DE69932834D1 - Chi-Conotoxinpeptide als Inhibitoren neuronaler Amintransporter - Google Patents

Chi-Conotoxinpeptide als Inhibitoren neuronaler Amintransporter

Info

Publication number
DE69932834D1
DE69932834D1 DE69932834T DE69932834T DE69932834D1 DE 69932834 D1 DE69932834 D1 DE 69932834D1 DE 69932834 T DE69932834 T DE 69932834T DE 69932834 T DE69932834 T DE 69932834T DE 69932834 D1 DE69932834 D1 DE 69932834D1
Authority
DE
Germany
Prior art keywords
chi
inhibitors
conotoxin peptides
amine transporters
peptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69932834T
Other languages
English (en)
Other versions
DE69932834T2 (de
Inventor
James Lewis
Francis Alewood
Andrew Sharpe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xenome Ltd
Original Assignee
Xenome Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3810492&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69932834(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Xenome Ltd filed Critical Xenome Ltd
Publication of DE69932834D1 publication Critical patent/DE69932834D1/de
Application granted granted Critical
Publication of DE69932834T2 publication Critical patent/DE69932834T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Addiction (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69932834T 1998-10-02 1999-10-01 Neue Peptide Expired - Lifetime DE69932834T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPP6274A AUPP627498A0 (en) 1998-10-02 1998-10-02 Novel peptides - i
AUPP627498 1998-10-02
PCT/AU1999/000844 WO2000020444A1 (en) 1998-10-02 1999-10-01 Novel peptides

Publications (2)

Publication Number Publication Date
DE69932834D1 true DE69932834D1 (de) 2006-09-28
DE69932834T2 DE69932834T2 (de) 2007-08-23

Family

ID=3810492

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69932834T Expired - Lifetime DE69932834T2 (de) 1998-10-02 1999-10-01 Neue Peptide

Country Status (13)

Country Link
US (4) US6794361B1 (de)
EP (1) EP1117682B1 (de)
JP (2) JP4447783B2 (de)
AT (1) ATE336501T1 (de)
AU (1) AUPP627498A0 (de)
CA (1) CA2344765A1 (de)
CY (1) CY1110381T1 (de)
DE (1) DE69932834T2 (de)
DK (1) DK1117682T3 (de)
ES (1) ES2268885T3 (de)
NZ (1) NZ510813A (de)
PT (1) PT1117682E (de)
WO (1) WO2000020444A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP627498A0 (en) * 1998-10-02 1998-10-22 University Of Queensland, The Novel peptides - i
US6767896B1 (en) 1999-01-29 2004-07-27 Cognetix, Inc. Conotoxin peptides
AU2002245340A1 (en) * 2001-01-29 2002-08-12 Cognetix, Inc. B-superfamily conotoxins
AU2003302610B2 (en) 2002-12-02 2008-03-20 Xenome Ltd Novel chi-conotoxin peptides (-II)
EP1572725B1 (de) * 2002-12-02 2012-02-29 Xenome Ltd Chi-conotoxinpeptide mit einer n-terminalen pyroglutaminsäure
EP1791857A4 (de) * 2004-09-09 2009-04-08 Univ Singapore Konformationswechsel in der toxinfaltung und verwendungen dafür
US8188048B2 (en) 2006-06-23 2012-05-29 Xenome Limited Combination therapy
CN103372198B (zh) * 2012-04-12 2016-04-06 同济大学 用于抑制病毒的多肽抑制剂
JP6731044B2 (ja) 2015-05-22 2020-07-29 クレムソン・ユニバーシティ・リサーチ・ファウンデーション 生物付着の抑止において用いるためのコノトキシンペプチド
US10704035B2 (en) 2015-08-27 2020-07-07 President And Fellows Of Harvard College Compositions and methods for treatment of pain

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5051403A (en) 1989-11-22 1991-09-24 Neurex Corporation Method of treating ischemia-related neuronal damage
CA2061665C (en) 1991-02-25 2002-04-16 Mark Mortensen Foreman Treatment of lower urinary tract disorders
DE69225499T2 (de) * 1991-12-30 1999-02-04 Neurex Corp Methoden zur erzeugung von analgesie und zur verstärkung von opiat-analgesie
DK0758900T3 (da) * 1994-05-09 2002-07-29 William J Binder Botulinumtoksin til reduktion af migræne-hovedpinesmerter
RU2158601C2 (ru) 1994-11-03 2000-11-10 Новартис Аг Новые лекарственные формы циклоспорина для орального применения с простым составом и высокой биодоступностью и способ их получения
WO1996040064A1 (en) 1995-06-07 1996-12-19 Nexstar Pharmaceuticals, Inc. Liposomal cyclosporin formulations as agents for immunosuppression and multiple drug resistant indications
DK1336409T3 (da) 1995-06-27 2007-08-13 Eisai R&D Man Co Ltd Sammensætninger af formuleringer til fremstilling af analgesimidler og til hæmning af fremadskridende neuropatiske smertelidelser
ZA971525B (en) 1996-02-22 1997-10-21 Neurosearch As Tropane derivatives, their preparation and use.
GB9614902D0 (en) 1996-07-16 1996-09-04 Rhodes John Sustained release composition
CZ288739B6 (cs) 1996-08-01 2001-08-15 Galena, A. S. Cyklosporin obsahující léčivé přípravky
JP2001505878A (ja) 1996-11-18 2001-05-08 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデーション 心臓血管剤としてのコノトキシンペプチドＩｍＩおよびＭＩＩの使用
ATE248147T1 (de) 1997-05-14 2003-09-15 Neurosearch As Piperidine derivate als inhibitoren der neurotransmitter-wiederaufbaunahme
AUPP627498A0 (en) * 1998-10-02 1998-10-22 University Of Queensland, The Novel peptides - i
WO2000044769A1 (en) 1999-01-29 2000-08-03 University Of Utah Research Foundation Conotoxin peptides
AU2003302610B2 (en) * 2002-12-02 2008-03-20 Xenome Ltd Novel chi-conotoxin peptides (-II)
EP1572725B1 (de) * 2002-12-02 2012-02-29 Xenome Ltd Chi-conotoxinpeptide mit einer n-terminalen pyroglutaminsäure

Also Published As

Publication number Publication date
WO2000020444A1 (en) 2000-04-13
JP2002526098A (ja) 2002-08-20
CY1110381T1 (el) 2015-04-29
DK1117682T3 (da) 2006-12-27
CA2344765A1 (en) 2000-04-13
US7326682B2 (en) 2008-02-05
JP2010046088A (ja) 2010-03-04
US6794361B1 (en) 2004-09-21
US7994128B2 (en) 2011-08-09
EP1117682A4 (de) 2001-12-12
DE69932834T2 (de) 2007-08-23
US20090275498A1 (en) 2009-11-05
JP4447783B2 (ja) 2010-04-07
EP1117682A1 (de) 2001-07-25
ES2268885T3 (es) 2007-03-16
PT1117682E (pt) 2006-12-29
US20050054827A1 (en) 2005-03-10
US20120277166A1 (en) 2012-11-01
EP1117682B1 (de) 2006-08-16
NZ510813A (en) 2003-08-29
ATE336501T1 (de) 2006-09-15
AUPP627498A0 (en) 1998-10-22

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