551202T5 (es) | 2005-11-04 | 2018-11-30 | Genentech, Inc. | Uso de inhibidores de la vía del complemento para tratar enfermedades oculares |
| EP2010226B1 (en) * | 2006-04-07 | 2014-01-15 | The Research Foundation of State University of New York | Transcobalamin receptor polypeptides, nucleic acids, and modulators thereof, and related methods of use in modulating cell growth and treating cancer and cobalamin deficiency |
| US9044461B2 (en) | 2006-04-07 | 2015-06-02 | The Research Foundation Of State University Of New York | Transcobalamin receptor polypeptides, nucleic acids, and modulators thereof, and related methods of use in modulating cell growth and treating cancer and cobalamin deficiency |
| US7776573B2 (en) | 2006-06-01 | 2010-08-17 | Genentech, Inc. | Crystal structure of CRIg and C3b:CRIg complex |
| CN106084054A (zh) | 2006-11-02 | 2016-11-09 | 健泰科生物技术公司 | 人源化的抗‑d因子抗体 |
| AR066660A1 (es) | 2007-05-23 | 2009-09-02 | Genentech Inc | Prevencion y tratamiento de condiciones del ojo asociadas con su complemento |
| CR20170001A (es) | 2008-04-28 | 2017-08-10 | Genentech Inc | Anticuerpos anti factor d humanizados |
| LT2280996T (lt) | 2008-05-06 | 2016-12-12 | Genentech, Inc. | Subrendusio giminingumo crig variantai |
| US9120858B2 (en) | 2011-07-22 | 2015-09-01 | The Research Foundation Of State University Of New York | Antibodies to the B12-transcobalamin receptor |
| CR20160132A (es) | 2013-08-12 | 2016-08-25 | Genentech Inc | Composiciones y método para tratar condiciones asociadas con el complemento |
| SG11201608868PA (en) | 2014-05-01 | 2016-11-29 | Genentech Inc | Anti-factor d antibody variants and uses thereof |
| EP3368074A2 (en) | 2015-10-30 | 2018-09-05 | Hoffmann-La Roche AG | Anti-factor d antibodies and conjugates |
| EP3368090A1 (en) | 2015-10-30 | 2018-09-05 | H. Hoffnabb-La Roche Ag | Anti-factor d antibody variant conjugates and uses thereof |
| CN114835774B (zh) * | 2022-06-29 | 2022-09-27 | 中国农业大学 | 辣椒籽分离的寡肽msl及其在预防或治疗癌症中的应用 |
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| NZ226799A (en) * | 1987-11-06 | 1991-08-27 | Oncogen | Breast cancer inhibitory factor and method for inhibiting proliferation of neoplastic cells and compositions therefor |
| US5814307A (en) * | 1989-04-10 | 1998-09-29 | Bristol-Myers Squibb Company | Method for regulating cell growth, leukocyte differentiation and tumor cell growth using Oncostatin M to stimulate synthesis of IL-6 |
| US5416192A (en) * | 1990-04-03 | 1995-05-16 | Bristol-Myers Squibb Company | Epithelins: novel cysteine-rich growth modulating proteins |
| US5028099A (en) * | 1990-08-08 | 1991-07-02 | Bertucco Leonard J | Trash recycling container |
| US6030831A (en) * | 1997-09-19 | 2000-02-29 | Genetech, Inc. | Tie ligand homologues |
| AU3661199A (en) * | 1998-04-27 | 1999-11-16 | Zymogenetics Inc. | Novel polypeptide growth factors and materials and methods for making them |
| SV1999000069A (es) * | 1998-06-02 | 2000-04-11 | Lilly Co Eli | Angiopoyetina relacionada con secuencia del gen 3 en la cicatrizacion de la cara ref. x-12261 |
| JP7039446B2 (ja) * | 2018-11-29 | 2022-03-22 | 株式会社東芝 | 電子装置 |
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1999
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- 1999-12-02 DE DE69935085T patent/DE69935085T2/de not_active Expired - Lifetime
- 1999-12-02 KR KR10-2001-7007850A patent/KR100499600B1/ko not_active Expired - Fee Related
- 1999-12-02 ES ES04007617T patent/ES2281704T3/es not_active Expired - Lifetime
- 1999-12-02 CA CA002353799A patent/CA2353799A1/en not_active Abandoned
- 1999-12-02 AT AT07001711T patent/ATE432987T1/de not_active IP Right Cessation
- 1999-12-02 DE DE69940964T patent/DE69940964D1/de not_active Expired - Lifetime
- 1999-12-02 WO PCT/US1999/028565 patent/WO2000037638A2/en not_active Ceased
- 1999-12-02 IL IL14303199A patent/IL143031A0/xx not_active IP Right Cessation
- 1999-12-02 AU AU17499/00A patent/AU768230B2/en not_active Expired
- 1999-12-02 EP EP99960644A patent/EP1141284A2/en not_active Withdrawn
- 1999-12-02 ES ES07001711T patent/ES2327785T3/es not_active Expired - Lifetime
- 1999-12-02 PT PT04007617T patent/PT1484338E/pt unknown
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- 1999-12-02 DK DK04007617T patent/DK1484338T3/da active
- 1999-12-02 MX MXPA01006330A patent/MXPA01006330A/es not_active Application Discontinuation
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2005
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- 2005-03-10 JP JP2005066569A patent/JP4037876B2/ja not_active Expired - Lifetime
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2007
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- 2007-09-20 IL IL186153A patent/IL186153A0/en unknown
- 2007-09-20 IL IL186154A patent/IL186154A0/en unknown
Also Published As
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| EP1141284A2 (en) | 2001-10-10 |
| DK1484338T3 (da) | 2007-06-11 |
| JP2007291116A (ja) | 2007-11-08 |
| DE69940964D1 (de) | 2009-07-16 |
| JP2005237383A (ja) | 2005-09-08 |
| IL186153A0 (en) | 2008-01-20 |
| JP2005245451A (ja) | 2005-09-15 |
| ATE432987T1 (de) | 2009-06-15 |
| ES2327785T3 (es) | 2009-11-03 |
| DE69935085D1 (de) | 2007-03-22 |
| CA2353799A1 (en) | 2000-06-29 |
| KR20010084882A (ko) | 2001-09-06 |
| KR100499600B1 (ko) | 2005-07-07 |
| PT1484338E (pt) | 2007-05-31 |
| JP3993746B2 (ja) | 2007-10-17 |
| ES2281704T3 (es) | 2007-10-01 |
| IL143031A0 (en) | 2002-04-21 |
| WO2000037638A3 (en) | 2000-11-09 |
| ATE353339T1 (de) | 2007-02-15 |
| JP4037876B2 (ja) | 2008-01-23 |
| JP2003529317A (ja) | 2003-10-07 |
| AU1749900A (en) | 2000-07-12 |
| AU768230B2 (en) | 2003-12-04 |
| WO2000037638A2 (en) | 2000-06-29 |
| MXPA01006330A (es) | 2002-07-02 |
| JP2007222180A (ja) | 2007-09-06 |
| IL186154A0 (en) | 2008-01-20 |
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